Whey protein before and during resistance exercise has no effect on muscle mass and strength in untrained young adults

International Journal of Sport Nutrition and Exercise Metabolism

Volumn 22, Issue 6, 2012, Pages 463-469

  Weisgarber, Krissy D ^a   Candow, Darren G ^a   Vogt, Emelie S M ^a  

^a UNIVERSITY OF REGINA   (Canada)

Author keywords

Bolus; Dosing; Protein source; Timing

Indexed keywords

ALANINE; ARGININE; ASPARTIC ACID; CYSTEINE; GLUTAMINE; GLYCINE; HISTIDINE; ISOLEUCINE; LEUCINE; LYSINE; MALTODEXTRIN; METHIONINE; MUSCLE PROTEIN; PEPTIDES AND PROTEINS; PHENYLALANINE; PROLINE; SERINE; STARCH; SUCROSE; THREONINE; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG; VALINE; WHEY PROTEIN;

ADULT; AMINO ACID COMPOSITION; ARTICLE; BODY COMPOSITION; BODY MASS; BONE MINERAL; CALORIC INTAKE; CARBOHYDRATE INTAKE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DIETARY INTAKE; DUAL ENERGY X RAY ABSORPTIOMETRY; EXTENSOR MUSCLE; FAT INTAKE; FEMALE; FLEXOR MUSCLE; HUMAN; HUMAN EXPERIMENT; INGESTION; LEAN BODY WEIGHT; MACRONUTRIENT; MALE; MUSCLE CONTRACTION; MUSCLE MASS; MUSCLE STRENGTH; NORMAL HUMAN; NUTRITIONAL ASSESSMENT; PHYSICAL ACTIVITY; POTENTIAL DIFFERENCE; PROTEIN DEGRADATION; PROTEIN INTAKE; PROTEIN SYNTHESIS; RANDOMIZED CONTROLLED TRIAL; RESISTANCE TRAINING; ADVERSE EFFECTS; BEVERAGE; DIET; DIETARY SUPPLEMENT; DOUBLE BLIND PROCEDURE; ECHOGRAPHY; MEDICAL RECORD; MUSCLE DEVELOPMENT; NUTRITION; PHOTON ABSORPTIOMETRY; SKELETAL MUSCLE; YOUNG ADULT;

ABSORPTIOMETRY, PHOTON; ADULT; BEVERAGES; DIET; DIET RECORDS; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MUSCLE DEVELOPMENT; MUSCLE STRENGTH; MUSCLE, SKELETAL; RESISTANCE TRAINING; SPORTS NUTRITIONAL PHYSIOLOGICAL PHENOMENA; WHEY PROTEINS; YOUNG ADULT;

EID: 84869988978     PISSN: 1526484X     EISSN: 15432742     Source Type: Journal    
DOI: 10.1123/ijsnem.22.6.463     Document Type: Article

References (22)

1. Beelen, M., Koopman, R., Gijsen, A.P., Vandereyt, H., Kies, A.K., Kuipers, H., . . . van Loon, L.J. (2008). Protein coingestion stimulates muscle protein synthesis during resistance-type exercise. American Journal of Physiology. Endocrinology and Metabolism, 295(1), E70-E77. PubMed doi:10.1152/ajpendo.00774.2007
2. Borsheim, E., Tipton, K.D., Wolf, S.E., & Wolfe, R.R. (2002). Essential amino acids and muscle protein recovery from resistance exercise. American Journal of Physiology. Endocrinology and Metabolism, 283(4), E648-E657. PubMed
3. Burd, N.A., Tang, J.E., Moore, D.R., & Phillips, S.M. (2009). Exercise training and protein metabolism: Influences of contraction, protein intake, and sex-based differences. Journal of Applied Physiology, 106(5), 1692-1701. PubMed doi:10.1152/japplphysiol.91351.2008
4. Burd, N.A., West, D.W., Moore, D.R., Atherton, P.J., Staples, A.W., Prior, T., . . . Wagenmakers, A.J. (2011). Enhanced amino acid sensitivity of myofibrillar protein synthesis persists for up to 24 h after resistance exercise in young men. The Journal of Nutrition, 141(4), 568-573. PubMed doi:10.3945/jn.110.135038
5. Candow, D.G., Burke, N.C., Smith-Palmer, T., & Burke, D.G. (2006). Effect of whey and soy protein supplementation combined with resistance training in young adults. International Journal of Sport Nutrition and Exercise Metabolism, 16(3), 233-244. PubMed (Pubitemid 43953295)
6. Candow, D.G., & Chilibeck, P.D. (2005). Differences in size, strength, and power of upper and lower body muscle groups in young and older men. Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 60(2), 148-156. PubMed doi:10.1093/gerona/60.2.148
7. Candow, D.G., Chilibeck, P.D., Burke, D.G., Mueller, K.D., & Lewis, J.D. (2011). Effect of different frequencies of creatine supplementation on muscle size and strength in young adults. Journal of Strength and Conditioning Research, 25(7), 1831-1838. PubMed doi:10.1519/JSC.0b013e3181e7419a
8. Candow, D.G., Chilibeck, P.D., Facci, M., Abeysekara, S., & Zello, G.A. (2006). Protein supplementation before and after resistance training in older men. European Journal of Applied Physiology, 97(5), 548-556. PubMed doi:10.1007/s00421-006-0223-8
9. Godin, G., & Shephard, R.J. (1985). A simple method to assess exercise behavior in the community. Canadian Journal of Applied Sport Sciences, 10(3), 141-146. PubMed
10. Ha, E., & Zemel, M.B. (2003). Functional properties of whey, whey components, and essential amino acids: Mechanisms underlying health benefits for active people (review). The Journal of Nutritional Biochemistry, 14(5), 251-258. PubMed doi:10.1016/S0955-2863(03)00030-5
11. Karlsson, H.K., Nilsson, P.A., Nilsson, J., Chibalin, A.V., Zierath, J.R., & Blomstrand, E. (2004). Branched-chain amino acids increase p70S6k phosphorylation in human skeletal muscle after resistance exercise. American Journal of Physiology. Endocrinology and Metabolism, 287(1), E1-E7. PubMed doi:10.1152/ajpendo.00430.2003
12. Kimball, S.R., Farrell, P.A., & Jefferson, L.S. (2002). Invited review: Role of insulin in translational control of protein synthesis in skeletal muscle by amino acids or exercise. Journal of Applied Physiology, 93(3), 1168-1180. PubMed (Pubitemid 34919691)
13. Koopman, R., Pannemans, D.L., Jeukendrup, A.E., Gijsen, A.P., Senden, J.M., Halliday, D., . . . Wagenmakers, A.J. (2004). Combined ingestion of protein and carbohydrate improves protein balance during ultra-endurance exercise. American Journal of Physiology. Endocrinology and Metabolism, 287(4), E712-E720. PubMed doi:10.1152/ajpendo.00543.2003
14. Koopman, R., Pennings, B., Zorenc, A.H., & van Loon, L.J. (2007). Protein ingestion further augments S6K1 phosphorylation in skeletal muscle following resistance type exercise in males. The Journal of Nutrition, 137(8), 1880-1886. PubMed (Pubitemid 47292734)
15. Miller, B.F., Olesen, J.L., Hansen, M., Døssing, S., Crameri, R.M., Welling, R.J., . . . Rennie, M.J. (2005). Coordinated collagen and muscle protein synthesis in human patella tendon and quadriceps muscle after exercise. Journal of Physiology, 567(Pt. 3), 1021-1033. (Pubitemid 41387842)
16. Pennings, B., Boirie, Y., Senden, J.M., Gijsen, A.P., Kuipers, H., & van Loon, L.J. (2011). Whey protein stimulates postprandial muscle protein accretion more effectively than do casein and casein hydrolysate in older men. The American Journal of Clinical Nutrition, 93(5), 997-1005. PubMed doi:10.3945/ajcn.110.008102
17. Phillips, S.M., Hartman, J.W., & Wilkinson, S.B. (2005). Dietary protein to support anabolism with resistance exercise in young men. Journal of the American College of Nutrition, 24(2), 134S-139S. PubMed (Pubitemid 40489659)
18. Staples, A.W., Burd, N.A., West, D.W., Currie, K.D., Atherton, P.J., Moore, D.R., . . . Phillips, S.M. (2011). Carbohydrate does not augment exercise-induced protein accretion versus protein alone. Medicine and Science in Sports and Exercise, 43(7), 1154-1161. PubMed doi:10.1249/MSS.0b013e31820751cb
19. Tang, J.E., Moore, D.R., Kujbida, G.W., Tarnopolsky, M.A., & Phillips, S.M. (2009). Ingestion of whey hydrolysate, casein, or soy protein isolate: Effects on mixed muscle protein synthesis at rest and following resistance exercise in young men. Journal of Applied Physiology, 107(3), 987-992. PubMed doi:10.1152/japplphysiol.00076.2009
20. Tipton, K.D., Elliott, T.A., Cree, M.G., Aarsland, A.A., Sanford, A.P., & Wolfe, R.R. (2007). Stimulation of net muscle protein synthesis by whey protein ingestion before and after exercise. American Journal of Physiology. Endocrinology and Metabolism, 292(1), E71-E76. PubMed doi:10.1152/ajpendo.00166. 2006
21. Tipton, K.D., Rasmussen, B.B., Miller, S.L., Wolf, S.E., Owens-Stovall, S.K., Petrini, B.E., & Wolfe, R.R. (2001). Timing of amino acid-carbohydrate ingestion alters anabolic response of muscle to resistance exercise. American Journal of Physiology. Endocrinology and Metabolism, 281(2), E197-E206. PubMed
22. West, D.W., Burd, N.A., Coffey, V.G., Baker, S.K., Burke, L.M., Hawley, J.A., . . . Phillips, S.M. (2011). Rapid aminoacidemia enhances myofibrillar protein synthesis and anabolic intramuscular signaling responses after resistance exercise. The American Journal of Clinical Nutrition, 94(3), 795-803. PubMed doi:10.3945/ajcn.111.013722