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Volumn 20, Issue 24, 2012, Pages 7083-7094

Synthesis and biological evaluation of 2-substituted-4-(3′,4′, 5′-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents

(12) Romagnoli, Romeo a Baraldi, Pier Giovanni a Salvador, Maria Kimatrai a Camacho, M Encarnacion a Preti, Delia a Tabrizi, Mojgan Aghazadeh a Bassetto, Marcella b Brancale, Andrea b Hamel, Ernest c Bortolozzi, Roberta d Basso, Giuseppe d Viola, Giampietro d

a UNIVERSITY OF FERRARA (Italy)

b CARDIFF UNIVERSITY (United Kingdom)

c NATIONAL CANCER INSTITUTE (United States)

d UNIVERSITY OF PADOVA (Italy)

Author keywords

Apoptosis; Colchicine site; Combretastatin A4; Thiazole; Tubulin

Indexed keywords

4 (3,4,5 TRIMETHOXYPHENYL) 2 METHYL 5 (NAPHTHALEN 2 YL)THIAZOLE; 4 (3,4,5 TRIMETHOXYPHENYL) 2 METHYL 5 PARA TOLYLTHIAZOLE; 4 (3,4,5 TRIMETHOXYPHENYL) 5 (4 METHOXYPHENYL) 2 METHYLTHIAZOLE; 4 (3,4,5 TRIMETHOXYPHENYL) 5 (4 METHOXYPHENYL) N METHYLTHIAZOL 2 AMINE; 4 (3,4,5 TRIMETHOXYPHENYL) 5 (4 METHOXYPHENYL) N,N DIMETHYLTHIAZOL 2 AMINE; 4 (3,4,5 TRIMETHOXYPHENYL) N METHYL 5 (NAPHTHALEN 2 YL)THIAZOL 2 AMINE; 4 (3,4,5 TRIMETHOXYPHENYL) N METHYL 5 PARA TOLYLTHIAZOL 2 AMINE; 4 (3,4,5 TRIMETHOXYPHENYL) N,N DIMETHYL 5 (NAPHTHALEN 3 YL)THIAZOL 2 AMINE; 4 (3,4,5 TRIMETHOXYPHENYL) N,N DIMETHYL 5 PARA TOLYLTHIAZOL 2 AMINE; 5 (4 ETHOXYPHENYL) 4 (3,4,5 TRIMETHOXYPHENYL) 2 METHYLTHIAZOLE; 5 (4 ETHOXYPHENYL) 4 (3,4,5 TRIMETHOXYPHENYL) N METHYLTHIAZOL 2 AMINE; 5 (4 ETHOXYPHENYL) 4 (3,4,5 TRIMETHOXYPHENYL) N,N DIMETHYLTHIAZOL 2 AMINE; 5 [4 (TRIFLUOROMETHYL)PHENYL] 4 (3,4,5 TRIMETHOXYPHENYL) 2 METHYLTHIAZOLE; 5 [4 (TRIFLUOROMETHYL)PHENYL] 4 (3,4,5 TRIMETHOXYPHENYL) N METHYLTHIAZOL 2 AMINE; 5 [4 (TRIFLUOROMETHYL)PHENYL] 4 (3,4,5 TRIMETHOXYPHENYL) N,N DIMETHYLTHIAZOL 2 AMINE; ANTINEOPLASTIC AGENT; COMBRETASTATIN A4; DOXORUBICIN; PACLITAXEL; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; VINBLASTINE;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; COLCHICINE; HELA CELLS; HUMANS; MICROTUBULES; MODELS, MOLECULAR; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; TUBULIN;

EID: 84870055906 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2012.10.001 Document Type: Article

Times cited : (65)

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