A novel antimicrobial peptide derived from modified N-terminal domain of bovine lactoferrin: Design, synthesis, activity against multidrug-resistant bacteria and Candida

Biochimica et Biophysica Acta - Biomembranes

Volumn 1828, Issue 2, 2013, Pages 677-686

  Mishra, Biswajit ^a   Leishangthem, Geeta Devi ^a   Gill, Kamaldeep ^a   Singh, Abhay K ^a   Das, Swagata ^a   Singh, Kusum ^a   Xess, Immaculata ^a   Dinda, Amit ^a   Kapil, Arti ^a   Patro, Ishan K ^b   Dey, Sharmistha ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^b JIWAJI UNIVERSITY   (India)

Author keywords

Anti inflammatory; Antimicrobial peptide; Cyclooxygenase; Extended spectrum beta lactamase; Lactoferrin; Surface plasmon resonance

Indexed keywords

ALANYLPHENYLALANYLARGINYLLYSYLGLUTAMINYLLEUCYLLYSYLTRYPTOPHAN; ALANYLPROLYLARGINYLARGINYLGLUTAMINYLLEUCYLLYSYLTRYPTOPHAN; ALANYLPROLYLARGINYLLYSYLASPARAGINYLLEUCYLLYSYLTRYPTOPHAN; ALANYLPROLYLARGINYLLYSYLASPARAGINYLVALYLARGINYLPHENYLALANINE; ALANYLPROLYLARGINYLLYSYLASPARAGINYLVALYLARGINYLTRYPTOPHAN; ALANYLPROLYLARGINYLLYSYLASPARAGINYLVALYLLYSYLTRYPTOPHAN; ALANYLPROLYLARGINYLLYSYLGLUTAMINYLLEUCYLLYSYLTRYPTOPHAN; ALANYLPROLYLLYSYLLYSYLGLUTAMINYLLEUCYLLYSYLTRYPTOPHAN; COLISTIN; CYCLOOXYGENASE 2; EXTENDED SPECTRUM BETA LACTAMASE; FLUCONAZOLE; GENTAMICIN; LACTOFERRIN; LEUCYLPHENYLALANYLARGINYLLYSYLGLUTAMINYLLEUCYLLYSYLTRYPTOPHAN; LIPID A; LIPOPOLYSACCHARIDE; POLYPEPTIDE ANTIBIOTIC AGENT; PROPIDIUM IODIDE; TRYPTOPHANYLPHENYLALANYLARGINYLLYSYLGLUTAMINYLLEUCYLLYSYLTRYPTOPHAN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIFUNGAL ACTIVITY; ANTIFUNGAL RESISTANCE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATION; CANDIDA; CELL PERMEABILIZATION; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; DRUG TARGETING; ENZYME INHIBITION; FLOW CYTOMETRY; FUNGAL CELL; FUNGAL STRAIN; GRAM NEGATIVE BACTERIUM; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIFUNGAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BETA-LACTAMASES; CANDIDA; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; ERYTHROCYTES; HEMOLYSIS; HUMANS; KINETICS; LACTOFERRIN; LIPOPOLYSACCHARIDES; MICROBIAL SENSITIVITY TESTS; MICROSCOPY, ELECTRON; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; SURFACE PLASMON RESONANCE; TIME FACTORS;

BOVINAE; CANDIDA; NEGIBACTERIA;

EID: 84870203850     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2012.09.021     Document Type: Article

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