메뉴 건너뛰기




Volumn 43, Issue 12, 2012, Pages 2167-2176

Multiplex high-throughput gene mutation analysis in acute myeloid leukemia

Author keywords

Acute myeloid leukemia; Gene mutation; Genetics; Molecular

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AGED; ARTICLE; CEBPA GENE; CHROMOSOME ABERRATION; CYTOGENETICS; DNA SEQUENCE; FEMALE; FLT3 GENE; FLT3 ITD GENE; GENE MUTATION; GENOTYPE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN TISSUE; IDH1 GENE; KARYOTYPE; KIT GENE; MAJOR CLINICAL STUDY; MALE; MULTIPLEX POLYMERASE CHAIN REACTION; MUTATIONAL ANALYSIS; NPM1 GENE; ONCOGENE; ONCOGENE K RAS; ONCOGENE N RAS; POINT MUTATION; PTPN11 GENE;

EID: 84869497111     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2012.03.002     Document Type: Article
Times cited : (16)

References (24)
  • 2
    • 77958531206 scopus 로고    scopus 로고
    • Acute myeloid leukemia diagnosis in the 21st century
    • B.L. Betz, and J.L. Hess Acute myeloid leukemia diagnosis in the 21st century Arch Pathol Lab Med 134 2010 1427 1433
    • (2010) Arch Pathol Lab Med , vol.134 , pp. 1427-1433
    • Betz, B.L.1    Hess, J.L.2
  • 3
    • 41949090673 scopus 로고    scopus 로고
    • The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia
    • R.E. Gale, C. Green, and C. Allen The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia Blood 111 2008 2776 2784
    • (2008) Blood , vol.111 , pp. 2776-2784
    • Gale, R.E.1    Green, C.2    Allen, C.3
  • 4
    • 42949142189 scopus 로고    scopus 로고
    • Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia
    • R.F. Schlenk, K. Dohner, and J. Krauter Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia N Engl J Med 358 2008 1909 1918
    • (2008) N Engl J Med , vol.358 , pp. 1909-1918
    • Schlenk, R.F.1    Dohner, K.2    Krauter, J.3
  • 5
    • 67650924270 scopus 로고    scopus 로고
    • Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML
    • A. Tefferi, K.H. Lim, and O. Abdel-Wahab Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML Leukemia 23 2009 1343 1345
    • (2009) Leukemia , vol.23 , pp. 1343-1345
    • Tefferi, A.1    Lim, K.H.2    Abdel-Wahab, O.3
  • 6
    • 78649906060 scopus 로고    scopus 로고
    • DNMT3A mutations in acute myeloid leukemia
    • T.J. Ley, L. Ding, and M.J. Walter DNMT3A mutations in acute myeloid leukemia N Engl J Med 363 2010 2424 2433
    • (2010) N Engl J Med , vol.363 , pp. 2424-2433
    • Ley, T.J.1    Ding, L.2    Walter, M.J.3
  • 7
    • 70149093912 scopus 로고    scopus 로고
    • Recurring mutations found by sequencing an acute myeloid leukemia genome
    • E.R. Mardis, L. Ding, and D.J. Dooling Recurring mutations found by sequencing an acute myeloid leukemia genome N Engl J Med 361 2009 1058 1066
    • (2009) N Engl J Med , vol.361 , pp. 1058-1066
    • Mardis, E.R.1    Ding, L.2    Dooling, D.J.3
  • 8
    • 79952092487 scopus 로고    scopus 로고
    • Molecular genetics of adult acute myeloid leukemia: Prognostic and therapeutic implications
    • G. Marcucci, T. Haferlach, and H. Dohner Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications J Clin Oncol 29 2011 475 486
    • (2011) J Clin Oncol , vol.29 , pp. 475-486
    • Marcucci, G.1    Haferlach, T.2    Dohner, H.3
  • 9
    • 77449159028 scopus 로고    scopus 로고
    • Diagnosis and management of acute myeloid leukemia in adults: Recommendations from an international expert panel, on behalf of the European LeukemiaNet
    • H. Dohner, E.H. Estey, and S. Amadori Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet Blood 115 2010 453 474
    • (2010) Blood , vol.115 , pp. 453-474
    • Dohner, H.1    Estey, E.H.2    Amadori, S.3
  • 10
    • 82655176916 scopus 로고    scopus 로고
    • Multiplex mutation screening by mass spectrometry evaluation of 820 cases from a personalized cancer medicine registry
    • C. Beadling, M.C. Heinrich, and A. Warrick Multiplex mutation screening by mass spectrometry evaluation of 820 cases from a personalized cancer medicine registry J Mol Diagn 13 2011 504 513
    • (2011) J Mol Diagn , vol.13 , pp. 504-513
    • Beadling, C.1    Heinrich, M.C.2    Warrick, A.3
  • 11
    • 64949122396 scopus 로고    scopus 로고
    • Heterogeneity within AML with CEBPA mutations; Only CEBPA double mutations, but not single CEBPA mutations are associated with favourable prognosis
    • T. Pabst, M. Eyholzer, and J. Fos Heterogeneity within AML with CEBPA mutations; only CEBPA double mutations, but not single CEBPA mutations are associated with favourable prognosis Br J Cancer 100 2009 1343 1346
    • (2009) Br J Cancer , vol.100 , pp. 1343-1346
    • Pabst, T.1    Eyholzer, M.2    Fos, J.3
  • 12
    • 70849116358 scopus 로고    scopus 로고
    • Profiling critical cancer gene mutations in clinical tumor samples
    • L.E. MacConaill, C.D. Campbell, and S.M. Kehoe Profiling critical cancer gene mutations in clinical tumor samples PLoS One 4 2009 e7887
    • (2009) PLoS One , vol.4 , pp. 7887
    • MacConaill, L.E.1    Campbell, C.D.2    Kehoe, S.M.3
  • 13
    • 33847293670 scopus 로고    scopus 로고
    • High-throughput oncogene mutation profiling in human cancer
    • R.K. Thomas, A.C. Baker, and R.M. Debiasi High-throughput oncogene mutation profiling in human cancer Nat Genet 39 2007 347 351
    • (2007) Nat Genet , vol.39 , pp. 347-351
    • Thomas, R.K.1    Baker, A.C.2    Debiasi, R.M.3
  • 14
    • 77952424259 scopus 로고    scopus 로고
    • Molecular alterations of the IDH1 gene in AML: A Children's Oncology Group and Southwest Oncology Group study
    • P.A. Ho, T.A. Alonzo, and K.J. Kopecky Molecular alterations of the IDH1 gene in AML: a Children's Oncology Group and Southwest Oncology Group study Leukemia 24 2010 909 913
    • (2010) Leukemia , vol.24 , pp. 909-913
    • Ho, P.A.1    Alonzo, T.A.2    Kopecky, K.J.3
  • 15
    • 79251510890 scopus 로고    scopus 로고
    • Acute myeloid leukemia with IDH1 or IDH2 mutation: Frequency and clinicopathologic features
    • K.P. Patel, F. Ravandi, and D. Ma Acute myeloid leukemia with IDH1 or IDH2 mutation: frequency and clinicopathologic features Am J Clin Pathol 135 2011 35 45
    • (2011) Am J Clin Pathol , vol.135 , pp. 35-45
    • Patel, K.P.1    Ravandi, F.2    Ma, D.3
  • 16
    • 77957771067 scopus 로고    scopus 로고
    • IDH1 mutations are detected in 6.6% of 1414 AML patients and are associated with intermediate risk karyotype and unfavorable prognosis in adults younger than 60 years and unmutated NPM1 status
    • S. Schnittger, C. Haferlach, and M. Ulke IDH1 mutations are detected in 6.6% of 1414 AML patients and are associated with intermediate risk karyotype and unfavorable prognosis in adults younger than 60 years and unmutated NPM1 status Blood 116 2010 5486 5496
    • (2010) Blood , vol.116 , pp. 5486-5496
    • Schnittger, S.1    Haferlach, C.2    Ulke, M.3
  • 17
    • 77955907891 scopus 로고    scopus 로고
    • IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication
    • P. Paschka, R.F. Schlenk, and V.I. Gaidzik IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication J Clin Oncol 28 2010 3636 3643
    • (2010) J Clin Oncol , vol.28 , pp. 3636-3643
    • Paschka, P.1    Schlenk, R.F.2    Gaidzik, V.I.3
  • 18
    • 79955973367 scopus 로고    scopus 로고
    • Integrative prognostic risk score in acute myeloid leukemia with normal karyotype
    • F. Damm, M. Heuser, and M. Morgan Integrative prognostic risk score in acute myeloid leukemia with normal karyotype Blood 117 2011 4561 4568
    • (2011) Blood , vol.117 , pp. 4561-4568
    • Damm, F.1    Heuser, M.2    Morgan, M.3
  • 19
    • 79960973763 scopus 로고    scopus 로고
    • Risk stratification of intermediate-risk acute myeloid leukemia: Integrative analysis of a multitude of gene mutation and gene expression markers
    • V. Rockova, S. Abbas, and B.J. Wouters Risk stratification of intermediate-risk acute myeloid leukemia: integrative analysis of a multitude of gene mutation and gene expression markers Blood 118 2011 1069 1076
    • (2011) Blood , vol.118 , pp. 1069-1076
    • Rockova, V.1    Abbas, S.2    Wouters, B.J.3
  • 20
    • 81555228423 scopus 로고    scopus 로고
    • Gene mutation patterns and their prognostic impact in a cohort of 1185 patients with acute myeloid leukemia
    • Y. Shen, Y.M. Zhu, and X. Fan Gene mutation patterns and their prognostic impact in a cohort of 1185 patients with acute myeloid leukemia Blood 118 2011 5593 5603
    • (2011) Blood , vol.118 , pp. 5593-5603
    • Shen, Y.1    Zhu, Y.M.2    Fan, X.3
  • 21
    • 1542503817 scopus 로고    scopus 로고
    • Acquisition of FLT3 or N-ras mutations is frequently associated with progression of myelodysplastic syndrome to acute myeloid leukemia
    • L.Y. Shih, C.F. Huang, and P.N. Wang Acquisition of FLT3 or N-ras mutations is frequently associated with progression of myelodysplastic syndrome to acute myeloid leukemia Leukemia 18 2004 466 475
    • (2004) Leukemia , vol.18 , pp. 466-475
    • Shih, L.Y.1    Huang, C.F.2    Wang, P.N.3
  • 22
    • 33646575624 scopus 로고    scopus 로고
    • Implications of NRAS mutations in AML: A study of 2502 patients
    • U. Bacher, T. Haferlach, and C. Schoch Implications of NRAS mutations in AML: a study of 2502 patients Blood 107 2006 3847 3853
    • (2006) Blood , vol.107 , pp. 3847-3853
    • Bacher, U.1    Haferlach, T.2    Schoch, C.3
  • 23
    • 24744449132 scopus 로고    scopus 로고
    • RAS mutation in acute myeloid leukemia is associated with distinct cytogenetic subgroups but does not influence outcome in patients younger than 60 years
    • D.T. Bowen, M.E. Frew, and R. Hills RAS mutation in acute myeloid leukemia is associated with distinct cytogenetic subgroups but does not influence outcome in patients younger than 60 years Blood 106 2005 2113 2119
    • (2005) Blood , vol.106 , pp. 2113-2119
    • Bowen, D.T.1    Frew, M.E.2    Hills, R.3
  • 24
    • 79952182407 scopus 로고    scopus 로고
    • High-throughput mutation profiling of CTCL samples reveals KRAS and NRAS mutations sensitizing tumors toward inhibition of the RAS/RAF/MEK signaling cascade
    • M.K. Kiessling, P.A. Oberholzer, and C. Mondal High-throughput mutation profiling of CTCL samples reveals KRAS and NRAS mutations sensitizing tumors toward inhibition of the RAS/RAF/MEK signaling cascade Blood 117 2011 2433 2440
    • (2011) Blood , vol.117 , pp. 2433-2440
    • Kiessling, M.K.1    Oberholzer, P.A.2    Mondal, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.