IP3 Receptor Type 2 Deficiency Is Associated with a Secretory Defect in the Pancreatic Acinar Cell and an Accumulation of Zymogen Granules

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Orabi, Abrahim I ^a   Luo, Yuhuan ^a   Ahmad, Mahwish U ^a   Shah, Ahsan U ^a   Mannan, Zahir ^a   Wang, Dong ^a   Sarwar, Sheharyar ^a   Muili, Kamaldeen A ^a   Shugrue, Christine ^b   Kolodecik, Thomas R ^b   Singh, Vijay P ^a   Lowe, Mark E ^a   Thrower, Edwin ^b   Chen, Ju ^c   Husain, Sohail Z ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLASE; CARBACHOL; CERULETIDE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR TYPE 2; TRYPSINOGEN; UNCLASSIFIED DRUG; ZYMOGEN GRANULE;

ACINAR CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELLULAR DISTRIBUTION; CHANNEL GATING; CONTROLLED STUDY; ENZYME RELEASE; MALE; MOLECULAR IMAGING; MOUSE; NONHUMAN; PANCREAS INJURY; PROTEIN DEFICIENCY; PROTEIN LOCALIZATION; WILD TYPE;

ACINAR CELLS; AMYLASES; ANIMALS; CAERULEIN; CALCIUM SIGNALING; CELL POLARITY; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; MALE; MICE; PANCREAS; SECRETORY VESICLES;

MUS;

EID: 84869761557     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048465     Document Type: Article

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