Bothrops leucurus venom induces nephrotoxicity in the isolated perfused kidney and cultured renal tubular epithelia

Toxicon

Volumn 61, Issue 1, 2013, Pages 38-46

  de Morais, Isabel Cristina Oliveira ^a   Torres, Alba Fabíola Costa ^a   Pereira, Gustavo José da Silva ^b   Pereira, Ticiana Praciano ^a   Pessoa Bezerra de Menezes, Ramon Róseo de Paula ^a   Mello, Clarissa Perdigão ^a   Coelho Jorge, Antonio Rafael ^a   Bindá, Alexandre Havt ^a   Toyama, Marcos Hikari ^c   Monteiro, Helena Serra Azul ^a   Smaili, Soraya Soubhi ^b   Martins, Alice Maria Costa ^a  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Bothrops leucurus; Nephrotoxicity; Renal tubular epithelia

Indexed keywords

BOTHROPS LEUCURUS VENOM; CALCIUM ION; CASPASE 3; CASPASE 8; SNAKE VENOM; UNCLASSIFIED DRUG;

ACUTE KIDNEY FAILURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BOTHROPS; BOTHROPS LEUCURUS; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY TEST; GENE EXPRESSION; GLOMERULUS FILTRATION RATE; IC 50; KIDNEY PERFUSION; KIDNEY TUBULE CELL; KIDNEY VASCULAR RESISTANCE; MALE; MICTURITION; MITOCHONDRIAL MEMBRANE POTENTIAL; NEPHROTOXICITY; NONHUMAN; PERFUSION PRESSURE; PRIORITY JOURNAL; RAT; SODIUM TRANSPORT;

ANIMALS; ANNEXIN A5; APOPTOSIS REGULATORY PROTEINS; BOTHROPS; CALCIUM; CELL SURVIVAL; CELLS, CULTURED; COLORING AGENTS; CROTALID VENOMS; DOGS; EPITHELIAL CELLS; EPITHELIUM; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; GENE EXPRESSION; KIDNEY DISEASES; KIDNEY TUBULES; MALE; ORGAN CULTURE TECHNIQUES; PROPIDIUM; RATS;

BOTHROPS; BOTHROPS LEUCURUS;

EID: 84870170327     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2012.10.005     Document Type: Article

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