Structural Organization of Mammalian Prions as Probed by Limited Proteolysis

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Vázquez Fernández, Ester ^a   Alonso, Jana ^b   Pastrana, Miguel A ^a   Ramos, Adriana ^a   Stitz, Lothar ^c   Vidal, Enric ^d   Dynin, Irina ^e   Petsch, Benjamin ^c   Silva, Christopher J ^e   Requena, Jesús R ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b Santiago University Clinical Hospital   (Spain)

^c FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

^d CENTRE DE RECERCA EN SANITAT ANIMAL CRESA   (Spain)

^e WESTERN REGIONAL RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSYLPHOSPHATIDYLINOSITOL; POLYMER; PRION PROTEIN; PROTEINASE K; SUGAR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BETA SHEET; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME LOCALIZATION; ENZYME METABOLISM; FEMALE; LIPID MEMBRANE; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN POLYMORPHISM; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

ANIMALS; BLOTTING, WESTERN; ENDOPEPTIDASE K; FEMALE; GENE EXPRESSION; GLYCOSYLPHOSPHATIDYLINOSITOLS; MICE; MICE, TRANSGENIC; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, SECONDARY; PROTEOLYSIS; PRPSC PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

ANIMALIA; MAMMALIAN PRION; MUS MUSCULUS;

EID: 84869785863     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0050111     Document Type: Article

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