Fungicidal activity of human lactoferrin-derived peptides based on the antimicrobial αβ region

International Journal of Antimicrobial Agents

Volumn 37, Issue 1, 2011, Pages 51-57

  Kondori, N ^a   Baltzer, L ^b   Dolphin, G T ^c   Mattsby Baltzer, I ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Candida albicans; Fungicidal activity; Lactoferricin; Peptide

Indexed keywords

AMPHOTERICIN B; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; FLUCONAZOLE; FLUCYTOSINE; HL10 PEPTIDE; HLBD1 PEPTIDE; HLOPT2 PEPTIDE; LACTOFERRIN; PEPTIDE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; CANDIDA ALBICANS; CANDIDA GLABRATA; CANDIDA KRUSEI; CANDIDA PARAPSILOSIS; CANDIDIASIS; COLONY FORMING UNIT; CONFERENCE PAPER; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG SYNTHESIS; FUNGAL STRAIN; FUNGICIDAL ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TIME; KLUYVEROMYCES MARXIANUS; MEMBRANE PERMEABILITY; MINIMUM INHIBITORY CONCENTRATION; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN INFECTION; SPECIES COMPARISON; YEAST CELL;

ANIMALS; ANTI-INFECTIVE AGENTS; CANDIDA; CANDIDIASIS; CRYPTOCOCCUS NEOFORMANS; DERMATOMYCOSES; DISEASE MODELS, ANIMAL; HUMANS; LACTOFERRIN; MICE; MICROBIAL VIABILITY; TREATMENT OUTCOME;

EID: 78650270707     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2010.08.020     Document Type: Conference Paper

References (26)

1. K.A. Brogden, M. Ackermann, P.B. McCray Jr., and B.F. Tack Antimicrobial peptides in animals and their role in host defences Int J Antimicrob Agents 22 2003 465 478
2. J.H. Nuijens, P.H. van Berkel, and F.L. Schanbacher Structure and biological actions of lactoferrin J Mammary Gland Biol Neoplasia 1 1996 285 295
3. M. Tollin, P. Bergman, T. Svenberg, H. Jornvall, G.H. Gudmundsson, and B. Agerberth Antimicrobial peptides in the first line defence of human colon mucosa Peptides 24 2003 523 530
4. W. Bellamy, M. Takase, K. Yamauchi, H. Wakabayashi, K. Kawase, and M. Tomita Identification of the bactericidal domain of lactoferrin Biochim Biophys Acta 1121 1992 130 136
5. K. Yamauchi, M. Tomita, T.J. Giehl, and R.T. Ellison 3rd Antibacterial activity of lactoferrin and a pepsin-derived lactoferrin peptide fragment Infect Immun 61 1993 719 728
6. E.N. Baker, and H.M. Baker Molecular structure, binding properties and dynamics of lactoferrin Cell Mol Life Sci 62 2005 2531 2539
7. B.F. Anderson, H.M. Baker, E.J. Dodson, G.E. Norris, S.V. Rumball, and J.M. Waters Structure of human lactoferrin at 3.2- resolution Proc Natl Acad Sci U S A 84 1987 1769 1773
8. E.W. Odell, R. Sarra, M. Foxworthy, D.S. Chapple, and R.W. Evans Antibacterial activity of peptides homologous to a loop region in human lactoferrin FEBS Lett 382 1996 175 178
9. D.S. Chapple, D.J. Mason, C.L. Joannou, E.W. Odell, V. Gant, and R.W. Evans Structure-function relationship of antibacterial synthetic peptides homologous to a helical surface region on human lactoferrin against Escherichia coli serotype O111 Infect Immun 66 1998 2434 2440
10. A. Lupetti, A. Paulusma-Annema, M.M. Welling, S. Senesi, J.T. van Dissel, and P.H. Nibbering Candidacidal activities of human lactoferrin peptides derived from the N terminus Antimicrob Agents Chemother 44 2000 3257 3263
11. L.A. Hversen, N. Kondori, L. Baltzer, L.A. Hanson, G.T. Dolphin, K. Dunér, and I. Mattsby-Baltzer Structure-microbicidal activity relationship of synthetic fragments derived from the antibacterial α-helix of human lactoferrin Antimicrob Agents Chemother 54 2010 418 425
12. F.S. Clark, T. Parkinson, C.A. Hitchcock, and N.A. Gow Correlation between rhodamine 123 accumulation and azole sensitivity in Candida species: possible role for drug efflux in drug resistance Antimicrob Agents Chemother 40 1996 419 425
13. P.L. Friedman, and M.H. Ellisman Enhanced visualization of peripheral nerve and sensory receptors in the scanning electron microscope using cryofracture and osmium-thiocarbohydrazide-osmium impregnation J Neurocytol 10 1981 111 131
14. P.G. Sohnle, and B.L. Hahn Epidermal proliferation and the neutrophilic infiltrates of experimental cutaneous candidiasis in mice Arch Dermatol Res 281 1989 279 283
15. E.J. Helmerhorst, C. Venuleo, D. Sanglard, and F.G. Oppenheim Roles of cellular respiration, CgCDR1, and CgCDR2 in Candida glabrata resistance to histatin 5 Antimicrob Agents Chemother 50 2006 1100 1103
16. H.N. Hunter, A.R. Demcoe, H. Jenssen, T.J. Gutteberg, and H.J. Vogel Human lactoferricin is partially folded in aqueous solution and is better stabilized in a membrane mimetic solvent Antimicrob Agents Chemother 49 2005 3387 3395
17. P. Gerhardt, and J.A. Judge Porosity of isolated cell walls of Saccharomyces cerevisiae and Bacillus megaterium J Bacteriol 87 1964 945 951
18. W. Bellamy, H. Wakabayashi, M. Takase, K. Kawase, S. Shimamura, and M. Tomita Killing of Candida albicans by lactoferricin B, a potent antimicrobial peptide derived from the N-terminal region of bovine lactoferrin Med Microbiol Immunol (Berl) 182 1993 97 105
19. M. Viejo-Diaz, M.T. Andres, and J.F. Fierro Different anti-Candida activities of two human lactoferrin-derived peptides, Lfpep and kaliocin-1 Antimicrob Agents Chemother 49 2005 2583 2588
20. T. Okamoto, T. Tanida, B. Wei, E. Ueta, T. Yamamoto, and T. Osaki Regulation of fungal infection by a combination of amphotericin B and peptide 2, a lactoferrin peptide that activates neutrophils Clin Diagn Lab Immunol 11 2004 1111 1119
21. S. Vylkova, X.S. Li, J.C. Berner, and M. Edgerton Distinct antifungal mechanisms: β-defensins require Candida albicans Ssa1 protein, while Trk1p mediates activity of cysteine-free cationic peptides Antimicrob Agents Chemother 50 2006 324 331
22. E.J. Helmerhorst, C. Venuleo, A. Beri, and F.G. Oppenheim Candida glabrata is unusual with respect to its resistance to cationic antifungal proteins Yeast 22 2005 705 714
23. J.E. Bennett, K. Izumikawa, and K.A. Marr Mechanism of increased fluconazole resistance in Candida glabrata during prophylaxis Antimicrob Agents Chemother 48 2004 1773 1777
24. J.P. Vermitsky, and T.D. Edlind Azole resistance in Candida glabrata: coordinate upregulation of multidrug transporters and evidence for a Pdr1-like transcription factor Antimicrob Agents Chemother 48 2004 3773 3781
25. D.A. Devine, and R.E. Hancock Cationic peptides: distribution and mechanisms of resistance Curr Pharm Des 8 2002 703 714
26. L.A. Haversen, I. Engberg, L. Baltzer, G. Dolphin, L.A. Hanson, and I. Mattsby-Baltzer Human lactoferrin and peptides derived from a surface-exposed helical region reduce experimental Escherichia coli urinary tract infection in mice Infect Immun 68 2000 5816 5823