Linezolid-containing regimens for the treatment of drug-resistant tuberculosis in South African children

International Journal of Tuberculosis and Lung Disease

Volumn 16, Issue 12, 2012, Pages 1588-1593

  Rose, Penelope C ^a   Hallbauer, U M ^b,c   Seddon, J A ^a,d   Hesseling, A C ^a   Schaaf, H S ^a,e  

^a STELLENBOSCH UNIVERSITY   (South Africa)

^b UNIVERSITY OF THE FREE STATE   (South Africa)

^c Pelonomi Hospital   (South Africa)

^d LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^e STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

Linezolid; Long term; Paediatric; TB

Indexed keywords

ABACAVIR; AMIKACIN; AMINOSALICYLIC ACID; AMOXICILLIN PLUS CLAVULANIC ACID; CAPREOMYCIN; CLARITHROMYCIN; CLOFAZIMINE; EFAVIRENZ; ETHAMBUTOL; ETHIONAMIDE; ISONIAZID; KANAMYCIN; LAMIVUDINE; LINEZOLID; MOXIFLOXACIN; OFLOXACIN; PYRAZINAMIDE; RIFAMPICIN; STAVUDINE; STREPTOMYCIN; TERIZIDONE; ZIDOVUDINE;

ADOLESCENT; ANEMIA; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM CULTURE; CHILD; CHILD HEALTH CARE; CLINICAL ARTICLE; DOSE RESPONSE; DRUG RESISTANT TUBERCULOSIS; DRUG SUBSTITUTION; DRUG TREATMENT FAILURE; DRUG WITHDRAWAL; EXTENSIVELY DRUG RESISTANT TUBERCULOSIS; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYPOTHYROIDISM; INFANT; LACTIC ACIDOSIS; LEUKOPENIA; MALE; MILIARY TUBERCULOSIS; MIXED INFECTION; MULTIDRUG RESISTANT TUBERCULOSIS; NEUTROPENIA; PANCREATITIS; PERIPHERAL NEUROPATHY; PRESCHOOL CHILD; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCHOOL CHILD; SIDE EFFECT; SOUTH AFRICA; TREATMENT OUTCOME; TUBERCULOUS MENINGITIS;

ACETAMIDES; ADOLESCENT; AGE FACTORS; ANTI-HIV AGENTS; ANTITUBERCULAR AGENTS; CHILD; CHILD, PRESCHOOL; COINFECTION; COST SAVINGS; DRUG COSTS; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS; FEMALE; HIV INFECTIONS; HUMANS; INFANT; MALE; MYCOBACTERIUM TUBERCULOSIS; OXAZOLIDINONES; RETROSPECTIVE STUDIES; SOUTH AFRICA; SPUTUM; TIME FACTORS; TREATMENT OUTCOME; TUBERCULOSIS, MULTIDRUG-RESISTANT; TUBERCULOSIS, PULMONARY;

EID: 84870223120     PISSN: 10273719     EISSN: None     Source Type: Journal    
DOI: 10.5588/ijtld.12.0322     Document Type: Article

References (24)

1. World Health Organization. Global tuberculosis control: WHO report 2011. WHO/HTM/MTB/2011.16. Geneva, Switzerland: WHO, 2011.
2. World Health Organization. Multidrug and extensively drug-resistant TB (M/XDR-TB) 2010 global report on surveillance and response. WHO/HTM/TB/2010.3. Geneva, Switzerland: WHO, 2010.
3. Global Alliance for TB Drug Development. Handbook of antituberculosis agents. Tuberculosis. Vol 88. New York, NY, USA: Elsevier, 2008: pp 85-170.
4. World Health Organization. Guidelines for programmatic management of DR-TB. 2011 update. WHO/HTM/TB/2011.6. Geneva, Switzerland: WHO, 2011.
5. Anger H A, Dworkin F, Sharma S, Munsiff S S, Nilsen D M, Ahuja S D. Linezolid use for treatment of multidrug-resistant and extensively drug-resistant tuberculosis, New York City, 2000-06. J Antimicrob Chemother 2010; 65: 775-783.
6. Fortun J, Martin-Davila P, Navas E, et al. Linezolid for the treatment of multidrug-resistant tuberculosis. J Antimicrob Chemother 2005; 56: 180-185.
7. von der Lippe B, Sandven P, Brubakk O. Efficacy and safety of linezolid in multidrug resistant tuberculosis (MDR-TB) - a report of ten cases. J Infect 2006; 52: 92-96.
8. Condos R, Hadgiangelis N, Leibert E, Jacquette G, Harkin T, Rom W N. Case series report of a linezolid-containing regimen for extensively drug-resistant tuberculosis. Chest 2008; 134: 187-192.
9. Schaaf H S, Willemse M, Donald P R. Long-term linezolid treatment in a young child with extensively drug-resistant tuberculosis. Pediatr Infect Dis J 2009; 28: 748-750.
10. Pinon M, Scolfaro C, Bignamini E, et al. Two pediatric cases of multidrug-resistant tuberculosis treated with linezolid and moxifloxacin. Pediatrics 2010; 126: e1253-e1256.
11. Kjollerstrom P, Brito M J, Gouveia C, Ferreira G, Varandas L. Linezolid in the treatment of multidrug-resistant/extensively drug-resistant tuberculosis in paediatric patients: experience of a paediatric infectious diseases unit. Scand J Infect Dis 2011; 43: 556-559.
12. Chiappini E, Conti C, Galli L, de Martino M. Clinical efficacy and tolerability of linezolid in pediatric patients: a systematic review. Clin Ther 2010; 32: 66-88.
13. Garazzino S, Tovo P A. Clinical experience with linezolid in infants and children. J Antimicrob Chemother 2011; 66 (Suppl 4): iv23-iv41.
14. Cox H, Ford N. Linezolid for the treatment of complicated drug-resistant tuberculosis: a systematic review and meta-analysis. Int J Tuberc Lung Dis 2012; 16: 447-454.
15. Orenstein E W, Basu S, Shah N S, et al. Treatment outcomes among patients with multidrug-resistant tuberculosis: systematic review and meta-analysis. Lancet Infect Dis 2009; 9: 153-161.
16. Jacobson K R, Tierney D B, Jeon C Y, Mitnick C D, Murray M B. Treatment outcomes among patients with extensively drug-resistant tuberculosis: systematic review and meta-analysis. Clin Infect Dis 2010; 51: 6-14.
17. Sotgiu G, Centis R, d'Ambrosio L, et al. Efficacy, safety and tolerability of linezolid containing regimens in treating MDR-TB and XDR-TB: systematic review and meta-analysis. Eur Respir J 2012; Apr 10. [Epub ahead of print]
18. Donald P R, Schaaf H S, Schoeman J F. Tuberculous meningitis and miliary tuberculosis: the Rich focus revisited. J Infect 2005; 50: 193-195.
19. Schaaf H S, Victor T C, Engelke E, et al. Minimal inhibitory concentration of isoniazid in isoniazid-resistant Mycobacterium tuberculosis isolates from children. Eur J Clin Microbiol Infect Dis 2007; 26: 203-205.
20. Migliori G B, Eker B, Richardson M D, et al. A retrospective TBNET assessment of linezolid safety, tolerability and efficacy in multidrug-resistant tuberculosis. Eur Respir J 2009; 34: 387-393.
21. Schaaf H S, Marais B J. Management of multidrug-resistant tuberculosis in children: a survival guide for paediatricians. Paediatr Respir Rev 2011; 12: 31-38.
22. Ettehad D, Schaaf H S, Seddon J A, Cooke G S, Ford N. Treatment outcomes for children with multidrug-resistant tuberculosis: a systematic review and meta-analysis. Lancet Infect Dis 2012; 12: 449-456.
23. Seddon J A, Godfrey-Faussett P, Hesseling A C, Gie R P, Beyers N, Schaaf H S. Management of children exposed to multid-rugresistant Mycobacterium tuberculosis. Lancet Infect Dis 2012; 12: 469-479.
24. Schaaf H S, Moll A P, Dheda K. Multidrug- and extensively drug-resistant tuberculosis in Africa and South America: epidemiology, diagnosis and management in adults and children. Clin Chest Med 2009; 30: 667-683.