Active site plasticity within the glycoside hydrolase NagZ underlies a dynamic mechanism of substrate distortion

Chemistry and Biology

Volumn 19, Issue 11, 2012, Pages 1471-1482

  Bacik, John Paul ^a   Whitworth, Garrett E ^b   Stubbs, Keith A ^b,c   Vocadlo, David J ^b   Mark, Brian L ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b SIMON FRASER UNIVERSITY   (Canada)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; GLYCOSIDASE; HISTIDINE; NAGZ PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS SUBTILIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME KINETICS; NONHUMAN; PLASTICITY; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM;

ACETYLGLUCOSAMINE; BACILLUS SUBTILIS; BACTERIAL PROTEINS; CATALYTIC DOMAIN; DISACCHARIDES; GLYCOSIDE HYDROLASES; MODELS, MOLECULAR; PROTEIN CONFORMATION; SALMONELLA TYPHIMURIUM;

BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); NEGIBACTERIA; SALMONELLA TYPHIMURIUM;

EID: 84870006158     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2012.09.016     Document Type: Article

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