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Volumn 2, Issue 11, 2012, Pages 985-994

Measuring oncogenic signaling pathways in cancer with PET: An emerging paradigm from studies in castration-resistant prostate cancer

Author keywords

[No Author keywords available]

Indexed keywords

16BETA FLUORO 5ALPHA DIHYDROTESTOSTERONE F 18; ABIRATERONE ACETATE; ANDROSTANOLONE; CA 125 ANTIGEN; CARBONATE DEHYDRATASE IX; CARCINOEMBRYONIC ANTIGEN; ENZALUTAMIDE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; HEAT SHOCK PROTEIN 90 INHIBITOR; KALLIKREIN; MEDRONATE TECHNETIUM TC 99M; MONOCLONAL ANTIBODY 5A10; MONOCLONAL ANTIBODY J591; MYC PROTEIN; PROSTATE SPECIFIC ANTIGEN; PROSTATE SPECIFIC MEMBRANE ANTIGEN; RADIOISOTOPE; RADIOPHARMACEUTICAL AGENT; SMALL INTERFERING RNA; SODIUM FLUORIDE F 18; TRACER; TRANSFERRIN; TRANSFERRIN RECEPTOR; TRASTUZUMAB; UNCLASSIFIED DRUG; ZIRCONIUM;

EID: 84869998375     PISSN: 21598274     EISSN: 21598290     Source Type: Journal    
DOI: 10.1158/2159-8290.CD-12-0178     Document Type: Review
Times cited : (17)

References (75)
  • 1
    • 60749096036 scopus 로고    scopus 로고
    • Surrogate and mediating endpoints: Current status and future directions
    • Prentice RL. Surrogate and mediating endpoints: current status and future directions. J Natl Cancer Inst 2009; 101: 216-217.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 216-217
    • Prentice, R.L.1
  • 2
    • 33845974419 scopus 로고    scopus 로고
    • Biomarkers and surrogate end points for fit-for-purpose development and regulatory evaluation of new drugs
    • Wagner JA, Williams SA, Webster CJ. Biomarkers and surrogate end points for fit-for-purpose development and regulatory evaluation of new drugs. Clin Pharmacol Ther 2007; 81: 104-107.
    • (2007) Clin Pharmacol Ther , vol.81 , pp. 104-107
    • Wagner, J.A.1    Williams, S.A.2    Webster, C.J.3
  • 3
    • 33644675811 scopus 로고    scopus 로고
    • Biology of progressive, castration-resistant prostate cancer: Directed therapies targeting the androgen-receptor signaling axis
    • Scher HI, Sawyers CL. Biology of progressive, castration-resistant prostate cancer: directed therapies targeting the androgen-receptor signaling axis. J Clin Oncol 2005; 23: 8253-8261.
    • (2005) J Clin Oncol , vol.23 , pp. 8253-8261
    • Scher, H.I.1    Sawyers, C.L.2
  • 6
    • 27844506524 scopus 로고    scopus 로고
    • Akt-regulated pathways in prostate cancer
    • Majumder PK, Sellers WR. Akt-regulated pathways in prostate cancer. Oncogene 2005; 24: 7465-7474.
    • (2005) Oncogene , vol.24 , pp. 7465-7474
    • Majumder, P.K.1    Sellers, W.R.2
  • 7
    • 70349395222 scopus 로고    scopus 로고
    • Anti-androgens and androgen-depleting therapies in prostate cancer: New agents for an established target
    • Chen Y, Clegg NJ, Scher HI. Anti-androgens and androgen-depleting therapies in prostate cancer: new agents for an established target. Lancet Oncol 2009; 10: 981-991.
    • (2009) Lancet Oncol , vol.10 , pp. 981-991
    • Chen, Y.1    Clegg, N.J.2    Scher, H.I.3
  • 8
    • 68049137909 scopus 로고    scopus 로고
    • Targeting the PI3K/AKT pathway for the treatment of prostate cancer
    • Sarker D, Reid AH, Yap TA, de Bono JS. Targeting the PI3K/AKT pathway for the treatment of prostate cancer. Clin Cancer Res 2009; 15: 4799-4805.
    • (2009) Clin Cancer Res , vol.15 , pp. 4799-4805
    • Sarker, D.1    Reid, A.H.2    Yap, T.A.3    de Bono, J.S.4
  • 10
    • 77952105685 scopus 로고    scopus 로고
    • Antitumour activity of MDV3100 in castration-resistant prostate cancer: A phase 1-2 study
    • Scher HI, Beer TM, Higano CS, Anand A, Taplin ME, Efstathiou E, et al. Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1-2 study. Lancet 2010; 375: 1437-1446.
    • (2010) Lancet , vol.375 , pp. 1437-1446
    • Scher, H.I.1    Beer, T.M.2    Higano, C.S.3    Anand, A.4    Taplin, M.E.5    Efstathiou, E.6
  • 12
    • 41949104346 scopus 로고    scopus 로고
    • Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: Recommendations of the Prostate Cancer Clinical Trials Working Group
    • Scher HI, Halabi S, Tannock I, Morris M, Sternberg CN, Carducci MA, et al. Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group. J Clin Oncol 2008; 26: 1148-1159.
    • (2008) J Clin Oncol , vol.26 , pp. 1148-1159
    • Scher, H.I.1    Halabi, S.2    Tannock, I.3    Morris, M.4    Sternberg, C.N.5    Carducci, M.A.6
  • 13
    • 33746187320 scopus 로고    scopus 로고
    • The detection of bone metastases in patients with high-risk prostate cancer: 99mTc-MDP Planar bone scintigraphy, single- and multifi eld-of-view SPECT, 18F-fluoride PET, and 18F-fluoride PET/CT
    • E ven-Sapir E, Metser U, Mishani E, Lievshitz G, Lerman H, Leibovitch I. The detection of bone metastases in patients with high-risk prostate cancer: 99mTc-MDP Planar bone scintigraphy, single- and multifi eld-of-view SPECT, 18F-fluoride PET, and 18F-fluoride PET/CT. J Nucl Med 2006; 47: 287-97.
    • (2006) J Nucl Med , vol.47 , pp. 287-297
    • ven-Sapir, E.E.1    Metser, U.2    Mishani, E.3    Lievshitz, G.4    Lerman, H.5    Leibovitch, I.6
  • 14
    • 79957451082 scopus 로고    scopus 로고
    • Developing imaging strategies for castration resistant prostate cancer
    • Fox JJ, Morris MJ, Larson SM, Schoder H, Scher HI. Developing imaging strategies for castration resistant prostate cancer. Acta Oncol 2011; 50 Suppl 1: 39-48.
    • (2011) Acta Oncol , vol.50 , Issue.SUPPL 1 , pp. 39-48
    • Fox, J.J.1    Morris, M.J.2    Larson, S.M.3    Schoder, H.4    Scher, H.I.5
  • 17
    • 84871205365 scopus 로고    scopus 로고
    • Available from: www.biomarkersconsortium.org.
  • 19
    • 84863746052 scopus 로고    scopus 로고
    • Marked, homogeneous, and early [18F] Fluorodeoxyglucose-positron emission tomography responses to vemurafenib in BRAF-mutant Advanced Melanoma
    • McArthur GA, Puzanov I, Amaravadi R, Ribas A, Chapman P, Kim KB, et al. Marked, homogeneous, and early [18F] Fluorodeoxyglucose-positron emission tomography responses to vemurafenib in BRAF-mutant Advanced Melanoma. J Clin Oncol 2012; 30: 1628-1634.
    • (2012) J Clin Oncol , vol.30 , pp. 1628-1634
    • McArthur, G.A.1    Puzanov, I.2    Amaravadi, R.3    Ribas, A.4    Chapman, P.5    Kim, K.B.6
  • 20
    • 66149108022 scopus 로고    scopus 로고
    • Monitoring predominantly cytostatic treatment response with 18F-FDG PET
    • Contractor KB, Aboagye EO. Monitoring predominantly cytostatic treatment response with 18F-FDG PET. J Nucl Med 2009; 50 Suppl 1: 97S-105S.
    • (2009) J Nucl Med , vol.50 , Issue.SUPPL. 1
    • Contractor, K.B.1    Aboagye, E.O.2
  • 21
    • 33947596928 scopus 로고    scopus 로고
    • Monitoring cancer treatment with PET/CT: Does it make a difference?
    • Weber WA, Figlin R. Monitoring cancer treatment with PET/CT: does it make a difference? J Nucl Med 2007; 48 Suppl 1: 36S-44S.
    • (2007) J Nucl Med , vol.48 , Issue.SUPPL 1
    • Weber, W.A.1    Figlin, R.2
  • 22
    • 37049013325 scopus 로고    scopus 로고
    • 3′-deoxy-3′-[18F]fluorothymidine positron emission tomography is a sensitive method for imaging the response of BRAF-dependent tumors to MEK inhibition
    • Solit DB, Santos E, Pratilas CA, Lobo J, Moroz M, Cai S, et al. 3′-deoxy-3′-[18F]fluorothymidine positron emission tomography is a sensitive method for imaging the response of BRAF-dependent tumors to MEK inhibition. Cancer Res 2007; 67: 11463-11469.
    • (2007) Cancer Res , vol.67 , pp. 11463-11469
    • Solit, D.B.1    Santos, E.2    Pratilas, C.A.3    Lobo, J.4    Moroz, M.5    Cai, S.6
  • 23
  • 24
    • 78649479373 scopus 로고    scopus 로고
    • Radiolabeled small molecule protein kinase inhibitors for imaging with PET or SPECT
    • Hicks JW, VanBrocklin HF, Wilson AA, Houle S, Vasdev N. Radiolabeled small molecule protein kinase inhibitors for imaging with PET or SPECT. Molecules 2010; 15: 8260-8278.
    • (2010) Molecules , vol.15 , pp. 8260-8278
    • Hicks, J.W.1    Vanbrocklin, H.F.2    Wilson, A.A.3    Houle, S.4    Vasdev, N.5
  • 26
    • 0029979129 scopus 로고    scopus 로고
    • Positron emission tomography with 2-[18F]Fluoro-2-deoxy-D-glucose and 16alpha-[18F]fluoro-17beta-estradiol in breast cancer: Correlation with estrogen receptor status and response to systemic therapy
    • Mortimer JE, Dehdashti F, Siegel BA, Katzenellenbogen JA, Fracasso P, Welch MJ. Positron emission tomography with 2-[18F]Fluoro-2-deoxy-D-glucose and 16alpha-[18F]fluoro-17beta-estradiol in breast cancer: correlation with estrogen receptor status and response to systemic therapy. Clin Cancer Res 1996; 2: 933-939.
    • (1996) Clin Cancer Res , vol.2 , pp. 933-939
    • Mortimer, J.E.1    Dehdashti, F.2    Siegel, B.A.3    Katzenellenbogen, J.A.4    Fracasso, P.5    Welch, M.J.6
  • 27
    • 79960428275 scopus 로고    scopus 로고
    • Fluoroestradiol positron emission tomography reveals differences in pharmacodynamics of aromatase inhibitors, tamoxifen, and fulvestrant in patients with metastatic breast cancer
    • Linden HM, Kurland BF, Peterson LM, Schubert EK, Gralow JR, Specht JM, et al. Fluoroestradiol positron emission tomography reveals differences in pharmacodynamics of aromatase inhibitors, tamoxifen, and fulvestrant in patients with metastatic breast cancer. Clin Cancer Res 2011; 17: 4799-4805.
    • (2011) Clin Cancer Res , vol.17 , pp. 4799-4805
    • Linden, H.M.1    Kurland, B.F.2    Peterson, L.M.3    Schubert, E.K.4    Gralow, J.R.5    Specht, J.M.6
  • 29
    • 66149085319 scopus 로고    scopus 로고
    • Noninvasive imaging of alphaVbeta3 function as a predictor of the antimigratory and antiproliferative effects of dasatinib
    • Dumont RA, Hildebrandt I, Su H, Haubner R, Reischl G, Czernin JG, et al. Noninvasive imaging of alphaVbeta3 function as a predictor of the antimigratory and antiproliferative effects of dasatinib. Cancer Res 2009; 69: 3173-3179.
    • (2009) Cancer Res , vol.69 , pp. 3173-3179
    • Dumont, R.A.1    Hildebrandt, I.2    Su, H.3    Haubner, R.4    Reischl, G.5    Czernin, J.G.6
  • 30
    • 80051700245 scopus 로고    scopus 로고
    • Novel (64)Cu- and (68)Ga-labeled RGD conjugates show improved PET imaging of alpha(nu)beta(3) integrin expression and facile radiosynthesis
    • Dumont RA, Deininger F, Haubner R, Maecke HR, Weber WA, Fani M. Novel (64)Cu- and (68)Ga-labeled RGD conjugates show improved PET imaging of alpha(nu)beta(3) integrin expression and facile radiosynthesis. J Nucl Med 2011; 52: 1276-1284.
    • (2011) J Nucl Med , vol.52 , pp. 1276-1284
    • Dumont, R.A.1    Deininger, F.2    Haubner, R.3    Maecke, H.R.4    Weber, W.A.5    Fani, M.6
  • 32
    • 0028946388 scopus 로고
    • Synthesis of 11 beta-[18F]fluoro-5 alpha-dihydrotestosterone and 11 beta-[18F]fluoro-19-nor-5 alpha-dihydrotestosterone: Preparation via halofluorination-reduction, receptor binding, and tissue distribution
    • Choe YS, Lidstrom PJ, Chi DY, Bonasera TA, Welch MJ, Katzenellenbogen JA. Synthesis of 11 beta-[18F]fluoro-5 alpha-dihydrotestosterone and 11 beta-[18F]fluoro-19-nor-5 alpha-dihydrotestosterone: preparation via halofluorination-reduction, receptor binding, and tissue distribution. J Med Chem 1995; 38: 816-825.
    • (1995) J Med Chem , vol.38 , pp. 816-825
    • Choe, Y.S.1    Lidstrom, P.J.2    Chi, D.Y.3    Bonasera, T.A.4    Welch, M.J.5    Katzenellenbogen, J.A.6
  • 33
    • 0030160448 scopus 로고    scopus 로고
    • Preclinical evaluation of fluorine-18-labeled androgen receptor ligands in baboons
    • Bonasera TA, O'Neil JP, Xu M, Dobkin JA, Cutler PD, Lich LL, et al. Preclinical evaluation of fluorine-18-labeled androgen receptor ligands in baboons. J Nucl Med 1996; 37: 1009-1015.
    • (1996) J Nucl Med , vol.37 , pp. 1009-1015
    • Bonasera, T.A.1    O'Neil, J.P.2    Xu, M.3    Dobkin, J.A.4    Cutler, P.D.5    Lich, L.L.6
  • 34
    • 75749116783 scopus 로고    scopus 로고
    • Pharmacokinetic assessment of the uptake of 16beta-18F-fluoro-5alpha-dihydrotestosterone (FDHT) in prostate tumors as measured by PET
    • Beattie BJ, Smith-Jones PM, Jhanwar YS, Schoder H, Schmidtlein CR, Morris MJ, et al. Pharmacokinetic assessment of the uptake of 16beta-18F-fluoro-5alpha-dihydrotestosterone (FDHT) in prostate tumors as measured by PET. J Nucl Med 2010; 51: 183-192.
    • (2010) J Nucl Med , vol.51 , pp. 183-192
    • Beattie, B.J.1    Smith-Jones, P.M.2    Jhanwar, Y.S.3    Schoder, H.4    Schmidtlein, C.R.5    Morris, M.J.6
  • 35
    • 2342599027 scopus 로고    scopus 로고
    • Tumor localization of 16beta-18F-fluoro-5alpha-dihydrotestosterone versus 18F-FDG in patients with progressive, metastatic prostate cancer
    • Larson SM, Morris M, Gunther I, Beattie B, Humm JL, Akhurst TA, et al. Tumor localization of 16beta-18F-fluoro-5alpha-dihydrotestosterone versus 18F-FDG in patients with progressive, metastatic prostate cancer. J Nucl Med 2004; 45: 366-373.
    • (2004) J Nucl Med , vol.45 , pp. 366-373
    • Larson, S.M.1    Morris, M.2    Gunther, I.3    Beattie, B.4    Humm, J.L.5    Akhurst, T.A.6
  • 36
    • 16544375295 scopus 로고    scopus 로고
    • PET-based radiation dosimetry in man of 18F-fluorodihydrotestosterone, a new radiotracer for imaging prostate cancer
    • Zanzonico PB, Finn R, Pentlow KS, Erdi Y, Beattie B, Akhurst T, et al. PET-based radiation dosimetry in man of 18F-fluorodihydrotestosterone, a new radiotracer for imaging prostate cancer. J Nucl Med 2004; 45: 1966-1971.
    • (2004) J Nucl Med , vol.45 , pp. 1966-1971
    • Zanzonico, P.B.1    Finn, R.2    Pentlow, K.S.3    Erdi, Y.4    Beattie, B.5    Akhurst, T.6
  • 37
    • 80455168438 scopus 로고    scopus 로고
    • Practical approach for comparative analysis of multilesion molecular imaging using a semiautomated program for PET/CT
    • Fox JJ, Autran-Blanc E, Morris MJ, Gavane S, Nehmeh S, Van Nuffel A, et al. Practical approach for comparative analysis of multilesion molecular imaging using a semiautomated program for PET/CT. J Nucl Med 2011; 52: 1727-1732.
    • (2011) J Nucl Med , vol.52 , pp. 1727-1732
    • Fox, J.J.1    Autran-Blanc, E.2    Morris, M.J.3    Gavane, S.4    Nehmeh, S.5    van Nuffel, A.6
  • 38
    • 0027203411 scopus 로고
    • Flutamide withdrawal syndrome: Its impact on clinical trials in hormone-refractory prostate cancer
    • Scher HI, Kelly WK. Flutamide withdrawal syndrome: its impact on clinical trials in hormone-refractory prostate cancer. J Clin Oncol 1993; 11: 1566-1572.
    • (1993) J Clin Oncol , vol.11 , pp. 1566-1572
    • Scher, H.I.1    Kelly, W.K.2
  • 39
    • 41149166182 scopus 로고    scopus 로고
    • Prostate-specific antigen and prostate cancer: Prediction, detection and monitoring
    • Lilja H, Ulmert D, Vickers AJ. Prostate-specific antigen and prostate cancer: prediction, detection and monitoring. Nat Rev Cancer 2008; 8: 268-278.
    • (2008) Nat Rev Cancer , vol.8 , pp. 268-278
    • Lilja, H.1    Ulmert, D.2    Vickers, A.J.3
  • 40
    • 74949139859 scopus 로고    scopus 로고
    • Prostate kallikrein markers in diagnosis, risk stratification and prognosis
    • Ulmert D, O'Brien MF, Bjartell AS, Lilja H. Prostate kallikrein markers in diagnosis, risk stratification and prognosis. Nat Rev Urol 2009; 6: 384-391.
    • (2009) Nat Rev Urol , vol.6 , pp. 384-391
    • Ulmert, D.1    O'Brien, M.F.2    Bjartell, A.S.3    Lilja, H.4
  • 41
    • 0033557320 scopus 로고    scopus 로고
    • Tissue PSA from fine-needle biopsies of prostatic carcinoma as related to serum PSA, clinical stage, cytological grade, and DNA ploidy
    • Stege RH, Tribukait B, Carlstrom KA, Grande M, Pousette AH. Tissue PSA from fine-needle biopsies of prostatic carcinoma as related to serum PSA, clinical stage, cytological grade, and DNA ploidy. Prostate 1999; 38: 183-188.
    • (1999) Prostate , vol.38 , pp. 183-188
    • Stege, R.H.1    Tribukait, B.2    Carlstrom, K.A.3    Grande, M.4    Pousette, A.H.5
  • 42
    • 0030219893 scopus 로고    scopus 로고
    • Upregulation of prostate-specific membrane antigen after androgen-deprivation therapy
    • Wright GL, Grob BM, Haley C, Grossman K, Newhall K, Petrylak D, et al. Upregulation of prostate-specific membrane antigen after androgen-deprivation therapy. Urology 1996; 48: 326-334.
    • (1996) Urology , vol.48 , pp. 326-334
    • Wright, G.L.1    Grob, B.M.2    Haley, C.3    Grossman, K.4    Newhall, K.5    Petrylak, D.6
  • 43
    • 0037138413 scopus 로고    scopus 로고
    • Upregulation of prostate specific membrane antigen/folate hydrolase transcription by an enhancer
    • Noss KR, Wolfe SA, Grimes SR. Upregulation of prostate specific membrane antigen/folate hydrolase transcription by an enhancer. Gene 2002; 285: 247-256.
    • (2002) Gene , vol.285 , pp. 247-256
    • Noss, K.R.1    Wolfe, S.A.2    Grimes, S.R.3
  • 44
    • 70149094319 scopus 로고    scopus 로고
    • Preclinical evaluation of novel glutamate-urea-lysine analogues that target prostate-specific membrane antigen as molecular imaging pharmaceuticals for prostate cancer
    • Hillier SM, Maresca KP, Femia FJ, Marquis JC, Foss CA, Nguyen N, et al. Preclinical evaluation of novel glutamate-urea-lysine analogues that target prostate-specific membrane antigen as molecular imaging pharmaceuticals for prostate cancer. Cancer Res 2009; 69: 6932-6940.
    • (2009) Cancer Res , vol.69 , pp. 6932-6940
    • Hillier, S.M.1    Maresca, K.P.2    Femia, F.J.3    Marquis, J.C.4    Foss, C.A.5    Nguyen, N.6
  • 45
    • 0035117123 scopus 로고    scopus 로고
    • PSMA specific antibodies and their diagnostic and therapeutic use
    • Holmes EH. PSMA specific antibodies and their diagnostic and therapeutic use. Expert Opin Investig Drugs 2001; 10: 511-519.
    • (2001) Expert Opin Investig Drugs , vol.10 , pp. 511-519
    • Holmes, E.H.1
  • 46
    • 0034665171 scopus 로고    scopus 로고
    • I n vitro characterization of radiolabeled monoclonal antibodies specific for the extracellular domain of prostatespecific membrane antigen
    • Smith-Jones PM, Vallabahajosula S, Goldsmith SJ, Navarro V, Hunter CJ, Bastidas D, et al. I n vitro characterization of radiolabeled monoclonal antibodies specific for the extracellular domain of prostatespecific membrane antigen. Cancer Res 2000; 60: 5237-5243.
    • (2000) Cancer Res , vol.60 , pp. 5237-5243
    • Smith-Jones, P.M.1    Vallabahajosula, S.2    Goldsmith, S.J.3    Navarro, V.4    Hunter, C.J.5    Bastidas, D.6
  • 47
    • 79959328548 scopus 로고    scopus 로고
    • Noninvasive measurement of androgen receptor signaling with a positron-emitting radiopharmaceutical that targets prostate-specific membrane antigen
    • Evans MJ, Smith-Jones PM, Wongvipat J, Navarro V, Kim S, Bander NH, et al. Noninvasive measurement of androgen receptor signaling with a positron-emitting radiopharmaceutical that targets prostate-specific membrane antigen. Proc Natl Acad Sci U S A 2011; 108: 9578-9582.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 9578-9582
    • Evans, M.J.1    Smith-Jones, P.M.2    Wongvipat, J.3    Navarro, V.4    Kim, S.5    Bander, N.H.6
  • 48
    • 0141919750 scopus 로고    scopus 로고
    • Targeting metastatic prostate cancer with radiolabeled monoclonal antibody J591 to the extracellular domain of prostate specific membrane antigen
    • Bander NH, Trabulsi EJ, Kostakoglu L, Yao D, Vallabhajosula S, Smith-Jones P, et al. Targeting metastatic prostate cancer with radiolabeled monoclonal antibody J591 to the extracellular domain of prostate specific membrane antigen. J Urol 2003; 170: 1717-21.
    • (2003) J Urol , vol.170 , pp. 1717-1721
    • Bander, N.H.1    Trabulsi, E.J.2    Kostakoglu, L.3    Yao, D.4    Vallabhajosula, S.5    Smith-Jones, P.6
  • 50
    • 84866146188 scopus 로고    scopus 로고
    • Imaging androgen receptor signaling with a radiotracer targeting free prostate specific antigen
    • Ulmert D, Evans MJ, Holland JP, Rice SL, Wongvipat J, Pettersson K, et al. Imaging androgen receptor signaling with a radiotracer targeting free prostate specific antigen. Cancer Discov 2012; 2: 320-327.
    • (2012) Cancer Discov , vol.2 , pp. 320-327
    • Ulmert, D.1    Evans, M.J.2    Holland, J.P.3    Rice, S.L.4    Wongvipat, J.5    Pettersson, K.6
  • 51
    • 0037658635 scopus 로고    scopus 로고
    • Limitations to the use of the CA-125 antigen level in ovarian cancer
    • Markman M. Limitations to the use of the CA-125 antigen level in ovarian cancer. Curr Oncol Rep 2003; 5: 263-264.
    • (2003) Curr Oncol Rep , vol.5 , pp. 263-264
    • Markman, M.1
  • 52
    • 0035059972 scopus 로고    scopus 로고
    • Carcinoembryonic antigen as a marker for colorectal cancer: Is it clinically useful?
    • Duffy MJ. Carcinoembryonic antigen as a marker for colorectal cancer: is it clinically useful? Clin Chem 2001; 47: 624-30.
    • (2001) Clin Chem , vol.47 , pp. 624-630
    • Duffy, M.J.1
  • 53
    • 78649636616 scopus 로고    scopus 로고
    • Carbonic anhydrase 9 in clear cell renal cell carcinoma: A marker for diagnosis, prognosis and treatment
    • Tostain J, Li G, Gentil-Perret A, Gigante M. Carbonic anhydrase 9 in clear cell renal cell carcinoma: a marker for diagnosis, prognosis and treatment. Eur J Cancer 2010; 46: 3141-3148.
    • (2010) Eur J Cancer , vol.46 , pp. 3141-3148
    • Tostain, J.1    Li, G.2    Gentil-Perret, A.3    Gigante, M.4
  • 54
    • 0031059179 scopus 로고    scopus 로고
    • Detection of c-myc oncogene amplification and chromosomal anomalies in metastatic prostatic carcinoma by fluorescence in situ hybridization
    • Jenkins RB, Qian J, Lieber MM, Bostwick DG. Detection of c-myc oncogene amplification and chromosomal anomalies in metastatic prostatic carcinoma by fluorescence in situ hybridization. Cancer Res 1997; 57: 524-531.
    • (1997) Cancer Res , vol.57 , pp. 524-531
    • Jenkins, R.B.1    Qian, J.2    Lieber, M.M.3    Bostwick, D.G.4
  • 55
    • 50249133616 scopus 로고    scopus 로고
    • Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis
    • Gurel B, Iwata T, Koh CM, Jenkins RB, Lan F, Van Dang C, et al. Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis. Mod Pathol 2008; 21: 1156-1167.
    • (2008) Mod Pathol , vol.21 , pp. 1156-1167
    • Gurel, B.1    Iwata, T.2    Koh, C.M.3    Jenkins, R.B.4    Lan, F.5    van Dang, C.6
  • 57
    • 84870289201 scopus 로고    scopus 로고
    • Annotating MYC oncogene status with 89 Zr-transferrin
    • 2012 Sep 23. doi: 10.1038/nm.2935. [Epub ahead of print]
    • Holland JP, Evans MJ, Rice SL, Wongvipat J, Sawyers CL, Lewis JS. Annotating MYC oncogene status with 89 Zr-transferrin. Nat Med 2012 Sep 23. doi: 10.1038/nm.2935. [Epub ahead of print].
    • Nat Med
    • Holland, J.P.1    Evans, M.J.2    Rice, S.L.3    Wongvipat, J.4    Sawyers, C.L.5    Lewis, J.S.6
  • 58
    • 33644770587 scopus 로고    scopus 로고
    • Activation of transferrin receptor 1 by c-Myc enhances cellular proliferation and tumorigenesis
    • O'Donnell KA, Yu D, Zeller KI, Kim JW, Racke F, Thomas-Tikhonenko A, et al. Activation of transferrin receptor 1 by c-Myc enhances cellular proliferation and tumorigenesis. Mol Cell Biol 2006; 26: 2373-2386.
    • (2006) Mol Cell Biol , vol.26 , pp. 2373-2386
    • O'Donnell, K.A.1    Yu, D.2    Zeller, K.I.3    Kim, J.W.4    Racke, F.5    Thomas-Tikhonenko, A.6
  • 59
    • 0032878831 scopus 로고    scopus 로고
    • Targeting of transferrin receptors in nude mice bearing A431 and LS174T xenografts with [18F]holo-transferrin: Permeability and receptor dependence
    • Aloj L, Jogoda E, Lang L, Caraco C, Neumann RD, Sung C, et al. Targeting of transferrin receptors in nude mice bearing A431 and LS174T xenografts with [18F]holo-transferrin: permeability and receptor dependence. J Nucl Med 1999; 40: 1547-1555.
    • (1999) J Nucl Med , vol.40 , pp. 1547-1555
    • Aloj, L.1    Jogoda, E.2    Lang, L.3    Caraco, C.4    Neumann, R.D.5    Sung, C.6
  • 60
    • 19644364626 scopus 로고    scopus 로고
    • Preparation, biodistribution, and small animal PET of 45Ti-transferrin
    • Vavere AL, Welch MJ. Preparation, biodistribution, and small animal PET of 45Ti-transferrin. J Nucl Med 2005; 46: 683-690.
    • (2005) J Nucl Med , vol.46 , pp. 683-690
    • Vavere, A.L.1    Welch, M.J.2
  • 62
    • 80053527523 scopus 로고    scopus 로고
    • Targeting the internal epitope of prostate-specific membrane antigen with 89Zr-7E11 immuno-PET
    • Ruggiero A, Holland JP, Hudolin T, Shenker L, Koulova A, Bander NH, et al. Targeting the internal epitope of prostate-specific membrane antigen with 89Zr-7E11 immuno-PET. J Nucl Med 2011; 52: 1608-1615.
    • (2011) J Nucl Med , vol.52 , pp. 1608-1615
    • Ruggiero, A.1    Holland, J.P.2    Hudolin, T.3    Shenker, L.4    Koulova, A.5    Bander, N.H.6
  • 63
    • 77749309983 scopus 로고    scopus 로고
    • Measuring the pharmacodynamic effects of a novel Hsp90 inhibitor on HER2/neu expression in mice using Zr-DFOtrastuzumab
    • Holland JP, Caldas-Lopes E, Divilov V, Longo VA, Taldone T, Zatorska D, et al. Measuring the pharmacodynamic effects of a novel Hsp90 inhibitor on HER2/neu expression in mice using Zr-DFOtrastuzumab. PLoS One 2010; 5: e8859.
    • (2010) PLoS One , vol.5
    • Holland, J.P.1    Caldas-Lopes, E.2    Divilov, V.3    Longo, V.A.4    Taldone, T.5    Zatorska, D.6
  • 65
    • 28844470357 scopus 로고    scopus 로고
    • Context-dependent hormone-refractory progression revealed through characterization of a novel murine prostate cancer cell line
    • Watson PA, Ellwood-Yen K, King JC, Wongvipat J, Lebeau MM, Sawyers CL. Context-dependent hormone-refractory progression revealed through characterization of a novel murine prostate cancer cell line. Cancer Res 2005; 65: 11565-11571.
    • (2005) Cancer Res , vol.65 , pp. 11565-11571
    • Watson, P.A.1    Ellwood-Yen, K.2    King, J.C.3    Wongvipat, J.4    Lebeau, M.M.5    Sawyers, C.L.6
  • 67
    • 80052955256 scopus 로고    scopus 로고
    • BET bromodomain inhibition as a therapeutic strategy to target c-Myc
    • Delmore JE, Issa GC, Lemieux ME, Rahl PB, Shi J, Jacobs HM, et al. BET bromodomain inhibition as a therapeutic strategy to target c-Myc. Cell 2011; 146: 904-17.
    • (2011) Cell , vol.146 , pp. 904-917
    • Delmore, J.E.1    Issa, G.C.2    Lemieux, M.E.3    Rahl, P.B.4    Shi, J.5    Jacobs, H.M.6
  • 68
    • 80055000824 scopus 로고    scopus 로고
    • RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
    • Zuber J, Shi J, Wang E, Rappaport AR, Herrmann H, Sison EA, et al. RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature 2011; 478: 524-528.
    • (2011) Nature , vol.478 , pp. 524-528
    • Zuber, J.1    Shi, J.2    Wang, E.3    Rappaport, A.R.4    Herrmann, H.5    Sison, E.A.6
  • 70
    • 79960954452 scopus 로고    scopus 로고
    • 18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers
    • Palaskas N, Larson SM, Schultz N, Komisopoulou E, Wong J, Rohle D, et al. 18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers. Cancer Res 2011; 71: 5164-5174.
    • (2011) Cancer Res , vol.71 , pp. 5164-5174
    • Palaskas, N.1    Larson, S.M.2    Schultz, N.3    Komisopoulou, E.4    Wong, J.5    Rohle, D.6
  • 72
    • 67650758019 scopus 로고    scopus 로고
    • Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer
    • Wang Q, Li W, Zhang Y, Yuan X, Xu K, Yu J, et al. Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. Cell 2009; 138: 245-256.
    • (2009) Cell , vol.138 , pp. 245-256
    • Wang, Q.1    Li, W.2    Zhang, Y.3    Yuan, X.4    Xu, K.5    Yu, J.6
  • 73
    • 0032905924 scopus 로고    scopus 로고
    • C-Myc target genes involved in cell growth, apoptosis, and metabolism
    • Dang CV. C-Myc target genes involved in cell growth, apoptosis, and metabolism. Mol Cell Biol 1999; 19: 1-11.
    • (1999) Mol Cell Biol , vol.19 , pp. 1-11
    • Dang, C.V.1
  • 74
    • 41649102043 scopus 로고    scopus 로고
    • The cancer biomarker problem
    • Sawyers CL. The cancer biomarker problem. Nature 2008; 452: 548-552.
    • (2008) Nature , vol.452 , pp. 548-552
    • Sawyers, C.L.1
  • 75
    • 79959269553 scopus 로고    scopus 로고
    • Circulating tumor cells as biomarkers in prostate cancer
    • Danila DC, Fleisher M, Scher HI. Circulating tumor cells as biomarkers in prostate cancer. Clin Cancer Res 2011; 17: 3903-3912.
    • (2011) Clin Cancer Res , vol.17 , pp. 3903-3912
    • Danila, D.C.1    Fleisher, M.2    Scher, H.I.3


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