Impairment of the cell-to-matrix adhesion and cytotoxicity induced by Bothrops moojeni snake venom in cultured renal tubular epithelia

Toxicology and Applied Pharmacology

Volumn 181, Issue 2, 2002, Pages 124-132

  Collares Buzato, Carla B ^a   De Paula Le Sueur, Luciana ^a   Da Cruz Höfling, Maria Alice ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Bothrops moojeni; Cell matrix interaction; Cytotoxicity; Epithelial barrier; MDCK cells; Snake venom

Indexed keywords

LACTATE DEHYDROGENASE; NEUTRAL RED; OCCLUDIN; PROTEIN ZO1; SNAKE VENOM; UVOMORULIN;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL CULTURE; CELL INTERACTION; CELL LINE; CONTROLLED STUDY; CYTOTOXICITY; EXTRACELLULAR MATRIX; GLOMERULUS; HEMODYNAMICS; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; KIDNEY TUBULE EPITHELIUM; NONHUMAN; TRANSMISSION ELECTRON MICROSCOPY;

BOTHROPS; BOTHROPS MOOJENI; SERPENTES;

EID: 0036607115     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.2002.9404     Document Type: Article

References (38)

1. Renal cortical necrosis following Bothrops jararacussu snake bite
2. Isolation of the major proteolytic enzyme from the venom of the snake Bothrops moojeni (caissaca)
3. Degradation of extracellular matrix proteins by hemorrhagic metalloproteinases
4. Identification of two strains of cultured canine renal epithelial cells (MDCK cells) which display entirely different physiological properties
5. Acidentes pot serpentes do gênero Bothrops
6. Histologic and functional renal alterations caused by Bothrops moojeni snake venom in rats
7. Echistatin, a disintegrin, inhibits sperm-oolemmal adhesion but not oocyte penetration
8. Specific in vitro biological activity of snake venom myotoxins
9. Snakebite-induced acute renal failure: An experimental model
10. Alpha v integrin antagonists induce the disassembly of focal contacts in melanoma cells
11. Resistance to acid of canine kidney (MDCK) and human colonic (T84) and ileo-caecal (HCT-8) adenocarcinoma epithelial cell monolayers in vitro
12. Histopathological and biochemical alterations induced by intramuscular injection of Bothrops asper (terciopelo) venom in mouse
13. Effects of jarastatin, a novel snake venom disintegrin, on neutrophil migration and actin cytoskeleton dynamics
14. 2+ in cultured epithelia
15. Increased tyrosine phosphorylation causes redistribution of adherens junction and tight junction proteins and perturbs paracellular barrier function in MDCK epithelia
16. Co-culture of two MDCK strains with distinct junctional protein expression: A model for intercellular junction rearrangement and cell sorting
17. 2-containing fraction
18. Dual role for nitric oxide in the regulation of plasma volume and albumin escape during endotoxin shock in conscious rats
19. Disintegrins: A family of integrin inhibitory proteins from viper venoms
20. 2 myotoxins from Bothrops snake venoms
21. Snake venom metalloproteinases and disintegrins: Interactions with cells
22. Trigramin, an RGD-containing peptide from snake venom, inhibits cell-substratum adhesion of human melanoma cells
23. Increased vesicular transfer of lanthanum nitrate across cerebral vessels evoked by Phoneutria nigriventer spider venom
24. Cell-substrate contact: Another factor may influence transepithelial electrical ressitance of cell layers cultured on permeable filters
25. Effect of 5-α-pregnan-3α-ol-20-one on nitric oxide biosynthesis and plasma volume in rats
26. Action of snake venom hemorrhagic principles on isolated glomerular basement membrane
27. Edem̀a induction by the disintegrin-like/cysteine-rich domains from a Bothrops atrox hemorrhagin
28. Renal tubular sodium handling determined by lithium clearance in partially hepatectomized rats
29. Alteration in tubular epithelial cell adhesion and mechanisms of acute renal failure
30. Direct nephrotoxicity of Russell's viper venom demonstrated in the isolated perfused rat kidney
31. Functional and histopathological renal changes induced in rats by Bothrops jararaca venom
32. FAK phosphorylation, disassembly of actin cytoskeleton and focal adhesions, and detachment of fibronectin-adherent melanoma cells
33. Contribution of focal haemorrhage and microvascular fibrin deposition to fatal envenoming by Russell's viper (Vipera russelli siamensis) in Burma
34. 1 integrin-mediated human metastatic melanoma cell adhesion and blocks experimental metastasis
35. A 28-kDa-protein with disintegrin-like structure (jararhagin-C) purified from Bothrops jararaca venom inhibits collagen- and ADP-induced platelet aggregation
36. Morphological similarities between the dog kidney cell line MDCK and the mammalian cortical collecting tubule
37. In vitro nephrotoxicity of Russell's viper venom