Internally generated reactivation of single neurons in human hippocampus during free recall

Science

Volumn 322, Issue 5898, 2008, Pages 96-101

  Gelbard Sagiv, Hagar ^a   Mukamel, Roy ^b   Harel, Michal ^a   Malach, Rafael ^a   Fried, Itzhak ^b,c  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; HOMINID; MEMORY;

ARTICLE; BRAIN FUNCTION; CLINICAL ARTICLE; ENTORHINAL CORTEX; HIPPOCAMPUS; HUMAN; HUMAN CELL; MEMORY; NERVE CELL; PRIORITY JOURNAL; RECALL;

ACTION POTENTIALS; BRAIN MAPPING; CUES; ELECTRODES, IMPLANTED; ENTORHINAL CORTEX; EPILEPSY; HIPPOCAMPUS; HUMANS; MENTAL RECALL; NEURONS;

PRIMATES;

EID: 52449112701     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1164685     Document Type: Article

References (37)

1. W. B. Scoville, B. Milner, J. Neurol. Neurosurg. Psychiatry 20, 11 (1957).
2. L. R. Squire, C. E. Stark, R. E. Clark, Annu. Rev. Neurosci. 27, 279 (2004).
3. H. Eichenbaum, Neuron 44, 109 (2004).
4. M. Moscovitch, L. Nadel, G. Winocur, A. Gilboa, R. S. Rosenbaum, Curr. Opin. Neurobiol. 16, 179 (2006).
5. I. Fried, K. A. MacDonald, C. L. Wilson, Neuron 18, 753 (1997).
6. G. Kreiman, C. Koch, I. Fried, Nat. Neurosci. 3, 946 (2000).
7. G. Heit, M. E. Smith, E. Halgren, Nature 333, 773 (1988).
8. R. Q. Quiroga, L. Reddy, G. Kreiman, C. Koch, I. Fried, Nature 435, 1102 (2005).
9. R. Q. Quiroga, G. Kreiman, C. Koch, I. Fried, Trends Cogn. Sci. 12, 87 (2008).
10. U. Rutishauser, A. N. Mamelak, E. M. Schuman, Neuron 49, 805 (2006).
11. I. V. Viskontas, B. J. Knowlton, P. N. Steinmetz, I. Fried, J. Cogn. Neurosci. 18, 1654 (2006).
12. N. J. Fortin, K. L. Agster, H. B. Eichenbaum, Nat. Neurosci. 5, 458 (2002).
13. J. E. Lisman, Neuron 22, 233 (1999).
14. I. Fried et al., J. Neurosurg. 91, 697 (1999).
15. Materials and methods are available as supporting material on Science Online.
16. Y. Miyashita, Science 306, 435 (2004).
17. R. N. Henson, M. D. Rugg, T. Shallice, R. J. Dolan, J. Cogn. Neurosci. 12, 913 (2000).
18. G. A. Ojemann, J. Schoenfield-McNeill, D. P. Corina, Nat. Neurosci. 5, 64 (2002).
19. S. M. Polyn, M. J. Kahana, Trends Cogn. Sci. 12, 24 (2008).
20. D. L. Schacter, Philos. Trans. R. Soc. Lond. B Biol. Sci. 352, 1689 (1997).
21. S. M. Polyn, V. S. Natu, J. D. Cohen, K. A. Norman, Science 310, 1963 (2005).
22. L. Nyberg, R. Habib, A. R. McIntosh, E. Tulving, Proc. Natl. Acad. Sci. U.S.A. 97, 11120 (2000).
23. M. E. Wheeler, S. E. Petersen, R. L. Buckner, Proc. Natl. Acad. Sci. U.S.A. 97, 11125 (2000).
24. I. Kahn, L. Davachi, A. D. Wagner, J. Neurosci. 24, 4172 (2004).
25. G. Kreiman, C. Koch, I. Fried, Nature 408, 357 (2000).
26. J. O'Keefe, J. Dostrovsky, Brain Res. 34, 171 (1971).
27. M. A. Wilson, B. L. McNaughton, Science 265, 676 (1994).
28. W. E. Skaggs, B. L. McNaughton, Science 271, 1870 (1996).
29. A. K. Lee, M. A. Wilson, Neuron 36, 1183 (2002).
30. K. Diba, G. Buzsáki, Nat. Neurosci. 10, 1241 (2007).
31. D. J. Foster, M. A. Wilson, Nature 440, 680 (2006).
32. A. Johnson, A. D. Redish, J. Neurosci. 27, 12176 (2007).
33. E. Pastalkova, V. Itskov, A. Amarasingham, G. Buzsáki, Science 321, 1322 (2008).
34. J. O'Keefe, L. Nadel, The Hippocampus as a Cognitive Map (Oxford Univ. Press, Oxford, 1978), pp. 380-410.
35. E. R. Wood, P. A. Dudchenko, H. Eichenbaum, Nature 397, 613 (1999).
36. C. M. Bird, N. Burgess, Nat. Rev. Neurosci. 9, 182 (2008).
37. We thank the patients for their cooperation and participation in this study. We also thank E. Ho, B. Scott, E. Behnke, R. Kadivar, T. Fields, A. Postolova, K. Laird, C. Wilson, R. Quian-Quiroga, A. Kraskov, F. Mormann, and M. Cerf for assistance with data acquisition; B. Salaz and I. Wainwright for administrative help; and I. Kahn, Y. Nir, G. Buzsáki, E. Pastalkova, and S. Gilaie-Dotan for discussions and comments on this manuscript. This work was supported by NINDS (to I. Fried), Israel Science Foundation (to R. Malach), Binational United States-Israel grant (to I. Fried and R. Malach), and Human Frontier Science Program Organization (HFSPO) fellowship (to R. Mukamel).