Ezetimibe inhibits PMA-induced monocyte/macrophage differentiation by altering microRNA expression: A novel anti-atherosclerotic mechanism

Pharmacological Research

Volumn 66, Issue 6, 2012, Pages 536-543

  Muñoz Pacheco, Paloma ^a   Ortega Hernández, Adriana ^a   Miana, María ^b   Cachofeiro, Victoria ^b   Fernández Cruz, Arturo ^c   Gómez Garre, Dulcenombre ^a  

^a HOSPITAL CLÍNICO SAN CARLOS   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c INSTITUTO DE INVESTIGACIÓN SANITARIA DEL HOSPITAL CLÍNICO SAN CARLOS IDISSC   (Spain)

Author keywords

Differentiation; Ezetimibe; MicroRNAs; Monocyte macrophage

Indexed keywords

CD11B ANTIGEN; EZETIMIBE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MICRORNA; MICRORNA 155; MICRORNA 222; MICRORNA 424; MICRORNA 503; MITOGEN ACTIVATED PROTEIN KINASE; PHORBOL 13 ACETATE 12 MYRISTATE; UNCLASSIFIED DRUG;

ANTIATHEROSCLEROTIC MECHANISM; ARTICLE; CELL ADHESION; CELL DIFFERENTIATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SURFACE PROPERTY;

ANTICHOLESTEREMIC AGENTS; ATHEROSCLEROSIS; AZETIDINES; CELL ADHESION; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL LINE; FLOW CYTOMETRY; HUMANS; MACROPHAGES; MICRORNAS; MONOCYTES; NF-KAPPA B; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; TETRADECANOYLPHORBOL ACETATE;

EID: 84869506166     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2012.09.005     Document Type: Article

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