-
1
-
-
0035205221
-
Pivotal role of ABCA1 in reverse cholesterol transport infuencing HDL levels and susceptibility to atherosclerosis
-
Attie AD, Kastelein JP, Hayden MR. Pivotal role of ABCA1 in reverse cholesterol transport infuencing HDL levels and susceptibility to atherosclerosis. J Lipid Res. 2001;42:1717-1726.
-
(2001)
J Lipid Res.
, vol.42
, pp. 1717-1726
-
-
Attie, A.D.1
Kastelein, J.P.2
Hayden, M.R.3
-
2
-
-
0034879774
-
ABCA1. The gatekeeper for eliminating excess tissue cholesterol
-
Oram JF, Lawn RM. ABCA1. The gatekeeper for eliminating excess tissue cholesterol. J Lipid Res. 2001;42:1173-1179.
-
(2001)
J Lipid Res.
, vol.42
, pp. 1173-1179
-
-
Oram, J.F.1
Lawn, R.M.2
-
3
-
-
0032813809
-
The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease
-
Bodzioch M, Orsó E, Klucken J, Langmann T, et al. The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease. Nat Genet. 1999;22:347-351.
-
(1999)
Nat Genet.
, vol.22
, pp. 347-351
-
-
Bodzioch, M.1
Orsó, E.2
Klucken, J.3
Langmann, T.4
-
4
-
-
0032813808
-
Mutations in ABC1 in Tangier disease and familial high-density lipoprotein defciency
-
Brooks-Wilson A, Marcil M, Clee SM, et al. Mutations in ABC1 in Tangier disease and familial high-density lipoprotein defciency. Nat Genet. 1999;22:336-345.
-
(1999)
Nat Genet.
, vol.22
, pp. 336-345
-
-
Brooks-Wilson, A.1
Marcil, M.2
Clee, S.M.3
-
5
-
-
0032813660
-
Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1
-
Rust S, Rosier M, Funke H, Real J, Amoura Z, Piette JC, Deleuze JF, Brewer HB, Duverger N, Denèfe P, Assmann G. Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1. Nat Genet. 1999;22:352-355.
-
(1999)
Nat Genet.
, vol.22
, pp. 352-355
-
-
Rust, S.1
Rosier, M.2
Funke, H.3
Real, J.4
Amoura, Z.5
Piette, J.C.6
Deleuze, J.F.7
Brewer, H.B.8
Duverger, N.9
Denèfe, P.10
Assmann, G.11
-
6
-
-
25444463073
-
ATP-binding cassette transporter A1: A cell cholesterol exporter that protects against cardiovascular disease
-
Oram JF, Heinecke JW. ATP-binding cassette transporter A1: a cell cholesterol exporter that protects against cardiovascular disease. Physiol Rev. 2005;85:1343-1372.
-
(2005)
Physiol Rev.
, vol.85
, pp. 1343-1372
-
-
Oram, J.F.1
Heinecke, J.W.2
-
7
-
-
0037253264
-
A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I
-
Wang N, Chen W, Linsel-Nitschke P, Martinez LO, Agerholm-Larsen B, Silver DL, Tall AR. A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I. J Clin Invest. 2003;111:99-107.
-
(2003)
J Clin Invest.
, vol.111
, pp. 99-107
-
-
Wang, N.1
Chen, W.2
Linsel-Nitschke, P.3
Martinez, L.O.4
Agerholm-Larsen, B.5
Silver, D.L.6
Tall, A.R.7
-
8
-
-
33645502340
-
Intestinal ABCA1 directly contributes to HDL biogenesis in vivo
-
Brunham LR, Kruit JK, Iqbal J, Fievet C, Timmins JM, Pape TD, Coburn BA, Bissada N, Staels B, Groen AK, Hussain MM, Parks JS, Kuipers F, Hayden MR. Intestinal ABCA1 directly contributes to HDL biogenesis in vivo. J Clin Invest. 2006;116:1052-1062.
-
(2006)
J Clin Invest.
, vol.116
, pp. 1052-1062
-
-
Brunham, L.R.1
Kruit, J.K.2
Iqbal, J.3
Fievet, C.4
Timmins, J.M.5
Pape, T.D.6
Coburn, B.A.7
Bissada, N.8
Staels, B.9
Groen, A.K.10
Hussain, M.M.11
Parks, J.S.12
Kuipers, F.13
Hayden, M.R.14
-
9
-
-
20944435724
-
Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I
-
Timmins JM, Lee JY, Boudyguina E, Kluckman KD, Brunham LR, Mulya A, Gebre AK, Coutinho JM, Colvin PL, Smith TL, Hayden MR, Maeda N, Parks JS. Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I. J Clin Invest. 2005;115:1333-1342.
-
(2005)
J Clin Invest.
, vol.115
, pp. 1333-1342
-
-
Timmins, J.M.1
Lee, J.Y.2
Boudyguina, E.3
Kluckman, K.D.4
Brunham, L.R.5
Mulya, A.6
Gebre, A.K.7
Coutinho, J.M.8
Colvin, P.L.9
Smith, T.L.10
Hayden, M.R.11
Maeda, N.12
Parks, J.S.13
-
10
-
-
33847722655
-
Beta-cell ABCA1 infuences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment
-
Brunham LR, Kruit JK, Pape TD, Timmins JM, Reuwer AQ, Vasanji Z, Marsh BJ, Rodrigues B, Johnson JD, Parks JS, Verchere CB, Hayden MR. Beta-cell ABCA1 infuences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment. Nat Med. 2007;13:340-347.
-
(2007)
Nat Med.
, vol.13
, pp. 340-347
-
-
Brunham, L.R.1
Kruit, J.K.2
Pape, T.D.3
Timmins, J.M.4
Reuwer, A.Q.5
Vasanji, Z.6
Marsh, B.J.7
Rodrigues, B.8
Johnson, J.D.9
Parks, J.S.10
Verchere, C.B.11
Hayden, M.R.12
-
11
-
-
63849221643
-
Specifc loss of brain ABCA1 increases brain cholesterol uptake and infuences neuronal structure and function
-
Karasinska JM, Rinninger F, Lütjohann D, Ruddle P, Franciosi S, Kruit JK, Singaraja RR, Hirsch-Reinshagen V, Fan J, Brunham LR, Bissada N, Ramakrishnan R, Wellington CL, Parks JS, Hayden MR. Specifc loss of brain ABCA1 increases brain cholesterol uptake and infuences neuronal structure and function. J Neurosci. 2009;29:3579-3589.
-
(2009)
J Neurosci.
, vol.29
, pp. 3579-3589
-
-
Karasinska, J.M.1
Rinninger, F.2
Lütjohann, D.3
Ruddle, P.4
Franciosi, S.5
Kruit, J.K.6
Singaraja, R.R.7
Hirsch-Reinshagen, V.8
Fan, J.9
Brunham, L.R.10
Bissada, N.11
Ramakrishnan, R.12
Wellington, C.L.13
Parks, J.S.14
Hayden, M.R.15
-
12
-
-
53149102864
-
Increased cellular free cholesterol in macrophage-specifc Abca1 knock-out mice enhances pro-infammatory response of macrophages
-
Zhu X, Lee J Y, Timmins JM, Brown JM, Boudyguina E, Mulya A, Gebre AK, Willingham MC, Hiltbold EM, Mishra N, Maeda N, Parks JS. Increased cellular free cholesterol in macrophage-specifc Abca1 knock-out mice enhances pro-infammatory response of macrophages. J Biol Chem. 2008;283:22930-22941.
-
(2008)
J Biol Chem.
, vol.283
, pp. 22930-22941
-
-
Zhu, X.1
Lee, J.Y.2
Timmins, J.M.3
Brown, J.M.4
Boudyguina, E.5
Mulya, A.6
Gebre, A.K.7
Willingham, M.C.8
Hiltbold, E.M.9
Mishra, N.10
Maeda, N.11
Parks, J.S.12
-
13
-
-
56549109283
-
Increased infamma-tory gene expression in ABC transporter-defcient macrophages: Free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infltration of atherosclerotic lesions
-
Yvan-Charvet L, Welch C, Pagler TA, Ranalletta M, Lamkanf M, Han S, Ishibashi M, Li R, Wang N, Tall AR. Increased infamma-tory gene expression in ABC transporter-defcient macrophages: free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infltration of atherosclerotic lesions. Circulation. 2008;118:1837-1847.
-
(2008)
Circulation.
, vol.118
, pp. 1837-1847
-
-
Yvan-Charvet, L.1
Welch, C.2
Pagler, T.A.3
Ranalletta, M.4
Lamkanf, M.5
Han, S.6
Ishibashi, M.7
Li, R.8
Wang, N.9
Tall, A.R.10
-
14
-
-
78149355932
-
Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor traffcking to lipid rafts by reduction of lipid raft cholesterol
-
Zhu X, Owen JS, Wilson MD, Li H, Griffths GL, Thomas MJ, Hiltbold EM, Fessler MB, Parks JS. Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor traffcking to lipid rafts by reduction of lipid raft cholesterol. J Lipid Res. 2010;51:3196-3206.
-
(2010)
J Lipid Res.
, vol.51
, pp. 3196-3206
-
-
Zhu, X.1
Owen, J.S.2
Wilson, M.D.3
Li, H.4
Griffths, G.L.5
Thomas, M.J.6
Hiltbold, E.M.7
Fessler, M.B.8
Parks, J.S.9
-
15
-
-
53449094756
-
Listeria monocytogenes, a unique model in infection biology: An overview
-
Cossart P, Toledo-Arana A. Listeria monocytogenes, a unique model in infection biology: an overview. Microbes Infect. 2008;10:1041-1050.
-
(2008)
Microbes Infect.
, vol.10
, pp. 1041-1050
-
-
Cossart, P.1
Toledo-Arana, A.2
-
16
-
-
20144371061
-
Increased cholesterol deposition, expression of scavenger receptors, and response to chemotactic factors in Abca1-defcient macrophages
-
Francone OL, Royer L, Boucher G, Haghpassand M, Freeman A, Brees D, Aiello RJ. Increased cholesterol deposition, expression of scavenger receptors, and response to chemotactic factors in Abca1-defcient macrophages. Arterioscler Thromb Vasc Biol. 2005;25:1198-1205.
-
(2005)
Arterioscler Thromb Vasc Biol.
, vol.25
, pp. 1198-1205
-
-
Francone, O.L.1
Royer, L.2
Boucher, G.3
Haghpassand, M.4
Freeman, A.5
Brees, D.6
Aiello, R.J.7
-
17
-
-
27644454355
-
A specifc role of inte-grin Mac-1 in accelerated macrophage effux to the lymphatics
-
Cao C, Lawrence DA, Strickland DK, Zhang L. A specifc role of inte-grin Mac-1 in accelerated macrophage effux to the lymphatics. Blood. 2005;106:3234-3241.
-
(2005)
Blood.
, vol.106
, pp. 3234-3241
-
-
Cao, C.1
Lawrence, D.A.2
Strickland, D.K.3
Zhang, L.4
-
18
-
-
84855928422
-
The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques
-
van Gils JM, Derby MC, Fernandes LR, et al. The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques. Nat Immunol. 2012;13:136-143.
-
(2012)
Nat Immunol.
, vol.13
, pp. 136-143
-
-
Van Gils, J.M.1
Derby, M.C.2
Fernandes, L.R.3
-
19
-
-
0035976638
-
Nuclear receptors and lipid physiology: Opening the X-files
-
Chawla A, Repa JJ, Evans RM, Mangelsdorf DJ. Nuclear receptors and lipid physiology: opening the X-files. Science. 2001;294:1866-1870.
-
(2001)
Science.
, vol.294
, pp. 1866-1870
-
-
Chawla, A.1
Repa, J.J.2
Evans, R.M.3
Mangelsdorf, D.J.4
-
20
-
-
5444235922
-
LXR-dependent gene expression is important for macrophage survival and the innate immune response
-
Joseph SB, Bradley MN, Castrillo A, Bruhn KW, Mak PA, Pei L, Hogenesch J, O'connell RM, Cheng G, Saez E, Miller JF, Tontonoz P. LXR-dependent gene expression is important for macrophage survival and the innate immune response. Cell. 2004;119:299-309.
-
(2004)
Cell.
, vol.119
, pp. 299-309
-
-
Joseph, S.B.1
Bradley, M.N.2
Castrillo, A.3
Bruhn, K.W.4
Mak, P.A.5
Pei, L.6
Hogenesch, J.7
O'Connell, R.M.8
Cheng, G.9
Saez, E.10
Miller, J.F.11
Tontonoz, P.12
-
21
-
-
11144221176
-
Activation of liver X receptors and retinoid X receptors prevents bacterial-induced macrophage apoptosis
-
Valledor AF, Hsu LC, Ogawa S, Sawka-Verhelle D, Karin M, Glass CK. Activation of liver X receptors and retinoid X receptors prevents bacterial-induced macrophage apoptosis. Proc Natl Acad Sci USA. 2004;101:17813-17818.
-
(2004)
Proc Natl Acad Sci USA.
, vol.101
, pp. 17813-17818
-
-
Valledor, A.F.1
Hsu, L.C.2
Ogawa, S.3
Sawka-Verhelle, D.4
Karin, M.5
Glass, C.K.6
-
22
-
-
33645902493
-
Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2
-
Serbina NV, Pamer EG. Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nat Immunol. 2006;7:311-317.
-
(2006)
Nat Immunol.
, vol.7
, pp. 311-317
-
-
Serbina, N.V.1
Pamer, E.G.2
-
23
-
-
0023841073
-
Macrophages secrete a novel heparin-binding protein with infammatory and neutrophil chemo-kinetic properties
-
Wolpe SD, Davatelis G, Sherry B, Beutler B, Hesse DG, Nguyen HT, Moldawer LL, Nathan CF, Lowry SF, Cerami A. Macrophages secrete a novel heparin-binding protein with infammatory and neutrophil chemo-kinetic properties. J Exp Med. 1988;167:570-581.
-
(1988)
J Exp Med.
, vol.167
, pp. 570-581
-
-
Wolpe, S.D.1
Davatelis, G.2
Sherry, B.3
Beutler, B.4
Hesse, D.G.5
Nguyen, H.T.6
Moldawer, L.L.7
Nathan, C.F.8
Lowry, S.F.9
Cerami, A.10
-
24
-
-
79251631663
-
Deletion of ABCA1 and ABCG1 impairs macrophage migration because of increased Rac1 signaling
-
Pagler TA, Wang M, Mondal M, Murphy AJ, Westerterp M, Moore KJ, Maxfeld FR, Tall AR. Deletion of ABCA1 and ABCG1 impairs macrophage migration because of increased Rac1 signaling. Circ Res. 2011;108:194-200.
-
(2011)
Circ Res.
, vol.108
, pp. 194-200
-
-
Pagler, T.A.1
Wang, M.2
Mondal, M.3
Murphy, A.J.4
Westerterp, M.5
Moore, K.J.6
Maxfeld, F.R.7
Tall, A.R.8
-
25
-
-
0242361567
-
Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism
-
Castrillo A, Joseph SB, Vaidya SA, Haberland M, Fogelman AM, Cheng G, Tontonoz P. Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism. Mol Cell. 2003;12:805-816.
-
(2003)
Mol Cell.
, vol.12
, pp. 805-816
-
-
Castrillo, A.1
Joseph, S.B.2
Vaidya, S.A.3
Haberland, M.4
Fogelman, A.M.5
Cheng, G.6
Tontonoz, P.7
-
26
-
-
0027530129
-
Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodefciency mice with listeriosis, and interleukin 10 is a physiologic antagonist
-
Tripp CS, Wolf SF, Unanue ER. Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodefciency mice with listeriosis, and interleukin 10 is a physiologic antagonist. Proc Natl Acad Sci USA. 1993;90:3725-3729.
-
(1993)
Proc Natl Acad Sci USA.
, vol.90
, pp. 3725-3729
-
-
Tripp, C.S.1
Wolf, S.F.2
Unanue, E.R.3
-
27
-
-
0036785630
-
Critical roles of myeloid differentiation factor 88-dependent proinfam-matory cytokine release in early phase clearance of Listeria monocyto-genes in mice
-
Seki E, Tsutsui H, Tsuji NM, Hayashi N, Adachi K, Nakano H, Futatsugi-Yumikura S, Takeuchi O, Hoshino K, Akira S, Fujimoto J, Nakanishi K. Critical roles of myeloid differentiation factor 88-dependent proinfam-matory cytokine release in early phase clearance of Listeria monocyto-genes in mice. J Immunol. 2002;169:3863-3868.
-
(2002)
J Immunol.
, vol.169
, pp. 3863-3868
-
-
Seki, E.1
Tsutsui, H.2
Tsuji, N.M.3
Hayashi, N.4
Adachi, K.5
Nakano, H.6
Futatsugi-Yumikura, S.7
Takeuchi, O.8
Hoshino, K.9
Akira, S.10
Fujimoto, J.11
Nakanishi, K.12
-
28
-
-
0036785557
-
MyD88-dependent but Toll-like receptor 2-independent innate immunity to Listeria: No role for either in macrophage listericidal activity
-
Edelson BT, Unanue ER. MyD88-dependent but Toll-like receptor 2-independent innate immunity to Listeria: no role for either in macrophage listericidal activity. J Immunol. 2002;169:3869-3875.
-
(2002)
J Immunol.
, vol.169
, pp. 3869-3875
-
-
Edelson, B.T.1
Unanue, E.R.2
-
29
-
-
3042606551
-
Effects of infection and infammation on lipid and lipoprotein metabolism: Mechanisms and consequences to the host
-
Khovidhunkit W, Kim MS, Memon RA, Shigenaga JK, Moser AH, Feingold KR, Grunfeld C. Effects of infection and infammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host. J Lipid Res. 2004;45:1169-1196.
-
(2004)
J Lipid Res.
, vol.45
, pp. 1169-1196
-
-
Khovidhunkit, W.1
Kim, M.S.2
Memon, R.A.3
Shigenaga, J.K.4
Moser, A.H.5
Feingold, K.R.6
Grunfeld, C.7
-
30
-
-
45549091996
-
Additive roles for MCP-1 and MCP-3 in CCR2-mediated recruitment of infammatory monocytes during Listeria monocytogenes infection
-
Jia T, Serbina NV, Brandl K, Zhong MX, Leiner IM, Charo IF, Pamer EG. Additive roles for MCP-1 and MCP-3 in CCR2-mediated recruitment of infammatory monocytes during Listeria monocytogenes infection. J Immunol. 2008;180:6846-6853.
-
(2008)
J Immunol.
, vol.180
, pp. 6846-6853
-
-
Jia, T.1
Serbina, N.V.2
Brandl, K.3
Zhong, M.X.4
Leiner, I.M.5
Charo, I.F.6
Pamer, E.G.7
-
31
-
-
0030699387
-
Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor
-
Kurihara T, Warr G, Loy J, Bravo R. Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor. J Exp Med. 1997;186:1757-1762.
-
(1997)
J Exp Med.
, vol.186
, pp. 1757-1762
-
-
Kurihara, T.1
Warr, G.2
Loy, J.3
Bravo, R.4
-
32
-
-
0346849667
-
Sequential MyD88-independent and-dependent activation of innate immune responses to intracellular bacterial infection
-
Serbina N V, Kuziel W, Flavell R, Akira S, Rollins B, Pamer EG. Sequential MyD88-independent and-dependent activation of innate immune responses to intracellular bacterial infection. Immunity. 2003;19:891-901.
-
(2003)
Immunity.
, vol.19
, pp. 891-901
-
-
Serbina, N.V.1
Kuziel, W.2
Flavell, R.3
Akira, S.4
Rollins, B.5
Pamer, E.G.6
|