IPP5, a novel inhibitor of protein phosphatase 1, suppresses tumor growth and progression of cervical carcinoma cells by inducing G2/M arrest

Cancer Genetics

Volumn 205, Issue 9, 2012, Pages 442-452

  Zeng, Qiyan ^a   Huang, Yu ^b   Zeng, Linjie ^c   Huang, Yongqi ^a   Cai, Danzhao ^a   Zhang, Hong ^a  

^a GUANGXI MEDICAL UNIVERSITY   (China)

^b FIRST MILITARY MEDICAL UNIVERSITY   (China)

^c Orthopaedics Hospital   (China)

Author keywords

G2 M arrest; Growth suppression; HeLa cells; IPP5; Signal transduction

Indexed keywords

CYCLIN A1; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; PROTEIN P21; PROTEIN P53; PROTEIN PHOSPHATASE 1 INHIBITOR 5; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GENE THERAPY; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CONTROLLED STUDY; CYTOKINESIS; DRUG MECHANISM; ENZYME ACTIVATION; FEMALE; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; UTERINE CERVIX CARCINOMA;

ANIMALS; BONE MARROW CELLS; CELL GROWTH PROCESSES; CELL MOVEMENT; CYCLINS; CYTOKINESIS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; G2 PHASE CELL CYCLE CHECKPOINTS; GENETIC THERAPY; HELA CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; M PHASE CELL CYCLE CHECKPOINTS; MAP KINASE SIGNALING SYSTEM; MICE; MICE, NUDE; PROTEINS; TRANSFECTION; UTERINE CERVICAL NEOPLASMS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84869753885     PISSN: 22107762     EISSN: 22107770     Source Type: Journal    
DOI: 10.1016/j.cancergen.2012.06.002     Document Type: Article

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