메뉴 건너뛰기




Volumn 120, Issue 3, 2012, Pages 241-249

Fasudil suppresses fibrosarcoma growth by stimulating secretion of the chemokine CXCL14/BRAK

Author keywords

5 (1,4 Diazepane 1 sulfonyl) isoquinoline; CXCL14 BRAK; Fasudil; Fibrosarcoma cell; Ras homologous small GTPase

Indexed keywords

CXCL14 CHEMOKINE; FASUDIL; MESSENGER RNA; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 84869469250     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.12177FP     Document Type: Article
Times cited : (14)

References (47)
  • 3
    • 17844381906 scopus 로고    scopus 로고
    • Loss of new chemokine CXCL14 in tumor tissue is associated with low infiltration by Dendritic Cells (DC), while restoration of human CXCL14 expression in tumor cells causes attraction of DC both in vitro and in vivo
    • Shurin GV, Ferris RL, Tourkova IL, Perez L, Lokshin A, Balkir L, et al. Loss of new chemokine CXCL14 in tumor tissue is associated with low infiltration by dendritic cells (DC), while restoration of human CXCL14 expression in tumor cells causes attraction of DC both in vitro and in vivo. J Immunol. 2005;174:5490-5498. (Pubitemid 40593189)
    • (2005) Journal of Immunology , vol.174 , Issue.9 , pp. 5490-5498
    • Shurin, G.V.1    Ferris, R.2    Tourkova, I.L.3    Perez, L.4    Lokshin, A.5    Balkir, L.6    Collins, B.7    Chatta, G.S.8    Shurin, M.R.9
  • 4
    • 78149471244 scopus 로고    scopus 로고
    • Chemokine CXCL14/BRAK transgenic mice suppress growth of carcinoma cell transplants.
    • corrected
    • Izukuri K, Suzuki K, Yajima N, Ozawa S, Ito S, Kubota E, et al. Chemokine CXCL14/BRAK transgenic mice suppress growth of carcinoma cell transplants. [corrected]. Transgenic Res. 2010;19:1109-1117.
    • (2010) Transgenic Res , vol.19 , pp. 1109-1117
    • Izukuri, K.1    Suzuki, K.2    Yajima, N.3    Ozawa, S.4    Ito, S.5    Kubota, E.6
  • 6
    • 33746095784 scopus 로고    scopus 로고
    • The chemokine CXCL14 (BRAK) stimulates activated NK cell migration: Implications for the downregulation of CXCL14 in malignancy
    • DOI 10.1016/j.exphem.2006.05.015, PII S0301472X06003328
    • Starnes T, Rasila KK, Robertson MJ, Brahmi Z, Dahl R, Christopherson K, et al. The chemokine CXCL14 (BRAK) stimulates activated NK cell migration: implications for the downregulation of CXCL14 in malignancy. Exp Hematol. 2006;34:1101-1105. (Pubitemid 44080391)
    • (2006) Experimental Hematology , vol.34 , Issue.8 , pp. 1101-1105
    • Starnes, T.1    Rasila, K.K.2    Robertson, M.J.3    Brahmi, Z.4    Dahl, R.5    Christopherson, K.6    Hromas, R.7
  • 7
    • 77956929100 scopus 로고    scopus 로고
    • Re-expression of CXCL14, a common target for epigenetic silencing in lung cancer, induces tumor necrosis
    • Tessema M, Klinge DM, Yingling CM, Do K, Van Neste L, Belinsky SA. Re-expression of CXCL14, a common target for epigenetic silencing in lung cancer, induces tumor necrosis. Oncogene. 2010;29:5159-5170.
    • (2010) Oncogene. , vol.29 , pp. 5159-5170
    • Tessema, M.1    Klinge, D.M.2    Yingling, C.M.3    Do, K.4    Van Neste, L.5    Belinsky, S.A.6
  • 9
    • 70350761864 scopus 로고    scopus 로고
    • BRAK/CXCL14 expression in oral carcinoma cells completely suppresses tumor cell xenografts in SCID mouse
    • Ozawa S, Kato Y, Kubota E, Hata R. BRAK/CXCL14 expression in oral carcinoma cells completely suppresses tumor cell xenografts in SCID mouse. Biomed Res. 2009;30:315-318.
    • (2009) Biomed Res. , vol.30 , pp. 315-318
    • Ozawa, S.1    Kato, Y.2    Kubota, E.3    Hata, R.4
  • 10
    • 77953286924 scopus 로고    scopus 로고
    • Human p38 delta MAP kinase mediates UV irradiation induced up-regulation of the gene expression of chemokine BRAK/CXCL14
    • Ozawa S, Ito S, Kato Y, Kubota E, Hata R. Human p38 delta MAP kinase mediates UV irradiation induced up-regulation of the gene expression of chemokine BRAK/CXCL14. Biochem Biophys Res Commun. 2010;396:1060-1064.
    • (2010) Biochem Biophys Res Commun , vol.396 , pp. 1060-1064
    • Ozawa, S.1    Ito, S.2    Kato, Y.3    Kubota, E.4    Hata, R.5
  • 11
    • 77956377651 scopus 로고    scopus 로고
    • Reactive oxygen species (ROS) reduce the expression of BRAK/CXCL14 in human head and neck squamous cell carcinoma cells
    • Maehata Y, Ozawa S, Kobayashi K, Kato Y, Yoshino F, Miyamoto C, et al. Reactive oxygen species (ROS) reduce the expression of BRAK/CXCL14 in human head and neck squamous cell carcinoma cells. Free Radic Res. 2010;44:913-924.
    • (2010) Free Radic Res. , vol.44 , pp. 913-924
    • Maehata, Y.1    Ozawa, S.2    Kobayashi, K.3    Kato, Y.4    Yoshino, F.5    Miyamoto, C.6
  • 12
    • 0043160105 scopus 로고    scopus 로고
    • Overexpression of ROCK in human breast cancer cells: Evidence that ROCK activity mediates intracellular membrane traffic of lysosomes
    • Nishimura Y, Itoh K, Yoshioka K, Tokuda K, Himeno M. Overexpression of ROCK in human breast cancer cells: evidence that ROCK activity mediates intracellular membrane traffic of lysosomes. Pathol Oncol Res. 2003;9:83-95. (Pubitemid 36958628)
    • (2003) Pathology Oncology Research , vol.9 , Issue.2 , pp. 83-95
    • Nishimura, Y.1    Itoh, K.2    Yoshioka, K.3    Tokuda, K.4    Himeno, M.5
  • 13
    • 0028863142 scopus 로고
    • A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes
    • Leung T, Manser E, Tan L, Lim L. A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes. J Biol Chem. 1995;270:29051-29054.
    • (1995) J Biol Chem , vol.270 , pp. 29051-29054
    • Leung, T.1    Manser, E.2    Tan, L.3    Lim, L.4
  • 14
    • 0032935495 scopus 로고    scopus 로고
    • An essential part for Rho-associated kinase in the transcellular invasion of tumor cells
    • DOI 10.1038/5587
    • Itoh K, Yoshioka K, Akedo H, Uehata M, Ishizaki T, Narumiya S. An essential part for Rho-associated kinase in the transcellular invasion of tumor cells. Nat Med. 1999;5:221-225. (Pubitemid 29068531)
    • (1999) Nature Medicine , vol.5 , Issue.2 , pp. 221-225
    • Itoh, K.1    Yoshioka, K.2    Akedo, H.3    Uehata, M.4    Ishizaki, T.5    Narumiya, S.6
  • 15
    • 0035836791 scopus 로고    scopus 로고
    • Rho signals to cell growth and apoptosis
    • DOI 10.1016/S0304-3835(01)00412-8, PII S0304383501004128
    • Aznar S, Lacal JC. Rho signals to cell growth and apoptosis. Cancer Lett. 2001;165:1-10. (Pubitemid 32206651)
    • (2001) Cancer Letters , vol.165 , Issue.1 , pp. 1-10
    • Aznar, S.1    Lacal, J.C.2
  • 16
    • 56749175040 scopus 로고    scopus 로고
    • How peptide hormone vesicles are transported to the secretion site for exocytosis
    • Park JJ, Loh YP. How peptide hormone vesicles are transported to the secretion site for exocytosis. Mol Endocrinol. 2008;22:2583-2595.
    • (2008) Mol Endocrinol. , vol.22 , pp. 2583-2595
    • Park, J.J.1    Loh, Y.P.2
  • 17
    • 77954412580 scopus 로고    scopus 로고
    • Rho-kinase inhibitor, fasudil, suppresses glioblastoma cell line progression in vitro and in vivo
    • Deng L, Li G, Li R, Liu Q, He Q, Zhang J. Rho-kinase inhibitor, fasudil, suppresses glioblastoma cell line progression in vitro and in vivo. Cancer Biol Ther. 2010;9:875-884.
    • (2010) Cancer Biol Ther. , vol.9 , pp. 875-884
    • Deng, L.1    Li, G.2    Li, R.3    Liu, Q.4    He, Q.5    Zhang, J.6
  • 18
    • 84869401508 scopus 로고    scopus 로고
    • Fasudil, a Rho-kinase inhibitor, protects against excessive endurance exercise training-induced cardiac hypertrophy, apoptosis and fibrosis in rats
    • Ho TJ, Huang CC, Huang CY, Lin WT. Fasudil, a Rho-kinase inhibitor, protects against excessive endurance exercise training-induced cardiac hypertrophy, apoptosis and fibrosis in rats. Eur J Appl Physiol. 2011;23:1037-1045.
    • (2011) Eur J Appl Physiol. , vol.23 , pp. 1037-1045
    • Ho, T.J.1    Huang, C.C.2    Huang, C.Y.3    Lin, W.T.4
  • 19
    • 84862832422 scopus 로고    scopus 로고
    • The Rho-kinase inhibitor inhibits proliferation and metastasis of small cell lung cancer
    • Yang X, Di J, Zhang Y, Zhang S, Lu J, Liu J, et al. The Rho-kinase inhibitor inhibits proliferation and metastasis of small cell lung cancer. Biomed Pharmacother. 2012;66:221-227.
    • (2012) Biomed Pharmacother. , vol.66 , pp. 221-227
    • Yang, X.1    Di, J.2    Zhang, Y.3    Zhang, S.4    Lu, J.5    Liu, J.6
  • 20
    • 84863080020 scopus 로고    scopus 로고
    • Inhibition of the Rho/ROCK pathway enhances the efficacy of cisplatin through the blockage of hypoxia-inducible factor-1α in human ovarian cancer cells
    • Ohta T, Takahashi T, Shibuya T, Amita M, Henmi N, Takahashi K, et al. Inhibition of the Rho/ROCK pathway enhances the efficacy of cisplatin through the blockage of hypoxia-inducible factor-1α in human ovarian cancer cells. Cancer Biol Ther. 2012;13:25-33.
    • (2012) Cancer Biol Ther. , vol.13 , pp. 25-33
    • Ohta, T.1    Takahashi, T.2    Shibuya, T.3    Amita, M.4    Henmi, N.5    Takahashi, K.6
  • 21
    • 19544380723 scopus 로고    scopus 로고
    • Modulation of CXCL14 (BRAK) expression in prostate cancer
    • DOI 10.1002/pros.20215
    • Schwarze SR, Luo J, Isaacs WB, Jarrard DF. Modulation of CXCL14 (BRAK) expression in prostate cancer. Prostate. 2005;64:67-74. (Pubitemid 40734740)
    • (2005) Prostate , vol.64 , Issue.1 , pp. 67-74
    • Schwarze, S.R.1    Luo, J.2    Isaacs, W.B.3    Jarrard, D.F.4
  • 22
    • 0028800305 scopus 로고
    • Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation
    • Khosravi-Far R, Solski PA, Clark GJ, Kinch MS, Der CJ. Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation. Mol Cell Biol. 1995;15:6443.
    • (1995) Mol Cell Biol. , vol.15 , pp. 6443
    • Khosravi-Far, R.1    Solski, P.A.2    Clark, G.J.3    Kinch, M.S.4    Der, C.J.5
  • 24
    • 0033081753 scopus 로고    scopus 로고
    • Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton
    • DOI 10.1093/emboj/18.3.578
    • Ren XD, Kiosses WB, Schwartz MA. Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton. EMBO J. 1999;18:578-585. (Pubitemid 29057242)
    • (1999) EMBO Journal , vol.18 , Issue.3 , pp. 578-585
    • Ren, X.-D.1    Kiosses, W.B.2    Schwartz, M.A.3
  • 25
    • 34047126537 scopus 로고    scopus 로고
    • 2+-dependent dephosphorylation of cofilin that is independent of dense granule secretion and aggregation
    • DOI 10.1016/j.bcmd.2007.01.002, PII S1079979607000241
    • Pandey D, Goyal P, Siess W. Lysophosphatidic acid stimulation of platelets rapidly induces Ca2+-dependent dephosphorylation of cofilin that is independent of dense granule secretion and aggregation. Blood Cells Mol Dis. 2007;38:269-279. (Pubitemid 46518177)
    • (2007) Blood Cells, Molecules, and Diseases , vol.38 , Issue.3 , pp. 269-279
    • Pandey, D.1    Goyal, P.2    Siess, W.3
  • 27
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell. 2000;100:57-70. (Pubitemid 30046295)
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 28
    • 0036515416 scopus 로고    scopus 로고
    • Emerging molecular markers of cancer
    • Sidransky D. Emerging molecular markers of cancer. Nat Rev Cancer. 2002;2:210-219. (Pubitemid 37328790)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.3 , pp. 210-219
    • Sidransky, D.1
  • 29
    • 0036084359 scopus 로고    scopus 로고
    • TGF-β antagonists: Why suppress a tumor suppressor?
    • DOI 10.1172/JCI200215970
    • Akhurst RJ. TGF-beta antagonists: why suppress a tumor suppressor? J Clin Invest. 2002;109:1533-1536. (Pubitemid 34663514)
    • (2002) Journal of Clinical Investigation , vol.109 , Issue.12 , pp. 1533-1536
    • Akhurst, R.J.1
  • 30
    • 41149094081 scopus 로고    scopus 로고
    • A balance between NF-Y and p53 governs the pro- and anti-apoptotic transcriptional response
    • DOI 10.1093/nar/gkm1046
    • Benatti P, Basile V, Merico D, Fantoni LI, Tagliafico E, Imbriano C. A balance between NF-Y and p53 governs the pro- and anti-apoptotic transcriptional response. Nucleic Acids Res. 2008; 36:1415-1428. (Pubitemid 351426096)
    • (2008) Nucleic Acids Research , vol.36 , Issue.5 , pp. 1415-1428
    • Benatti, P.1    Basile, V.2    Merico, D.3    Fantoni, L.I.4    Tagliafico, E.5    Imbriano, C.6
  • 31
    • 41749091574 scopus 로고    scopus 로고
    • Applications for ROCK kinase inhibition
    • Olson MF. Applications for ROCK kinase inhibition. Curr Opin Cell Biol. 2008;20:242-248.
    • (2008) Curr Opin Cell Biol. , vol.20 , pp. 242-248
    • Olson, M.F.1
  • 32
    • 68549122708 scopus 로고    scopus 로고
    • Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion
    • Narumiya S, Tanji M, Ishizaki T. Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion. Cancer Metastasis Rev. 2009;28:65-76.
    • (2009) Cancer Metastasis Rev. , vol.28 , pp. 65-76
    • Narumiya, S.1    Tanji, M.2    Ishizaki, T.3
  • 33
    • 39849105533 scopus 로고    scopus 로고
    • Rho GTPases of the RhoBTB subfamily and tumorigenesis
    • DOI 10.1111/j.1745-7254.2008.00773.x
    • Berthold J, Schenkova K, Rivero F. Rho GTPases of the RhoBTB subfamily and tumorigenesis. Acta Pharmacol Sin. 2008;29:285-295. (Pubitemid 351316996)
    • (2008) Acta Pharmacologica Sinica , vol.29 , Issue.3 , pp. 285-295
    • Berthold, J.1    Schenkova, K.2    Rivero, F.3
  • 35
    • 56649094387 scopus 로고    scopus 로고
    • The atypical Rho GTPase RhoBTB2 is required for expression of the chemokine CXCL14 in normal and cancerous epithelial cells
    • McKinnon CM, Lygoe KA, Skelton L, Mitter R, Mellor H. The atypical Rho GTPase RhoBTB2 is required for expression of the chemokine CXCL14 in normal and cancerous epithelial cells. Oncogene. 2008;27:6856-6865.
    • (2008) Oncogene. , vol.27 , pp. 6856-6865
    • McKinnon, C.M.1    Lygoe, K.A.2    Skelton, L.3    Mitter, R.4    Mellor, H.5
  • 37
    • 0042887042 scopus 로고    scopus 로고
    • The emerging role of lysophosphatidic acid in cancer
    • DOI 10.1038/nrc1143
    • Mills GB, Moolenaar WH. The emerging role of lysophosphatidic acid in cancer. Nat Rev Cancer. 2003;3:582-591. (Pubitemid 37328830)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.8 , pp. 582-591
    • Mills, G.B.1    Moolenaar, W.H.2
  • 38
    • 70449769732 scopus 로고    scopus 로고
    • ATX-LPA receptor axis in inflammation and cancer
    • Liu S, Murph M, Panupinthu N, Mills GB. ATX-LPA receptor axis in inflammation and cancer. Cell Cycle. 2009;8:3695-3701.
    • (2009) Cell Cycle. , vol.8 , pp. 3695-3701
    • Liu, S.1    Murph, M.2    Panupinthu, N.3    Mills, G.B.4
  • 40
    • 0034602959 scopus 로고    scopus 로고
    • Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop
    • DOI 10.1074/jbc.275.5.3577
    • Ohashi K, Nagata K, Maekawa M, Ishizaki T, Narumiya S, Mizuno K. Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop. J Biol Chem. 2000;275:3577-3582. (Pubitemid 30083067)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.5 , pp. 3577-3582
    • Ohashi, K.1    Nagata, K.2    Maekawa, M.3    Ishizaki, T.4    Narumiya, S.5    Mizuno, K.6
  • 41
    • 4744337757 scopus 로고    scopus 로고
    • LIM kinase 1: Evidence for a role in the regulation of intracellular vesicle trafficking of lysosomes and endosomes in human breast cancer cells
    • DOI 10.1078/0171-9335-00382
    • Nishimura Y, Yoshioka K, Bernard O, Himeno M, Itoh K. LIM kinase 1: evidence for a role in the regulation of intracellular vesicle trafficking of lysosomes and endosomes in human breast cancer cells. Eur J Cell Biol. 2004;83:369-380. (Pubitemid 39307174)
    • (2004) European Journal of Cell Biology , vol.83 , Issue.7 , pp. 369-380
    • Nishimura, Y.1    Yoshioka, K.2    Bernard, O.3    Himeno, M.4    Itoh, K.5
  • 42
    • 0028026746 scopus 로고
    • Molecular motors are differentially distributed on Golgi membranes from polarized epithelial cells
    • DOI 10.1083/jcb.126.3.661
    • Fath KR, Trimbur GM, Burgess DR. Molecular motors are differentially distributed on Golgi membranes from polarized epithelial cells. J Cell Biol. 1994;126:661-675. (Pubitemid 24241380)
    • (1994) Journal of Cell Biology , vol.126 , Issue.3 , pp. 661-675
    • Fath, K.R.1    Trimbur, G.M.2    Burgess, D.R.3
  • 43
    • 0029163054 scopus 로고
    • Molecular motors, membrane movements and physiology: Emerging roles for myosins
    • Hasson T, Mooseker MS. Molecular motors, membrane movements and physiology: emerging roles for myosins. Curr Opin Cell Biol. 1995;7:587-594.
    • (1995) Curr Opin Cell Biol. , vol.7 , pp. 587-594
    • Hasson, T.1    Mooseker, M.S.2
  • 44
    • 0028942256 scopus 로고
    • Actin- and microtubule-dependent organelle motors: Interrelationships between the two motility systems
    • Langford GM. Actin- and microtubule-dependent organelle motors: interrelationships between the two motility systems. Curr Opin Cell Biol. 1995;7:82-88.
    • (1995) Curr Opin Cell Biol. , vol.7 , pp. 82-88
    • Langford, G.M.1
  • 47
    • 34447640943 scopus 로고    scopus 로고
    • A postmarketing surveillance study of fasudil treatment after aneurysmal subarachnoid hemorrhage
    • DOI 10.1016/j.surneu.2006.10.037, PII S0090301906009931
    • Suzuki Y, Shibuya M, Satoh S, Sugimoto Y, Takakura K. A post-marketing surveillance study of fasudil treatment after aneurysmal subarachnoid hemorrhage. Surg Neurol. 2007;68:126-131. (Pubitemid 47087900)
    • (2007) Surgical Neurology , vol.68 , Issue.2 , pp. 126-131
    • Suzuki, Y.1    Shibuya, M.2    Satoh, S.-i.3    Sugimoto, Y.4    Takakura, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.