Hyaluronic acid based scaffolds for tissue engineering - A review

Carbohydrate Polymers

Volumn 92, Issue 2, 2013, Pages 1262-1279

  Collins, Maurice N ^a   Birkinshaw, Colin ^a  

^a UNIVERSITY OF LIMERICK   (Ireland)

Author keywords

Hyaluronic acid; Scaffolds; Tissue engineering

Indexed keywords

BIOLOGICAL FUNCTIONS; CARBOHYDRATE POLYMERS; FORMATION MECHANISM; LATEST TECHNOLOGY; MODE OF ACTION; RECENT RESEARCHES; SCAFFOLDS FOR TISSUE ENGINEERING; SOLUTION PROPERTY; TISSUE ENGINEERING APPLICATIONS; TISSUE SCAFFOLDING;

CARBOHYDRATES; HYALURONIC ACID; ORGANIC ACIDS; SCAFFOLDS; TISSUE; TISSUE ENGINEERING;

SCAFFOLDS (BIOLOGY);

HYALURONIC ACID; TISSUE SCAFFOLD;

ANIMAL; CHEMISTRY; HUMAN; METABOLISM; METHODOLOGY; REVIEW; TISSUE ENGINEERING;

ANIMALS; HUMANS; HYALURONIC ACID; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84869876067     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2012.10.028     Document Type: Review

References (145)

1. G. Acunzo, M. Guida, M. Pellicano, G.A. Tommaselli, A. Di Spiezio Sardo, and G. Bifulco Effectiveness of autocrosslinked hyaluronic acid gel in the prevention of intrauterine adhesions after hysteroscopic adhesiolysis: a prospective, randomized, controlled study Human Reproduction 18 9 2003 1918 1921
2. S. Agarwal, J. Wendorff, and A. Greiner Progress in the field of electrospinning for tissue engineering applications Advanced Materials 21 2009 3343 3351
3. D.D. Allison, and K.J. Grande-Allen Review. Hyaluronan: a powerful tissue engineering tool Tissue Engineering 12 8 2006 2131 2140
4. B. Ananthanarayanan, Y. Kim, and S. Kumar Elucidating the mechanobiology of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform Biomaterials 32 31 2011 7913 7923
5. J.C. Antunes, J.M. Oliveira, R.L. Reis, J.M. Soria, J.L. Gómez-Ribelles, and J.F. Mano Novel poly(L-lactic acid)/hyaluronic acid macroporous hybrid scaffolds: characterization and assessment of cytotoxicity Journal of Biomedical Materials Research Part A 94A 3 2010 856 869
6. J.C. Antunes, J.M. Oliveira, R.L. Reis, J.M. Soria, J.L. Gómez-Ribelles, and J.F. Mano Novel poly(L-lactic acid)/hyaluronic acid macroporous hybrid scaffolds: characterization and assessment of cytotoxicity Journal of Biomedical Materials Research Part A 94A 3 2011 856 869
7. M. Arnal-Pastor, A. Valles-Lluch, M. Keicher, and M.M.n. Pradas Coating typologies and constrained swelling of hyaluronic acid gels within scaffold pores Journal of Colloid and Interface Science 361 1 2011 361 369
8. R. Baker Membrane technology and applications 2000 McGraw-Hill
9. Balazs, E. A., Leshchiner, A., Leshchiner, A., & Band, P. (1987). Chemically modified hyaluronic acid preparation and method of recovery thereof from animal tissues. United States Patent 4,713,448. US: Biomatrix, Inc. (Ridgefield, NJ).
10. A. Barbetta, A. Carrino, M. Costantini, and M. Dentini Polysaccharide based scaffolds obtained by freezing the external phase of gas-in-liquid foams Soft Matter 6 20 2010 5213 5224
11. A. Bent, J. Foote, S. Siegel, G. Faerber, R. Chao, and E. Gormley Collagen implant for treating stress urinary incontinence in women with urethral hypermobility Journal of Urology 166 2001 1354 1357
12. S. Bhattacharyya, S. Guillot, H. Dabboue, J.-F. Tranchant, and J.-P. Salvetat Carbon nanotubes as structural nanofibers for hyaluronic acid hydrogel scaffolds Biomacromolecules 9 2 2008 505 509
13. E.K. Brenner, J.D. Schiffman, E.A. Thompson, L.J. Toth, and C.L. Schauer Electrospinning of hyaluronic acid nanofibers from aqueous ammonium solutions Carbohydrate Polymers 87 1 2012 926 929
14. J.A. Burdick, and G.D. Prestwich Hyaluronic acid hydrogels for biomedical applications Advanced Materials 23 12 2011 H41 H56
15. Y.-Z. Cai, G.-R. Zhang, L.-L. Wang, Y.-Z. Jiang, H.-W. Ouyang, and X.-H. Zou Novel biodegradable three-dimensional macroporous scaffold using aligned electrospun nanofibrous yarns for bone tissue engineering Journal of Biomedical Materials Research Part A 100A 5 2012 1187 1194
16. C. Caravaggi, R. De Giglio, C. Pritelli, M. Sommaria, S. Dalla Noce, and E. Faglia HYAFF 11-based autologous dermal and epidermal grafts in the treatment of noninfected diabetic plantar and dorsal foot ulcers Diabetes Care 26 10 2003 2853 2859
17. S.J. Chang, Y.-T. Huang, S.-C. Yang, S.-M. Kuo, and M.-W. Lee In vitro properties of gellan gum sponge as the dental filling to maintain alveolar space Carbohydrate Polymers 88 2 2012 684 689
18. F. Chen, M. Tian, D. Zhang, J. Wang, Q. Wang, and X. Yu Preparation and characterization of oxidized alginate covalently cross-linked galactosylated chitosan scaffold for liver tissue engineering Materials Science and Engineering: C 32 2 2011 310 320
19. G.P. Chen, T. Ushida, and T. Tateishi Scaffold design for tissue engineering Macromolecular Bioscience 2 2 2002 67 77
20. J.D. Chen, Y. Wang, and X. Chen In situ fabrication of nano-hydroxyapatite in a macroporous chitosan scaffold for tissue engineering Journal of Biomaterials Science, Polymer Edition 20 11 2009 1555 1565
21. W. Chen, and G. Abatangelo Functions of hyaluronan in wound repair Wound Repair Regeneration 7 2 1999 79 89
22. C. Chiari, U. Koller, R. Dorotka, C. Eder, R. Plasenzotti, and S. Lang A tissue engineering approach to meniscus regeneration in a sheep model Osteoarthritis and Cartilage 14 10 2006 1056 1065
23. M. Collins, and C. Birkinshaw Physical properties of crosslinked hyaluronic acid hydrogels Journal of Materials Science: Materials in Medicine 19 11 2008 3335 3343
24. M.N. Collins Fabrication of porous re-sorbable scaffolds for tissue engineering Materials Science 2007 University of Limerick
25. M.N. Collins, and C. Birkinshaw Comparison of the effectiveness of four different crosslinking agents with hyaluronic acid hydrogel films for tissue-culture applications Journal of Applied Polymer Science 104 5 2007 3183 3191
26. M.N. Collins, and C. Birkinshaw Investigation of the swelling behavior of crosslinked hyaluronic acid films and hydrogels produced using homogeneous reactions Journal of Applied Polymer Science 109 2 2008 923 931
27. M.N. Collins, and C. Birkinshaw Morphology of crosslinked hyaluronic acid porous hydrogels Journal of Applied Polymer Science 120 2 2011 1040 1049
28. T. Dai, M. Tanaka, Y.-Y. Huang, and M.R. Hamblin Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects Expert Review of Anti-Infective Therapy 9 7 2011 857 879
29. N. Davidenko, J.J. Campbell, E.S. Thian, C.J. Watson, and R.E. Cameron Collagen-hyaluronic acid scaffolds for adipose tissue engineering Acta Biomaterialia 6 10 2010 3957 3968
30. F. Dehghani, and N. Annabi Engineering porous scaffolds using gas-based techniques Current Opinion in Biotechnology 22 5 2011 661 666
31. P.E. Dijkman, A. Driessen-Mol, L. Frese, S.P. Hoerstrup, and F.P.T. Baaijens Decellularized homologous tissue-engineered heart valves as off-the-shelf alternatives to xeno- and homografts Biomaterials 33 18 2012 4545 4554
32. C. Eenschooten, A. Vaccaro, F. Delie, F. Guillaumie, K. TÃ̧mmeraas, and G.M. Kontogeorgis Novel self-associative and multiphasic nanostructured soft carriers based on amphiphilic hyaluronic acid derivatives Carbohydrate Polymers 87 1 2012 444 451
33. P. Eiselt, K.Y. Lee, and D.J. Mooney Rigidity of two-component hydrogels prepared from alginate and poly(ethylene glycol)-diamines Macromolecules 32 1999 5561 5566
34. A.K. Ekaputra, G.D. Prestwich, S.M. Cool, and D.W. Hutmacher The three-dimensional vascularization of growth factor-releasing hybrid scaffold of poly (caprolactone)/collagen fibers and hyaluronic acid hydrogel Biomaterials 32 32 2011 8108 8117
35. I.E. Erickson, S.R. Kestle, K.H. Zellars, M.J. Farrell, M. Kim, and J.A. Burdick High mesenchymal stem cell seeding densities in hyaluronic acid hydrogels produce engineered cartilage with native tissue properties Acta Biomaterialia 8 8 2012 3027 3034
36. L. Espandar, B. Bunnell, G.Y. Wang, P. Gregory, C. McBride, and M. Moshirfar Adipose-derived stem cells on hyaluronic acid derived scaffold: a new horizon in bioengineered cornea Archives of Ophthalmology 130 2 2012 202 208
37. Faga, A., Nicoletti, G., Brenta, F., Scevola, S., Abatangelo, G., & Brun, P. Hyaluronic acid three-dimensional scaffold for surgical revision of retracting scars: a human experimental study. International Wound Journal, http://dx.doi.org/10.1111/j.1742-481X.2012.00981.x, in press.
38. S. Fagien, and D. Cassuto Reconstituted injectable hyaluronic acid: expanded applications in facial aesthetics and additional thoughts on the mechanism of action in cosmetic medicine Plastic and Reconstructive Surgery 130 1 2012 208 217 210.1097/PRS.1090b1013e318254b318253f318256
39. M. Flaibani, and N. Elvassore Gas anti-solvent precipitation assisted salt leaching for generation of micro- and nano-porous wall in bio-polymeric 3D scaffolds Materials Science and Engineering 32 6 2012 1632 1639
40. U. Freymann, M. Endres, K. Neumann, H.J. Scholman, L. Morawietz, and C. Kaps Expanded human meniscus-derived cells in 3-D polymer hyaluronan scaffolds for meniscus repair Acta Biomaterialia 8 2 2011 677 685
41. G. Galassi, P. Brun, M. Radice, R. Cortivo, G.F. Zanon, and P. Genovese In vitro reconstructed dermis implanyed in human wounds: degradation studies of the HA-based supporting scaffold Biomaterials 21 2000 2183 2191
42. M. Guida, G. Acunzo, A. Di Spiezio Sardo, G. Bifulco, R. Piccoli, and M. Pellicano Effectiveness of autocrosslinked hyaluronic acid gel in the prevention of intrauterine adhesions after hysteroscopic surgery: a prospective, randomized, controlled study Human Reproduction 19 6 2004 1461 1464
43. L.A. Gurski, A.K. Jha, C. Zhang, X. Jia, and M.C. Farach-Carson Hyaluronic acid-based hydrogels as 3D matrices for in vitro evaluation of chemotherapeutic drugs using poorly adherent prostate cancer cells Biomaterials 30 30 2009 6076 6085
44. D.W. Hutmacher Scaffolds in tissue engineering bone and cartilage Biomaterials 21 24 2000 2529 2543
45. S. Ibrahim, B. Joddar, M. Craps, and A. Ramamurthi A surface-tethered model to assess size-specific effects of hyaluronan (HA) on endothelial cells Biomaterials 28 5 2007 825 835
46. S. Ibrahim, Q.K. Kang, and A. Ramamurthi The impact of hyaluronic acid oligomer content on physical, mechanical, and biologic properties of divinyl sulfone-crosslinked hyaluronic acid hydrogels Journal of Biomedical Materials Research Part A 94A 2 2010 355 370
47. R. Jakobsen, A. Shahdadfar, F. Reinholt, and J. Brinchmann Chondrogenesis in a hyaluronic acid scaffold: comparison between chondrocytes and MSC from bone marrow and adipose tissue Knee Surgery, Sports Traumatology, Arthroscopy 18 10 2010 1407 1416
48. A.K. Jha, R.A. Hule, T. Jiao, S.S. Teller, R.J. Clifton, and R.L. Duncan Structural analysis and mechanical characterization of hyaluronic acid-based doubly cross-linked networks Macromolecules 42 2 2009 537 546
49. Y. Ji, K. Ghosh, X.Z. Shu, B. Li, J.C. Sokolov, and G.D. Prestwich Electrospun three-dimensional hyaluronic acid nanofibrous scaffolds Biomaterials 27 20 2006 3782 3792
50. D. Jiang, J. Liang, and P. Noble Hyaluronan in tissue injury and repair Annual Review of Cell and Developmental Biology 23 2007 435 461
51. D. Jones Volumizing the face with soft tissue fillers Clinics in Plastic Surgery 38 3 2011 379 390
52. S.-W. Kang, J.-S. Kim, K.-S. Park, B.-H. Cha, J.-H. Shim, and J.Y. Kim Surface modification with fibrin/hyaluronic acid hydrogel on solid-free form-based scaffolds followed by BMP-2 loading to enhance bone regeneration Bone 48 2 2011 298 306
53. V. Kasyanov, J. Hodde, M. Hiles, C. Eisenberg, L. Eisenberg, and L. De Castro Rapid biofabrication of tubular tissue constructs by centrifugal casting in a decellularized natural scaffold with laser-machined micropores Journal of Materials Science: Materials in Medicine 20 1 2009 329 337
54. C.M. Kelleher, and J.P. Vacanti Engineering extracellular matrix through nanotechnology Journal of the Royal Society, Interface/the Royal Society 7 2010 S717 S729
55. H. Kim, K. Kim, I. Park, B. Choi, J. Kim, and M. Kim Hybrid scaffolds composed of hyaluronic acid and collagen for cartilage regeneration Tissue Engineering and Regenerative Medicine 9 2 2012 57 62
56. H. Kim, and R. Valentini Retention and activity of BMP-2 in hyaluronic acid-based scaffolds in vitro Journal of Biomedical Materials Research. Part A 59 2002 573 8584
57. M. Kim, S. Garrity, I.E. Erickson, A.H. Huang, J.A. Burdick, and R.L. Mauck Optimization of macromer density in human MSC-laden hyaluronic acid (HA) hydrogels Bioengineering conference (NEBEC) 2012 38th Annual Northeast 2012 211 212
58. K.R. Kirker, Y. Luo, J.H. Nielson, J. Shelby, and G.D. Prestwich Glycosaminoglycan hydrogel films as bio-interactive dressings for wound healing Biomaterials 23 17 2002 3661 3671
59. W. Knudson, G. Chow, and C.B. Knudson CD44-mediated uptake and degradation of hyaluronan Matrix Biology 21 1 2002 15 23
60. Y.-G. Ko, H.H. Oh, N. Kawazoe, T. Tateishi, and G. Chen Preparation of open porous hyaluronic acid scaffolds for tissue engineering using the ice particulate template method Journal of Biomaterials Science: Polymer Edition 22 1-3 2011 123 138
61. G. Kogan, L. Šoltés, R. Stern, and P. Gemeiner Hyaluronic acid: a natural biopolymer with a broad range of biomedical and industrial applications Biotechnology Letters 29 1 2007 17 25
62. L. Lapcik, L. Lapcik, S.D. Smedt, J. Demeester, and P. Chabrecek Hyaluronan: preparation, styructure, properties and applications Chemical Reviews 98 8 1998 2663 2684
63. C. Laurent, S. Hellstrom, and L. Stenfors Hyaluronic acid reduces connective tissue formation in middle ears filled with absorbable gelatin sponge: an experimental study American Journal of Otolaryngology 7 3 1986 181 186
64. J. Leach, K.A. Bivens, C.W. Patrick, and J.C. Schmidt Photocrosslinked hyaluronic acid hydrogels: natural, biodegradable tissue engineering scaffolds Biotechnology and Bioengineering 82 5 2003 578 589
65. M. Lebourg, R. Sabater Serra, J. Más Estellés, F. Hernández Sánchez, J. Gómez Ribelles, and J. Suay Antón Biodegradable polycaprolactone scaffold with controlled porosity obtained by modified particle-leaching technique Journal of Materials Science: Materials in Medicine 19 5 2008 2047 2053
66. H.A. Leddy, H.A. Awad, and F. Guilak Molecular diffusion in tissue-engineered cartilage constructs: Effects of scaffold material, time, and culture conditions Journal of Biomedical Materials Research Part B: Applied Biomaterials 70B 2 2004 397 406
67. Y. Lei, M. Rahim, Q. Ng, and T. Segura Hyaluronic acid and fibrin hydrogels with concentrated DNA/PEI polyplexes for local gene delivery Journal of Controlled Release 153 3 2011 255 261
68. G. Lisignoli, S. Toneguzzi, N. Zini, A. Piacentini, S. Cristino, and M. Tschon Hyaluronan-based biomaterial (Hyaff-11) as scaffold to support mineralization of bone marrow stromal cells La Chirurgia Degli Organi de Movimento 88 4 2003 363 367
69. Y. Liu, X.Z. Shu, and G.D. Prestwich Osteochondral defect repair with autologous bone marrow-derived mesenchymal stem cells in an injectable, in situ, cross-linked synthetic extracellular matrix Tissue Engineering 12 12 2006 3405 3416
70. Y. Luo, K.R. Kirker, and G.D. Prestwich Modification of natural polymers: hyaluronic acid A. Atala, Methods of tissue engineering 2002 Academic Press San Diego 539 553
71. G. Ma, Y. Liu, D. Fang, J. Chen, C. Peng, and X. Fei Hyaluronic acid/chitosan polyelectrolyte complexes nanofibers prepared by electrospinning Materials Letters 74 0 2012 78 80
72. P.X. Ma Scaffolds for tissue fabrication Materials Today 7 5 2004 30 40
73. P.A. Madurantakam, C.P. Cost, D.G. Simpson, and G.L. Bowlin Science of nanofibrous scaffold fabrication: strategies for next generation tissue-engineering scaffolds Nanomedicine 4 2 2009 193 206
74. F. Manna, M. Dentini, P. Desideri, O.D. Pita, E. Mortilla, and B. Maras Comparative chemical evaluation of two commercially available derivatives of hyaluronic acid (Hylaform from rooster combs and Restylane from streptococcus) used for soft tissue augmentation Journal of the European Academy of Dermatology and Venereology 13 1999 183 192
75. K.S. Masters, D.N. Shah, L.A. Leinwand, and K.S. Anseth Crosslinked hyaluronan scaffolds as a biologically active carrier for valvular interstitial cells Biomaterials 26 15 2005 2517 2525
76. R. Mendichi, and A.G. Schieroni Fractionation and characterization of ultra-high molar mass hyaluronan: 2. On-line size exclusion chromatography methods Polymer 43 23 2002 6115 6121
77. A. Metters, K. Anseth, and C. Bowman Fundamental studies of a novel biodegradable PEG -b- PLA hydrogel Polymer 41 2000 3993 4004
78. K. Meyer, and J.W. Palmer The polysaccharide of the vitreous humor The Journal of the Biological Chemistry 107 1934 629 634
79. E. Milella, E. Brescia, C. Massaro, P.A. Ramires, M.R. Miglietta, and V. Fiori Physio-chemical properties and degradability of non-woven hyaluronan benzylic esters as tissue engineering scaffolds Biomaterials 23 2002 1053 1063
80. L.W. Moreland Intra-articular hyaluronan (hyaluronic acid) and hylans for the treatment of osteoarthritis: mechanisms of action Arthritis Research & Therapy 5 2 2003 54 67
81. B.M. Mossaad, and J.D. Frame Correction of breast contour deformities using polyurethane breast implant capsule in revisional breast surgery Journal of Plastic, Reconstructive & Aesthetic Surgery 65 10 2012 1425 1429
82. R. Murugan, and S. Ramakrishna Design strategies of tissue engineering scaffolds with controlled fiber orientation Tissue Engineering 13 8 2007 1845 1866
83. S. Nair, N.S. Remya, S. Remya, and P.D. Nair A biodegradable in situ injectable hydrogel based on chitosan and oxidized hyaluronic acid for tissue engineering applications Carbohydrate Polymers 85 4 2011 838 844
84. L.J. Nesti, W.J. Li, R.M. Shanti, Y.J. Jiang, W. Jackson, and B.A. Freedman Intervertebral disc tissue engineering using a novel hyaluronic acid-nanofibrous scaffold (HANFS) amalgam Tissue Engineering. Part A 14 9 2008 1527 1537
85. C.M. Nimmo, S.C. Owen, and M.S. Shoichet Diels-Alder click cross-linked hyaluronic acid hydrogels for tissue engineering Biomacromolecules 12 3 2011 824 830
86. F.J. O'Brien Biomaterials & scaffolds for tissue engineering Materials Today 14 3 2011 88 95
87. F. O'Brien, B. Harley, I. Yannas, and L. Gibson The effect of pore size on cell adhesion in collagen-GAG scaffolds Biomaterials 26 4 2005 433 441
88. E.J. Oh, K. Park, K.S. Kim, J. Kim, J.-A. Yang, and J.-H. Kong Target specific and long-acting delivery of protein, peptide, and nucleotide therapeutics using hyaluronic acid derivatives Journal of Controlled Release 141 1 2010 2 12
89. R.A. Oldinski, T.T. Ruckh, M.P. Staiger, K.C. Popat, and S.P. James Dynamic mechanical analysis and biomineralization of hyaluronan-polyethylene copolymers for potential use in osteochondral defect repair Acta Biomaterialia 7 3 2011 1184 1191
90. S. Ouasti, R. Donno, F. Cellesi, M.J. Sherratt, G. Terenghi, and N. Tirelli Network connectivity, mechanical properties and cell adhesion for hyaluronic acid/PEG hydrogels Biomaterials 32 27 2011 6456 6470
91. F.S. Palumbo, G. Pitarresi, A. Albanese, F. Calascibetta, and G. Giammona Self-assembling and auto-crosslinkable hyaluronic acid hydrogels with a fibrillar structure Acta Biomaterialia 6 1 2009 195 204
92. L. Pan, Y. Ren, F. Cui, and Q. Xu Viability and differentiation of neural precursors on hyaluronic acid hydrogel scaffold Journal of Neuroscience Research 87 14 2009 3207 3220
93. J. Park, E. Lim, S. Back, H. Na, Y. Park, and K. Sun Nerve regeneration following spinal cord injury using matrix metalloproteinase-sensitive, hyaluronic acid-based biomimetic hydrogel scaffold containing brain-derived neurotrophic factor Journal of Biomedical Materials Research Part A 93A 3 2010 1091 1099
94. J.K. Park, J.-H. Shim, K.S. Kang, J. Yeom, H.S. Jung, and J.Y. Kim Solid free-form fabrication of tissue-engineering scaffolds with a poly(lactic-co-glycolic acid) grafted hyaluronic acid conjugate encapsulating an intact bone morphogenetic protein-2/poly(ethylene glycol) complex Advanced Functional Materials 21 15 2011 2906 2912
95. K.M. Park, J.-A. Yang, H. Jung, J. Yeom, J.S. Park, and K.-H. Park In situ supramolecular assembly and modular modification of hyaluronic acid hydrogels for 3D cellular engineering ACS Nano 6 4 2012 2960 2968
96. Y.D. Park, N. Tirelli, and J.A. Hubbell Photopolymerized hyaluronic acid-based hydrogels and interpenetrating networks Biomaterials 24 2003 893 900
97. C.-K. Perng, Y.-J. Wang, C.-H. Tsi, and H. Ma In vivo angiogenesis effect of porous collagen scaffold with hyaluronic acid oligosaccharides Journal of Surgical Research 168 1 2011 9 15
98. L. Pescosolido, W. Schuurman, J. Malda, P. Matricardi, F. Alhaique, and T. Coviello Hyaluronic acid and dextran-based semi-IPN hydrogels as biomaterials for bioprinting Biomacromolecules 12 5 2011 1831 1838
99. E. Piskin Biodegradable polymers in medicine G. Scott, Degradable polymers 2002 Kluwer Academic Publishers 343 355
100. G. Prestwich Biomaterials from chemically modified hyaluronan The science of hyaluronan today 2001 http://www.glycoforum.gr.jp/index.htm
101. G. Prestwich Hyaluronic acid-based clinical biomaterials derived for cell and molecule delivery in regenerative medicine Journal of Controlled Release 155 2 2011 193 199
102. G.D. Prestwich, D.M. Marecak, J.F. Marecek, K.P. Vercruysse, and M.R. Ziebell Controlled chemical modification of hyaluronic acid: synthesis, applications, and biodegradation of hydrazide derivatives Journal of Controlled Release 53 1998 93 103
103. G.D. Prestwich, and K.P. Vercruysse Profiles therapeutic applications of hyaluronic acid and hyaluronan derivatives Pharmaceutical Science & Technology Today 1 1 1998 42 43
104. C. Radhakumary, A.M. Nandkumar, and P.D. Nair Hyaluronic acid-g-poly(HEMA) copolymer with potential implications for lung tissue engineering Carbohydrate Polymers 85 2 2011 439 445
105. B.B. Ratliff, T. Ghaly, P. Brudnicki, K. Yasuda, M. Rajdev, and M. Bank Endothelial progenitors encapsulated in bioartificial niches are insulated from systemic cytotoxicity and are angiogenesis competent American Journal of Physiology. Renal Physiology 299 1 2010 F178 F186
106. S. Sahoo, C. Chung, S. Khetan, and J.A. Burdick Hydrolytically degradable hyaluronic acid hydrogels with controlled temporal structures Biomacromolecules 9 4 2008 1088 1092
107. E. Saito, Y. Liu, F. Migneco, and S.J. Hollister Strut size and surface area effects on long-term in vivo degradation in computer designed poly(l-lactic acid) three-dimensional porous scaffolds Acta Biomaterialia 8 7 2012 2568 2577
108. R. Sakai, B. John, M. Okamoto, J.V. Seppälä, J. Vaithilingam, and H. Hussein Fabrication of polylactide-based biodegradable thermoset scaffolds for tissue engineering applications Macromolecular Materials and Engineering 2012 n/a-n/a 10.1002/mame.201100436
109. A. Salustri, and C. Fulop Role of hyaluronan during ovulation and fertilization 1998 http://www.glycoforum.gr.jp
110. C. Schante, G. Zuber, C. Herlin, and T.F. Vandamme Synthesis of N-alanyl-hyaluronamide with high degree of substitution for enhanced resistance to hyaluronidase-mediated digestion Carbohydrate Polymers 86 2 2011 747 752
111. C.E. Schante, G. Zuber, C. Herlin, and T.F. Vandamme Chemical modifications of hyaluronic acid for the synthesis of derivatives for a broad range of biomedical applications Carbohydrate Polymers 85 3 2011 469 489
112. C.E. Schante, G. Zuber, C. Herlin, and T.F. Vandamme Improvement of hyaluronic acid enzymatic stability by the grafting of amino-acids Carbohydrate Polymers 87 3 2012 2211 2216
113. T. Segura Engineering substrate-mediated gene delivery: A novel DNA delivery strategy 2004 Northwestern University EVANSTON, ILLINOIS
114. S.K. Seidlits, C.T. Drinnan, R.R. Petersen, J.B. Shear, L.J. Suggs, and C.E. Schmidt Fibronectin-hyaluronic acid composite hydrogels for three-dimensional endothelial cell culture Acta Biomaterialia 7 6 2011 2401 2409
115. M.S. Shoichet Polymer scaffolds for biomaterials applications Macromolecules 43 2 2009 581 591
116. V.I. Sikavitsas, J.S. Temenoff, and A.G. Mikos Biomaterials and bone mechanotransduction Biomaterials 22 19 2001 2581 2593
117. A. Skardal, Z. Jianxing, L. McCoard, X. Xu, O. Siam, and G.D. Prestwich Photocrosslinkable hyaluronan-gelatin hydrogels for two-step bioprinting Tissue Engineering Part A 16 8 2010 2675 2685
118. B.V. Slaughter, S.S. Khurshid, O.Z. Fisher, A. Khademhosseini, and N.A. Peppas Hydrogels in regenerative medicine Advanced Materials 21 2009 3307 3329
119. M. Solis, C. Ying-Hui, W. Tzyy Yue, Z.B. Vanessa, Y.-C. Lin, and L.L.H. Huang Hyaluronan regulates cell behavior: a potential Niche matrix for stem cells Biochemistry Research International 2012 2012 1 11
120. J.-K.F. Suh, and H.W.T. Matthew Application of chitosan-based polysaccharide biomaterials in cartilage tissue engineering: a review Biomaterials 21 2000 2589 2598
121. S. Suri, L.-H. Han, W. Zhang, A. Singh, S. Chen, and C. Schmidt Solid freeform fabrication of designer scaffolds of hyaluronic acid for nerve tissue engineering Biomedical Microdevices 13 6 2011 983 993
122. S. Suri, and C.E. Schmidt Photopatterned collagen-hyaluronic acid interpenetrating polymer network hydrogels Acta Biomaterialia 5 2009 2385
123. S. Takahashi, H. Yamazoe, F. Sassa, H. Suzuki, and J. Fukuda Preparation of coculture system with three extracellular matrices using capillary force lithography and layer-by-layer deposition Journal of Bioscience and Bioengineering 108 6 2009 544 550
124. K. Takeda, N. Sakai, H. Shiba, T. Nagahara, T. Fujita, and M. Kajiya Characteristics of high-molecular-weight hyaluronic acid as a brain-derived neurotrophic factor scaffold in periodontal tissue regeneration Tissue Engineering Part A 17 7-8 2011 955 967
125. H. Tan, C.R. Chu, K.A. Payne, and K.G. Marra Injectable in situ forming biodegradable chitosan-hyaluronic acid based hydrogels for cartilage tissue engineering Biomaterials 30 13 2009 2499 2506
126. B.M. Teh, Y. Shen, P.L. Friedland, M.D. Atlas, and R.J. Marano A review on the use of hyaluronic acid in tympanic membrane wound healing Expert Opinion on Biological Therapy 12 1 2012 23 36
127. W.S. Toh, T.C. Lim, M. Kurisawa, and M. Spector Modulation of mesenchymal stem cell chondrogenesis in a tunable hyaluronic acid hydrogel microenvironment Biomaterials 33 15 2012 3835 3845
128. K. Tomihata, and Y. Ikada Crosslinking of hyaluronic acid with glutaraldehyde Journal of Polymer Science Part A: Polymer Chemistry 35 1997 3553 3559
129. E. Turley RHAMM, a member of the hyaladherins The science of hyaluronan today 1999 http://www.glycoforum.gr.jp/index.htm
130. S. Van Vlierberghe, P. Dubruel, and E. Schacht Biopolymer-based hydrogels as scaffolds for tissue engineering applications: A review Biomacromolecules 12 5 2011 1387 1408
131. J. Venugopal, S. Low, A.T. Choon, and S. Ramakrishna Interaction of cells and nanofiber scaffolds in tissue engineering Journal of Biomedical Materials Research Part B: Applied Biomaterials 84B 1 2008 34 48
132. T.-W. Wang, and M. Spector Development of hyaluronic acid-based scaffolds for brain tissue engineering Acta Biomaterialia 5 7 2009 2371 2384
133. X. Wang, He. Jin, Y. Wang, and F.-Z. Cui Hyaluronic acid-based scaffold for central neural tissue engineering Interface Focus 2 3 2012 278 291
134. W. Wong, and D. Mooney Synthesis and properties of biodegradable polymers used as synthetic matrices for tissue engineering A. Atala, D. Mooney, Synthetic biodegradable polymer scaffolds 1997 Birkhauser Boston 51 82
135. X. Xu, A.K. Jha, R.L. Duncan, and X. Jia Heparin-decorated, hyaluronic acid-based hydrogel particles for the controlled release of bone morphogenetic protein 2 Acta Biomaterialia 7 8 2011 3050 3059
136. Y. Yeo, C.B. Highley, E. Bellas, T. Ito, R. Marini, and R. Langer In situ cross-linkable hyaluronic acid hydrogels prevent post-operative abdominal adhesions in a rabbit model Biomaterials 27 27 2006 4698 4705
137. I.-S. Yoon, C.W. Chung, J.-H. Sung, H.-J. Cho, J.S. Kim, and W.-S. Shim Proliferation and chondrogenic differentiation of human adipose-derived mesenchymal stem cells in porous hyaluronic acid scaffold Journal of Bioscience and Bioengineering 112 4 2010 402 408
138. S.A. Zawko, S. Suri, Q. Truong, and C.E. Schmidt Photopatterned anisotropic swelling of dual-crosslinked hyaluronic acid hydrogels Acta Biomaterialia 5 1 2009 14 22
139. F. Zhang, C. He, L. Cao, W. Feng, H. Wang, and X. Mo Fabrication of gelatin-hyaluronic acid hybrid scaffolds with tunable porous structures for soft tissue engineering International Journal of Biological Macromolecules 48 3 2011 474 481
140. J. Zhang, L. Wu, D. Jing, and J. Ding A comparative study of porous scaffolds with cubic and spherical macropores Polymer 46 13 2005 4979 4985
141. L.-M. Zhang, C.-X. Wu, J.-Y. Huang, X.-H. Peng, P. Chen, and S.-Q. Tang Synthesis and characterization of a degradable composite agarose/HA hydrogel Carbohydrate Polymers 88 4 2012 1445 1452
142. L. Zhang, K. Li, W. Xiao, L. Zheng, Y. Xiao, and H. Fan Preparation of collagen-chondroitin sulfate-hyaluronic acid hybrid hydrogel scaffolds and cell compatibility in vitro Carbohydrate Polymers 84 1 2010 118 125
143. L. Zhang, Y. Xiao, B. Jiang, H. Fan, and X. Zhang Effect of adipic dihydrazide modification on the performance of collagen/hyaluronic acid scaffold Journal of Biomedical Materials Research Part B: Applied Biomaterials 92B 2 2010 307 316
144. W. Zhang, and S. Chen Femtosecond laser nanofabrication of hydrogel biomaterial MRS Bulletin 36 2011 1028 1033
145. J. Zhong, A. Chan, L. Morad, H.I. Kornblum, F. Guoping, and S.T. Carmichael Hydrogel matrix to support stem cell survival after brain transplantation in stroke Neurorehabilitation and Neural Repair 24 7 2010 636 644