Aspidin PB, a phloroglucinol derivative, induces apoptosis in human hepatocarcinoma HepG2 cells by modulating PI3K/Akt/GSK3β pathway

Chemico-Biological Interactions

Volumn 201, Issue 1-3, 2013, Pages 1-8

  Sun, Yao ^a   Gao, Chang ^b   Luo, Meng ^a   Wang, Wei ^a   Gu, Chengbo ^a   Zu, Yuangang ^a   Li, Ji ^a   Efferth, Thomas ^c   Fu, Yujie ^a  

^a NORTHEAST FORESTRY UNIVERSITY   (China)

^b PEKING UNIVERSITY   (China)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Apoptosis; Aspidin PB; HepG2; PI3K Akt GSK3

Indexed keywords

ASPIDIN PB; GLYCOGEN SYNTHASE KINASE 3BETA; PHLOROGLUCINOL DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; WORTMANNIN;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CELL STRAIN HEPG2; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; GENE; HUMAN; HUMAN CELL; IC 50; LIVER CELL CARCINOMA; MITOCHONDRIAL MEMBRANE POTENTIAL; NONSTEROIDAL ANTI INFLAMMATORY ACTIVATED GENE 1; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

ANDROSTADIENES; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; FLOW CYTOMETRY; GLYCOGEN SYNTHASE KINASE 3; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, CONFOCAL; PHLOROGLUCINOL; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

DRYOPTERIS FRAGRANS;

EID: 84870194182     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2012.11.005     Document Type: Article

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