Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environments

Biotechnology and Bioengineering

Volumn 110, Issue 1, 2013, Pages 220-228

  Grünberger, Alexander ^a   van Ooyen, Jan ^a   Paczia, Nicole ^a   Rohe, Peter ^a   Schiendzielorz, Georg ^a   Eggeling, Lothar ^a   Wiechert, Wolfgang ^a   Kohlheyer, Dietrich ^a   Noack, Stephan ^a  

^a FORSCHUNGSZENTRUM JÜLICH   (Germany)

Author keywords

Acetate; C. glutamicum; Growth rate; Microfluidics; Single cell

Indexed keywords

BATCH CELL CULTURE; BYPRODUCTS; GLUCOSE; MICROFLUIDICS; VOLATILE FATTY ACIDS;

ACETATE; BATCH CULTIVATION; BATCH CULTURE; C. GLUTAMICUM; CELL-FREE; CORYNEBACTERIUM GLUTAMICUM; DIFFERENT SCALE; LOW CONCENTRATIONS; PERFUSION SYSTEM; PRODUCTION PROCESS; QUANTIFICATION METHODS; SHAKE-FLASK CULTURES; SINGLE CELLS;

GROWTH RATE;

ACETIC ACID; GLUCOSE;

ARTICLE; BACTERIAL GROWTH; BACTERIUM CULTURE; BIOMASS; CELL DENSITY; CELL FREE SYSTEM; CONTROLLED STUDY; CORYNEBACTERIUM GLUTAMICUM; GROWTH RATE; MICROFLUIDICS; NONHUMAN;

CORYNEBACTERIUM GLUTAMICUM;

EID: 84869889713     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24616     Document Type: Article

References (28)

1. Bäumchen C, Knoll A, Husemann B, Seletzky J, Maier B, Dietrich C, Amoabediny G, Büchs J. 2007. Effect of elevated dissolved carbon dioxide concentrations on growth of Corynebacterium glutamicum on D-glucose and L-lactate. J Biotechnol 128(4): 868-874.
2. Eggeling L, Bott M. 2005. Handbook of Corynebacterium glutamicum. Boca Raton, Florida: CRC Press, Tailor and Francis Group.
3. Feist AM, Zielinski DC, Orth JD, Schellenberger J, Herrgard MJ, Palsson B. 2010. Model-driven evaluation of the production potential for growth-coupled products of Escherichia coli Metab Eng 12(3): 173-186.
4. Fong SS, Palsson B. 2004. Metabolic gene-deletion strains of Escherichia coli evolve to computationally predicted growth phenotypes. Nat Genet 36(10): 1056-1058.
5. Groisman A, Lobo C, Cho H, Campbell JK, Dufour YS, Stevens AM, Levchenko A. 2005. A microfluidic chemostat for experiments with bacterial and yeast cells. Nat Methods 2(9): 685-689.
6. Grünberger A, Paczia N, Probst C, Schendzielorz G, Eggeling L, Noack S, Wiechert W, Kohlheyer D. 2012. A disposable picoliter bioreactor for cultivation and investigation of industrially relevant bacteria on single cell level. Lab Chip 12(11): 2060-2068.
7. Guillouet S, Engasser JM. 1996. Kinetics of volume variation of Corynebacterium glutamicum following saline osmotic upshifts. Biotechnol Lett 18(2): 145-148.
8. Han SO, Inui M, Yukawa H. 2008. Effect of carbon source availability and growth phase on expression of Corynebacterium glutamicum genes involved in the tricarboxylic acid cycle and glyoxylate bypass. Microbiology 154(Pt 10): 3073-3083.
9. Kensy F, Zang E, Faulhammer C, Tan RK, Büchs J. 2009. Validation of a high-throughput fermentation system based on online monitoring of biomass and fluorescence in continuously shaken microtiter plates. Microb Cell Fact 8: 31.
10. Khanna S, Srivastava AK. 2005. Statistical media optimization studies for growth and PHB production by Ralstonia eutropha. Process Biochemistry 40(6): 2173-2182.
11. Kortmann H, Chasanis P, Blank LM, Franzke J, Kenig EY, Schmid A. 2009. The Envirostat-A new bioreactor concept. Lab Chip 9(4): 576-585.
12. Lara AR, Galindo E, Ramírez OT, Palomares LA. 2006. Living with heterogeneities in bioreactors: Understanding the effects of environmental gradients on cells. Mol Biotechnol 34(3): 355-381.
13. Lee KS, Boccazzi P, Sinskey AJ, Ram RJ. 2011. Microfluidic chemostat and turbidostat with flow rate, oxygen, and temperature control for dynamic continuous culture. Lab Chip 11(10): 1730-1739.
14. Litsanov B, Kabus A, Brocker M, Bott M. 2012. Efficient aerobic succinate production from glucose in minimal medium with Corynebacterium glutamicum. Microb Biotechnol 5(1): 116-128.
15. Luli GW, Strohl WR. 1990. Comparison of growth, acetate production, and acetate inhibition of Escherichia coli strains in batch and fed-batch fermentations. Appl Environ Microbiol 56(4): 1004-1011.
16. Mandenius CF, Brundin A. 2008. Bioprocess optimization using design-of-experiments methodology. Biotechnol Prog 24(6): 1191-1203.
17. Monod J. 1949. The growth of bacterial cultures. Annu Rev Microbiol 3: 371-394.
18. Petelenz-Kurdziel E, Eriksson E, Smedh M, Beck C, Hohmann S, Goksör M. 2011. Quantification of cell volume changes upon hyperosmotic stress in Saccharomyces cerevisiae. Integr Biol (Camb) 3(11): 1120-1126.
19. San KY, Bennett GN, Aristidou AA, Chou CH. 1994. Strategies in high-level expression of recombinant protein in Escherichia coli Ann NY Acad Sci 721: 257-267.
20. Shin HS, Kim YJ, Yoo IH, Lee HS, Jin S, Ha UH. 2011. Autoinduction of a genetic locus encoding putative acyltransferase in Corynebacterium glutamicum. Biotechnol Lett 33(1): 97-102.
21. Sisignano M, Morbitzer D, Gätgens J, Oldiges M, Soppa J. 2010. A 2-oxoacid dehydrogenase complex of Haloferax volcanii is essential for growth on isoleucine but not on other branched-chain amino acids. Microbiology 156(Pt 2): 521-529.
22. Suresh S, Srivastava VC, Mishra IM. 2009. Critical analysis of engineering aspects of shaken flask bioreactors. Crit Rev Biotechnol 29(4): 255-278.
23. Takors R. 2011. Scale-up of microbial processes: Impacts, tools and open questions. J Biotechnol
24. Volkmer B, Heinemann M. 2011. Condition-dependent cell volume and concentration of Escherichia coli to facilitate data conversion for systems biology modeling. PLoS ONE 6(7): e 23126.
25. Wang P, Robert L, Pelletier J, Dang WL, Taddei F, Wright A, Jun S. 2010. Robust growth of Escherichia coli Curr Biol 20(12): 1099-1103.
26. Wendisch VF, de Graaf AA, Sahm H, Eikmanns BJ. 2000. Quantitative determination of metabolic fluxes during coutilization of two carbon sources: Comparative analyses with Corynebacterium glutamicum during growth on acetate and/or glucose. J Bacteriol 182(11): 3088-3096.
27. Wiechert W, Noack S. 2011. Mechanistic pathway modeling for industrial biotechnology: Challenging but worthwhile. Curr Opin Biotechnol 22(5): 604-610.
28. Zhang YH. 2010. Production of biocommodities and bioelectricity by cell-free synthetic enzymatic pathway biotransformations: Challenges and opportunities. Biotechnol Bioeng 105(4): 663-677.