Survival of Cancer Stem Cells under Hypoxia and Serum Depletion via Decrease in PP2A Activity and Activation of p38-MAPKAPK2-Hsp27

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Lin, Shih Pei ^a,b   Lee, Yi Ting ^a,b   Wang, Jir You ^a,b   Miller, Stephanie A ^c   Chiou, Shih Hwa ^a,b   Hung, Mien Chie ^c,d   Hung, Shih Chieh ^a,b  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 9; CD133 ANTIGEN; HEAT SHOCK PROTEIN 27; MITOGEN ACTIVATED PROTEIN KINASE P38; NESTIN; OCTAMER TRANSCRIPTION FACTOR 4; PHOSPHOPROTEIN PHOSPHATASE 2A; TRANSCRIPTION FACTOR CDX2; TRANSCRIPTION FACTOR NANOG; VASCULOTROPIN;

APOPTOSIS; ARTICLE; CANCER STEM CELL; CELL DIFFERENTIATION; CELL GROWTH; CELL POPULATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYPOXIA; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPHEROID CELL;

ANIMALS; ANOXIA; ANTIGENS, CD; APOPTOSIS; CASPASE 3; CASPASE 9; CELL LINE, TUMOR; CELL MOVEMENT; CELL SURVIVAL; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOPROTEINS; HSP27 HEAT-SHOCK PROTEINS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, SCID; NEOPLASM INVASIVENESS; NEOPLASTIC STEM CELLS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDES; PROTEIN PHOSPHATASE 2; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TYROSINE;

EID: 84869778648     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0049605     Document Type: Article

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