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Volumn 12, Issue 4, 2012, Pages 308-315

VIP as a potential therapeutic agent in Gram negative sepsis

Author keywords

Cytokine; Inflammation; Sepsis; Transcription bacteria; VIP

Indexed keywords

CYTOKINE; HIGH MOBILITY GROUP B1 PROTEIN; LIPOPOLYSACCHARIDE; PATTERN RECOGNITION RECEPTOR; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; VASOACTIVE INTESTINAL POLYPEPTIDE; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2;

EID: 84870213550     PISSN: 18715303     EISSN: 22123873     Source Type: Journal    
DOI: 10.2174/187153012803832611     Document Type: Review
Times cited : (8)

References (68)
  • 1
    • 33749027114 scopus 로고    scopus 로고
    • The epidemiology of severe sepsis in England, Wales and Northern Ireland, 1996 to 2004: Secondary analysis of a high quality clinical database, the ICNARC Case Mix Programme Database
    • Harrison, D.A.; Welch, C.A. and Eddleston, J.M. (2006) The epidemiology of severe sepsis in England, Wales and Northern Ireland, 1996 to 2004: secondary analysis of a high quality clinical database, the ICNARC Case Mix Programme Database. Crit. Care, 10, R42.
    • (2006) Crit. Care , vol.10
    • Harrison, D.A.1    Welch, C.A.2    Eddleston, J.M.3
  • 2
    • 0037451929 scopus 로고    scopus 로고
    • The epidemiology of sepsis in the United States from 1979 through 2000
    • Martin, G.S.; Mannino, D.M.; Eaton, S. and Moss, M. (2003) The epidemiology of sepsis in the United States from 1979 through 2000.N. Engl. J. Med., 348, 1546-1554.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 1546-1554
    • Martin, G.S.1    Mannino, D.M.2    Eaton, S.3    Moss, M.4
  • 3
    • 63149115281 scopus 로고    scopus 로고
    • The burden of sepsisassociated mortality in the United States from 1999 to 2005: An analysis of multiple-cause-of-death data
    • Melamed, A. and Sorvillo, F.J. (2009) The burden of sepsisassociated mortality in the United States from 1999 to 2005: an analysis of multiple-cause-of-death data. Crit. Care, 13, R28.
    • (2009) Crit. Care , vol.13
    • Melamed, A.1    Sorvillo, F.J.2
  • 4
    • 0034958947 scopus 로고    scopus 로고
    • Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
    • Angus, D.C.; Linde-zwirble, W.T.; Lidicker, J.; Clermont, G.; Carcillo, J. and Pinsky, M.R. (2001) Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care. Crit. Care Med., 29, 1303-1310.
    • (2001) Crit. Care Med. , vol.29 , pp. 1303-1310
    • Angus, D.C.1    Linde-zwirble, W.T.2    Lidicker, J.3    Clermont, G.4    Carcillo, J.5    Pinsky, M.R.6
  • 5
    • 13244288781 scopus 로고    scopus 로고
    • The "cytokine profile": A code for sepsis
    • Ulloa, L. and Tracey, K.J. (2005) The "cytokine profile": a code for sepsis. Trends Mol. Med., 11, 56-63.
    • (2005) Trends Mol. Med. , vol.11 , pp. 56-63
    • Ulloa, L.1    Tracey, K.J.2
  • 6
    • 17644401778 scopus 로고    scopus 로고
    • Role of Interleukin-6 in Mortality from and Physiologic Response to Sepsis
    • Remick, D.G.; Bolgos, G.; Copeland, S. and Siddiqui, J. (2005) Role of Interleukin-6 in Mortality from and Physiologic Response to Sepsis. Infect. Immun., 73, 2751-2757.
    • (2005) Infect. Immun. , vol.73 , pp. 2751-2757
    • Remick, D.G.1    Bolgos, G.2    Copeland, S.3    Siddiqui, J.4
  • 9
    • 79551483662 scopus 로고    scopus 로고
    • Nitrite regulation of shock
    • Cauwels, A. and Brouckaert, P. (2011) Nitrite regulation of shock. Cardiovasc. Res., 89, 553-559.
    • (2011) Cardiovasc. Res. , vol.89 , pp. 553-559
    • Cauwels, A.1    Brouckaert, P.2
  • 10
    • 34548835747 scopus 로고    scopus 로고
    • Sepsis-induced coagulation in the baboon lung is associated with decreased tissue factor pathway inhibitor
    • Tang, H.; Ivanciu, L.; Popescu, N.; Peer, G.; Hack, E.; Lupu, C.; Taylor, F.B. and Lupu, F. (2007) Sepsis-induced coagulation in the baboon lung is associated with decreased tissue factor pathway inhibitor. Am. J. Pathol., 171, 1066-1077.
    • (2007) Am. J. Pathol. , vol.171 , pp. 1066-1077
    • Tang, H.1    Ivanciu, L.2    Popescu, N.3    Peer, G.4    Hack, E.5    Lupu, C.6    Taylor, F.B.7    Lupu, F.8
  • 11
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
    • Kawai, T. and Akira, S. (2010) The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat. Immunol., 11, 373-384.
    • (2010) Nat. Immunol. , vol.11 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 13
    • 28744443398 scopus 로고    scopus 로고
    • Dendrimers in biomedical applications-reflections on the field
    • Svenson, S. and Tomalia, D.A. (2005) Dendrimers in biomedical applications-reflections on the field. Adv. Drug Delivery Rev., 57, 2106-2129.
    • (2005) Adv. Drug Delivery Rev. , vol.57 , pp. 2106-2129
    • Svenson, S.1    Tomalia, D.A.2
  • 14
    • 0032980120 scopus 로고    scopus 로고
    • Adjunctive therapy in sepsis: A critical analysis of the clinical trial programme
    • Cohen J. (1999) Adjunctive therapy in sepsis: a critical analysis of the clinical trial programme. Br. Med. Bull., 55, 212-226.
    • (1999) Br. Med. Bull. , vol.55 , pp. 212-226
    • Cohen, J.1
  • 15
    • 0037179685 scopus 로고    scopus 로고
    • Risks and benefits of activated protein C treatment for severe sepsis
    • Warren, H.S.; Suffredini, A.F.; Eichacker, P.Q. and Munford, R.S. (2002) Risks and benefits of activated protein C treatment for severe sepsis. N. Engl. J. Med., 347, 1027-1030.
    • (2002) N. Engl. J. Med. , vol.347 , pp. 1027-1030
    • Warren, H.S.1    Suffredini, A.F.2    Eichacker, P.Q.3    Munford, R.S.4
  • 16
  • 18
    • 77955641577 scopus 로고    scopus 로고
    • Protective effects of remifentanil on septic mice
    • Zongze, Z.; Jia, Z.; Chang, C.; Kai, C. and Yanlin, W. (2010) Protective effects of remifentanil on septic mice. Mol. Biol. Rep., 37, 2803-2808.
    • (2010) Mol. Biol. Rep. , vol.37 , pp. 2803-2808
    • Zongze, Z.1    Jia, Z.2    Chang, C.3    Kai, C.4    Yanlin, W.5
  • 19
    • 81155137227 scopus 로고    scopus 로고
    • EPCK1, a Vitamin C and E Analogue, Reduces Endotoxin-Induced Systemic Inflammation in Mice
    • Shingu, C.; Hagiwara, S.; Iwasaka, H.; Matsumoto, S.; Koga, H.; Yokoi, I. and Noguchi, T. (2011) EPCK1, a Vitamin C and E Analogue, Reduces Endotoxin-Induced Systemic Inflammation in Mice. J. Surg. Res., 171, 719-725.
    • (2011) J. Surg. Res. , vol.171 , pp. 719-725
    • Shingu, C.1    Hagiwara, S.2    Iwasaka, H.3    Matsumoto, S.4    Koga, H.5    Yokoi, I.6    Noguchi, T.7
  • 21
    • 60849086453 scopus 로고    scopus 로고
    • VPAC and PAC receptors: From ligands to function
    • Dickson, L. and Finlayson, K. (2009) VPAC and PAC receptors: From ligands to function. Pharmacol. Ther., 121, 294-316.
    • (2009) Pharmacol. Ther. , vol.121 , pp. 294-316
    • Dickson, L.1    Finlayson, K.2
  • 22
    • 67650689306 scopus 로고    scopus 로고
    • Immunomodulation of innate immune responses by vasoactive intestinal peptide (VIP): Its therapeutic potential in inflammatory disease
    • Smalley, S.R.G.; Barrow, P.A. and Foster, N. (2009) Immunomodulation of innate immune responses by vasoactive intestinal peptide (VIP): its therapeutic potential in inflammatory disease. Clin. Exp. Immunol., 157, 225-234.
    • (2009) Clin. Exp. Immunol. , vol.157 , pp. 225-234
    • Smalley, S.R.G.1    Barrow, P.A.2    Foster, N.3
  • 23
    • 0035808447 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide regulated NF-NB at multiple levels
    • Delgado, M. and Ganea, D. (2001) Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide regulated NF-NB at multiple levels. J. Biol. Chem., 276, 369-380.
    • (2001) J. Biol. Chem. , vol.276 , pp. 369-380
    • Delgado, M.1    Ganea, D.2
  • 24
    • 0034500696 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide (VIP) receptor type 2 (VPAC2) is the predominant receptor expressed in human thymocytes
    • Lara-Marquez, M.L.; O'Dorisio, M.S. and Karacay, B. (2000) Vasoactive intestinal peptide (VIP) receptor type 2 (VPAC2) is the predominant receptor expressed in human thymocytes. Ann. N. Y. Acad. Sci., 921, 45-54.
    • (2000) Ann. N. Y. Acad. Sci. , vol.921 , pp. 45-54
    • Lara-Marquez, M.L.1    O'Dorisio, M.S.2    Karacay, B.3
  • 25
    • 19944429783 scopus 로고    scopus 로고
    • VIP attenuation of the severity of experimental pancreatitis is due to VPAC1 receptor-mediated inhibition of cytokine production
    • Kojima, M.; Ito, T.; Oono, T.; Hisano, T.; Igarashi, H.; Arita, Y.; Kawabe, K.; Coy, D.H.; Jensen, R.T. and Nawata, H. (2005) VIP attenuation of the severity of experimental pancreatitis is due to VPAC1 receptor-mediated inhibition of cytokine production. Pancreas, 30, 62-70.
    • (2005) Pancreas , vol.30 , pp. 62-70
    • Kojima, M.1    Ito, T.2    Oono, T.3    Hisano, T.4    Igarashi, H.5    Arita, Y.6    Kawabe, K.7    Coy, D.H.8    Jensen, R.T.9    Nawata, H.10
  • 26
    • 0033561657 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide prevent inducible nitric oxide synthase transcription in macrophages by inhibiting NF-kappa B and IFN regulatory factor 1 activation
    • Delgado, M.; Munoz-Elias, E.J.; Gomariz, R.P. and Ganea, D. (1999) Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide prevent inducible nitric oxide synthase transcription in macrophages by inhibiting NF-kappa B and IFN regulatory factor 1 activation. J. Immunol., 162, 4685-4696.
    • (1999) J. Immunol. , vol.162 , pp. 4685-4696
    • Delgado, M.1    Munoz-Elias, E.J.2    Gomariz, R.P.3    Ganea, D.4
  • 27
    • 0036079049 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) as modulators of both innate and adaptive immunity
    • Ganea, D. and Delgado, M. (2002) Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) as modulators of both innate and adaptive immunity. Crit. Rev. Oral Biol. Med., 13, 229-237.
    • (2002) Crit. Rev. Oral Biol. Med. , vol.13 , pp. 229-237
    • Ganea, D.1    Delgado, M.2
  • 28
    • 0032516760 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide inhibits IL-12 and nitric oxide production in murine macrophages
    • Xin, Z. and Sriram, S. (1998) Vasoactive intestinal peptide inhibits IL-12 and nitric oxide production in murine macrophages. J. Neuroimmunol., 89, 206-212.
    • (1998) J. Neuroimmunol. , vol.89 , pp. 206-212
    • Xin, Z.1    Sriram, S.2
  • 29
    • 0035863808 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide and pituitary adenylate cyclase activating polypeptide inhibit expression of Fas ligand in activated T lymphocytes by regulating c-Myc, NF-cB, NF-AT, and early growth factors 2/3
    • Delgado, M. and Ganea, D. (2001) Vasoactive intestinal peptide and pituitary adenylate cyclase activating polypeptide inhibit expression of Fas ligand in activated T lymphocytes by regulating c-Myc, NF-cB, NF-AT, and early growth factors 2/3. J. Immunol., 166, 1028-1040.
    • (2001) J. Immunol. , vol.166 , pp. 1028-1040
    • Delgado, M.1    Ganea, D.2
  • 30
    • 0029665857 scopus 로고    scopus 로고
    • p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A
    • Yang, X-J.; Ogyzko, V.V.; Nishikawa, J.; Howard, B.H. and Nakatani, Y. A. (1996) p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature, 382, 319-324.
    • (1996) Nature , vol.382 , pp. 319-324
    • Yang, X.-J.1    Ogyzko, V.V.2    Nishikawa, J.3    Howard, B.H.4    Nakatani, Y.A.5
  • 31
    • 12144274019 scopus 로고    scopus 로고
    • Inhibition of IFNgamma-stimulated proinflammatory cytokines by vasoactive intestinal peptide (VIP) correlates with increased survival of Salmonella enterica serovar typhimurium phoP in murine macrophages
    • Foster, N.; Hulme, S.D. and Barrow, P.A. (2005) Inhibition of IFNgamma-stimulated proinflammatory cytokines by vasoactive intestinal peptide (VIP) correlates with increased survival of Salmonella enterica serovar typhimurium phoP in murine macrophages. J. Interferon Cytokine Res., 25, 31-42.
    • (2005) J. Interferon Cytokine Res. , vol.25 , pp. 31-42
    • Foster, N.1    Hulme, S.D.2    Barrow, P.A.3
  • 32
    • 33847032094 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide (VIP) prevents killing of virulent and phoP mutant Salmonella typhimurium by inhibiting IFN-gamma stimulated NADPH oxidative pathways in murine macrophages
    • Foster, N.; Hulme, S.D. and Barrow, P.A. (2006) Vasoactive intestinal peptide (VIP) prevents killing of virulent and phoP mutant Salmonella typhimurium by inhibiting IFN-gamma stimulated NADPH oxidative pathways in murine macrophages. Cytokine, 36, 134-140.
    • (2006) Cytokine , vol.36 , pp. 134-140
    • Foster, N.1    Hulme, S.D.2    Barrow, P.A.3
  • 33
    • 0043246759 scopus 로고    scopus 로고
    • Induction of antimicrobial pathways during early-phase immune response to Salmonella spp. in murine macrophages: Gamma interferon (IFNgamma) and upregulation of IFN-gamma receptor alpha expression are required for NADPH phagocytic oxidase gp91-stimulated oxidative burst and control of virulent Salmonella spp
    • Foster, N.; Hulme, S.D. and Barrow, P.A. (2003) Induction of antimicrobial pathways during early-phase immune response to Salmonella spp. in murine macrophages: gamma interferon (IFNgamma) and upregulation of IFN-gamma receptor alpha expression are required for NADPH phagocytic oxidase gp91-stimulated oxidative burst and control of virulent Salmonella spp. Infect. Immun., 71, 4733-4741.
    • (2003) Infect. Immun. , vol.71 , pp. 4733-4741
    • Foster, N.1    Hulme, S.D.2    Barrow, P.A.3
  • 34
    • 0035863808 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide and pituitary adenylate cyclase activating polypeptide inhibit expression of Fas ligand in activated T lymphocytes by regulating c-Myc, NF-cB, NF-AT, and early growth factors 2/3
    • Delgado, M. and Ganea, D. Vasoactive intestinal peptide and pituitary adenylate cyclase activating polypeptide inhibit expression of Fas ligand in activated T lymphocytes by regulating c-Myc, NF-cB, NF-AT, and early growth factors 2/3. J. Immunol., 166, 1028-1040.
    • J. Immunol. , vol.166 , pp. 1028-1040
    • Delgado, M.1    Ganea, D.2
  • 35
    • 33644655656 scopus 로고    scopus 로고
    • VIP inhibits Porphyromonas gingivalis LPS-induced immune responses in human monocytes
    • Foster. N.; Cheetham, J.; Taylor, J.J. and Preshaw, P.M. (2005) VIP inhibits Porphyromonas gingivalis LPS-induced immune responses in human monocytes. J. Dent. Res., 84, 999-1004.
    • (2005) J. Dent. Res. , vol.84 , pp. 999-1004
    • Foster, N.1    Cheetham, J.2    Taylor, J.J.3    Preshaw, P.M.4
  • 36
    • 34548730856 scopus 로고    scopus 로고
    • VIP inhibits P. gingivalis LPS-induced IL-18 and IL-18BPa in monocytes
    • Foster, N.; Andreadou, K.; Jamieson, L.; Preshaw, P.M. and Taylor, J.J. (2007) VIP inhibits P. gingivalis LPS-induced IL-18 and IL-18BPa in monocytes. J. Dent. Res., 86, 883-887.
    • (2007) J. Dent. Res. , vol.86 , pp. 883-887
    • Foster, N.1    Andreadou, K.2    Jamieson, L.3    Preshaw, P.M.4    Taylor, J.J.5
  • 39
    • 33645862566 scopus 로고    scopus 로고
    • Jun signalling in the epidermis: From developmental defects to psoriasis and skin tumors
    • Zenz, R. and Wagner, E.F. (2006) Jun signalling in the epidermis: From developmental defects to psoriasis and skin tumors. Int. J. Biochem. Cell Biol., 38, 1043-1049.
    • (2006) Int. J. Biochem. Cell Biol. , vol.38 , pp. 1043-1049
    • Zenz, R.1    Wagner, E.F.2
  • 40
    • 0025720571 scopus 로고
    • Lipopolysaccharide-mediated transcriptional activation of the human tissue factor gene in THP-1 monocytic cells requires both activator protein 1 and nuclear factor kappa B binding sites
    • Mackman, N.; Brand, K. and Edgington, T.S. (1991) Lipopolysaccharide-mediated transcriptional activation of the human tissue factor gene in THP-1 monocytic cells requires both activator protein 1 and nuclear factor kappa B binding sites. J. Exp. Med., 174, 1517-1526.
    • (1991) J. Exp. Med. , vol.174 , pp. 1517-1526
    • Mackman, N.1    Brand, K.2    Edgington, T.S.3
  • 41
    • 0027255749 scopus 로고
    • Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide
    • Xie, Q.W.; Whisnant, R. and Nathan, C. (1993) Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide. J. Exp. Med., 177, 1779-1784.
    • (1993) J. Exp. Med. , vol.177 , pp. 1779-1784
    • Xie, Q.W.1    Whisnant, R.2    Nathan, C.3
  • 43
    • 0034597150 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide and pituitary adenylate cyclase activating polypeptide inhibit the MEKK1/MEK4/JNK signalling pathway in LPS-stimulated macrophages
    • Delgado, M. and Ganea, D. (2000) Vasoactive intestinal peptide and pituitary adenylate cyclase activating polypeptide inhibit the MEKK1/MEK4/JNK signalling pathway in LPS-stimulated macrophages. J. Neuroimmunol., 110, 97-105.
    • (2000) J. Neuroimmunol. , vol.110 , pp. 97-105
    • Delgado, M.1    Ganea, D.2
  • 44
    • 33947643643 scopus 로고    scopus 로고
    • Pivotal advance: Vasoactive intestinal peptide inhibits up-regulation of human monocyte TLR2 and TLR4 by LPS and differentiation of monocytes to macrophages
    • Foster, N.; Lea, S.R.; Preshaw, P.M. and Taylor, J.J. (2007) Pivotal advance: vasoactive intestinal peptide inhibits up-regulation of human monocyte TLR2 and TLR4 by LPS and differentiation of monocytes to macrophages. J. Leukoc. Biol., 81, 893-903.
    • (2007) J. Leukoc. Biol. , vol.81 , pp. 893-903
    • Foster, N.1    Lea, S.R.2    Preshaw, P.M.3    Taylor, J.J.4
  • 45
    • 0029889868 scopus 로고    scopus 로고
    • Expression of vasoactive intestinal peptide in lymphocytes: A possible endogenous role in the regulation of the immune system
    • Leceta, J.; Martínez, C.; Delgado, M.; Garrido, E. and Gomariz, R.P. (1996) Expression of vasoactive intestinal peptide in lymphocytes: a possible endogenous role in the regulation of the immune system. Adv. Neuroimmunol., 6, 29-36.
    • (1996) Adv. Neuroimmunol. , vol.6 , pp. 29-36
    • Leceta, J.1    Martínez, C.2    Delgado, M.3    Garrido, E.4    Gomariz, R.P.5
  • 46
    • 0035496990 scopus 로고    scopus 로고
    • TH2 lymphocytes secrete functional VIP upon antigen stimulation
    • Vassiliou, E.; Jiang, X.; Delgado, M. and Ganea, D. (2001) TH2 lymphocytes secrete functional VIP upon antigen stimulation. Arch. Physiol. Biochem., 109, 365-368.
    • (2001) Arch. Physiol. Biochem. , vol.109 , pp. 365-368
    • Vassiliou, E.1    Jiang, X.2    Delgado, M.3    Ganea, D.4
  • 47
    • 34548426906 scopus 로고    scopus 로고
    • A novel VIP signaling pathway in T cells cAMP-->protein tyrosine phosphatase (SHP-2?)-->JAK2/STAT4-->Th1 differentiation
    • Liu, L.; Yen, J.H. and Ganea D. (2007) A novel VIP signaling pathway in T cells cAMP-->protein tyrosine phosphatase (SHP-2?)-->JAK2/STAT4-->Th1 differentiation. Peptides, 28, 1814-1824.
    • (2007) Peptides , vol.28 , pp. 1814-1824
    • Liu, L.1    Yen, J.H.2    Ganea, D.3
  • 48
    • 0035497005 scopus 로고    scopus 로고
    • VIP and PACAP enhance the in vivo generation of memory TH2 cells by inhibiting peripheral deletion of antigen-specific effectors
    • Delgado, M. and Ganea, D. (2001) VIP and PACAP enhance the in vivo generation of memory TH2 cells by inhibiting peripheral deletion of antigen-specific effectors. Arch. Physiol. Biochem., 109, 372-376.
    • (2001) Arch. Physiol. Biochem. , vol.109 , pp. 372-376
    • Delgado, M.1    Ganea, D.2
  • 49
    • 6344227308 scopus 로고    scopus 로고
    • VIP/PACAP preferentially attract Th2 effectors through differential regulation of chemokine production by dendritic cells
    • Delgado, M.; Gonzalez-Rey, E. and Ganea, D. (2004) VIP/PACAP preferentially attract Th2 effectors through differential regulation of chemokine production by dendritic cells. FASEB J., 18, 1453-1455.
    • (2004) FASEB J. , vol.18 , pp. 1453-1455
    • Delgado, M.1    Gonzalez-Rey, E.2    Ganea, D.3
  • 50
    • 28844479524 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide generates CD4+CD25+ regulatory T cells in vivo
    • Delgado, M.; Chorny, A.; Gonzalez-Rey, E. and Ganea, D. (2005) Vasoactive intestinal peptide generates CD4+CD25+ regulatory T cells in vivo. J. Leukoc. Biol., 78, 1327-1338.
    • (2005) J. Leukoc. Biol. , vol.78 , pp. 1327-1338
    • Delgado, M.1    Chorny, A.2    Gonzalez-Rey, E.3    Ganea, D.4
  • 51
    • 0024578205 scopus 로고
    • Elevated VIP and plasma endotoxin in human Gram-negative septic shock
    • Brandtzaeg, P.; Øktedalen, O.; Kierulf, P. and Opstad, P.K. (1989) Elevated VIP and plasma endotoxin in human Gram-negative septic shock. Regul. Pept., 24, 37-44.
    • (1989) Regul. Pept. , vol.24 , pp. 37-44
    • Brandtzaeg, P.1    Øktedalen, O.2    Kierulf, P.3    Opstad, P.K.4
  • 54
    • 0023709456 scopus 로고
    • Release of vasoactive intestinal peptide during hyperdynamic sepsis in dogs
    • Fuortes, M.; Blank, M.A.; Scalea, T.M.; Pollock, T.W. and Jaffe, B.M. (1988) Release of vasoactive intestinal peptide during hyperdynamic sepsis in dogs. Surgery, 104, 894-898.
    • (1988) Surgery , vol.104 , pp. 894-898
    • Fuortes, M.1    Blank, M.A.2    Scalea, T.M.3    Pollock, T.W.4    Jaffe, B.M.5
  • 55
    • 0002759047 scopus 로고
    • Role of cytokines in septic shock and shock-related syndromes
    • Blackwell Science, Cambridge
    • Montegut, W.; Lowry, S.F. and Moldawer, L.L. (1995) Role of cytokines in septic shock and shock-related syndromes. B. B. Aggerwal, and R. K. Puri, eds. Human Cytokines: Their Role in Disease and Therapy 381. Blackwell Science, Cambridge.
    • (1995) Human Cytokines: Their Role in Disease and Therapy , vol.381
    • Montegut, W.1    Lowry, S.F.2    Moldawer, L.L.3
  • 57
    • 0033555396 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activation polypeptide (PACAP) protect mice from lethal endotoxemia through the inhibition of TNF-alpha and IL-6
    • Delgado, M.; Martinez, C.; Pozo, D.; Calvo, J.R.; Leceta, J.; Ganea, D. and Gomariz, R.P. (1999) Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activation polypeptide (PACAP) protect mice from lethal endotoxemia through the inhibition of TNF-alpha and IL-6. J. Immunol., 162, 1200-1205.
    • (1999) J. Immunol. , vol.162 , pp. 1200-1205
    • Delgado, M.1    Martinez, C.2    Pozo, D.3    Calvo, J.R.4    Leceta, J.5    Ganea, D.6    Gomariz, R.P.7
  • 58
    • 0033555396 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activation polypeptide (PACAP) protect mice from lethal endotoxemia through the inhibition of TNF-alpha and IL-6
    • Delgado, M.; Martinez, C.; Pozo, D.; Calvo, J.R.; Leceta, J.; Ganea, D. and Gomariz, R.P. (1999) Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activation polypeptide (PACAP) protect mice from lethal endotoxemia through the inhibition of TNF-alpha and IL-6. J. Immunol., 162, 1200-1205.
    • (1999) J. Immunol. , vol.162 , pp. 1200-1205
    • Delgado, M.1    Martinez, C.2    Pozo, D.3    Calvo, J.R.4    Leceta, J.5    Ganea, D.6    Gomariz, R.P.7
  • 59
    • 43449087928 scopus 로고    scopus 로고
    • Neuropeptides rescue mice from lethal sepsis by down-regulating secretion of the late-acting inflammatory mediator high mobility group box 1
    • Chorny, A. and Delgado, M. (2008) Neuropeptides rescue mice from lethal sepsis by down-regulating secretion of the late-acting inflammatory mediator high mobility group box 1. Am. J. Pathol. 172, 1297-1307.
    • (2008) Am. J. Pathol , vol.172 , pp. 1297-1307
    • Chorny, A.1    Delgado, M.2
  • 60
    • 46749101760 scopus 로고    scopus 로고
    • Protective effects of vasoactive intestinal peptide on septic shock rats
    • Qiu, J.F.; Zhang, Z.Q.; Chen, W. and Wu, Z.Y. (2007) Protective effects of vasoactive intestinal peptide on septic shock rats. Zhonghua Wai Ke Za Zhi, 45, 196-199.
    • (2007) Zhonghua Wai Ke Za Zhi , vol.45 , pp. 196-199
    • Qiu, J.F.1    Zhang, Z.Q.2    Chen, W.3    Wu, Z.Y.4
  • 61
    • 0037269112 scopus 로고    scopus 로고
    • Interactions of VIP, secretin and PACAP (1-38) with phospholipids: A biological paradox revisited
    • Krishnadas, A.; Onyüksel, H. and Rubinstein, I. (2003) Interactions of VIP, secretin and PACAP (1-38) with phospholipids: a biological paradox revisited. Curr. Pharm. Des., 9, 1005-1012.
    • (2003) Curr. Pharm. Des. , vol.9 , pp. 1005-1012
    • Krishnadas, A.1    Onyüksel, H.2    Rubinstein, I.3
  • 62
    • 23144449186 scopus 로고    scopus 로고
    • Human VIP-alpha: An emerging biologic response modifier to treat primary pulmonary hypertension
    • Rubinstein, I. (2005) Human VIP-alpha: an emerging biologic response modifier to treat primary pulmonary hypertension. Expert. Rev. Cardiovasc. Ther., 3, 565-569.
    • (2005) Expert. Rev. Cardiovasc. Ther. , vol.3 , pp. 565-569
    • Rubinstein, I.1
  • 63
  • 64
    • 42749089385 scopus 로고    scopus 로고
    • Inhalable liposomal formulation for vasoactive intestinal peptide
    • Hajos, F.; Stark, B.; Hensler, S.; Prassl, R. and Mosgoeller, W. (2008) Inhalable liposomal formulation for vasoactive intestinal peptide. Int. J. Pharm., 357, 286-294.
    • (2008) Int. J. Pharm. , vol.357 , pp. 286-294
    • Hajos, F.1    Stark, B.2    Hensler, S.3    Prassl, R.4    Mosgoeller, W.5
  • 65
    • 9244247602 scopus 로고    scopus 로고
    • Exploiting receptor biology for vaccination with biodegradable particulates
    • Foster, N. and Hirst, B.H. (2005) Exploiting receptor biology for vaccination with biodegradable particulates. Adv. Drug Deliv. Rev., 57, 431-450.
    • (2005) Adv. Drug Deliv. Rev. , vol.57 , pp. 431-450
    • Foster, N.1    Hirst, B.H.2
  • 66
    • 0011736531 scopus 로고
    • Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent
    • Fields, P.I.; Swanson, R.V.; Haidaris, C.G. and Heffron, F. (1986) Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent. Proc. Natl. Acad. Sci. USA, 83, 5189-5193.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 5189-5193
    • Fields, P.I.1    Swanson, R.V.2    Haidaris, C.G.3    Heffron, F.4
  • 67
    • 0025318414 scopus 로고
    • Constitutive expression of the phoP regulon attenuates Salmonella virulence and survival within macrophages
    • Miller, S. I. and Mekalanos, J.J. (1990) Constitutive expression of the phoP regulon attenuates Salmonella virulence and survival within macrophages. J. Bacteriol., 172, 2485-2490.
    • (1990) J. Bacteriol. , vol.172 , pp. 2485-2490
    • Miller, S.I.1    Mekalanos, J.J.2
  • 68
    • 0025190896 scopus 로고
    • Salmonella virulence: New clues to intramacrophage survival
    • Groisman, E. A. and Saier, M.H. (1990) Salmonella virulence: new clues to intramacrophage survival. Trends Biochem. Sci., 15, 30-33.
    • (1990) Trends Biochem. Sci. , vol.15 , pp. 30-33
    • Groisman, E.A.1    Saier, M.H.2


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