Renal kinetics of Bothrops alternatus (Urutu) snake venom in rats

Toxicon

Volumn 55, Issue 2-3, 2010, Pages 470-480

  Mello, Sueli M ^a   Linardi, Alessandra ^a,b   Rennó, André L ^a   Tarsitano, Christiane A B ^a   Pereira, Elionai M ^a   Hyslop, Stephen ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b FACULDADE DE CIÊNCIAS MÉDICAS DA SANTA CASA DE SÃO PAULO   (Brazil)

Author keywords

Acute renal failure; Bothrops; Elimination; ELISA; Envenoming; Immunohistochemistry; Nephrotoxicity; Venom pharmacokinetics

Indexed keywords

BILIRUBIN; CREATININE; GLUCOSE; KETONE; NITRITE; SNAKE VENOM; UROBILINOGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CREATININE CLEARANCE; ENVENOMATION; GLUCOSE URINE LEVEL; KIDNEY PARENCHYMA; LEUKOCYTE; MALE; NEPHROTOXICITY; NONHUMAN; OCCULT BLOOD; OLIGURIA; PRIORITY JOURNAL; PROTEINURIA; RAT; RELATIVE DENSITY; SNAKE; TOXICOKINETICS; URINE ACIDIFICATION; URINE PH; URINE VOLUME;

ANIMALS; ANTIVENINS; BOTHROPS; CREATININE; CROTALID VENOMS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; INDICATORS AND REAGENTS; KIDNEY; KIDNEY FAILURE, ACUTE; MALE; RATS; RATS, WISTAR;

BOTHROPS; BOTHROPS ALTERNATUS; RATTUS; RATTUS NORVEGICUS;

EID: 73049099809     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2009.09.018     Document Type: Article

References (76)

1. Amaral C.F.S., Da Silva O.A., Godoy P., and Miranda D. Renal cortical necrosis following Bothrops jararaca and Bothrops jararacussu snake bite. Toxicon 23 (1985) 877-885
2. Audebert F., Grosselet O., Sabouraud A., and Bon C. Quantitation of venom antigens from European vipers in human serum or urine by ELISA. J. Anal. Toxicol. 17 (1993) 236-240
3. Audebert F., Urtizberea M., Sabouraud A., Scherrmann J.M., and Bon C. Pharmacokinetics of Vipera aspis venom after experimental envenomation in rabbits. J. Pharmacol. Exp. Ther. 268 (1994) 1512-1517
4. Aung W., Kyaw A., Win T., Kyaw K.P.P., Hla B., and Hlaing T.T. Urinary NAG as an early indicator of renal damage in Russelĺs viper bite envenomation. Trans. R. Soc. Trop. Med. Hyg. 90 (1996) 169-172
5. Aung W., Kyaw A., Win T., Kyaw K.P.P., Hla B., and Hlaing T.T. Isozyme profile of urinary NAG in Russelĺs viper bite patients with renal damage. Clin. Chim. Acta 264 (1997) 251-254
6. Azevedo-Marques M.M., Cupo P., Coimbra T.M., Hering S.E., Rossi M.A., and Laure C.J. Myonecrosis, myoglobinuria and acute renal failure induced by South American rattlesnake (Crotalus durissus terrificus) envenomation in Brazil. Toxicon 23 (1985) 631-636
7. Bárbaro K.C. Utilização da técnica de ELISA no estudo do envenenamento por animais peçonhentos. In: Cardoso J.L.C., França F.O.S., Wen F.H., Málaque C.M.S., and Haddad Jr. V. (Eds). Animais Peçonhentos no Brasil: Biologia, Clínica e Terapêutica dos Acidentes (2003), Sarvier/FAPESP, São Paulo 356-363
8. Barbosa P.S.F., Havt A., Facó P.E.G., Sousa T.M., Bezerra I.S.A.M., Fonteles M.C., Toyama M.H., Marangoni S., Novello J.C., and Monteiro H.S.A. Renal toxicity of Bothrops moojeni snake venom and its main myotoxins. Toxicon 40 (2002) 1427-1435
9. Barbosa P.S.F., Martins A.M.C., Alves R.S., Amora D.N., Martins R.D., Toyama M.H., Havt A., Nascimento N.R.F., Rocha V.L.C., Menezes D.B., Fonteles M.C., and Monteiro H.S.A. The role of indomethacin and tezosentan on renal effects induced by Bothrops moojeni Lys49 myotoxin I. Toxicon 47 (2006) 831-837
10. Barbosa P.S.F., Martins A.M.C., Havt A., Toyama D.O., Evangelista J.S.A.M., Ferreira D.P.P., Joazeiro P.P., Beriam L.O.S., Toyama M.H., Fonteles M.C., and Monteiro H.S.A. Renal and antibacterial effects induced by myotoxin I and II isolated from Bothrops jararacussu venom. Toxicon 46 (2005) 376-386
11. Barral-Netto M., Schriefer A., Vinhas V., and Almeida A.R. Enzyme-linked immunosorbent assay for the detection of Bothrops jararaca venom. Toxicon 28 (1990) 1053-1061
12. Boer-Lima P.A., Gontijo J.A., and Cruz-Höfling M.A. Histologic and functional renal alterations caused by Bothrops moojeni snake venom in rats. Am. J. Trop. Med. Hyg. 61 (1999) 698-706
13. Boer-Lima P.A., Gontijo J.A., and Cruz-Höfling M.A. Bothrops moojeni snake venom-induced glomeruli changes in rat. Am. J. Trop. Med. Hyg. 67 (2002) 217-222
14. 2 isolated from Bothrops insularis venom. Toxicon 51 (2008) 181-190
15. Braga M.D.M., Martins A.M.C., Amora D.N., de Menezes D.B., Toyama M.H., Toyama D.O., Marangoni S., Alves C.D., Barbosa P.S.F., Alves R.S., Fonteles M.C., and Monteiro H.S.A. Purification and biological effects of l-amino acid oxidase isolated from Bothrops insularis venom. Toxicon 51 (2008) 199-207
16. Braga M.D.M., Martins A.M.C., Amora D.N., de Menezes D.B., Toyama M.H., Toyama D.O., Marangoni S., Barbosa P.S.F., Alves R.S., Fonteles M.C., and Monteiro H.S.A. Purification and biological effects of C-type lectin isolated from Bothrops insularis venom. Toxicon 47 (2006) 859-867
17. Braga M.D.M., Martins A.M.C., de Menezes D.B., Barbosa P.S.F., Evangelista J.S.A.M., Toyama M.H., Toyama D.O., Fonteles M.C., and Monteiro H.S.A. Purification and biological activity of the thrombin-like substance isolated from Bothrops insularis venom. Toxicon 49 (2007) 329-338
18. Burdmann E.A., Woronik V., Prado E.B., Abdulkader R.C., Saldanha L.B., Barreto O.C., and Marcondes M. Snakebite-induced acute renal failure: an experimental model. Am. J. Trop. Med. Hyg. 48 (1993) 82-88
19. 2. Toxicon 37 (1999) 771-782
20. Cardoso D.F., Yamaguchi I.K., and Moura da Silva A.M. Produção de soros antitoxinas e perspectivas de modernização por técnicas de biologia molecular. In: Cardoso J.L.C., França F.O.S., Wen F.H., Málaque C.M.S., and Haddad Jr. V. (Eds). Animais Peçonhentos do Brasil. Biologia, Clínica e Terapêutica dos Acidentes (2003), Sarvier/FAPESP, São Paulo 367-379
21. Castro I., Burdmann E.A., Seguro A.C., and Yu L. Bothrops venom induces direct renal tubular injury: role for lipid peroxidation and prevention by antivenom. Toxicon 43 (2004) 833-839
22. Catty D., and Raykundalia C. ELISA and related enzyme immunoassays. In: Catty D. (Ed). Antibodies - a Practical Approach vol. II (1989), IRL Press, Oxford, England 97-154
23. Chávez-Olórtegui C., Lopes C.S., Cordeiro F.D., Granier C., and Diniz C.R. An enzyme-linked immunosorbent assay (ELISA) that discriminates between Bothrops atrox and Lachesis muta muta venoms. Toxicon 31 (1993) 417-425
24. Chávez-Olórtegui C., Penaforte C.L., Silva R.R., Ferreira A.P., Rezende N.A., Amaral C.F.S., and Diniz C.R. An enzyme-linked immunosorbent assay (ELISA) that discriminates between the venoms of Brazilian Bothrops species and Crotalus durissus. Toxicon 35 (1997) 253-260
25. Chippaux J.P., and Goyffon M. Venoms, antivenoms and immunotherapy. Toxicon 36 (1998) 823-846
26. Collares-Buzato C.B., Le Sueur L.P., and Cruz-Höfling M.A. Impairment of the cell-to-matrix adhesion and cytotoxicity induced by Bothrops moojeni snake venom in cultured renal tubular epithelia. Toxicol. Appl. Pharmacol. 181 (2002) 124-132
27. Domingos M.O., Takehara H.A., Laing G., Snowden K.F., Sells P.G., Mota I., and Theakston R.D.G. Detection and neutralization of B. jararaca venom in mice. Braz. J. Med. Biol. Res. 27 (1994) 2613-2622
28. Escalante T., Núñez J., Moura da Silva A.M., Rucavado A., Theakston R.D., and Gutiérrez J.M. Pulmonary hemorrhage induced by jararhagin, a metalloproteinase from Bothrops jararaca snake venom. Toxicol. Appl. Pharmacol. 193 (2003) 17-28
29. França F.O.S., and Málaque C.M.S. Acidente botrópico. In: Cardoso J.L.C., França F.O.S., Wen F.H., Málaque C.M.S., and Haddad Jr. V. (Eds). Animais Peçonhentos do Brasil. Biologia, Clínica e Terapêutica dos Acidentes (2003), Sarvier/FAPESP, São Paulo 72-86
30. 2, MiPLA-1, from Micropechis ikaheka venom. Arch. Biochem. Biophys. 369 (1999) 181-192
31. Gay C.C., Maruñak S.L., Teibler P., Ruiz R., Acosta de Pérez O.C., and Leiva L.C. Systemic alterations induced by a Bothrops alternatus hemorrhagic metalloproteinase (baltergin) in mice. Toxicon 53 (2009) 53-59
32. Guo M.P., Wang Q.C., and Liu G.F. Pharmacokinetics of cytotoxin from Chinese cobra (Naja naja atra) venom. Toxicon 31 (1993) 339-343
33. Gutiérrez J.M., Escalante T., and Rucavado A. Experimental pathophysiology of systemic alterations induced by Bothrops asper snake venom. Toxicon 54 (2009) 976-987
34. Gutiérrez J.M., Leon G., and Lomonte B. Pharmacokinetic-pharmacodynamic relationships of immunoglobulin therapy for envenomation. Clin. Pharm. 42 (2003) 721-741
35. Gutiérrez J.M., Lomonte B., Leon G., Rucavado A., Chaves F., and Angulo Y. Trends in snakebite envenomation therapy: scientific, technological and public health considerations. Curr. Pharm. Des. 13 (2007) 2935-2950
36. Han K.E., Than T., Lwin M., Swe T.N., and Pe T. Urinary fibrin(-ogen) degradation products in Russell's viper (Daboia russelii siamensis) bite victims. Southeast Asian J. Trop. Med. Public Health 24 (1993) 198-201
37. Hanvivatvong O., Phanuphak P., Lowcharoenkul C., Benyajati C., and Sakulramrung R. Serum and urine levels of cobra venom in non-antivenin treated patients. In: Gopalakrishnakone P., and Tan C.K. (Eds). Progress in Venom and Toxin Research. Proceedings of the First Asia-Pacific Congress on Animal, Plant and Microbial Toxins (1987), National University of Singapore, Singapore 69-75
38. 2 and PAF blockers. Toxicon 39 (2001) 1841-1846
39. Havt A., Toyama M.H., Nascimento N.R.F., Toyama D.O., Nobre A.C.L., Martins A.M.C., Barbosa P.S.F., Novello J.C., Boschero A.C., Carneiro E.M., Fonteles M.C., and Monteiro H.S.A. A new C-type animal lectin isolated from Bothrops pirajai is responsible for the snake venom major effects in the isolated kidney. Int. J. Biochem. Cell Biol. 37 (2005) 130-141
40. Heneine L.G.D., and Catty D. Species-specific detection of venom antigens from snakes of the Bothrops and Lachesis genera. Toxicon 31 (1993) 591-603
41. Heneine L.G.D., Catty D., and Theakston R.D.G. Development of a species-specific ELISA for Brazilian pit-viper venoms. Braz. J. Med. Biol. Res. 23 (1990) 585-588
42. Ho M., Warrell D.A., Looareesuwan S., Phillips R.E., Chanthavanich P., Karbwang J., Supanaranond W., Viravan C., Hutton R.A., and Vejcho S. Clinical significance of venom antigen levels in patients envenomed by the Malayan pit viper (Calloselasma rhodostoma). Am. J. Trop. Med. Hyg. 35 (1986) 579-587
43. Ho M., Warrell M.J., Warrell D.A., Bidwell D., and Voller A. A critical reappraisal of the use of enzyme-linked immunosorbent assays in the study of snakebite. Toxicon 24 (1986) 211-221
44. Ismail M., and Abd-Elsalam M.A. Are the toxicological effects of scorpion envenomation related to tissue venom concentration?. Toxicon 26 (1988) 233-256
45. 2 and F(ab) of the antivenin. Toxicon 36 (1998) 93-114
46. 125I-labelled venom from the scorpion Androctonus amoreuxi (Aud. and Sav. Toxicon 18 (1980) 301-308
47. Ismail M., Aly M.H.M., Abd-Elsalam M.A., and Morad A.M. A three-compartment open pharmacokinetic model can explain variable toxicities of cobra venoms and their alpha toxins. Toxicon 34 (1996) 1011-1026
48. 125I labelled scorpion (Leiurus quinquestriatus H & E) venom in rat tissues. Toxicon 12 (1974) 209-211
49. Khin Ohn Lwin, Aye Aye Myint, Tun Pe, Theingie Nwe, and Min Naing. Russell's viper venom levels in serum of snakebite victims in Burma. Trans. R. Soc. Trop. Med. Hyg. 78 (1984) 165-168
50. Koscinczuk P., Borda J.T., Maruñak S., Acosta de Perez O., and de Coppo N.M. Daño renal em ratas inducido por veneno de Bothrops neuwiedi diporus de Argentina. Medicina (Buenos Aires) 64 (2004) 320-324
51. 4. Nature 227 (1970) 680-685
52. Leite F. Validação em Análise Química. third ed. (1998), Editora Átomo, Campinas
53. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193 (1951) 265-275
54. Maung-Maung-Thwin, Khin-Mee-Mee, Mi-Mi-Kyin, and Thein-Than. Kinetics of envenomation with Russell's viper (Vipera russelli) venom and of antivenom use in mice. Toxicon 26 (1988) 373-378
55. Mebs D. Pharmacology of reptilian venoms. In: Gans C., and Gans K.A. (Eds). Biology of the Reptilia. Physiology vol. 8B (1978), Academic Press, London 437-560
56. Meier J., Adler C., and Weiss N. Determination of batroxobin levels in the plasma of guinea pigs after epicutaneous and intravenous application. Toxicon 26 (1988) 964-966
57. Moreno E., and Gutiérrez J.M. Body distribution of Bothrops asper (terciopelo) snake venom myotoxin and its relationship to pathological changes. Toxicon 26 (1988) 403-409
58. Nakamura M., Kinjoh K., Miyagi C., Oka U., Sunagawa M., Yamashita S., and Kosugi T. Pharmacokinetics of habutobin in rabbits. Toxicon 33 (1995) 1201-1306
59. Nascimento J.M., Franchi Jr. G.C., Nowill A.E., Collares-Buzato C.B., and Hyslop S. Cytoskeletal rearrangement and cell death induced by Bothrops alternatus snake venom in cultured Madin-Darby canine kidney cells. Biochem. Cell Biol. 85 (2007) 591-605
60. Phillips R.E., Theakston R.D., Warrell D.A., Galigedara Y., Abeysekera D.T., Dissanayaka P., Hutton R.A., and Aloysius D.J. Paralysis, rhabdomyolysis and haemolysis caused by bites of Russell's viper (Vipera russelli pulchella) in Sri Lanka: failure of Indian (Haffkine) antivenom. Q. J. Med. 68 (1988) 691-715
61. Pinho F.M., Yu L., and Burdmann E.A. Snakebite-induced acute kidney injury in Latin America. Semin. Nephrol. 28 (2008) 354-362
62. Rehan A., Wiggins R.C., Kunkel R.G., Till G.E., and Johnson K.J. Glomerular injury and proteinuria in rats after intrarenal injection of cobra venom factor. Evidence for the role of neutrophil-derived oxygen free radicals. Am. J. Pathol. 123 (1986) 57-66
63. Rezende N.A., Amaral C.F., Bambirra E.A., Lachatt J.J., and Coimbra T.M. Functional and histopathological renal changes induced in rats by Bothrops jararaca venom. Braz. J. Med. Biol. Res. 22 (1989) 407-416
64. Ribeiro L.A., Gadia R., and Jorge M.T. Comparação entre a epidemiologia do acidente e a clínica do envenenamento por serpentes do gênero Bothrops, em adultos idosos e não idosos. Rev. Soc. Bras. Med. Trop. 41 (2008) 46-49
65. Rivière G., Choumet V., Audebert F., Sabouraud S., Debray M., Scherrmann J.M., and Bon C. Effect of antivenom on venom pharmacokinetics in experimentally envenomed rabbits: towards an optimization of antivenom therapy. J. Pharmacol. Exp. Ther. 281 (1997) 1-8
66. Rivière G., Choumet V., Saliou B., Debray M., and Bon C. Absorption and elimination of viper venom after antivenom administration. J. Pharmacol. Exp. Ther. 285 (1998) 490-495
67. 131I in mice. Toxicon 52 (2008) 526-529
68. Selvanayagam Z.E., and Gopalakrishnakone P. Tests for detection of snake venoms, toxins and venom antibodies: review on recent trends (1987-1997). Toxicon 37 (1999) 565-586
69. Sugai K., Imamura Y., Mihashi S., Ohba M., Kunikane K., Mori N., and Baba S. Plasma levels and urinary excretion of batroxobin and its defibrinogenating effects in various animal species. J. Toxicol. Sci. 11 (1986) 135-143
70. 125I-labeled batroxobin in rats and dogs. J. Toxicol. Sci. 11 (1986) 155-167
71. Sutherland S.K., and Coulter A.R. Three instructive cases of tiger snake (Notechis scutatus) envenomation and how a radioimmunoassay proved the diagnosis. Med. J. Aust. 2 (1977) 177-180
72. Tanigawa M., Maruyama M., Sugiki M., Shimaya K., Anai K., and Mihara H. Clearance and distribution of a haemorrhagic factor purified from Bothrops jararaca venom in mice. Toxicon 32 (1994) 583-593
73. Tin-Nu-Swe, Tin-Tun, Myint-Lwin, Thein-Than, Tun-Pe, Robertson J.I., Leckie B.J., Phillips W.E., and Warrell D.A. Renal ischaemia, transient glomerular leak and acute renal tubular damage in patients envenomed by Russell's vipers (Daboia russelii siamensis) in Myanmar. Trans. R. Soc. Trop. Med. Hyg. 87 (1993) 678-681
74. 131I-labeled Bothrops erythromelas venom in mice. Braz. J. Med. Biol. Res. 31 (1998) 439-443
75. Warrell D.A. Snakebites in Central and South America: epidemiology, clinical features and clinical management. In: Campbell J.A., and Lamar W.W. (Eds). Venomous Reptiles of the Western Hemisphere vol. 2 (2004), Comstock Publishing Associates/Cornell University Press, Ithaca 709-761
76. Zhao H., Zheng J., and Jiang Z. Pharmacokinetics of thrombin-like enzyme from venom of Agkistrodon halys ussuriensis Emelianov determined by ELISA in the rat. Toxicon 39 (2001) 1821-1826