How bacteria consume their own exoskeletons (turnover and recycling of cell wall peptidoglycan)

Microbiology and Molecular Biology Reviews

Volumn 72, Issue 2, 2008, Pages 211-227

  Park, James T ^a   Uehara, Tsuyoshi ^a,b  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLGLUCOSAMINIDASE; ACYLTRANSFERASE; AMIDASE; AMINO ACID; AMPG PERMEASE; ANHYDRO N ACETYLMURAMIC ACID KINASE; BACTERIAL ENZYME; BETA LACTAMASE; CARBOXYPEPTIDASE; EPIMERASE; GAMMA DEXTRO GLUTAMYL MESO DIAMINOPIMELATE AMIDASE; LIGASE; MURCIN; N ACETYL BETA GLUCOSAMINIDASE; N ACETYLGLUCOSAMINE 6 PARA DEACETYLASE; N ACETYLGLUCOSAMINE KINASE; PEPTIDOGLYCAN; PERMEASE; PHOSPHOTRANSFERASE; TRIPEPTIDE;

BACTERIAL CELL WALL; BACTERIUM; CELL ELONGATION; CELL SEPARATION; CELL SEPTATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ESCHERICHIA COLI; EXOSKELETON; GENE CONTROL; NONHUMAN; PROTEIN ANALYSIS; PROTEIN METABOLISM; PROTEIN STRUCTURE; PROTEIN TRANSPORT; REVIEW; SKELETON;

BACTERIAL PROTEINS; BETA-LACTAMASES; CARBOHYDRATE SEQUENCE; CELL WALL; ESCHERICHIA COLI; MEMBRANE TRANSPORT PROTEINS; MOLECULAR SEQUENCE DATA; PEPTIDOGLYCAN;

ESCHERICHIA COLI; NEGIBACTERIA;

EID: 44949258242     PISSN: 10922172     EISSN: None     Source Type: Journal    
DOI: 10.1128/MMBR.00027-07     Document Type: Review

References (135)

1. Adam, A., and E. Lederer. 1984. Muramyl peptides: immunomodulators, sleep factors, and vitamins. Med. Res. Rev. 4:111-152.
2. Arminjon, F., M. Guinand, M. J. Vacheron, and G. Michel. 1977. Specificity profiles of the membrane-bound γ-D-glutamyl-(L)meso- diaminopimelateendopeptidase and LD-carboxypeptidase from Bacillus sphaericus 9602. Eur. J. Biochem. 73:557-565.
3. Asensio, C., and M. Ruiz-Amil. 1966. N-Acetyl-D-glucosamine kinase. II. Escherichia coli. Methods Enzymol. 9:421-425.
4. Bagge, N., M. Schuster, M. Hentzer, O. Ciofu, M. Givskov, E. P. Greenberg, and N. Høiby. 2004. Pseudomonas aeruginosa biofilms exposed to imipenem exhibit changes in global gene expression and β-lactamase and alginate production. Antimicrob. Agents Chemother. 48:1175-1187.
5. Baum, E. Z., S. M. Crespo-Carbone, D. Abbanat, B. Foleno, A. Maden, R. Goldschmidt, and K. Bush. 2006. Utility of muropeptide ligase for identification of inhibitors of the cell wall biosynthesis enzyme MurF. Antimicrob. Agents Chemother. 50:230-236.
6. Baum, E. Z., S. M. Crespo-Carbone, B. Foleno, S. Peng, J. J. Hilliard, D. Abbanat, R. Goldschmidt, and K. Bush. 2005. Identification of a dithiazoline inhibitor of Escherichia coli L,D-carboxypeptidase A. Antimicrob. Agents Chemother. 49:4500-4507.
7. Berger, E. A., and L. A. Heppel. 1972. A binding protein involved in the transport of cystine and diaminopimelic acid in Escherichia coli. J. Biol. Chem. 247:7684-7694.
8. Bertsche, U., E. Breukink, T. Kast, and W. Vollmer. 2005. In vitro murein peptidoglycan synthesis by dimers of the bifunctional transglycosylase-transpeptidase PBP1B from Escherichia coli. J. Biol. Chem. 280:38096-38101.
9. Bi, E., and J. Lutkenhaus. 1993. Cell division inhibitors SulA and MinCD prevent formation of the FtsZ ring. J. Bacteriol. 175:1118-1125.
10. Bina, X., V. Perreten, and S. B. Levy. 2003. The periplasmic protein MppA requires an additional mutated locus to repress marA expression in Escherichia coli. J. Bacteriol. 185:1465-1469.
11. Boneca, I. G. 2005. The role of peptidoglycan in pathogenesis Curr. Opin. Microbiol. 8:46-53.
12. Boothby, D., L. Daneo-Moore, M. L. Higgins, J. Coyette, and G. D. Shockman. 1973. Turnover of bacterial cell wall peptidoglycans. J. Biol. Chem. 248:2161-2169.
13. Broome-Smith, J. K., M. Tadayyon, and Y. Zhang. 1990. β-Lactamase as a probe of membrane protein assembly and protein export. Mol. Microbiol. 4:1637-1644.
14. Burdett, I. D., and R. G. Murray. 1974. Electron microscope study of septum formation in Escherichia coli strains B and B-r during synchronous growth. J. Bacteriol. 119:1039-1056.
15. Burland, V., G. Plunkett III, H. J. Sofia, D. L. Daniels, and F. R. Blattner. 1995. Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes. Nucleic Acids Res. 23:2105-2119.
16. Burman, L. G., J. Raichler, and J. T. Park. 1983. Evidence for diffuse growth of the cylindrical portion of the Escherichia coli murein sacculus. J. Bacteriol. 155:983-988.
17. Chahboune, A., M. Decaffmeyer, R. Brasseur, and B. Joris. 2005. Membrane topology of the Escherichia coli AmpG permease required for recycling of cell wall anhydromuropeptides and AmpC β-lactamase induction. Antimicrob. Agents Chemother. 49:1145-1149.
18. Chaloupka, J., and M. Strnadová. 1972. Turnover of murein in a diaminopimelic acid dependent mutant of Escherichia coli. Folia Microbiol. (Prague) 17:446-455.
19. Chaput, C., and I. G. Boneca. 2007. Peptidoglycan detection by mammals and flies. Microbes Infect. 9:637-647.
20. Cheng, Q., H. Li, K. Merdek, and J. T. Park. 2000. Molecular characterization of the β-N-acetylglucosaminidase of Escherichia coli and its role in cell wall recycling. J. Bacteriol. 182:4836- 4840.
21. Cheng, Q., and J. T. Park. 2002. Substrate specificity of the AmpG permease required for recycling of cell wall anhydro-muropeptides. J. Bacteriol. 184:6434-6436.
22. Chitlaru, E., and S. Roseman. 1996. Molecular cloning and characterization of a novel β-N-acetyl-D-glucosaminidase from Vibrio furnissii. J. Biol. Chem. 271:33433-33439.
23. Cloud-Hansen, K. A., S. B. Peterson, E. V. Stabb, W. E. Goldman, M. J. McFall-Ngai, and J. Handelsman. 2006. Breaching the great wall: peptidoglycan and microbial interactions. Nat. Rev. Microbiol. 4:710-716.
24. Cookson, B. T., H. L. Cho, L. A. Herwaldt, and W. E. Goldman. 1989. Biological activities and chemical composition of purified tracheal cytotoxin of Bordetella pertussis. Infect. Immun. 57:2223-2229.
25. Cooper, S., M. L. Hsieh, and B. Guenther. 1988. Mode of peptidoglycan synthesis in Salmonella typhimurium: single-strand insertion. J. Bacteriol. 170:3509-3512.
26. Dahl, U., T. Jaeger, B. T. Nguyen, J. M. Sattler, and C. Mayer. 2004. Identification of a phosphotransferase system of Escherichia coli required for growth on N-acetylmuramic acid. J. Bacteriol. 186:2385-2392.
27. de Jonge, B. L., F. B. Wientjes, I. Jurida, F. Driehuis, J. T. Wouters, and N. Nanninga. 1989. Peptidoglycan synthesis during the cell cycle of Escherichia coli: composition and mode of insertion. J. Bacteriol. 171:5783-5794.
28. de Pedro, M. A., W. D. Donachie, J. V. Höltje, and H. Schwarz. 2001. Constitutive septal murein synthesis in Escherichia coli with impaired activity of the morphogenetic proteins RodA and penicillin-binding protein 2. J. Bacteriol. 183:4115-4126.
29. de Pedro, M. A., J. C. Quintela, J. V. Höltje, and H. Schwarz. 1997. Murein segregation in Escherichia coli. J. Bacteriol. 179:2823-2834.
30. Dietz, H., D. Pfeifle, and B. Wiedemann. 1997. The signal molecule for β-lactamase induction in Enterobacter cloacae is the anhydromuramyl-pentapeptide. Antimicrob. Agents Chemother. 41:2113-2120.
31. Dijkstra, A. J., and W. Keck. 1996. Peptidoglycan as a barrier to transenvelope transport. J. Bacteriol. 178:5555-5562.
32. Garnier, M., M. J. Vacheron, M. Guinand, and G. Michel. 1985. Purification and partial characterization of the extracellular γ-D-glutamy -(L)meso-diaminopimelate endopeptidase I, from Bacillus sphaericus NCTC 9602. Eur. J. Biochem. 148:539-543.
33. Généreux, C., D. Dehareng, B. Devreese, J. Van Beeumen, J. M. Frère, and B. Joris. 2004. Mutational analysis of the catalytic centre of the Citrobacter freundii AmpD N-acetylmuramyl-L-alanine amidase. Biochem. J. 377:111-120.
34. Gitai, Z., N. A. Dye, A. Reisenauer, M. Wachi, and L. Shapiro. 2005. MreB actin-mediated segregation of a specific region of a bacterial chromosome. Cell 120:329-341.
35. Glauner, B. 1988. Separation and quantification of muropeptides with high-performance liquid chromatography. Anal. Biochem. 172:451-464.
36. Gomez, M. J., and A. A. Neyfakh. 2006. Genes involved in intrinsic antibiotic resistance of Acinetobacter baylyi. Antimicrob. Agents Chemother. 50:3562-3567.
37. Goodell, E. W. 1985. Recycling of murein by Escherichia coli. J. Bacteriol. 163:305-310.
38. Goodell, E. W., M. Fazio, and A. Tomasz. 1978. Effect of benzylpenicillin on the synthesis and structure of the cell envelope of Neisseria gonorrhoeae. Antimicrob. Agents Chemother. 13:514-526.
39. Goodell, E. W., and C. F. Higgins. 1987. Uptake of cell wall peptides by Salmonella typhimurium and Escherichia coli. J. Bacteriol. 169:3861-3865.
40. Goodell, E. W., and U. Schwarz. 1985. Release of cell wall peptides into culture medium by exponentially growing Escherichia coli. J. Bacteriol. 162:391-397.
41. Groisman, E. A., C. Parra-Lopez, M. Salcedo, C. J. Lipps, and F. Heffron. 1992. Resistance to host antimicrobial peptides is necessary for Salmonella virulence. Proc. Natl. Acad. Sci. USA 89:11939-11943.
42. Gulick, A. M., D. M. Schmidt, J. A. Gerlt, and I. Rayment. 2001. Evolution of enzymatic activities in the enolase superfamily: crystal structures of the L-Ala-D/L-Glu epimerases from Escherichia coli and Bacillus subtilis. Biochemistry 40:15716-15724.
43. Hebeler, B. H., and F. E. Young. 1976. Chemical composition and turnover of peptidoglycan in Neisseria gonorrhoeae. J. Bacteriol. 126:1180-1185.
44. Heidrich, C., M. F. Templin, A. Ursinus, M. Merdanovic, J. Berger, H. Schwarz, M. A. de Pedro, and J. V. Höltje. 2001. Involvement of N-acetylmuramyl-L-alanine amidases in cell separation and antibiotic-induced autolysis of Escherichia coli. Mol. Microbiol. 41:167-178.
45. Heidrich, C., A. Ursinus, J. Berger, H. Schwarz, and J. V. Höltje. 2002. Effects of multiple deletions of murein hydrolases on viability, septum cleavage, and sensitivity to large toxic molecules in Escherichia coli. J. Bacteriol. 184:6093-6099.
46. Hervé, M., A. Boniface, S. Gobec, D. Blanot, and D. Mengin-Lecreulx. 2007. Biochemical characterization and physiological properties of Escherichia coli UDP-N-acetylmuramate:L-alanyl- γ-D-glutamyl-meso-diaminopimelate ligase. J. Bacteriol. 189:3987-3995.
47. Höltje, J. V. 1998. Growth of the stress-bearing and shape-maintaining murein sacculus of Escherichia coli. Microbiol. Mol. Biol. Rev. 62:181-203.
48. Höltje, J. V., U. Kopp, A. Ursinus, and B. Wiedemann. 1994. The negative regulator of β-lactamase induction AmpD is a N-acetyl-anhydromuramyl-L-alanine amidase. FEMS Microbiol. Lett. 122:159-164.
49. Höltje, J. V., D. Mirelman, N. Sharon, and U. Schwarz. 1975. Novel type of murein transglycosylase in Escherichia coli. J. Bacteriol. 124:1067-1076.
50. Honoré, N., M. H. Nicolas, and S. T. Cole. 1989. Regulation of enterobacterial cephalosporinase production: the role of a membrane-bound sensory transducer. Mol. Microbiol. 3:1121-1130.
51. Hourdou, M. L., M. Guinand, M. J. Vacheron, G. Michel, L. Denoroy, C. Duez, S. Englebert, B. Joris, G. Weber, and J. M. Ghuysen. 1993. Characterization of the sporulation-related γ-D-glutamyl-(L)meso- diamino pimelic-acid-hydrolysing peptidase I of Bacillus sphaericus NCTC 9602 as a member of the metallo(zinc) carboxypeptidase A family. Modular design of the protein. Biochem. J. 292:563-570.
52. Hrebenda, J. 1979. Mutants of Escherichia coli with altered level of β-N-acetylglucosaminidase activities. Acta Microbiol. Pol. 28:53-62.
53. Ishino, F., W. Park, S. Tomioka, S. Tamaki, I. Takase, K. Kunugita, H. Matsuzawa, S. Asoh, T. Ohta, B. G. Spratt, and M. Matsuhashi. 1986. Peptidoglycan synthetic activities in membranes of Escherichia coli caused by overproduction of penicillin-binding protein 2 and RodA protein. J. Biol. Chem. 261:7024-7031.
54. Ishino, F., S. Tamaki, B. G. Spratt, and M. Matsuhashi. 1982. A mecillinam-sensitive peptidoglycan crosslinking reaction in Escherichia coli. Biochem. Biophys. Res. Commun. 109:689-696.
55. Iwai, N., K. Nagai, and M. Wachi. 2002. Novel S-benzylisothiourea compound that induces spherical cells in Escherichia coli probably by acting on a rod-shape-determining protein(s) other than penicillin-binding protein 2. Biosci. Biotechnol. Biochem. 66:2658-2662.
56. Jacobs, C., J. M. Frère, and S. Normark. 1997. Cytosolic intermediates for cell wall biosynthesis and degradation control inducible β-lactam resistance in gram-negative bacteria. Cell 88:823-832.
57. Jacobs, C., L. J. Huang, E. Bartowsky, S. Normark, and J. T. Park. 1994. Bacterial cell wall recycling provides cytosolic muropeptides as effectors for β-lactamase induction. EMBO J. 13:4684-4694.
58. Jacobs, C., B. Joris, M. Jamin, K. Klarsov, J. Van Beeumen, D. Mengin-Lecreulx, J. van Heijenoort, J. T. Park, S. Normark, and J. M. Frère. 1995. AmpD, essential for both β-lactamase regulation and cell wall recycling, is a novel cytosolic N-acetylmuramyl-L-alanine amidase. Mol. Microbiol. 15:553-559.
59. Jaeger, T., M. Arsic, and C. Mayer. 2005. Scission of the lactyl ether bond of N-acetylmuramic acid by Escherichia coli "etherase". J. Biol. Chem. 280:30100-30106.
60. Juan, C., M. D. Maciá, O. Gutierrez, C. Vidal, J. L. Pérez, and A. Oliver. 2005. Molecular mechanisms of β-lactam resistance mediated by AmpC hyperproduction in Pseudomonas aeruginosa clinical strains. Antimicrob. Agents Chemother. 49:4733-4738.
61. Juan, C., B. Moya, J. L. Pérez, and A. Oliver. 2006. Stepwise upregulation of the Pseudomonas aeruginosa chromosomal cephalosporinase conferring high-level β-lactam resistance involves three AmpD homologues. Antimicrob. Agents Chemother. 50:1780-1787.
62. Juncker, A. S., H. Willenbrock, G. Von Heijne, S. Brunak, H. Nielsen, and A. Krogh. 2003. Prediction of lipoprotein signal peptides in gram-negative bacteria. Protein Sci. 12:1652-1662.
63. Karczmarek, A., R. M. Baselga, S. Alexeeva, F. G. Hansen, M. Vicente, N. Nanninga, and T. den Blaauwen. 2007. DNA and origin region segregation are not affected by the transition from rod to sphere after inhibition of Escherichia coli MreB by A22. Mol. Microbiol. 65:51-63.
64. Klenchin, V. A., D. M. Schmidt, J. A. Gerlt, and I. Rayment. 2004. Evolution of enzymatic activities in the enolase superfamily: structure of a substrate-liganded complex of the L-Ala-D/L-Glu epimerase from Bacillus subtilis. Biochemistry 43:10370-10378.
65. Kong, K. F., S. R. Jayawardena, S. D. Indulkar, A. Del Puerto, C. L. Koh, N. Høiby, and K. Mathee. 2005. Pseudomonas aeruginosa AmpR is a global transcriptional factor that regulates expression of AmpC and PoxB β-lactamases, proteases, quorum sensing, and other virulence factors. Antimicrob. Agents Chemother. 49:4567-4575.
66. Koraimann, G. 2003. Lytic transglycosylases in macromolecular transport systems of gram-negative bacteria. Cell. Mol. Life Sci. 60:2371-2388.
67. Korfmann, G., and C. C. Sanders. 1989. ampG is essential for high-level expression of AmpC β-lactamase in Enterobacter cloacae. Antimicrob. Agents Chemother. 33:1946-1951.
68. Korza, H. J., and M. Bochtler. 2005. Pseudomonas aeruginosa LD-carboxypeptidase, a serine peptidase with a Ser-His-Glu triad and a nucleophilic elbow. J. Biol. Chem. 280:40802-40812.
69. Kraft, A. R., J. Prabhu, A. Ursinus, and J. V. Höltje. 1999. Interference with murein turnover has no effect on growth but reduces β-lactamase induction in Escherichia coli. J. Bacteriol. 181:7192-7198.
70. Létolfé, S., P. Delepelaire, and C. Wandersman. 2006. The housekeeping dipeptide permease is the Escherichia coli heme transporter and functions with two optional peptide binding proteins. Proc. Natl. Acad. Sci. USA 103:12891-12896.
71. Li, H., and J. T. Park. 1999. The periplasmic murein peptide-binding protein MppA is a negative regulator of multiple antibiotic resistance in Escherichia coli. J. Bacteriol. 181:4842-4847.
72. Liepinsh, E., C. Généreux, D. Dehareng, B. Joris, and G. Otting. 2003. NMR structure of Citrobacter freundii AmpD, comparison with bacteriophage T7 lysozyme and homology with PGRP domains. J. Mol. Biol. 327:833-842.
73. Liger, D., A. Masson, D. Blanot, J. van Heijenoort, and C. Parquet. 1995. Over-production, purification and properties of the uridine-diphosphate-N-acetylmuramate:L-alanine ligase from Escherichia coli. Eur. J. Biochem. 230:80-87.
74. Lindberg, F., S. Lindquist, and S. Normark. 1987. Inactivation of the ampD gene causes semiconstitutive overproduction of the inducible Citrobacter freundii β-lactamase. J. Bacteriol. 169:1923- 1928.
75. Lindquist, S., M. Galleni, F. Lindberg, and S. Normark. 1989. Signalling proteins in enterobacterial AmpC β-lactamase regulation. Mol. Microbiol. 3:1091-1102.
76. Lindquist, S., K. Weston-Hafer, H. Schmidt, C. Pul, G. Korfmann, J. Erickson, C. Sanders, H. H. Martin, and S. Normark. 1993. AmpG, a signal transducer in chromosomal β-lactamase induction. Mol. Microbiol. 9:703-715.
77. Mauck, J., L. Chan, and L. Glaser. 1971. Turnover of the cell wall of gram-positive bacteria. J. Biol. Chem. 246:1820-1827.
78. Meberg, B. M., A. L. Paulson, R. Priyadarshini, and K. D. Young. 2004. Endopeptidase penicillin-binding proteins 4 and 7 play auxiliary roles in determining uniform morphology of Escherichia coli. J. Bacteriol. 186: 8326-8336.
79. Mengin-Lecreulx, D., B. Flouret, and J. van Heijenoort. 1982. Cytoplasmic steps of peptidoglycan synthesis in Escherichia coli. J. Bacteriol. 151:1109-1117.
80. Mengin-Lecreulx, D., and J. van Heijenoort. 1996. Characterization of the essential gene glmM encoding phosphoglucosamine mutase in Escherichia coli. J. Biol. Chem. 271:32-39.
81. Mengin-Lecreulx, D., and J. van Heijenoort. 1994. Copurification of glucosamine-1-phosphate acetyltransferase and N-acetylglucosamine-1- phosphate uridyltransferase activities of Escherichia coli: characterization of the glmU gene product as a bifunctional enzyme catalyzing two subsequent steps in the pathway for UDP-N-acetylglucosamine synthesis. J. Bacteriol. 176:5788-5795.
82. Mengin-Lecreulx, D., and J. van Heijenoort. 1993. Identification of the glmU gene encoding N-acetylglucosamine-1-phosphate uridyltransferase in Escherichia coli. J. Bacteriol. 175:6150- 6157.
83. Mengin-Lecreulx, D., J. van Heijenoort, and J. T. Park. 1996. Identification of the mpl gene encoding UDP-N-acetylmuramate:L- alanyl-γ-D-glutamyl-meso-diaminopimelate ligase in Escherichia coli and its role in recycling of cell wall peptidoglycan. J. Bacteriol. 178:5347-5352.
84. Mielcarek, N., A. S. Debrie, D. Raze, J. Quatannens, J. Engle, W. E. Goldman, and C. Locht. 2006. Attenuated Bordetella pertussis: new live vaccines for intranasal immunisation. Vaccine 24:S2-54-55.
85. Nikaido, H. 1996. Outer membrane, p.29-47. In F. C. Neidhardt, R. Curtiss III, J. L. Ingraham, E. C. C. Lin, K. B. Low, B. Magasanik, W. S. Reznikoff, M. Riley, M. Schaechter, and H. E. Umbarger (ed.), Escherichia coli and Salmonella typhimurium: cellular and molecular biology, 2nd ed., vol. 2. American Society for Microbiology, Washington, DC.
86. Normark, S., H. G. Boman, and G. D. Bloom. 1971. Cell division in a chain-forming envA mutant of Escherichia coli K12. Fine structure of division sites and effects of EDTA, lysozyme and ampicillin. Acta Pathol. Microbiol. Scand. B Microbiol. Immunol. 79:651-664.
87. Normark, S., H. G. Boman, and E. Matsson. 1969. Mutant of Escherichia coli with anomalous cell division and ability to decrease episomally and chromosomally mediated resistance to ampicillin and several other antibiotics. J. Bacteriol. 97:1334-1342.
88. Núñez, C., S. Moreno, L. Cárdenas, G. Sóberon-Chávez, and G. Espín. 2000. Inactivation of the ampDE operon increases transcription of algD and affects morphology and encystment of Azotobacter vinelandii. J. Bacteriol. 182:4829-4835.
89. Park, J. T. 1993. An overview of the assembly, turnover, and recycling of the murein sacculus, p. 119-126. In M. A. de Pedro et al. (ed.), Bacterial growth and lysis. Plenum Press, New York, NY.
90. Park, J. T. 2001. Identification of a dedicated recycling pathway for anhydro-N-acetylmuramic acid and N-acetylglucosamine derived from Escherichia coli cell wall murein. J. Bacteriol. 183:3842-3847.
91. Park, J. T. 1996. The murein sacculus, p. 48-57. In F. C. Neidhardt, R. Curtiss III, J. L. Ingraham, E. C. C. Lin, K. B. Low, B. Magasanik, W. S. Reznikoff, M. Riley, M. Schaechter, and H. E. Umbarger (ed.), Escherichia coli and Salmonella typhimurium: cellular and molecular biology, 2nd ed., vol. 2. American Society for Microbiology, Washington, DC.
92. Park, J. T. 1993. Turnover and recycling of the murein sacculus in oligopeptide permease-negative strains of Escherichia coli: indirect evidence for an alternative permease system and for a monolayered sacculus. J. Bacteriol. 175:7-11.
93. Park, J. T. 1995. Why does Escherichia coli recycle its cell wall peptides? Mol. Microbiol. 17:421-426.
94. Park, J. T., D. Raychaudhuri, H. Li, S. Normark, and D. Mengin-Lecreulx. 1998. MppA, a periplasmic binding protein essential for import of the bacterial cell wall peptide L-alanyl-γ-D-glutamyl-meso- diaminopimelate. J. Bacteriol. 180:1215-1223.
95. Parquet, C., B. Flouret, M. Leduc, Y. Hirota, and J. van Heijenoort. 1983. N-Acetylmuramoyl-L-alanine amidase of Escherichia coli K12. Possible physiological functions. Eur. J. Biochem. 133:371-377.
96. Parra-Lopez, C., R. Lin, A. Aspedon, and E. A. Groisman. 1994. A Salmonella protein that is required for resistance to antimicrobial peptides and transport of potassium. EMBO J. 13:3964-3972.
97. Pearce, S. R., M. L. Mimmack, M. P. Gallagher, U. Gileadi, S. C. Hyde, and C. F. Higgins. 1992. Membrane topology of the integral membrane components, OppB and OppC, of the oligopeptide permease of Salmonella typhimurium. Mol. Microbiol. 6:47-57.
98. Popham, D. L., and K. D. Young. 2003. Role of penicillin-binding proteins in bacterial cell morphogenesis. Curr. Opin. Microbiol. 6:594-599.
99. Priyadarshini, R., M. A. de Pedro, and K. D. Young. 2007. Role of peptidoglycan amidases in the development and morphology of the division septum in Escherichia coli. J. Bacteriol. 189:5334-5347.
100. Priyadarshini, R., D. L. Popham, and K. D. Young. 2006. Daughter cell separation by penicillin-binding proteins and peptidoglycan amidases in Escherichia coli. J. Bacteriol. 188:5345-5355.
101. Rosenthal, R. S., W. Nogami, B. T. Cookson, W. E. Goldman, and W. J. Folkening. 1987. Major fragment of soluble peptidoglycan released from growing Bordetella pertussis is tracheal cytotoxin. Infect. Immun. 55:2117-2120.
102. Scheurwater, E., C. W. Reid, and A. J. Clarke. 30 March 2007, posting date. Lytic transglycosylases: bacterial space-making autolysins. Int. J. Biochem. Cell Biol. doi:10.1016/j.biocel.2007.03.018.
103. Schiefner, A., K. Gerber, S. Seitz, W. Welte, K. Diederichs, and W. Boos. 2005. The crystal structure of Mlc, a global regulator of sugar metabolism in Escherichia coli. J. Biol. Chem. 280:29073-29079.
104. Schleifer, K. H., and O. Kandler. 1972. Peptidoglycan types of bacterial cell walls and their taxonomic implications. Bacteriol. Rev. 36:407-477.
105. Schmidt, D. M., B. K. Hubbard, and J. A. Gerlt. 2001. Evolution of enzymatic activities in the enolase superfamily: functional assignment of unknown proteins in Bacillus subtilis and Escherichia coli as L-Ala-D/L-Glu epimerases. Biochemistry 40:15707-15715.
106. Shockman, G. D., and J. V. Höltje. 1994. Microbial peptidoglycan (murein) hydrolases, p. 131-166. In J.-M. Ghuysen and R. Hakenbeck (ed.), Bacterial cell wall, vol. 27. Elsevier Science B.V., Amsterdam, The Netherlands.
107. Schroeder, U., B. Henrich, J. Fink, and R. Plapp. 1994. Peptidase D of Escherichia coli K-12, a metallopeptidasc of low substrate specificity. FEMS Microbiol. Lett. 123:153-159.
108. Serror, P., and A. L. Sonenshein. 1996. Interaction of CcdY, a novel Bacillus subtilis DNA-binding protein, with the dpp promoter region. Mol. Microbiol. 20:843-852.
109. Sinha, R. K., and R. S. Rosenthal. 1980. Release of soluble peptidoglycan from growing conococci: demonstration of anhydro-muramyl- containing fragments. Infect. Immun. 29:914-925.
110. Slack, F. J., P. Serror, E. Joyce, and A. L. Sonenshein. 1995. A gene required for nutritional repression of the Bacillus subtilis dipeptide permease operon. Mol. Microbiol. 15:689-702.
111. Spratt, B. G., and A. B. Pardee. 1975. Penicillin-binding proteins and cell shape in E. coli. Nature 254:516-517.
112. Stubbs, K. A., M. Balcewich, B. L. Mark, and D. J. Vocadlo. 2007. Small molecule inhibitors of a glycoside hydrolase attenuate inducible AmpC mediated β-lactam resistance. J. Biol. Chem. 282:21382-21391.
113. Sun, D., S. Cohen, N. Mani, C. Murphy, and D. M. Rothstein. 2002. A pathway-specific cell based screening system to detect bacteial cell wall inhibitors. J. Antibiot. (Tokyo) 55:279-287.
114. Talukder, A. A., S. Yanai, T. Nitta, A. Kato, and M. Yamada. 1996. RpoS-dependent regulation of genes expressed at late stationary phase in Escherichia coli. FEBS Lett. 386:177-180.
115. Templin, M. F., A. Ursinus, and J. V. Höltje. 1999. A defee in cell wall recycling triggers autolysis during the stationary growth phase of Escherichia coli. EMBO J. 18:4108-4117.
116. Teplyakov, A., C. Leriche, G. Obmolova, B. Badet, and M. A. Badet-Denisot. 2002. From Lobry de Bruyn to enzyme-catalyzed ammonia channelling: molecular studies of D-glucosamine-6P synthase. Nat Prod. Rep. 19:60-69.
117. Tokuda, H., and S. Matsuyama. 2004. Sorting of lipoproteins to the outer membrane in E. coli. Biochim. Biophys. Acta 1693:5-13.
118. Uehara, T., and J. T. Park. 2007. An anhydro-N-acetylmuramyl-L-alanine amidase with broad specificity tethered to the outer membrane of Escherichia coli. J. Bacteriol. 189:5634-5641.
119. Uehara, T., and J. T. Park. 2008. Growth of Escherichia coli: significance of peptidoglycan degradation during elongation and septation. J. Bacteriol. 190:3914-3922.
120. Uehara, T., and J. T. Park. 2003. Identification of MpaA, an amidase in Escherichia coli that hydrolyzes the γ-D-glutamyl- meso-diaminopimelate bond in murein peptides. J. Bacteriol. 185:679-682.
121. Uehara, T., and J. T. Park. 2004. The N-acetyl-D- glucosamine kinase of Escherichia coli and its role in murein recycling. J. Bacteriol. 186:7273-7279.
122. Uehara, T., K. Suefuji, T. Jaeger, C. Mayer, and J. T. Park. 2006. MurQ etherase is required by Escherichia coli in order to metabolize anhydro-N-acetylmuramic acid obtained either from the environment or from its own cell wall. J. Bacteriol. 188:1660-1662.
123. Uehara, T., K. Suefuji, N. Valbuena, B. Meehan, M. Donegan, and J. T. Park. 2005. Recycling of the anhydro-N-acetylmuramic acid derived from cell wall murein involves a two-step conversion to N-acetylglucosamine-phosphate. J. Bacteriol. 187:3643-3649.
124. Ursinus, A., H. Steinhaus, and J. V. Höltje. 1992. Purification of a nocardicin A-sensitive LD-carboxypeptidase from Escherichia coli by affinity chromatography. J. Bacteriol. 174:441-446.
125. Varma, A., and K. D. Young. 2004. FtsZ collaborates with penicillin binding proteins to generate bacterial cell shape in Escherichia coli. J. Bacteriol. 186:6768-6774.
126. Vega, D., and J. A. Ayala. 2006. The DD-carboxypeptidase activity encoded by pbp4B is not essential for the cell growth of Escherichia coli. Arch. Microbiol. 185:23-27.
127. Viala, J., C. Chaput, I. G. Boneca, A. Cardona, S. E. Girardin, A. P. Moran, R. Athman, S. Memet, M. R. Huerre, A. J. Coyle, P. S. DiStefano, P. J. Sansonetti, A. Labigne, J. Bertin, D. J. Philpott, and R. L. Ferrero. 2004. Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island. Nat. Immunol. 5:1166-1174.
128. Vötsch, W., and M. F. Templin. 2000. Characterization of a β-N-acetylglucosaminidase of Escherichia coli and elucidation of its role in muropeptide recycling and β-lactamase induction. J. Biol. Chem. 275:39032-39038.
129. White, R. J. 1968. Control of amino sugar metabolism in Escherichia coli and isolation of mutants unable to degrade amino sugars. Biochem. J. 106:847-858.
130. White, R. J., and C. A. Pasternak. 1967. The purification and properties of N-acetylglucosamine 6-phosphate deacetylase from Escherichia coli. Biochem. J. 105:121-125.
131. Yem, D. W., and H. C. Wu. 1976. Isolation of Escherichia coli K-12 mutants with altered level of β-N- acetylglucosaminidase. J. Bacteriol. 125:372-373.
132. Yem, D. W., and H. C. Wu. 1976. Purification and properties of β-N-acetylglucosaminidase from Escherichia coli. J. Bacteriol. 125:324-331.
133. Young, K. D. 2003. Bacterial shape. Mol. Microbiol. 49:571-580.
134. Zahrl, D., M. Wagner, K. Bischof, M. Bayer, B. Zavecz, A. Beranek, C. Ruckenstuhl, G. E. Zarfel, and G. Koraimann. 2005. Peptidoglycan degradation by specialized lytic transglycosylases associated with type III and type IV secretion systems. Microbiology 151:3455-3467.
135. Zhuang, X., and H. Zhang. 2002. Identification, characterization of levoglucosan kinase, and cloning and expression of levoglucosan kinase cDNA from Aspergillus niger CBX-209 in Escherichia coli. Protein Expr. Purif. 26:71-81.