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Volumn 24, Issue 4, 2012, Pages 151-159

Bladder cancer and schistosomiasis

Author keywords

Bilharziasis; Biology; Bladder cancer; Chemotherapy; Cytogenetics; Pathology; Radical cystectomy; Radiotherapy; Schistosomiasis

Indexed keywords

CISPLATIN; DOXORUBICIN; EPIRUBICIN; GEMCITABINE; METHOTREXATE; MITOMYCIN C; VINBLASTINE;

EID: 84869774895     PISSN: 11100362     EISSN: 16879996     Source Type: Journal    
DOI: 10.1016/j.jnci.2012.08.002     Document Type: Review
Times cited : (63)

References (101)
  • 2
    • 80051580618 scopus 로고    scopus 로고
    • Cancer statistics 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer death
    • Siegel R., Ward E., Brawkey O., Jamal A. Cancer statistics 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer death. CA Cancer J Clin 2011, 61:212-236.
    • (2011) CA Cancer J Clin , vol.61 , pp. 212-236
    • Siegel, R.1    Ward, E.2    Brawkey, O.3    Jamal, A.4
  • 3
    • 51649127504 scopus 로고    scopus 로고
    • Muscle invasive bladder cancer in upper Egypt: the shift in risk factors and tumor characteristics
    • Zarzour A.H., Selim M., Abd-Elsayed A.A., Hameed D.A., Abdelaziz M.A. Muscle invasive bladder cancer in upper Egypt: the shift in risk factors and tumor characteristics. BMC cancer 2008, 8:250.
    • (2008) BMC cancer , vol.8 , pp. 250
    • Zarzour, A.H.1    Selim, M.2    Abd-Elsayed, A.A.3    Hameed, D.A.4    Abdelaziz, M.A.5
  • 4
    • 33750076118 scopus 로고    scopus 로고
    • Histologic variants of urothelial carcinoma: differential diagnosis and clinical implications
    • Lopez-Beltran A., Cheng L. Histologic variants of urothelial carcinoma: differential diagnosis and clinical implications. Hum Pathol 2006, 37:1371-1388.
    • (2006) Hum Pathol , vol.37 , pp. 1371-1388
    • Lopez-Beltran, A.1    Cheng, L.2
  • 5
    • 0033858985 scopus 로고    scopus 로고
    • Comparison of genetic changes in schistosome-related transitional and squamous bladder cancers using comparative genomic hybridization
    • Muscheck M., Abol-Enein H., Chew K., et al. Comparison of genetic changes in schistosome-related transitional and squamous bladder cancers using comparative genomic hybridization. Carcinogenesis 2000, 21:1721-1726.
    • (2000) Carcinogenesis , vol.21 , pp. 1721-1726
    • Muscheck, M.1    Abol-Enein, H.2    Chew, K.3
  • 6
    • 0026495364 scopus 로고
    • Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors
    • Kallioniemi A., Kallioniemi O.P., Sudar D., et al. Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors. Science 1992, 258:818-821.
    • (1992) Science , vol.258 , pp. 818-821
    • Kallioniemi, A.1    Kallioniemi, O.P.2    Sudar, D.3
  • 8
    • 0033831517 scopus 로고    scopus 로고
    • Infections as a major preventable cause of human cancer
    • Kuper H., Adami H.O., Trichopoulos D. Infections as a major preventable cause of human cancer. J Intern Med 2000, 248:171-183.
    • (2000) J Intern Med , vol.248 , pp. 171-183
    • Kuper, H.1    Adami, H.O.2    Trichopoulos, D.3
  • 10
    • 79955411065 scopus 로고    scopus 로고
    • Helminths in human carcinogenesis
    • Fried B., Reddy A., Mayer D. Helminths in human carcinogenesis. Cancer Lett 2011, 305(2):239-249.
    • (2011) Cancer Lett , vol.305 , Issue.2 , pp. 239-249
    • Fried, B.1    Reddy, A.2    Mayer, D.3
  • 12
    • 0001988230 scopus 로고
    • Associated bilharziasis and primary malignant disease of the urinary bladder with observations on a series of forty cases
    • Ferguson A.R. Associated bilharziasis and primary malignant disease of the urinary bladder with observations on a series of forty cases. J Pathol Bacteriol 1911, 16:76-94.
    • (1911) J Pathol Bacteriol , vol.16 , pp. 76-94
    • Ferguson, A.R.1
  • 13
    • 84869859285 scopus 로고    scopus 로고
    • Ministry of Health and Population, Department of Endemic Diseases, Prevalence of schistosomiasis in Egypt over time, Egypt,.
    • Ministry of Health and Population, Department of Endemic Diseases, Prevalence of schistosomiasis in Egypt over time, Egypt, 2004.
    • (2004)
  • 15
    • 0028281021 scopus 로고
    • Involvement of inflammatory reactions and elevated cell proliferation in the development of bladder cancer in schistosomiasis patients
    • Rosin M.P., Saad el Din Zaki S., Ward A.J., Anwar W.A. Involvement of inflammatory reactions and elevated cell proliferation in the development of bladder cancer in schistosomiasis patients. Mutat Res 1994, 305:83-92.
    • (1994) Mutat Res , vol.305 , pp. 83-92
    • Rosin, M.P.1    Saad el Din Zaki, S.2    Ward, A.J.3    Anwar, W.A.4
  • 16
    • 0023685375 scopus 로고
    • Mammalian synthesis of nitrite, nitrate, nitric oxide, and nitrosating agents
    • Marletta M.A. Mammalian synthesis of nitrite, nitrate, nitric oxide, and nitrosating agents. Chem Res Toxicol 1988, 1:249-257.
    • (1988) Chem Res Toxicol , vol.1 , pp. 249-257
    • Marletta, M.A.1
  • 17
    • 0346501807 scopus 로고    scopus 로고
    • Squamous cell carcinoma of the bladder: pathology, diagnosis and treatment
    • Shokeir A.A. Squamous cell carcinoma of the bladder: pathology, diagnosis and treatment. BJU Int 2004, 93:216-220.
    • (2004) BJU Int , vol.93 , pp. 216-220
    • Shokeir, A.A.1
  • 18
    • 36549004227 scopus 로고
    • Monograph on the evaluation of carcinogenic risks to humans: schistosomes, liver flukes and Helicobacter pylori
    • IARC
    • Monograph on the evaluation of carcinogenic risks to humans: schistosomes, liver flukes and Helicobacter pylori. WHO: International Agency for Research on Cancer 1994, 61:9-175. IARC.
    • (1994) WHO: International Agency for Research on Cancer , vol.61 , pp. 9-175
  • 19
    • 0022547804 scopus 로고
    • The pathobiology of Schistosoma haematobium infection in humans
    • Smith J.H., Christie J.D. The pathobiology of Schistosoma haematobium infection in humans. Hum Pathol 1986, 17:333-345.
    • (1986) Hum Pathol , vol.17 , pp. 333-345
    • Smith, J.H.1    Christie, J.D.2
  • 20
    • 0019857558 scopus 로고
    • The impact of schistosomiasis on the pathology of bladder carcinoma
    • El-Bolkainy M.N., Mokhtar N.M., Ghonim M.A., Hussein M.H. The impact of schistosomiasis on the pathology of bladder carcinoma. Cancer 1981, 48:2643-2648.
    • (1981) Cancer , vol.48 , pp. 2643-2648
    • El-Bolkainy, M.N.1    Mokhtar, N.M.2    Ghonim, M.A.3    Hussein, M.H.4
  • 22
    • 25444467767 scopus 로고    scopus 로고
    • Urothelial tumorigenesis: a tale of divergent pathway
    • Wu X.R. Urothelial tumorigenesis: a tale of divergent pathway. Nat Rev Cancer 2005, 5:713-725.
    • (2005) Nat Rev Cancer , vol.5 , pp. 713-725
    • Wu, X.R.1
  • 23
    • 77954899218 scopus 로고    scopus 로고
    • Schistosoma hematobium and bladder cancer
    • Botelho M.C., Machado J.C., de Costa J.M. Schistosoma hematobium and bladder cancer. Virulence 2010, 1(2):84-87.
    • (2010) Virulence , vol.1 , Issue.2 , pp. 84-87
    • Botelho, M.C.1    Machado, J.C.2    de Costa, J.M.3
  • 24
    • 77954683305 scopus 로고    scopus 로고
    • Bladder cancer in 2010: how far have we come?
    • Jacobs B.L., Lee C.T., Montie J.E. Bladder cancer in 2010: how far have we come?. CA Cancer J Clin 2010, 60(4):244-272.
    • (2010) CA Cancer J Clin , vol.60 , Issue.4 , pp. 244-272
    • Jacobs, B.L.1    Lee, C.T.2    Montie, J.E.3
  • 25
    • 77953847133 scopus 로고    scopus 로고
    • Molecular genetics of bladder cancer: emerging mechanisms of tumor initiation and progression
    • Mc Conkey D.J., Lee S., Choi W., et al. Molecular genetics of bladder cancer: emerging mechanisms of tumor initiation and progression. Urol Oncol 2010, 28(4):429-440.
    • (2010) Urol Oncol , vol.28 , Issue.4 , pp. 429-440
    • Mc Conkey, D.J.1    Lee, S.2    Choi, W.3
  • 26
    • 39049182237 scopus 로고    scopus 로고
    • Role of loss of heterozygosity on chromosomes 8 and 9 in the development and progression of cancer bladder
    • Abdel Wahab A.H., Abo-Zeid H.I., El-Husseini M.I., Ismail M., El-Khor A.M. Role of loss of heterozygosity on chromosomes 8 and 9 in the development and progression of cancer bladder. J Egypt Natl Canc Inst 2005, 17(4):260-269.
    • (2005) J Egypt Natl Canc Inst , vol.17 , Issue.4 , pp. 260-269
    • Abdel Wahab, A.H.1    Abo-Zeid, H.I.2    El-Husseini, M.I.3    Ismail, M.4    El-Khor, A.M.5
  • 27
    • 0031400916 scopus 로고    scopus 로고
    • Expression of bcl-2 and p53 oncoproteins in schistosomiasis-associated transitional and squamous cell carcinoma of the urinary bladder
    • Chaudhary K.S., Lu K.S., Abel P.D., et al. Expression of bcl-2 and p53 oncoproteins in schistosomiasis-associated transitional and squamous cell carcinoma of the urinary bladder. Br J Urol 1997, 79:78-84.
    • (1997) Br J Urol , vol.79 , pp. 78-84
    • Chaudhary, K.S.1    Lu, K.S.2    Abel, P.D.3
  • 28
    • 0035698885 scopus 로고    scopus 로고
    • Cyclooxygenase-2: a possible target in Schistosoma associated bladder cancer
    • El-Sheikh S.S., Madaan S., Alhasso A., Abel P., Stamp G., Lalani E.N. Cyclooxygenase-2: a possible target in Schistosoma associated bladder cancer. Br J Urol 2001, 88:921-927.
    • (2001) Br J Urol , vol.88 , pp. 921-927
    • El-Sheikh, S.S.1    Madaan, S.2    Alhasso, A.3    Abel, P.4    Stamp, G.5    Lalani, E.N.6
  • 29
    • 0032506745 scopus 로고    scopus 로고
    • Early acquisition of homozygous deletions of p16/p19 during squamous cell carcinogenesis and genetic mosaicism in bladder cancer
    • Tsutsumi M., Tsai Y.C., Gonzalgo M.L., Nichols P.W., Jones P.A. Early acquisition of homozygous deletions of p16/p19 during squamous cell carcinogenesis and genetic mosaicism in bladder cancer. Oncogene 1998, 17:3021-3027.
    • (1998) Oncogene , vol.17 , pp. 3021-3027
    • Tsutsumi, M.1    Tsai, Y.C.2    Gonzalgo, M.L.3    Nichols, P.W.4    Jones, P.A.5
  • 30
    • 3042759837 scopus 로고    scopus 로고
    • Chromosomal aberrations in benign and malignant bilharzia-associated bladder lesions analyzed by comparative genomic hybridization
    • Fadl-Elmula I., Kytola S., Leithy M.E., et al. Chromosomal aberrations in benign and malignant bilharzia-associated bladder lesions analyzed by comparative genomic hybridization. BMC Cancer 2002, 2:5.
    • (2002) BMC Cancer , vol.2 , pp. 5
    • Fadl-Elmula, I.1    Kytola, S.2    Leithy, M.E.3
  • 31
    • 34547744399 scopus 로고    scopus 로고
    • Genomic imbalances in Schistosoma-associated and non Schistosoma-associated bladder carcinoma: an array comparative genomic hybridization analysis
    • Armengol G., Eissa S., Lozano J.J., et al. Genomic imbalances in Schistosoma-associated and non Schistosoma-associated bladder carcinoma: an array comparative genomic hybridization analysis. Cancer Genet Cytogenet 2007, 177:16-19.
    • (2007) Cancer Genet Cytogenet , vol.177 , pp. 16-19
    • Armengol, G.1    Eissa, S.2    Lozano, J.J.3
  • 32
    • 34548543757 scopus 로고    scopus 로고
    • Can bladder adenocarcinomas be distinguished from schistosomiasis associated bladder cancer by using comparative genomic hybridization analysis?
    • Vauhkonen H., Bohling T., Eissa S., Shoman S., Knuutila S. Can bladder adenocarcinomas be distinguished from schistosomiasis associated bladder cancer by using comparative genomic hybridization analysis?. Cancer Genet Cytogen 2007, 177:153-157.
    • (2007) Cancer Genet Cytogen , vol.177 , pp. 153-157
    • Vauhkonen, H.1    Bohling, T.2    Eissa, S.3    Shoman, S.4    Knuutila, S.5
  • 34
    • 84862990351 scopus 로고    scopus 로고
    • The bladder cancer genome: chromosomal changes as prognostic markers, opportunities and obstacles
    • Hogland M. The bladder cancer genome: chromosomal changes as prognostic markers, opportunities and obstacles. Urol Oncol 2012, 30:535-540.
    • (2012) Urol Oncol , vol.30 , pp. 535-540
    • Hogland, M.1
  • 35
    • 84862750901 scopus 로고    scopus 로고
    • Cytogenetic profile of locally advanced and metastatic Schistosoma-related bladder cancer and response to chemotherapy
    • Aly M.S., Khaled H.M., Emara M., Hussein T.D. Cytogenetic profile of locally advanced and metastatic Schistosoma-related bladder cancer and response to chemotherapy. CancerGenet 2012, 205(4):156-162.
    • (2012) CancerGenet , vol.205 , Issue.4 , pp. 156-162
    • Aly, M.S.1    Khaled, H.M.2    Emara, M.3    Hussein, T.D.4
  • 36
    • 34249785713 scopus 로고    scopus 로고
    • Chromosomal deletions in bladder cancer: shutting down pathways
    • Abraham R., Pagano F., Gonella L.G., et al. Chromosomal deletions in bladder cancer: shutting down pathways. Front Biosci 2007, 12:826-838.
    • (2007) Front Biosci , vol.12 , pp. 826-838
    • Abraham, R.1    Pagano, F.2    Gonella, L.G.3
  • 37
    • 0028839274 scopus 로고
    • El-Sadr. Changing age incidence and pathological types of schistosoma-associated bladder carcinoma
    • Koraitim M.M., Metwalli N.E., Atta M.A. El-Sadr. Changing age incidence and pathological types of schistosoma-associated bladder carcinoma. J Urol 1995, 154:1714-1716.
    • (1995) J Urol , vol.154 , pp. 1714-1716
    • Koraitim, M.M.1    Metwalli, N.E.2    Atta, M.A.3
  • 38
    • 77949909981 scopus 로고    scopus 로고
    • Time-trend in epidemiological and pathological features of schistosoma-associated bladder cancer
    • Zaghloul M.S., Nouh A., Moneer M., El-Baradie M., Nazmy M., Younis A. Time-trend in epidemiological and pathological features of schistosoma-associated bladder cancer. J Egypt Natl Canc Inst 2008, 20(2):168-174.
    • (2008) J Egypt Natl Canc Inst , vol.20 , Issue.2 , pp. 168-174
    • Zaghloul, M.S.1    Nouh, A.2    Moneer, M.3    El-Baradie, M.4    Nazmy, M.5    Younis, A.6
  • 39
    • 84856729701 scopus 로고    scopus 로고
    • Changing patterns (age, incidence and pathological types) of schistosoma-associated bladder cancer in Egypt in the past decade
    • Salem H.K., Mahfouz S. Changing patterns (age, incidence and pathological types) of schistosoma-associated bladder cancer in Egypt in the past decade. Urology 2012, 79(2):379-383.
    • (2012) Urology , vol.79 , Issue.2 , pp. 379-383
    • Salem, H.K.1    Mahfouz, S.2
  • 40
    • 0028196842 scopus 로고
    • Radiation as adjunctive therapy to cystectomy for bladder cancer.Is there a difference for bilharzial association?
    • Zaghloul M.S. Radiation as adjunctive therapy to cystectomy for bladder cancer.Is there a difference for bilharzial association?. Int. J. Radiat. Oncol. Biol. Phys. 1994, 28:783.
    • (1994) Int. J. Radiat. Oncol. Biol. Phys. , vol.28 , pp. 783
    • Zaghloul, M.S.1
  • 41
    • 0030020779 scopus 로고    scopus 로고
    • Distant metastasis from bilharzial bladder cancer
    • Zaghloul M.S. Distant metastasis from bilharzial bladder cancer. Cancer 1996, 77:743-749.
    • (1996) Cancer , vol.77 , pp. 743-749
    • Zaghloul, M.S.1
  • 42
    • 0017355483 scopus 로고
    • Bladder cancer. Superiority of preoperative irradiation and cystectomy in clinical stages B2 and C
    • Miller L.S. Bladder cancer. Superiority of preoperative irradiation and cystectomy in clinical stages B2 and C. Cancer 1977, 39:973-980.
    • (1977) Cancer , vol.39 , pp. 973-980
    • Miller, L.S.1
  • 43
    • 84869857241 scopus 로고
    • Carcinoma of the urinary bladder T3 Nx MO treated by preoperative irradiation followed by simples cystectomy
    • Werf-Messing B.V., Friedell G.H., Menon R.S., Raigopa S.M. Carcinoma of the urinary bladder T3 Nx MO treated by preoperative irradiation followed by simples cystectomy. IntJ Radiclt Oiicol Biol Phys 1982, 1847-1855.
    • (1982) IntJ Radiclt Oiicol Biol Phys , pp. 1847-1855
    • Werf-Messing, B.V.1    Friedell, G.H.2    Menon, R.S.3    Raigopa, S.M.4
  • 44
    • 0026520172 scopus 로고
    • Local recurrence after cystectomy alone for bladder carcinoma
    • Greven K.M., Spera J.A., Solin L.W. Local recurrence after cystectomy alone for bladder carcinoma. Cancer 1992, 69:2767-2770.
    • (1992) Cancer , vol.69 , pp. 2767-2770
    • Greven, K.M.1    Spera, J.A.2    Solin, L.W.3
  • 45
    • 20444482036 scopus 로고    scopus 로고
    • Local recurrence after cystectomy and survival of patients with bladder cancer: a population based study in greater Amsterdam
    • Visser O., Nieuwenhuijzen J.A., Horenblas S. Local recurrence after cystectomy and survival of patients with bladder cancer: a population based study in greater Amsterdam. J Urol 2005, 174:97-102.
    • (2005) J Urol , vol.174 , pp. 97-102
    • Visser, O.1    Nieuwenhuijzen, J.A.2    Horenblas, S.3
  • 46
    • 0034656998 scopus 로고    scopus 로고
    • Predicting the survival of bladder carcinoma patients treated with radical cystectomy
    • Cheng L., Weaver A.L., Leibovich B.C., et al. Predicting the survival of bladder carcinoma patients treated with radical cystectomy. Cancer 2000, 88:2326-2332.
    • (2000) Cancer , vol.88 , pp. 2326-2332
    • Cheng, L.1    Weaver, A.L.2    Leibovich, B.C.3
  • 47
    • 62149133484 scopus 로고    scopus 로고
    • Oncological followup after radical cystectomy for bladder cancer - is there any benefit?
    • Volkmer B.G., Kuefer R., Bartsch G.C., et al. Oncological followup after radical cystectomy for bladder cancer - is there any benefit?. J. Urol. 2009, 181(4):1587-1593.
    • (2009) J. Urol. , vol.181 , Issue.4 , pp. 1587-1593
    • Volkmer, B.G.1    Kuefer, R.2    Bartsch, G.C.3
  • 48
    • 38349124442 scopus 로고    scopus 로고
    • Radical cystectomy for bladder cancer: a single center experience
    • Gupta N.P., Kolla S.B., Seth A., et al. Radical cystectomy for bladder cancer: a single center experience. Indian J. Urol 2008, 24(1):54-59.
    • (2008) Indian J. Urol , vol.24 , Issue.1 , pp. 54-59
    • Gupta, N.P.1    Kolla, S.B.2    Seth, A.3
  • 49
    • 13344294831 scopus 로고
    • Bilharzial bladder cancer in Egypt. A review of 420 cases of radical cystectomy. Jap
    • El-Said A., Omar S., Ibrahim A.S., et al. Bilharzial bladder cancer in Egypt. A review of 420 cases of radical cystectomy. Jap. J Clin Oncol 1979, 9:117-122.
    • (1979) J Clin Oncol , vol.9 , pp. 117-122
    • El-Said, A.1    Omar, S.2    Ibrahim, A.S.3
  • 50
    • 0026691124 scopus 로고
    • Postoperative radiotherapy of carcinoma in bilharzial bladder. Improved disease-free survival through improving local control
    • Zaghloul M.S., Awwad H.K., Omar S., et al. Postoperative radiotherapy of carcinoma in bilharzial bladder. Improved disease-free survival through improving local control. Int. J. Radiat. Oncol. Biol. Phys. 1992, 22:511-517.
    • (1992) Int. J. Radiat. Oncol. Biol. Phys. , vol.22 , pp. 511-517
    • Zaghloul, M.S.1    Awwad, H.K.2    Omar, S.3
  • 51
    • 38149067795 scopus 로고    scopus 로고
    • Adjuvant radiation therapy for locally advanced bladder cancer
    • Zaghloul M.S. Adjuvant radiation therapy for locally advanced bladder cancer. Touchbriefings, US oncological disease issue 2006, 2:86-89.
    • (2006) Touchbriefings, US oncological disease issue , vol.2 , pp. 86-89
    • Zaghloul, M.S.1
  • 52
    • 0030814787 scopus 로고    scopus 로고
    • Radical cystectomy for carcinoma of the bladder: critical evaluation of the results in 1,026 cases
    • Ghoneim M.A., El-Mekresh M.M., El-Baz M.A., El-Attar I.A., Ashamallah A. Radical cystectomy for carcinoma of the bladder: critical evaluation of the results in 1,026 cases. J Urol 1997, 158:393-399.
    • (1997) J Urol , vol.158 , pp. 393-399
    • Ghoneim, M.A.1    El-Mekresh, M.M.2    El-Baz, M.A.3    El-Attar, I.A.4    Ashamallah, A.5
  • 53
    • 44649152238 scopus 로고    scopus 로고
    • El-Mekresh M et al.: Radical cystectomy for carcinoma of the bladder: 2,720 consecutive cases 5 year later
    • Ghoneim M.A., Abdel-Latif M. El-Mekresh M et al.: Radical cystectomy for carcinoma of the bladder: 2,720 consecutive cases 5 year later. J. Urol. 2008, 180(1):121-127.
    • (2008) J. Urol. , vol.180 , Issue.1 , pp. 121-127
    • Ghoneim, M.A.1    Abdel-Latif, M.2
  • 54
    • 84871057839 scopus 로고    scopus 로고
    • Guidelines on TaT1 (non-muscle invasive) bladder cancer.European Association of Urology Web site. August 5,2012.
    • Babjuk M, Oosterlinck W, Sylvester R, Kaasinen E, Böhle A, Palou J. Guidelines on TaT1 (non-muscle invasive) bladder cancer.European Association of Urology Web site. http://www.uroweb.org/professional resources/guidelines/online accessed August 5,2012.
    • Babjuk, M.1    Oosterlinck, W.2    Sylvester, R.3    Kaasinen, E.4    Böhle, A.5    Palou, J.6
  • 55
    • 77949487097 scopus 로고    scopus 로고
    • Detrusor muscle in the first, apparently complete transurethral resection of the bladder tumour specimen is a surrogate marker of resection quality, predicts risk of early recurrence and is dependent on operator experience
    • Mariappan P., Zachou A., Grigor K.M. Detrusor muscle in the first, apparently complete transurethral resection of the bladder tumour specimen is a surrogate marker of resection quality, predicts risk of early recurrence and is dependent on operator experience. Eur Urol 2010, 57(5):843-849.
    • (2010) Eur Urol , vol.57 , Issue.5 , pp. 843-849
    • Mariappan, P.1    Zachou, A.2    Grigor, K.M.3
  • 56
    • 0038152768 scopus 로고    scopus 로고
    • Effect of routine repeat transurethral resection for superficial bladder cancer
    • Grimm M., Steinhoff Ch., Simon X., et al. Effect of routine repeat transurethral resection for superficial bladder cancer. A long-term observation study. J Urol 2003, 170:433-437.
    • (2003) A long-term observation study. J Urol , vol.170 , pp. 433-437
    • Grimm, M.1    Steinhoff, C.2    Simon, X.3
  • 57
    • 67649431728 scopus 로고    scopus 로고
    • An individual patient data metaanalysis of the long-term outcome of randomized studies comparing intravesical mitomycin C versus bacillus calmette-guerin for non-muscle=invasive bladder cancer
    • Malmstrom P., Sylvester R.J., Crawford D.E., et al. An individual patient data metaanalysis of the long-term outcome of randomized studies comparing intravesical mitomycin C versus bacillus calmette-guerin for non-muscle=invasive bladder cancer. Eur Urol 2009, 56(2):247-256.
    • (2009) Eur Urol , vol.56 , Issue.2 , pp. 247-256
    • Malmstrom, P.1    Sylvester, R.J.2    Crawford, D.E.3
  • 58
    • 84869747523 scopus 로고    scopus 로고
    • Bladder cancer and schistosomiasis: Is there a difference for the association
    • In Tech open publisher, Rajeko, Croatia, A.E. Canda (Ed.)
    • Zaghloul M.S., Gouda I. Bladder cancer and schistosomiasis: Is there a difference for the association. Bladder cancer- ftom basic science to robotic surgery 2012, 195-218. In Tech open publisher, Rajeko, Croatia. A.E. Canda (Ed.).
    • (2012) Bladder cancer- ftom basic science to robotic surgery , pp. 195-218
    • Zaghloul, M.S.1    Gouda, I.2
  • 59
    • 80053081007 scopus 로고    scopus 로고
    • Survival after primary and deferred cystectomy for stage T1q transitional cell carcinoma of the bladder
    • Ali-El-Dein B., Al-Marthoon M.S., Abdel Latif M., et al. Survival after primary and deferred cystectomy for stage T1q transitional cell carcinoma of the bladder. Urol Ann 2011, 3(3):127-132.
    • (2011) Urol Ann , vol.3 , Issue.3 , pp. 127-132
    • Ali-El-Dein, B.1    Al-Marthoon, M.S.2    Abdel Latif, M.3
  • 60
    • 0035254218 scopus 로고    scopus 로고
    • Radical cystectomy in treatment of invasive bladder cancer: long-term results in 1,054 patients
    • Stein J.P., Lieskovsky G., Cote R., et al. Radical cystectomy in treatment of invasive bladder cancer: long-term results in 1,054 patients. J Clin Oncol 2001, 19:666-675.
    • (2001) J Clin Oncol , vol.19 , pp. 666-675
    • Stein, J.P.1    Lieskovsky, G.2    Cote, R.3
  • 61
    • 77954676300 scopus 로고    scopus 로고
    • Adjuvant and neoadjuvant radiotherapy for bladder cancer: revisited
    • Zaghloul M.S. Adjuvant and neoadjuvant radiotherapy for bladder cancer: revisited. Future Oncol. 2010, 6(7):1177-1191.
    • (2010) Future Oncol. , vol.6 , Issue.7 , pp. 1177-1191
    • Zaghloul, M.S.1
  • 62
    • 0036555446 scopus 로고    scopus 로고
    • Disease specific survival as endpoint of outcome for bladder cancer patients following radical cystectomy
    • Gschwend J.E., Dahm P., Fair W.R. Disease specific survival as endpoint of outcome for bladder cancer patients following radical cystectomy. Eur Urol. 2002, 41(4):440-448.
    • (2002) Eur Urol. , vol.41 , Issue.4 , pp. 440-448
    • Gschwend, J.E.1    Dahm, P.2    Fair, W.R.3
  • 63
    • 1842863549 scopus 로고    scopus 로고
    • Et al.:Radical cystectomy for invasive bladdercancer, results of multi-institutional pooled analysis
    • Takahashi A., Tsukamoto T. Et al.:Radical cystectomy for invasive bladdercancer, results of multi-institutional pooled analysis. Jpn. J. Clin. Oncol. 2004, 34:14-19.
    • (2004) Jpn. J. Clin. Oncol. , vol.34 , pp. 14-19
    • Takahashi, A.1    Tsukamoto, T.2
  • 64
    • 33646358935 scopus 로고    scopus 로고
    • Clinical outcomes following radical cystectomy for primary nontransitional cell carcinoma for the bladder compared with transitional cell carcinoma of the bladder
    • Rogers C.G., Palapattu G.S., Shariat S.F., et al. Clinical outcomes following radical cystectomy for primary nontransitional cell carcinoma for the bladder compared with transitional cell carcinoma of the bladder. J Urol 2006, 175:2048-2053.
    • (2006) J Urol , vol.175 , pp. 2048-2053
    • Rogers, C.G.1    Palapattu, G.S.2    Shariat, S.F.3
  • 65
    • 63149121715 scopus 로고    scopus 로고
    • Urothelial carcinoma versus squamous cell carcinoma of bladder: is survival different with stage adjustment?
    • Scosyrev E., Yao J., Messing E. Urothelial carcinoma versus squamous cell carcinoma of bladder: is survival different with stage adjustment?. Urology 2009, 73:822-827.
    • (2009) Urology , vol.73 , pp. 822-827
    • Scosyrev, E.1    Yao, J.2    Messing, E.3
  • 66
    • 75849129336 scopus 로고    scopus 로고
    • Hulsbergen-van de Kaa CA et al.: Clinical epidemiology of nonurothelial bladder cancer: analysis of The Netherlands Cancer Registry
    • Ploeg M., Aben K.K. Hulsbergen-van de Kaa CA et al.: Clinical epidemiology of nonurothelial bladder cancer: analysis of The Netherlands Cancer Registry. J. Urol. 2010, 183(3):915-920.
    • (2010) J. Urol. , vol.183 , Issue.3 , pp. 915-920
    • Ploeg, M.1    Aben, K.K.2
  • 67
    • 0018704240 scopus 로고
    • El Bolkainy et al.: Preoperative irradiation of T3 carcinoma in Bilharzial bladder
    • Awwad H.K., Baki H.A. El Bolkainy et al.: Preoperative irradiation of T3 carcinoma in Bilharzial bladder. Int. J. Radiat. Oncol. Biol. Phys. 1979, 5:787-794.
    • (1979) Int. J. Radiat. Oncol. Biol. Phys. , vol.5 , pp. 787-794
    • Awwad, H.K.1    Baki, H.A.2
  • 68
    • 0021842649 scopus 로고
    • Randomized trial of cystectomy with or without preoperative radiotherapy for carcinoma of the bilharzial bladder
    • Ghoneim M.A., Ashamalla A.G., Awwad H.K., Whitmore W.F. Randomized trial of cystectomy with or without preoperative radiotherapy for carcinoma of the bilharzial bladder. J. Urol. 1985, 134:266-268.
    • (1985) J. Urol. , vol.134 , pp. 266-268
    • Ghoneim, M.A.1    Ashamalla, A.G.2    Awwad, H.K.3    Whitmore, W.F.4
  • 70
    • 0026666023 scopus 로고
    • Combined pre- and post-operative adjuvant radiation therapy for bladder cancer - a ten year experience
    • Reisinger S., Mohiuddin M., Mulholland S. Combined pre- and post-operative adjuvant radiation therapy for bladder cancer - a ten year experience. Int. J. Radiat. Oncol. Biol. Phys. 1992, 24:463-468.
    • (1992) Int. J. Radiat. Oncol. Biol. Phys. , vol.24 , pp. 463-468
    • Reisinger, S.1    Mohiuddin, M.2    Mulholland, S.3
  • 71
    • 25144524385 scopus 로고    scopus 로고
    • Reappraisal of the role of adjuvant radiotherapy in muscle-invasive transitional cell carcinoma of the bladder
    • Cozzarini C., Pelegrini D., Fallini M., et al. Reappraisal of the role of adjuvant radiotherapy in muscle-invasive transitional cell carcinoma of the bladder. Int. J. Radiat. Oncol. Biol. Phys. 1999, 45:221.
    • (1999) Int. J. Radiat. Oncol. Biol. Phys. , vol.45 , pp. 221
    • Cozzarini, C.1    Pelegrini, D.2    Fallini, M.3
  • 73
    • 30744455279 scopus 로고    scopus 로고
    • Long-term results of primary adenocarcinoma of the urinary bladder: a report on 192 patients
    • Zaghloul M.S., Nouh A., Nazmy M., et al. Long-term results of primary adenocarcinoma of the urinary bladder: a report on 192 patients. Urol Oncol 2006, 24:13-20.
    • (2006) Urol Oncol , vol.24 , pp. 13-20
    • Zaghloul, M.S.1    Nouh, A.2    Nazmy, M.3
  • 74
    • 84861757520 scopus 로고    scopus 로고
    • A prospective randomized trial for postoperative vs. preoperative adjuvant radiotherapy for muscle-invasive bladder cancer
    • Epub ahead of print
    • El-Moneim H.A., El-Baradie M.M., Younis A., Ragab Y., Labib A., El-Attar I. A prospective randomized trial for postoperative vs. preoperative adjuvant radiotherapy for muscle-invasive bladder cancer. Urol Oncol 2011, Epub ahead of print.
    • (2011) Urol Oncol
    • El-Moneim, H.A.1    El-Baradie, M.M.2    Younis, A.3    Ragab, Y.4    Labib, A.5    El-Attar, I.6
  • 75
    • 85011975132 scopus 로고    scopus 로고
    • Guirelines on bladder cancer muscle-invasive and metastatic
    • Stenzl A, Witjes A, Comperat E et al. Guirelines on bladder cancer muscle-invasive and metastatic. European Association of Urology 2012. www.uroweb.org/professional resourse/ guidelines accessed August 5,2012.
    • (2012) European Association of Urology 2012
    • Stenzl, A.1    Witjes, A.2    Comperat, E.3
  • 76
    • 77958030101 scopus 로고    scopus 로고
    • The need to revisit adjuvant and neoadjuvant radiotherapy in bladder cancer
    • Zaghloul M.S. The need to revisit adjuvant and neoadjuvant radiotherapy in bladder cancer. Exp Rev Anicancer Ther 2010, 10(10):1527-1528.
    • (2010) Exp Rev Anicancer Ther , vol.10 , Issue.10 , pp. 1527-1528
    • Zaghloul, M.S.1
  • 77
    • 18044372410 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy in patients with invasive bladder caner
    • Vaughn D.J., Malkowicz S.B. Neoadjuvant chemotherapy in patients with invasive bladder caner. Urol Clin North Am. 2005, 32:231-237.
    • (2005) Urol Clin North Am. , vol.32 , pp. 231-237
    • Vaughn, D.J.1    Malkowicz, S.B.2
  • 78
    • 0347759903 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy for transitional cell carcinoma of the bladder: a systematic review and meta-analysis
    • Winquist E., Kichner T.S., Segal R., et al. Neoadjuvant chemotherapy for transitional cell carcinoma of the bladder: a systematic review and meta-analysis. J Urol 2004, 171:561-569.
    • (2004) J Urol , vol.171 , pp. 561-569
    • Winquist, E.1    Kichner, T.S.2    Segal, R.3
  • 79
    • 84862853718 scopus 로고    scopus 로고
    • Advanced Bladder Cancer Meta-analysis Collaboration. Adjuvant chemotherapy for invasive bladder cancer
    • CD006018
    • Vale C.L. Advanced Bladder Cancer Meta-analysis Collaboration. Adjuvant chemotherapy for invasive bladder cancer. Cochrane Database Syst Rev 2006, CD006018.
    • (2006) Cochrane Database Syst Rev
    • Vale, C.L.1
  • 80
    • 32544457106 scopus 로고    scopus 로고
    • Adjuvant chemotherapy in muscle-invasive bladder cancer: a pooled analysis from phase III studies
    • Ruggeri E.M., Giannarelli D., Bria E., et al. Adjuvant chemotherapy in muscle-invasive bladder cancer: a pooled analysis from phase III studies. Cancer 2006, 106:783-788.
    • (2006) Cancer , vol.106 , pp. 783-788
    • Ruggeri, E.M.1    Giannarelli, D.2    Bria, E.3
  • 81
    • 32644487649 scopus 로고    scopus 로고
    • Gemcitabine and cisplatin as neoadjuvant chemotherapy for invasive bladder cancer: Effect on bladder preservation and survival
    • abstr 1652
    • Khaled H., Zaghloul M., Ghoneim M., et al. Gemcitabine and cisplatin as neoadjuvant chemotherapy for invasive bladder cancer: Effect on bladder preservation and survival. Proc Am Soc Clin Oncol 2003, 22:411. abstr 1652.
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 411
    • Khaled, H.1    Zaghloul, M.2    Ghoneim, M.3
  • 82
    • 11144291099 scopus 로고    scopus 로고
    • Current status of radiation therapy and combined-modality treatment for bladder cancer
    • Rödel C. Current status of radiation therapy and combined-modality treatment for bladder cancer. Strahlenther Onkol. 2004, 180(11):701-709.
    • (2004) Strahlenther Onkol. , vol.180 , Issue.11 , pp. 701-709
    • Rödel, C.1
  • 83
    • 78649638729 scopus 로고    scopus 로고
    • Trimodality treatment for bladder cancer: does modern radiotherapy improve the end results?
    • Zaghloul M.S., Mousa A.G. Trimodality treatment for bladder cancer: does modern radiotherapy improve the end results?. Expert Rev Anticancer Ther. 2010, 10(12):1933-1944.
    • (2010) Expert Rev Anticancer Ther. , vol.10 , Issue.12 , pp. 1933-1944
    • Zaghloul, M.S.1    Mousa, A.G.2
  • 84
    • 0031059139 scopus 로고    scopus 로고
    • Bladder preservation by combined modality therapy for invasive bladder cancer
    • Kachnic L.A., Kaufman D.S., Heney N.M., et al. Bladder preservation by combined modality therapy for invasive bladder cancer. J Clin Oncol. 1997, 15(3):1022-1029.
    • (1997) J Clin Oncol. , vol.15 , Issue.3 , pp. 1022-1029
    • Kachnic, L.A.1    Kaufman, D.S.2    Heney, N.M.3
  • 85
    • 0031763392 scopus 로고    scopus 로고
    • Phase III trial of neoadjuvant chemotherapy in patients with invasive bladder cancer treated with selective bladder preservation by combined radiation therapy and chemotherapy: initial results of Radiation Therapy Oncology Group 89-03
    • Shipley W.U., Winter K.A., Kaufman D.S., et al. Phase III trial of neoadjuvant chemotherapy in patients with invasive bladder cancer treated with selective bladder preservation by combined radiation therapy and chemotherapy: initial results of Radiation Therapy Oncology Group 89-03. J Clin Oncol. 1998, 16(11):3576-3583.
    • (1998) J Clin Oncol. , vol.16 , Issue.11 , pp. 3576-3583
    • Shipley, W.U.1    Winter, K.A.2    Kaufman, D.S.3
  • 86
    • 0343618439 scopus 로고    scopus 로고
    • Chemoradiotherapy for muscle invading bladder carcinoma. Final report of a single institutional organ-sparing program
    • Arias F., Domínguez M.A., Martínez E., et al. Chemoradiotherapy for muscle invading bladder carcinoma. Final report of a single institutional organ-sparing program. Int J Radiat Oncol Biol Phys. 2000, 47(2):373-378.
    • (2000) Int J Radiat Oncol Biol Phys. , vol.47 , Issue.2 , pp. 373-378
    • Arias, F.1    Domínguez, M.A.2    Martínez, E.3
  • 87
    • 0027221462 scopus 로고
    • Combined modality program with possible organ preservation for invasive bladder carcinoma: results of RTOG protocol 85-12
    • Tester W., Porter A., Asbell S., et al. Combined modality program with possible organ preservation for invasive bladder carcinoma: results of RTOG protocol 85-12. Int. J. Radiat. Oncol. Biol. Phys. 1993, 25(5):783-790.
    • (1993) Int. J. Radiat. Oncol. Biol. Phys. , vol.25 , Issue.5 , pp. 783-790
    • Tester, W.1    Porter, A.2    Asbell, S.3
  • 88
    • 0031985484 scopus 로고    scopus 로고
    • Efficacy of radiochemotherapy with platin derivatives compared to radiotherapy alone in organ-sparing treatment of bladder cancer
    • Sauer R., Birkenhake S., Kühn R., Wittekind C., Schrott K.M., Martus P. Efficacy of radiochemotherapy with platin derivatives compared to radiotherapy alone in organ-sparing treatment of bladder cancer. Int J Radiat Oncol Biol Phys. 1998, 40(1):121-127.
    • (1998) Int J Radiat Oncol Biol Phys. , vol.40 , Issue.1 , pp. 121-127
    • Sauer, R.1    Birkenhake, S.2    Kühn, R.3    Wittekind, C.4    Schrott, K.M.5    Martus, P.6
  • 89
    • 72549106330 scopus 로고    scopus 로고
    • Combined modality treatment with bladder preservation for muscle invasive bladder cancer
    • Sabaa M.A., El-Gamal O.M., Abo-Elenen M., Khanam A. Combined modality treatment with bladder preservation for muscle invasive bladder cancer. Urol. Oncol. 2010, 28:14-20.
    • (2010) Urol. Oncol. , vol.28 , pp. 14-20
    • Sabaa, M.A.1    El-Gamal, O.M.2    Abo-Elenen, M.3    Khanam, A.4
  • 90
    • 79952279140 scopus 로고    scopus 로고
    • Initial results of bladder preserving approach by chemoradiotherapy in patients with muscle invading transitional cell carcinoma
    • Aboziada M., Hamza H.M., Abdelrahman A.M. Initial results of bladder preserving approach by chemoradiotherapy in patients with muscle invading transitional cell carcinoma. J Egypt Nat Cancer Inst 2009, 21(2):167-174.
    • (2009) J Egypt Nat Cancer Inst , vol.21 , Issue.2 , pp. 167-174
    • Aboziada, M.1    Hamza, H.M.2    Abdelrahman, A.M.3
  • 91
    • 33750885453 scopus 로고    scopus 로고
    • Outcomes in patients with urothelial carcinoma of the bladder with limited pelvic lymph node dissection
    • Dhar N.B., Campbell S.C., Zippe C.D., et al. Outcomes in patients with urothelial carcinoma of the bladder with limited pelvic lymph node dissection. BJU Int. 2006, 98(6):1172-1175.
    • (2006) BJU Int. , vol.98 , Issue.6 , pp. 1172-1175
    • Dhar, N.B.1    Campbell, S.C.2    Zippe, C.D.3
  • 92
    • 70349977006 scopus 로고    scopus 로고
    • Radical cystectomy for urothelial carcinoma of the bladder: an analysis of perioperative and survival outcome
    • Manoharan M., Ayyathurai R., Soloway M.S. Radical cystectomy for urothelial carcinoma of the bladder: an analysis of perioperative and survival outcome. BJU Int. 2009, 104(9):1227-1232.
    • (2009) BJU Int. , vol.104 , Issue.9 , pp. 1227-1232
    • Manoharan, M.1    Ayyathurai, R.2    Soloway, M.S.3
  • 93
    • 84857033061 scopus 로고    scopus 로고
    • Survival after radical cystectomy of non-bilharzial squamous cell carcinoma vs urothelial carcinoma: a competing-risks analysis
    • Abdollah F., Sun M., Jeldres C., et al. Survival after radical cystectomy of non-bilharzial squamous cell carcinoma vs urothelial carcinoma: a competing-risks analysis. BJU Int. 2012, 109(4):564-569.
    • (2012) BJU Int. , vol.109 , Issue.4 , pp. 564-569
    • Abdollah, F.1    Sun, M.2    Jeldres, C.3
  • 94
    • 78650701254 scopus 로고    scopus 로고
    • A population-based competing-risk analysis of the survival of patients treated with radical cystectomy for bladder cancer
    • Lughezzani G., Sun M., Shariat S.F., et al. A population-based competing-risk analysis of the survival of patients treated with radical cystectomy for bladder cancer. Cancer 2011, 117(1):103-109.
    • (2011) Cancer , vol.117 , Issue.1 , pp. 103-109
    • Lughezzani, G.1    Sun, M.2    Shariat, S.F.3
  • 95
    • 9144260514 scopus 로고    scopus 로고
    • Clinical outcome of a large-scale multiinstitutional retrospective study for locally advanced bladder cancer: a survey including 1131 patients treated during 1990-2000 in Japan
    • Nishiyama H., Habuchi T., Watanabe J., et al. Clinical outcome of a large-scale multiinstitutional retrospective study for locally advanced bladder cancer: a survey including 1131 patients treated during 1990-2000 in Japan. Eur Urol 2004, 45:176-181.
    • (2004) Eur Urol , vol.45 , pp. 176-181
    • Nishiyama, H.1    Habuchi, T.2    Watanabe, J.3
  • 96
    • 46749119440 scopus 로고    scopus 로고
    • Outcomes for a large series of radical cystectomies for bladder cancer
    • Niu H.T., Xu T., Zhang Y.B., et al. Outcomes for a large series of radical cystectomies for bladder cancer. Eur. J. Surg. Oncol. 2008, 34(8):911-915.
    • (2008) Eur. J. Surg. Oncol. , vol.34 , Issue.8 , pp. 911-915
    • Niu, H.T.1    Xu, T.2    Zhang, Y.B.3
  • 97
    • 0031852372 scopus 로고    scopus 로고
    • El-Baz MA, Abol-Enein H, Ghoneim MA. Primary adenocarcinoma of the urinary bladder: a report of 185 cases
    • El-Mekresh M.M. El-Baz MA, Abol-Enein H, Ghoneim MA. Primary adenocarcinoma of the urinary bladder: a report of 185 cases. Br J Urol 1998, 82(2):206-212.
    • (1998) Br J Urol , vol.82 , Issue.2 , pp. 206-212
    • El-Mekresh, M.M.1
  • 98
    • 21844432908 scopus 로고    scopus 로고
    • A prognostic index (bladder prognostic index) for bilharzial-related invasive bladder cancer
    • Khaled H., El-Hattab O., Moneim D.A., Kassem H.A., Morsi A., Sherif G. A prognostic index (bladder prognostic index) for bilharzial-related invasive bladder cancer. Urol. Oncol. 2005, 23:254-260.
    • (2005) Urol. Oncol. , vol.23 , pp. 254-260
    • Khaled, H.1    El-Hattab, O.2    Moneim, D.A.3    Kassem, H.A.4    Morsi, A.5    Sherif, G.6
  • 99
    • 76549131083 scopus 로고    scopus 로고
    • El Baradie Nouh MA, Abdel-Fatah S, Taher A and Shalaan M. Prognostic index for primary adenocarcinoma of the urinary bladder. Gulf J
    • Zaghloul M.S. El Baradie Nouh MA, Abdel-Fatah S, Taher A and Shalaan M. Prognostic index for primary adenocarcinoma of the urinary bladder. Gulf J. Oncol 2007, 1(2):47-54.
    • (2007) Oncol , vol.1 , Issue.2 , pp. 47-54
    • Zaghloul, M.S.1
  • 100
    • 0037441652 scopus 로고    scopus 로고
    • Radical cystectomy for bladder cancertoday: a homogeneous series without neoadjuvant therapy
    • Madersbacher S., Hochreiter W., Burkhard F., et al. Radical cystectomy for bladder cancertoday: a homogeneous series without neoadjuvant therapy. J Clin Oncol 2003, 21:690-696.
    • (2003) J Clin Oncol , vol.21 , pp. 690-696
    • Madersbacher, S.1    Hochreiter, W.2    Burkhard, F.3
  • 101
    • 71649087105 scopus 로고    scopus 로고
    • Radical cystectomy in the treatment of bladder cancer: oncological outcome and survival predictors
    • Ho C.H., Huang C.Y., Lin W.C., et al. Radical cystectomy in the treatment of bladder cancer: oncological outcome and survival predictors. J. Formos. Med. Assoc. 2009, 108(11):872-878.
    • (2009) J. Formos. Med. Assoc. , vol.108 , Issue.11 , pp. 872-878
    • Ho, C.H.1    Huang, C.Y.2    Lin, W.C.3


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