Purging of memories from conscious awareness tracked in the human brain

Journal of Neuroscience

Volumn 32, Issue 47, 2012, Pages 16785-16794

  Levy, Benjamin J ^a   Anderson, Michael C ^b  

^a UNIVERSITY OF SAN FRANCISCO   (United States)

^b MRC COGNITION AND BRAIN SCIENCES UNIT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; ASSOCIATION; AWARENESS; BEHAVIOR; CONSCIOUSNESS; CONTROLLED STUDY; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HIPPOCAMPUS; HUMAN; HUMAN EXPERIMENT; MALE; MEMORY; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RECALL; STIMULATION; TASK PERFORMANCE;

ADOLESCENT; ADULT; AWARENESS; BRAIN; CONSCIOUSNESS; CUES; FEMALE; HIPPOCAMPUS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MEMORY; MENTAL RECALL; PHOTIC STIMULATION; PSYCHOMOTOR PERFORMANCE; READING; THINKING; YOUNG ADULT;

EID: 84870040470     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2640-12.2012     Document Type: Article

References (39)

1. Anderson MC (2003) Rethinking interference theory: executive control and the mechanisms of forgetting. J Mem Lang 49:415-445. CrossRef
2. Anderson MC, Green C (2001) Suppressing unwanted memories by executive control. Nature 410:366-369. CrossRef Medline
3. Anderson MC, Huddleston E (2012) Towards a cognitive and neurobiological model of motivated forgetting. In: True and false recovered memories: toward a reconciliation of the debate, Vol. 58: Nebraska Symposium on Motivation (Belli RF, ed), pp 53-120. New York: Springer.
4. Anderson MC, Spellman BA (1995) On the status of inhibitory mechanisms in cognition: memory retrieval as a model case. Psychol Rev 102:68-100. CrossRef Medline
5. Anderson MC, Ochsner KN, Kuhl B, Cooper J, Robertson E, Gabrieli SW, Glover GH, Gabrieli JD (2004) Neural systems underlying the suppression of unwanted memories. Science 303:232-235. CrossRef Medline
6. Beckmann CF, Jenkinson M, Smith SM (2003) General multi-level linear modelling for group analysis in fMRI. Neuroimage 20:1052-1063. CrossRef Medline
7. Benoit, RG, and Anderson, MC (2012) Opposing mechanisms support the voluntary forgetting of unwanted memories. Neuron 76:450-460
8. Cerf M, Thiruvengadam N, Mormann F, Kraskov A, Quiroga RQ, Koch C, Fried I (2010) On-line voluntary control of human temporal lobe neurons. Nature 467:1104-1108. CrossRef Medline
9. Chalmers D (1995) Facing up to the problem of consciousness. J Consciousness Studies 2:200-219
10. Clark RE, Squire LR (1998) Classical conditioning and brain systems: the role of awareness. Science 280:77-81. CrossRef Medline
11. Corallo G, Sackur J, Dehaene S, Sigman M (2008) Limits on introspection: distorted subjective time during the dual-task bottleneck. Psychol Sci 19:1110-1117. CrossRef Medline
12. Crick F, Koch C (1995) Are we aware of neural activity in primary visual cortex? Nature 375:121-123. CrossRef Medline
13. Dehaene S, Kerszberg M, Changeux JP (1998) A neuronal model of a global workspace in effortful cognitive tasks. Proc Natl Acad Sci U S A 95: 14529-14534. CrossRef Medline
14. Dehaene S, Artiges E, Naccache L, Martelli C, Viard A, Schurhoff F, Recasens C, Martinot ML, Leboyer M, Martinot JL (2003) Conscious and subliminal conflicts in normal subjects and patients with schizophrenia: the role of the anterior cingulate. Proc Natl Acad Sci U S A 100:13722-13727. CrossRef Medline
15. Depue BE, Curran T, Banich MT (2007) Prefrontal regions orchestrate suppression of emotional memories via a two-phase process. Science 317: 215-219. CrossRef Medline
16. Dudai Y (2004) The neurobiology of consolidations, or, how stable is the engram? Annu Rev Psychol 55:51-86 CrossRef
17. Eichenbaum H, Yonelinas AP, Ranganath C (2007) The medial temporal lobe and recognition memory. Annu Rev Neurosci 30:123-152. CrossRef Medline
18. Eldridge LL, Knowlton BJ, Furmanski CS, Bookheimer SY, Engel SA (2000) Remembering episodes: a selective role for the hippocampus during retrieval. Nat Neurosci 3:1149-1152. CrossRef Medline
19. Gazzaley A, Cooney JW, Rissman J, D'Esposito M (2005) Top-down suppression deficit underlies working memory impairment in normal aging. Nat Neurosci 8:1298-1300. CrossRef Medline
20. Gelbard-Sagiv H, Mukamel R, Harel M, Malach R, Fried I (2008) Internally generated reactivation of single neurons in human hippocampus during free recall. Science 322:96-101. CrossRef Medline
21. Insausti R, Juottonen K, Soininen H, Insausti AM, Partanen K, Vainio P, Laakso MP, Pitkänen A (1998) MR volumetric analysis of the human entorhinal, perirhinal, and temporopolar cortices. Am J Neuroradiol 19: 659-671
22. Medline Jenkinson M, Smith S (2001) A global optimisation method for robust affine registration of brain images. Med Image Anal 5:143-156 CrossRef
23. Jenkinson M, Bannister P, Brady M, Smith S (2002) Improved optimisation for the robust and accurate linear registration and motion correction of brain images. Neuroimage 17:825-841. CrossRef Medline
24. Kreiman G, Koch C, Fried I (2000) Imagery neurons in the human brain. Nature 408:357-361. CrossRef Medline
25. Kreiman G, Fried I, Koch C (2002) Single-neuron correlates of subjective vision in the human medial temporal lobe. Proc Natl Acad Sci U S A 99:8378-8383. CrossRef Medline
26. Kuhl BA, Dudukovic NM, Kahn I, Wagner AD (2007) Decreased demands on cognitive control reveal neural processing benefits of forgetting. Nat Neurosci 10:908-914. CrossRef Medline
27. Mayr U (2004) Conflict, consciousness, and control. Trends Cogn Sci 8:145-148. CrossRef Medline
28. Montaldi D, Mayes AR (2010) The role of recollection and familiarity in the functional differentiation of the medial temporal lobes. Hippocampus 20:1291-1314. CrossRef Medline
29. Nader K, Schafe GE, Le Doux JE (2000) Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval. Nature 406: 722-726. CrossRef Medline
30. Pruessner JC, Li LM, Serles W, Pruessner M, Collins DL, Kabani N, Lupien S, Evans AC (2000) Volumetry of hippocampus and amygdala with highresolution MRI and three-dimensional analysis software: minimizing the discrepancies between laboratories. Cereb Cortex 10:433-442. CrossRef Medline
31. Pruessner JC, Kohler S, Crane J, Pruessner M, Lord C, Byrne A, Kabani N, Collins DL, Evans AC (2002) Volumetry of temporopolar, perirhinal, entorhinal and parahippocampal cortex from high-resolution MR images: considering the variability of the collateral sulcus. Cereb Cortex 12:1342-1353. CrossRef Medline
32. Rees G, Kreiman G, Koch C (2002) Neural correlates of consciousness in humans. Nat Rev Neurosci 3:261-270. CrossRef Medline
33. Sergent C, Dehaene S (2004) Is consciousness a gradual phenomenon? Evidence for an all-or-none bifurcation during the attentional blink. Psychol Sci 15:720-728. CrossRef Medline
34. Sergent C, Baillet S, Dehaene S (2005) Timing of the brain events underlying access to consciousness during the attentional blink. Nat Neurosci 8:1391-1400. CrossRef Medline
35. Smith SM (2002) Fast robust automated brain extraction. HumBrain Mapp 17:143-155. CrossRef
36. Woolrich MW, Ripley BD, Brady M, Smith SM (2001) Temporal autocorrelation in univariate linear modelling of fMRI data. Neuroimage 14: 1370-1386. CrossRef Medline
37. Worsley KJ, Evans AC, Marrett S, Neelin P (1992) A three-dimensional statistical analysis for CBF activation studies in human brain. J Cereb Blood Flow Metab 12:900-918. CrossRef
38. Zeineh MM, Engel SA, Bookheimer SY (2000) Application of cortical unfolding techniques to functional MRI of the human hippocampal region. Neuroimage 11:668-683. CrossRef Medline
39. Zeineh MM, Engel SA, Thompson PM, Bookheimer SY (2003) Dynamics of the hippocampus during encoding and retrieval of face-name pairs. Science 299:577-580. CrossRef Medline