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Volumn 19, Issue 6, 2012, Pages 512-519

Clinical update on screening, diagnosis and management of metabolic disorders and cardiovascular risk factors associated with polycystic ovary syndrome

Author keywords

cardiovascular disease; dyslipidemia; insulin resistance; metabolic syndrome; obesity; polycystic ovary syndrome

Indexed keywords

CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CHROMOSOME 2; DEEND1A GENE; DYSLIPIDEMIA; ENVIRONMENTAL FACTOR; GENE; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; HUMAN; INSULIN RESISTANCE; LHCGR GENE; METABOLIC DISORDER; METABOLIC SYNDROME X; NON INSULIN DEPENDENT DIABETES MELLITUS; NONALCOHOLIC FATTY LIVER; OBESITY; OVARY POLYCYSTIC DISEASE; PHENOTYPE; REVIEW;

EID: 84869889537     PISSN: 1752296X     EISSN: 17522978     Source Type: Journal    
DOI: 10.1097/MED.0b013e32835a000e     Document Type: Review
Times cited : (26)

References (76)
  • 1
    • 2942642477 scopus 로고    scopus 로고
    • The prevalence and features of the polycystic ovary syndrome in an unselected population
    • Azziz R, Woods KS, Reyna R, et al. The prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab 2004; 89:2745-2749.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 2745-2749
    • Azziz, R.1    Woods, K.S.2    Reyna, R.3
  • 2
    • 74549160893 scopus 로고    scopus 로고
    • The prevalence of polycystic ovary syndrome in a community sample assessed under contrasting diagnostic criteria
    • March WA, Moore VM, Willson KJ, et al. The prevalence of polycystic ovary syndrome in a community sample assessed under contrasting diagnostic criteria. Hum Reprod 2010; 25:544-551.
    • (2010) Hum Reprod , vol.25 , pp. 544-551
    • March, W.A.1    Moore, V.M.2    Willson, K.J.3
  • 3
    • 0029095150 scopus 로고
    • Polycystic ovary syndrome
    • Franks S. Polycystic ovary syndrome. N Engl J Med 1995; 333:853-861.
    • (1995) N Engl J Med , vol.333 , pp. 853-861
    • Franks, S.1
  • 4
    • 0141998792 scopus 로고    scopus 로고
    • Polycystic ovary syndrome: Syndrome XX?
    • Sam S, Dunaif A. Polycystic ovary syndrome: syndrome XX? Trends Endocrinol Metab 2003; 14:365-370.
    • (2003) Trends Endocrinol Metab , vol.14 , pp. 365-370
    • Sam, S.1    Dunaif, A.2
  • 5
    • 84864854916 scopus 로고    scopus 로고
    • Age associated differences in prevalence of individual rotterdam criteria and metabolic risk factors during reproductive age in 446 Caucasian women with polycystic ovary syndrome
    • In Press
    • Glintborg D, Mumm H, Ravn P, et al. Age associated differences in prevalence of individual rotterdam criteria and metabolic risk factors during reproductive age in 446 Caucasian women with polycystic ovary syndrome. Horm Metab Res 2012; In Press.
    • (2012) Horm Metab Res
    • Glintborg, D.1    Mumm, H.2    Ravn, P.3
  • 6
    • 58849159714 scopus 로고    scopus 로고
    • An association between nonalcoholic fatty liver disease and polycystic ovarian syndrome
    • Brzozowska MM, Ostapowicz G, Weltman MD. An association between nonalcoholic fatty liver disease and polycystic ovarian syndrome. J Gastroenterol Hepatol 2009; 24:243-247.
    • (2009) J Gastroenterol Hepatol , vol.24 , pp. 243-247
    • Brzozowska, M.M.1    Ostapowicz, G.2    Weltman, M.D.3
  • 7
    • 0001217801 scopus 로고
    • Diagnostic criteria for polycystic ovary syndrome
    • Dunaif A Givens JR Haseltine F editors Boston MA: Blackwell Scientific
    • Zawadski, JK, Dunaif A. Diagnostic criteria for polycystic ovary syndrome. In: Dunaif A, Givens JR, Haseltine F, editors. Polycystic ovary syndrome. Boston, MA: Blackwell Scientific; 1992. pp. 377-384.
    • (1992) Polycystic Ovary Syndrome , pp. 377-384
    • Zawadski, J.K.1    Dunaif, A.2
  • 8
    • 0346725827 scopus 로고    scopus 로고
    • Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome
    • Rotterdam EA-SPCWG. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril 2004; 81:19-25.
    • (2004) Fertil Steril , vol.81 , pp. 19-25
    • Rotterdam, E.A.-S.P.C.W.G.1
  • 9
    • 33751526500 scopus 로고    scopus 로고
    • Positions statement: Criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: An Androgen Excess Society guideline
    • Azziz R, Carmina E, Dewailly D, et al. Positions statement: criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: an Androgen Excess Society guideline. J Clin Endocrinol Metab 2006; 91:4237-4245.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 4237-4245
    • Azziz, R.1    Carmina, E.2    Dewailly, D.3
  • 10
    • 84861978898 scopus 로고    scopus 로고
    • Relative Contributions of oligomenorrhea and hyperandrogenemia to the risk of metabolic syndrome in midlife women
    • Polotsky AJ, Allshouse A, Crawford SL, et al. Relative Contributions of oligomenorrhea and hyperandrogenemia to the risk of metabolic syndrome in midlife women. J Clin Endocrinol Metab 2012; 97:E868-E877.
    • (2012) J Clin Endocrinol Metab , vol.97
    • Polotsky, A.J.1    Allshouse, A.2    Crawford, S.L.3
  • 11
    • 79953069240 scopus 로고    scopus 로고
    • Polycystic ovary syndrome: Etiology, pathogenesis and diagnosis
    • Goodarzi MO, Dumesic DA, Chazenbalk G, et al. Polycystic ovary syndrome: etiology, pathogenesis and diagnosis. Nat Rev Endocrinol 2011; 7:219-231.
    • (2011) Nat Rev Endocrinol , vol.7 , pp. 219-231
    • Goodarzi, M.O.1    Dumesic, D.A.2    Chazenbalk, G.3
  • 12
    • 18744381558 scopus 로고    scopus 로고
    • American Association of Clinical Endocrinologists position statement on metabolic and cardiovascular consequences of polycystic ovary syndrome
    • American Association of Clinical Endocrinologists Polycystic Ovary Syndrome Writing Committee
    • American Association of Clinical Endocrinologists Polycystic Ovary Syndrome Writing Committee. American Association of Clinical Endocrinologists position statement on metabolic and cardiovascular consequences of polycystic ovary syndrome. Endocr Pract 2005; 11:126-134.
    • (2005) Endocr Pract , vol.11 , pp. 126-134
  • 13
    • 59349098805 scopus 로고    scopus 로고
    • The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: The complete task force report
    • Azziz R, Carmina E, Dewailly D, et al. The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report. Fertil Steril 2009; 91:456-488.
    • (2009) Fertil Steril , vol.91 , pp. 456-488
    • Azziz, R.1    Carmina, E.2    Dewailly, D.3
  • 14
    • 0346186090 scopus 로고    scopus 로고
    • Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS)
    • Rotterdam ESHRE/ASRM-Sponsored PCOS consensus workshop group
    • Rotterdam ESHRE/ASRM-Sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod 2004; 19:41-47.
    • (2004) Hum Reprod , vol.19 , pp. 41-47
  • 15
    • 77952787136 scopus 로고    scopus 로고
    • Assessment of cardiovascular risk and prevention of cardiovascular disease in women with the polycystic ovary syndrome: A consensus statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society
    • Wild RA, Carmina E, Diamanti-Kandarakis E, et al. Assessment of cardiovascular risk and prevention of cardiovascular disease in women with the polycystic ovary syndrome: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society. J Clin Endocrinol Metab 2010; 95:2038-2049.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 2038-2049
    • Wild, R.A.1    Carmina, E.2    Diamanti-Kandarakis, E.3
  • 16
    • 0942265414 scopus 로고    scopus 로고
    • Detecting insulin resistance in polycystic ovary syndrome: Purposes and pitfalls
    • Legro RS, Castracane VD, Kauffman RP. Detecting insulin resistance in polycystic ovary syndrome: purposes and pitfalls. Obstet Gynecol Surv 2004; 59:141-154.
    • (2004) Obstet Gynecol Surv , vol.59 , pp. 141-154
    • Legro, R.S.1    Castracane, V.D.2    Kauffman, R.P.3
  • 17
    • 33746220070 scopus 로고    scopus 로고
    • Molecular mechanisms of insulin resistance in polycystic ovary syndrome
    • Diamanti-Kandarakis E, Papavassiliou AG. Molecular mechanisms of insulin resistance in polycystic ovary syndrome. Trends Mol Med 2006; 12:324-332.
    • (2006) Trends Mol Med , vol.12 , pp. 324-332
    • Diamanti-Kandarakis, E.1    Papavassiliou, A.G.2
  • 18
    • 84860725114 scopus 로고    scopus 로고
    • Hyperinsulinemia amplifies GnRH agonist stimulated ovarian steroid secretion in women with polycystic ovary syndrome
    • Tosi F, Negri C, Perrone F, et al. Hyperinsulinemia amplifies GnRH agonist stimulated ovarian steroid secretion in women with polycystic ovary syndrome. J Clin Endocrinol Metab 2012; 97:1712-1719.
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 1712-1719
    • Tosi, F.1    Negri, C.2    Perrone, F.3
  • 19
    • 84869880616 scopus 로고    scopus 로고
    • Pharmacological treatment of obesity in patients with polycystic ovary syndrome
    • Kahal H, Atkin SL, Sathyapalan T. Pharmacological treatment of obesity in patients with polycystic ovary syndrome. J Obes 2011; 2011:402052.
    • (2011) J Obes , vol.2011 , pp. 402052
    • Kahal, H.1    Atkin, S.L.2    Sathyapalan, T.3
  • 20
  • 21
    • 27744585694 scopus 로고    scopus 로고
    • Genetics of polycystic ovary syndrome: Searching for the way out of the labyrinth
    • Diamanti-Kandarakis E, Piperi C. Genetics of polycystic ovary syndrome: searching for the way out of the labyrinth. Hum Reprod Update 2005; 11:631-643.
    • (2005) Hum Reprod Update , vol.11 , pp. 631-643
    • Diamanti-Kandarakis, E.1    Piperi, C.2
  • 22
    • 33846463033 scopus 로고    scopus 로고
    • The genetics of the polycystic ovary syndrome
    • Urbanek M. The genetics of the polycystic ovary syndrome. Nat Clin Pract Endocrinol Metab 2007; 3:103-111.
    • (2007) Nat Clin Pract Endocrinol Metab , vol.3 , pp. 103-111
    • Urbanek, M.1
  • 23
    • 84860719646 scopus 로고    scopus 로고
    • Abnormal expression of genes involved in inflammation, lipid metabolism, and wnt signaling in the adipose tissue of polycystic ovary syndrome
    • Chazenbalk G, Chen YH, Heneidi S, et al. Abnormal expression of genes involved in inflammation, lipid metabolism, and wnt signaling in the adipose tissue of polycystic ovary syndrome. J Clin Endocrinol Metab 2012; 97:E765-E770.
    • (2012) J Clin Endocrinol Metab , vol.97
    • Chazenbalk, G.1    Chen, Y.H.2    Heneidi, S.3
  • 24
    • 78651256136 scopus 로고    scopus 로고
    • Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3 2p21 and 9q33
    • Chen ZJ, Zhao H, He L, et al. Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33. 3 Nat Genet 2011; 43:55-59.
    • (2011) 3 Nat Genet , vol.43 , pp. 55-59
    • Chen, Z.J.1    Zhao, H.2    He, L.3
  • 25
    • 84862828534 scopus 로고    scopus 로고
    • Replication of association of DENND1A and THADA variants with polycystic ovary syndrome in European cohorts
    • Goodarzi MO, Jones MR, Li X, et al. Replication of association of DENND1A and THADA variants with polycystic ovary syndrome in European cohorts. J Med Genet 2012; 49:90-95.
    • (2012) J Med Genet , vol.49 , pp. 90-95
    • Goodarzi, M.O.1    Jones, M.R.2    Li, X.3
  • 26
    • 84863593326 scopus 로고    scopus 로고
    • Variants in DENND1A are associated with polycystic ovary syndrome in women of European ancestry
    • Welt CK, Styrkarsdottir U, Ehrmann DA, et al. Variants in DENND1A are associated with polycystic ovary syndrome in women of European ancestry. J Clin Endocrinol Metab 2012; 97:E1342-E1347.
    • (2012) J Clin Endocrinol Metab , vol.97
    • Welt, C.K.1    Styrkarsdottir, U.2    Ehrmann, D.A.3
  • 27
    • 80054851736 scopus 로고    scopus 로고
    • Susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21, and 9q333 in a cohort of Caucasian women
    • Lerchbaum E, Trummer O, Giuliani A, et al. Susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21, and 9q333 in a cohort of Caucasian women. Horm Metab Res 2011; 43:743-747.
    • (2011) Horm Metab Res , vol.43 , pp. 743-747
    • Lerchbaum, E.1    Trummer, O.2    Giuliani, A.3
  • 28
    • 80455156236 scopus 로고    scopus 로고
    • Epigenetic mechanism underlying the development of polycystic ovary syndrome (PCOS)-like phenotypes in prenatally androgenized rhesus monkeys
    • Xu N, Kwon S, Abbott DH, et al. Epigenetic mechanism underlying the development of polycystic ovary syndrome (PCOS)-like phenotypes in prenatally androgenized rhesus monkeys. PLoS One 2011; 6:e27286.
    • (2011) PLoS One , vol.6
    • Xu, N.1    Kwon, S.2    Abbott, D.H.3
  • 29
    • 33646403182 scopus 로고    scopus 로고
    • Review: Fetal programming of polycystic ovary syndrome by androgen excess: Evidence from experimental, clinical, and genetic association studies
    • Xita N, Tsatsoulis A. Review: fetal programming of polycystic ovary syndrome by androgen excess: evidence from experimental, clinical, and genetic association studies. J Clin Endocrinol Metab 2006; 91:1660-1666.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1660-1666
    • Xita, N.1    Tsatsoulis, A.2
  • 30
    • 77953709665 scopus 로고    scopus 로고
    • Epigenetics in polycystic ovary syndrome: A pilot study of global DNA methylation
    • e1
    • Xu N, Azziz R, Goodarzi MO. Epigenetics in polycystic ovary syndrome: a pilot study of global DNA methylation. Fertil Steril 2010; 94:781-783; e1.
    • (2010) Fertil Steril , vol.94 , pp. 781-783
    • Xu, N.1    Azziz, R.2    Goodarzi, M.O.3
  • 31
    • 0039568973 scopus 로고    scopus 로고
    • Major cardiovascular disease (CVD) during 1997-1999 and major CVD hospital discharge rates in 1997 among women with diabetes-United States
    • Centers for Disease Control and Prevention
    • Centers for Disease Control and Prevention. Major cardiovascular disease (CVD) during 1997-1999 and major CVD hospital discharge rates in 1997 among women with diabetes-United States. MMWR Morb Mortal Wkly Rep 2001; 50:948-954.
    • (2001) MMWR Morb Mortal Wkly Rep , vol.50 , pp. 948-954
  • 33
    • 79951948205 scopus 로고    scopus 로고
    • Lipid levels in polycystic ovary syndrome: Systematic review and meta-analysis
    • Wild RA, Rizzo M, Clifton S, et al. Lipid levels in polycystic ovary syndrome: systematic review and meta-analysis. Fertil Steril 2011; 95:1073-1079.
    • (2011) Fertil Steril , vol.95 , pp. 1073-1079
    • Wild, R.A.1    Rizzo, M.2    Clifton, S.3
  • 34
    • 50549087657 scopus 로고    scopus 로고
    • Cardiometabolic abnormalities in the polycystic ovary syndrome: Pharmacotherapeutic insights
    • Westerveld HE, Hoogendoorn M, de Jong AW, et al. Cardiometabolic abnormalities in the polycystic ovary syndrome: pharmacotherapeutic insights. Pharmacol Ther 2008; 119:223-241.
    • (2008) Pharmacol Ther , vol.119 , pp. 223-241
    • Westerveld, H.E.1    Hoogendoorn, M.2    De Jong, A.W.3
  • 35
    • 84857062605 scopus 로고    scopus 로고
    • Dyslipidemia in PCOS
    • Wild RA. Dyslipidemia in PCOS. Steroids 2012; 77:295-299.
    • (2012) Steroids , vol.77 , pp. 295-299
    • Wild, R.A.1
  • 36
    • 77956553268 scopus 로고    scopus 로고
    • Atherogenic metabolic profile in PCOS patients: Role of obesity and hyperandrogenism
    • Castelo-Branco C, Steinvarcel F, Osorio A, et al. Atherogenic metabolic profile in PCOS patients: role of obesity and hyperandrogenism. Gynecol Endocrinol 2010; 26:736-742.
    • (2010) Gynecol Endocrinol , vol.26 , pp. 736-742
    • Castelo-Branco, C.1    Steinvarcel, F.2    Osorio, A.3
  • 37
    • 33847004030 scopus 로고    scopus 로고
    • Effects of simvastatin and oral contraceptive agent on polycystic ovary syndrome: Prospective, randomized, crossover trial
    • Banaszewska B, Pawelczyk L, Spaczynski RZ, et al. Effects of simvastatin and oral contraceptive agent on polycystic ovary syndrome: prospective, randomized, crossover trial. J Clin Endocrinol Metab 2007; 92:456-461.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 456-461
    • Banaszewska, B.1    Pawelczyk, L.2    Spaczynski, R.Z.3
  • 38
    • 77958522601 scopus 로고    scopus 로고
    • Effects of metformin plus simvastatin on polycystic ovary syndrome: A prospective, randomized, doubleblind, placebo-controlled study
    • Kazerooni T, Shojaei-Baghini A, Dehbashi S, et al. Effects of metformin plus simvastatin on polycystic ovary syndrome: a prospective, randomized, doubleblind, placebo-controlled study. Fertil Steril 2010; 94:2208-2213.
    • (2010) Fertil Steril , vol.94 , pp. 2208-2213
    • Kazerooni, T.1    Shojaei-Baghini, A.2    Dehbashi, S.3
  • 39
    • 80155160476 scopus 로고    scopus 로고
    • Statins for women with polycystic ovary syndrome not actively trying to conceive
    • Raval AD, Hunter T, Stuckey B, et al. Statins for women with polycystic ovary syndrome not actively trying to conceive. Cochrane Database Syst Rev 2011:CD008565.
    • (2011) Cochrane Database Syst Rev
    • Raval, A.D.1    Hunter, T.2    Stuckey, B.3
  • 40
    • 84856426277 scopus 로고    scopus 로고
    • Simvastatin effects on androgens, inflammatory mediators, and endogenous pituitary gonadotropins among patients with PCOS undergoing IVF: Results from a prospective, randomized, placebo-controlled clinical trial
    • Rashidi B, Abediasl J, Tehraninejad E, et al. Simvastatin effects on androgens, inflammatory mediators, and endogenous pituitary gonadotropins among patients with PCOS undergoing IVF: results from a prospective, randomized, placebo-controlled clinical trial. J Investig Med 2011; 59: 912-916.
    • (2011) J Investig Med , vol.59 , pp. 912-916
    • Rashidi, B.1    Abediasl, J.2    Tehraninejad, E.3
  • 41
    • 37349006884 scopus 로고    scopus 로고
    • How should we manage atherogenic dyslipidemia in women with polycystic ovary syndrome?
    • Rizzo M, Berneis K, Carmina E, et al. How should we manage atherogenic dyslipidemia in women with polycystic ovary syndrome? Am J Obstet Gynecol 2008; 198:28.
    • (2008) Am J Obstet Gynecol , vol.198 , pp. 28
    • Rizzo, M.1    Berneis, K.2    Carmina, E.3
  • 42
    • 2942666200 scopus 로고    scopus 로고
    • Insulin sensitivity in women with polycystic ovary syndrome
    • Vrbikova J, Cibula D, Dvoráková K, et al. Insulin sensitivity in women with polycystic ovary syndrome. J Clin Endocrinol Metab 2004; 89:2942-2945.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 2942-2945
    • Vrbikova, J.1    Cibula, D.2    Dvoráková, K.3
  • 43
    • 33745213195 scopus 로고    scopus 로고
    • Insulin resistance in women with polycystic ovary syndrome
    • Dunaif A. Insulin resistance in women with polycystic ovary syndrome. Fertil Steril 2006; 86 (Suppl 1):S13-S14.
    • (2006) Fertil Steril , vol.86 , Issue.SUPPL. 1
    • Dunaif, A.1
  • 44
    • 84856768737 scopus 로고    scopus 로고
    • Insulin resistance is a sufficient basis for hyperandrogenism in lipodystrophic women with polycystic ovarian syndrome
    • Lungu AO, Zadeh ES, Goodling A, et al. Insulin resistance is a sufficient basis for hyperandrogenism in lipodystrophic women with polycystic ovarian syndrome. J Clin Endocrinol Metab 2012; 97:563-567.
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 563-567
    • Lungu, A.O.1    Zadeh, E.S.2    Goodling, A.3
  • 45
    • 30344448576 scopus 로고    scopus 로고
    • Prevalence and predictors of the metabolic syndrome in women with polycystic ovary syndrome
    • Ehrmann DA, Liljenquist DR, Kasza K, et al. Prevalence and predictors of the metabolic syndrome in women with polycystic ovary syndrome. J Clin Endocrinol Metab 2006; 91:48-53.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 48-53
    • Ehrmann, D.A.1    Liljenquist, D.R.2    Kasza, K.3
  • 46
    • 17844367331 scopus 로고    scopus 로고
    • Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome
    • Apridonidze T, Essah PA, Iuorno MJ, et al. Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome. J Clin Endocrinol Metab 2005; 90:1929-1935.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1929-1935
    • Apridonidze, T.1    Essah, P.A.2    Iuorno, M.J.3
  • 47
    • 32544457993 scopus 로고    scopus 로고
    • Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistance
    • Coviello AD, Legro RS, Dunaif A. Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistance. J Clin Endocrinol Metab 2006; 91:492-497.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 492-497
    • Coviello, A.D.1    Legro, R.S.2    Dunaif, A.3
  • 48
    • 80053305605 scopus 로고    scopus 로고
    • Comparison of diabetes mellitus and insulin resistance screening methods for women with polycystic ovary syndrome
    • Hurd WW, Abdel-Rahman MY, Ismail SA, et al. Comparison of diabetes mellitus and insulin resistance screening methods for women with polycystic ovary syndrome. Fertil Steril 2011; 96:1043-1047.
    • (2011) Fertil Steril , vol.96 , pp. 1043-1047
    • Hurd, W.W.1    Abdel-Rahman, M.Y.2    Ismail, S.A.3
  • 49
    • 78449260519 scopus 로고    scopus 로고
    • Insulin-sensitizing agents in the treatment of polycystic ovary syndrome: An update
    • Katsiki N, Hatzitolios AI. Insulin-sensitizing agents in the treatment of polycystic ovary syndrome: an update. Curr Opin Obstet Gynecol 2010; 22:466-476.
    • (2010) Curr Opin Obstet Gynecol , vol.22 , pp. 466-476
    • Katsiki, N.1    Hatzitolios, A.I.2
  • 50
    • 84864301691 scopus 로고    scopus 로고
    • Effect of metformin and pioglitazone treatment on cardiovascular risk profile in polycystic ovary syndrome
    • Ziaee A, Oveisi S, Abedini A, et al. Effect of metformin and pioglitazone treatment on cardiovascular risk profile in polycystic ovary syndrome. Acta Med Indones 2012; 44:16-22.
    • (2012) Acta Med Indones , vol.44 , pp. 16-22
    • Ziaee, A.1    Oveisi, S.2    Abedini, A.3
  • 51
    • 79955596156 scopus 로고    scopus 로고
    • Effect of dose escalation of metformin on clinical features, insulin sensitivity and androgen profile in polycystic ovary syndrome
    • Yasmin E, Glanville J, Barth J, et al. Effect of dose escalation of metformin on clinical features, insulin sensitivity and androgen profile in polycystic ovary syndrome. Eur J Obstet Gynecol Reprod Biol 2011; 156:67-71.
    • (2011) Eur J Obstet Gynecol Reprod Biol , vol.156 , pp. 67-71
    • Yasmin, E.1    Glanville, J.2    Barth, J.3
  • 52
    • 79952544573 scopus 로고    scopus 로고
    • Metformin versus metformin plus rosiglitazone in women with polycystic ovary syndrome
    • Liao L, Tian YJ, Zhao JJ, et al. Metformin versus metformin plus rosiglitazone in women with polycystic ovary syndrome. Chin Med J (Engl) 2011; 124:714-718.
    • (2011) Chin Med J (Engl , vol.124 , pp. 714-718
    • Liao, L.1    Tian, Y.J.2    Zhao, J.J.3
  • 53
    • 78650420485 scopus 로고    scopus 로고
    • Effect of the insulin sensitizers metformin and pioglitazone on endothelial function in young women with polycystic ovary syndrome: A prospective randomized study
    • Naka KK, Kalantaridou SN, Kravariti M, et al. Effect of the insulin sensitizers metformin and pioglitazone on endothelial function in young women with polycystic ovary syndrome: a prospective randomized study. Fertil Steril 2011; 95:203-209.
    • (2011) Fertil Steril , vol.95 , pp. 203-209
    • Naka, K.K.1    Kalantaridou, S.N.2    Kravariti, M.3
  • 54
    • 84860761407 scopus 로고    scopus 로고
    • Metformin improves pregnancy and live-birth rates in women with polycystic ovary syndrome (PCOS): A multicenter, double-blind, placebo-controlled randomized trial
    • Morin-Papunen L, Rantala AS, Unkila-Kallio L, et al. Metformin improves pregnancy and live-birth rates in women with polycystic ovary syndrome (PCOS): a multicenter, double-blind, placebo-controlled randomized trial. J Clin Endocrinol Metab 2012; 97:1492-1500.
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 1492-1500
    • Morin-Papunen, L.1    Rantala, A.S.2    Unkila-Kallio, L.3
  • 55
    • 79958813551 scopus 로고    scopus 로고
    • The administration of metformin during pregnancy reduces polycystic ovary syndrome related gestational complications
    • De Leo V, Musacchio MC, Piomboni P, et al. The administration of metformin during pregnancy reduces polycystic ovary syndrome related gestational complications. Eur J Obstet Gynecol Reprod Biol 2011; 157:63-66.
    • (2011) Eur J Obstet Gynecol Reprod Biol , vol.157 , pp. 63-66
    • De Leo, V.1    Musacchio, M.C.2    Piomboni, P.3
  • 56
    • 84862097793 scopus 로고    scopus 로고
    • Pregnancy outcomes and the effect of metformin treatment in women with polycystic ovary syndrome: An overview
    • Ghazeeri GS, Nassar AH, Younes Z, et al. Pregnancy outcomes and the effect of metformin treatment in women with polycystic ovary syndrome: an overview. Acta Obstet Gynecol Scand 2012; 91:658-678.
    • (2012) Acta Obstet Gynecol Scand , vol.91 , pp. 658-678
    • Ghazeeri, G.S.1    Nassar, A.H.2    Younes, Z.3
  • 57
    • 33846909985 scopus 로고    scopus 로고
    • Quality of life and psychological morbidity in women with polycystic ovary syndrome: Body mass index, age and the provision of patient information are significant modifiers
    • Ching HL, Burke V, Stuckey BG. Quality of life and psychological morbidity in women with polycystic ovary syndrome: body mass index, age and the provision of patient information are significant modifiers. Clin Endocrinol (Oxf) 2007; 66:373-379.
    • (2007) Clin Endocrinol (Oxf , vol.66 , pp. 373-379
    • Ching, H.L.1    Burke, V.2    Stuckey, B.G.3
  • 58
    • 26444434868 scopus 로고    scopus 로고
    • Obesity and extreme obesity, manifest by ages 20-24 years, continuing through 32-41 years in women, should alert physicians to the diagnostic likelihood of polycystic ovary syndrome as a reversible underlying endocrinopathy
    • Glueck CJ, Dharashivkar S, Wang P, et al. Obesity and extreme obesity, manifest by ages 20-24 years, continuing through 32-41 years in women, should alert physicians to the diagnostic likelihood of polycystic ovary syndrome as a reversible underlying endocrinopathy. Eur J Obstet Gynecol Reprod Biol 2005; 122:206-212.
    • (2005) Eur J Obstet Gynecol Reprod Biol , vol.122 , pp. 206-212
    • Glueck, C.J.1    Dharashivkar, S.2    Wang, P.3
  • 59
    • 84856102468 scopus 로고    scopus 로고
    • Evaluation of body fat distribution in PCOS and its association with carotid atherosclerosis and insulin resistance
    • Karabulut A, YaylaliGF, Demirlenk S, et al. Evaluation of body fat distribution in PCOS and its association with carotid atherosclerosis and insulin resistance. Gynecol Endocrinol 2012; 28:111-114.
    • (2012) Gynecol Endocrinol , vol.28 , pp. 111-114
    • Karabulut, A.1    Yaylali, G.F.2    Demirlenk, S.3
  • 60
    • 80655148241 scopus 로고    scopus 로고
    • Effect of lifestyle intervention on features of polycystic ovarian syndrome, metabolic syndrome, and intima-media thickness in obese adolescent girls
    • Lass N, Kleber M, Winkel K, et al. Effect of lifestyle intervention on features of polycystic ovarian syndrome, metabolic syndrome, and intima-media thickness in obese adolescent girls. J Clin Endocrinol Metab 2011; 96:3533-3540.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 3533-3540
    • Lass, N.1    Kleber, M.2    Winkel, K.3
  • 61
    • 1642313670 scopus 로고    scopus 로고
    • A randomized trial of the effects of two types of short-term hypocaloric diets on weight loss in women with polycystic ovary syndrome
    • Stamets K, Taylor DS, Kunselman A, et al. A randomized trial of the effects of two types of short-term hypocaloric diets on weight loss in women with polycystic ovary syndrome. Fertil Steril 2004; 81:630-637.
    • (2004) Fertil Steril , vol.81 , pp. 630-637
    • Stamets, K.1    Taylor, D.S.2    Kunselman, A.3
  • 62
    • 70749121763 scopus 로고    scopus 로고
    • Treatment of obesity in polycystic ovary syndrome: A position statement of the Androgen Excess and Polycystic Ovary Syndrome Society
    • Moran LJ, Pasquali R, Teede HJ, et al. Treatment of obesity in polycystic ovary syndrome: a position statement of the Androgen Excess and Polycystic Ovary Syndrome Society. Fertil Steril 2009; 92:1966-1982.
    • (2009) Fertil Steril , vol.92 , pp. 1966-1982
    • Moran, L.J.1    Pasquali, R.2    Teede, H.J.3
  • 63
    • 79951755056 scopus 로고    scopus 로고
    • Exercise therapy in polycystic ovary syndrome: A systematic review
    • Harrison CL, Lombard CB, Moran LJ, et al. Exercise therapy in polycystic ovary syndrome: a systematic review. Hum Reprod Update 2011; 17:171-183.
    • (2011) Hum Reprod Update , vol.17 , pp. 171-183
    • Harrison, C.L.1    Lombard, C.B.2    Moran, L.J.3
  • 64
    • 28744439379 scopus 로고    scopus 로고
    • The polycystic ovary syndrome associated with morbid obesity may resolve after weight loss induced by bariatric surgery
    • Escobar-Morreale HF, Botella-Carretero JI, Alvarez-Blasco F, et al. The polycystic ovary syndrome associated with morbid obesity may resolve after weight loss induced by bariatric surgery. J Clin Endocrinol Metab 2005; 90:6364-6369.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 6364-6369
    • Escobar-Morreale, H.F.1    Botella-Carretero, J.I.2    Alvarez-Blasco, F.3
  • 65
    • 39849099669 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and the metabolic syndrome: An update
    • Rector RS, Thyfault JP, Wei Y, et al. Nonalcoholic fatty liver disease and the metabolic syndrome: an update. World J Gastroenterol 2008; 14:185-192.
    • (2008) World J Gastroenterol , vol.14 , pp. 185-192
    • Rector, R.S.1    Thyfault, J.P.2    Wei, Y.3
  • 66
    • 33646401803 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis and nonalcoholic fatty liver disease in young women with polycystic ovary syndrome
    • Setji TL, Holland ND, Sanders LL, et al. Nonalcoholic steatohepatitis and nonalcoholic fatty liver disease in young women with polycystic ovary syndrome. J Clin Endocrinol Metab 2006; 91:1741-1747.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1741-1747
    • Setji, T.L.1    Holland, N.D.2    Sanders, L.L.3
  • 67
    • 70349256202 scopus 로고    scopus 로고
    • In overweight/obese but not in normal-weight women, polycystic ovary syndrome is associated with elevated liver enzymes compared to controls
    • Economou F, Xyrafis X, Livadas S, et al. In overweight/obese but not in normal-weight women, polycystic ovary syndrome is associated with elevated liver enzymes compared to controls. Hormones (Athens) 2009; 8:199-206.
    • (2009) Hormones (Athens , vol.8 , pp. 199-206
    • Economou, F.1    Xyrafis, X.2    Livadas, S.3
  • 68
    • 72849152902 scopus 로고    scopus 로고
    • Increased androgen bioavailability is associated with nonalcoholic fatty liver disease in women with polycystic ovary syndrome
    • Vassilatou E, Lafoyianni S, Vryonidou A, et al. Increased androgen bioavailability is associated with nonalcoholic fatty liver disease in women with polycystic ovary syndrome. Hum Reprod 2010; 25:212-220.
    • (2010) Hum Reprod , vol.25 , pp. 212-220
    • Vassilatou, E.1    Lafoyianni, S.2    Vryonidou, A.3
  • 69
    • 79952330782 scopus 로고    scopus 로고
    • Prevalence of non alcoholic fatty liver disease in premenopausal, posmenopausal and polycystic ovary syndrome women. The role of estrogens
    • Gutierrez-Grobe Y, et al. Prevalence of non alcoholic fatty liver disease in premenopausal, posmenopausal and polycystic ovary syndrome women. The role of estrogens. Ann Hepatol 2010; 9:402-409.
    • (2010) Ann Hepatol , vol.9 , pp. 402-409
    • Gutierrez-Grobe, Y.1
  • 70
    • 84861591910 scopus 로고    scopus 로고
    • The Diagnosis and management of nonalcoholic fatty liver disease: Practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology
    • Chalasani N, Younossi Z, Lavine JE, et al. The Diagnosis and management of nonalcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology. Gastroenterology 2012; 142:1592-1609.
    • (2012) Gastroenterology , vol.142 , pp. 1592-1609
    • Chalasani, N.1    Younossi, Z.2    Lavine, J.E.3
  • 71
    • 77952126834 scopus 로고    scopus 로고
    • Current evidence of acupuncture on polycystic ovarian syndrome
    • Lim CE, Wong WS. Current evidence of acupuncture on polycystic ovarian syndrome. Gynecol Endocrinol 2010; 26:473-478.
    • (2010) Gynecol Endocrinol , vol.26 , pp. 473-478
    • Lim, C.E.1    Wong, W.S.2
  • 72
    • 79959583032 scopus 로고    scopus 로고
    • The physiological basis of complementary and alternative medicines for polycystic ovary syndrome
    • Raja-Khan N, Stener-Victorin E, Wu X, et al. The physiological basis of complementary and alternative medicines for polycystic ovary syndrome. Am J Physiol Endocrinol Metab 2011; 301:E1-E10.
    • (2011) Am J Physiol Endocrinol Metab , vol.301
    • Raja-Khan, N.1    Stener-Victorin, E.2    Wu, X.3
  • 73
    • 80054684057 scopus 로고    scopus 로고
    • Meta-analysis of cardiovascular disease risk markers in women with polycystic ovary syndrome
    • Toulis KA, Goulis DG, Mintziori G, et al. Meta-analysis of cardiovascular disease risk markers in women with polycystic ovary syndrome. Hum Reprod Update 2011; 17:741-760.
    • (2011) Hum Reprod Update , vol.17 , pp. 741-760
    • Toulis, K.A.1    Goulis, D.G.2    Mintziori, G.3
  • 74
    • 33644558330 scopus 로고    scopus 로고
    • Cardiovascular disease in the polycystic ovary syndrome: New insights and perspectives
    • Cussons AJ, Stuckey BG, Watts GF. Cardiovascular disease in the polycystic ovary syndrome: new insights and perspectives. Atherosclerosis 2006; 185:227-239.
    • (2006) Atherosclerosis , vol.185 , pp. 227-239
    • Cussons, A.J.1    Stuckey, B.G.2    Watts, G.F.3
  • 75
    • 83155165470 scopus 로고    scopus 로고
    • Cardiovascular disease and risk factors in PCOS women of postmenopausal age: A 21-year controlled follow-up study
    • Schmidt J, Landin-Wilhelmsen K, Brä nnström M, et al. Cardiovascular disease and risk factors in PCOS women of postmenopausal age: a 21-year controlled follow-up study. J Clin Endocrinol Metab 2011; 96:3794-3803.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 3794-3803
    • Schmidt, J.1    Landin-Wilhelmsen, K.2    Brännström, M.3
  • 76
    • 0038307320 scopus 로고    scopus 로고
    • Polycystic ovary syndrome and cardiovascular disease: A premature association?
    • Legro RS. Polycystic ovary syndrome and cardiovascular disease: a premature association? Endocr Rev 2003; 24:302-312.
    • (2003) Endocr Rev , vol.24 , pp. 302-312
    • Legro, R.S.1


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