Regulation of autophagy in cardiomyocytes by Ins(1,4,5)P3 and IP3-receptors

Journal of Molecular and Cellular Cardiology

Volumn 54, Issue 1, 2013, Pages 19-24

  Wong, Albert ^a,b   Grubb, David R ^a   Cooley, Nicola ^a   Luo, Jieting ^a   Woodcock, Elizabeth A ^a,b  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

Autophagosome; Beclin 1; FoxO1; Ins(1,4,5)P3; IP3 5 phosphatase; IP3 R

Indexed keywords

BECLIN 1; INOSITOL 1,4,5 TRISPHOSPHATE; INOSITOL 1,4,5 TRISPHOSPHATE 5 PHOSPHATASE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; MICROTUBULE LIGHT CHAIN 3; MICROTUBULE PROTEIN; PROTEIN P62; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOPHAGY; CARBOHYDRATE METABOLISM; CONTROLLED STUDY; DISEASE COURSE; HEART FAILURE; HEART MUSCLE CELL; INTRACELLULAR SIGNALING; LIGAND BINDING; MOLECULAR PATHOLOGY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BINDING SITES; BORON COMPOUNDS; CELLS, CULTURED; CYTOPLASMIC GRANULES; FORKHEAD TRANSCRIPTION FACTORS; HEART VENTRICLES; HEAT-SHOCK PROTEINS; INOSITOL 1,4,5-TRISPHOSPHATE; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; LYSOSOMES; MICROTUBULE-ASSOCIATED PROTEINS; MYOCYTES, CARDIAC; NERVE TISSUE PROTEINS; PHAGOSOMES; PHOSPHATIDYLETHANOLAMINES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

RATTUS;

EID: 84869876713     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2012.10.014     Document Type: Article

References (47)

1. Marks A.R. Cardiac intracellular calcium release channels: role in heart failure. Circ Res 2000, 87:8-11.
2. Yamda J., Ohkusa T., Nao T., Ueyama T., Yano M., Kobayashi S., et al. Up-regulation of inositol 1,4,5 trisphosphate receptor expression in atrial tissue in patients with chronic atrial fibrillation. J Am Coll Cardiol 2001, 37:1111-1119.
3. Liang X., Xie H., Zhu P.H., Hu J., Zhao Q., Wang C.S., et al. Enhanced activity of inositol-1,4,5-trisphosphate receptors in atrial myocytes of atrial fibrillation patients. Cardiology 2009, 114:180-191.
4. 2+ release channels in rat cardiac hypertrophy induced by aortic stenosis. Circulation 1998, 98:2477-2486.
5. 3)-receptor type 2-deficient mice. Circ Res 2005, 96:1274-1281.
6. 3 receptor regulates cardiac hypertrophy in response to select stimuli. Circ Res 2010, 107:656-666.
7. Gottlieb R.A., Mentzer R.M. Autophagy during cardiac stress: joys and frustrations of autophagy. Annu Rev Physiol 2010, 72:45-59.
8. Gottlieb R.A., Finley K.D., Mentzer R.M. Cardioprotection requires taking out the trash. Basic Res Cardiol 2009, 104:169-180.
9. Sengupta A., Molkentin J.D., Yutzey K.E. FoxO transcription factors promote autophagy in cardiomyocytes. J Biol Chem 2009, 284:28319-28331.
10. Matsui Y., Takagi H., Qu X.P., Abdellatif M., Sakoda H., Asano T., et al. Distinct roles of autophagy in the heart during ischemia and reperfusion - roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Circ Res 2007, 100:914-922.
11. Chang N.C., Nguyen M., Germain M., Shore G.C. Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1. EMBO J 2010, 29:606-618.
12. Luo S., Rubinsztein D.C. Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL. Cell Death Differ 2010, 17:268-277.
13. Vicencio J.M., Ortiz C., Criollo A., Jones A.W., Kepp O., Galluzzi L., et al. The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1. Cell Death Differ 2009, 16:1006-1017.
14. 2+ transfer to mitochondria. Cell 2010, 142:270-283.
15. Williams A., Sarkar S., Cuddon P., Ttofi E.K., Saiki S., Siddiqi F.H., et al. Novel targets for Huntington's disease in an mTOR-independent autophagy pathway. Nat Chem Biol 2008, 4:295-305.
16. 3 levels regulate autophagy: biology and therapeutic speculations. Autophagy 2006, 2:132-134.
17. 2+ leak in intact ventricular myocytes from rabbits in heart failure. Circ Res 2003, 93:592-594.
18. Nemchenko A., Chiong M., Turer A., Lavandero S., Hill J.A. Autophagy as a therapeutic target in cardiovascular disease. J Mol Cell Cardiol 2011, 51:584-593.
19. 1-adrenergic receptor signaling in cardiomyocytes - dissociation of Ras and Rho pathways. J Biol Chem 1996, 271:31185-31190.
20. 3 regulates phospholipase Cβ1 expression in cardiomyocytes. J Mol Cell Cardiol 2008, 45:679-684.
21. 3R channels. Proc Natl Acad Sci U S A 2005, 102:7859-7864.
22. 2+ homeostasis. J Biol Chem 2002, 277:48779-48785.
23. Klionsky D.J., Abeliovich H., Agostinis P., Agrawal D.K., Aliev G., Askew D.S., et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 2008, 4:151-175.
24. Sengupta A., Molkentin J.D., Paik J.H., DePinho R.A., Yutzey K.E. FoxO transcription factors promote cardiomyocyte survival upon induction of oxidative stress. J Biol Chem 2011, 286:7468-7478.
25. Bilmen J.G., Michelangeli F. Inhibition of the type 1 inositol 1,4,5-trisphosphate receptor by 2-aminoethoxydiphenylborate. Cell Signal 2002, 14:955-960.
26. Komatsu M., Kageyama S., Ichimura Y. p62/SQSTM1/A170: physiology and pathology. Pharmacol Res 2012, (Epub Date 2012/07/13).
27. Su H., Wang X. p62 stages an interplay between the ubiquitin-proteasome system and autophagy in the heart of defense against proteotoxic stress. Trends Cardiovasc Med 2011, 21:224-228.
28. Zheng Q., Su H., Ranek M.J., Wang X. Autophagy and p62 in cardiac proteinopathy. Circ Res 2011, 109:296-308.
29. Qipshidze N., Tyagi N., Metreveli N., Lominadze D., Tyagi S.C. Autophagy mechanism of right ventricular remodeling in murine model of pulmonary artery constriction. Am J Physiol Heart Circ Physiol 2012, 302:H688-H696.
30. Majerus P.W., Kisseleva M.V., Norris F.A. The role of phosphatases in inositol signaling reactions. J Biol Chem 1999, 274:10669-10672.
31. Mourey R.J., Estevez V.A., Marecek J.F., Barrow R.K., Prestwich G.D., Snyder S.H. Inositol 1,4,5-trisphosphate receptors - labeling the inositol 1,4,5-trisphosphate binding site with photoaffinity ligands. Biochemistry 1993, 32:1719-1726.
32. Khan M.T., Joseph S.K. Role of inositol trisphosphate receptors in autophagy in DT40 cells. J Biol Chem 2010, 285:16912-16920.
33. Whelan R.S., Kaplinskiy V., Kitsis R.N. Cell death in the pathogenesis of heart disease: mechanisms and significance. Annu Rev Physiol 2010, 72:19-44.
34. Pattingre S., Tassa A., Qu X., Garuti R., Liang X.H., Mizushima N., et al. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 2005, 122:927-939.
35. Maiuri M.C., Criollo A., Kroemer G. Crosstalk between apoptosis and autophagy within the Beclin 1 interactome. EMBO J 2010, 29:515-516.
36. Menniti F.S., Oliver K.G., Putney J.W., Shears S.B. Inositol phosphates and cell signaling - new views of InsP5 and InsP6. Trends Biochem Sci 1993, 18:53-56.
37. Stephens L.R., Hawkins P.T., Stanley A.F., Moore T., Poyner D.R., Morris P.J., et al. myo-Inositol pentakisphosphates. Structure biological occurrence and phosphorylation to myo-inositol hexakisphosphate. Biochem J 1991, 275:485-499.
38. Anekonda T.S., Wadsworth T.L., Sabin R., Frahler K., Harris C., Petriko B., et al. Phytic acid as a potential treatment for Alzheimer's pathology: evidence from animal and in vitro models. J Alzheimers Dis 2011, 23:21-35.
39. Nagata E., Saiardi A., Tsukamoto H., Satoh T., Itoh Y., Itoh J., et al. Inositol hexakisphosphate kinases promote autophagy. Int J Biochem Cell Biol 2011, 42:2065-2071.
40. Kockskamper J., Zima A.V., Roderick H.L., Pieske B., Blatter L.A., Bootman M.D. Emerging roles of inositol 1,4,5-trisphosphate signaling in cardiac myocytes. J Mol Cell Cardiol 2008, 45:128-147.
41. 3 receptors and inositol phosphates in the heart - evolutionary artefacts or active signal transducers?. Pharmacol Ther 2005, 107:240-251.
42. 2+ signaling in cardiac myocyte excitation-transcription coupling. J Clin Invest 2006, 116:675-682.
43. Anderson K., Dart A., Woodcock E. Inositol phosphate release and metabolism during myocardial ischemia and reperfusion in rat heart. Circ Res 1995, 76:261-268.
44. Woodcock E.A., Grubb D.R., Filtz T.M., Marasco S., Luo J.T., McLeod-Dryden T.J., et al. Selective activation of the "b" splice variant of phospholipase Cβ1 in chronically dilated human and mouse atria. J Mol Cell Cardiol 2009, 47:676-683.
45. Sciarretta S., Hariharan N., Monden Y., Zablocki D., Sadoshima J. Is autophagy in response to ischemia and reperfusion protective or detrimental for the heart?. Pediatr Cardiol 2011, 32:275-281.
46. Gustafsson A.B., Gottlieb R.A. Autophagy in ischemic heart disease. Circ Res 2009, 104:150-158.
47. Chen M.C., Chang J.P., Wang Y.H., Liu W.H., Ho W.C., Chang H.W. Autophagy as a mechanism for myolysis of cardiomyocytes in mitral regurgitation. Eur J Clin Invest 2011, 41:299-307.