메뉴 건너뛰기




Volumn 24, Issue 12, 2012, Pages 1430-1437

Colorectal neuroendocrine carcinomas and adenocarcinomas share oncogenic pathways. A clinico-pathologic study of 12 cases

Author keywords

BRAF; colorectal cancer; KRAS; neuroendocrine tumor; oncogenesis

Indexed keywords

BEVACIZUMAB; CAPECITABINE; CISPLATIN; ETOPOSIDE; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; OXALIPLATIN;

EID: 84869441872     PISSN: 0954691X     EISSN: 14735687     Source Type: Journal    
DOI: 10.1097/MEG.0b013e3283583c87     Document Type: Article
Times cited : (49)

References (46)
  • 3
    • 84869482730 scopus 로고    scopus 로고
    • WHO Classification Of Tumours Of The Digestive System, World Health Organization, International Agency for Research of Cancer
    • Bosman FT, Carneiro F, Hruban RH, Theise ND. WHO classification of tumours of the digestive system. Lyon, France: World Health Organization, International Agency for Research of Cancer; 2010.
    • (2010) Lyon France
    • Bosman, F.T.1    Carneiro, F.2    Hruban, R.H.3    Theise, N.D.4
  • 4
    • 34848828173 scopus 로고    scopus 로고
    • TNM staging of midgut and hindgut (neuro) endocrine tumors: A consensus proposal including a grading system
    • Rindi G, Klöppel G, Couvelard A, Komminoth P, Körner M, Lopes JM, et al. TNM staging of midgut and hindgut (neuro) endocrine tumors: a consensus proposal including a grading system. Virchows Arch 2007; 451:757-762.
    • (2007) Virchows Arch , vol.451 , pp. 757-762
    • Rindi, G.1    Klöppel, G.2    Couvelard, A.3    Komminoth, P.4    Körner, M.5    Lopes, J.M.6
  • 6
    • 1342341543 scopus 로고
    • Carcinoid tumors and the mixed (composite) glandular-endocrine cell carcinomas
    • Lewin K. Carcinoid tumors and the mixed (composite) glandular-endocrine cell carcinomas. Am J Surg Pathol 1987; 11 (Suppl 1):71-86.
    • (1987) Am J Surg Pathol , vol.11 , Issue.SUPPL. 1 , pp. 71-86
    • Lewin, K.1
  • 7
    • 84859087024 scopus 로고    scopus 로고
    • Mixed adenoneuroendocrine carcinomas (MANECs) of the gastrointestinal tract: An update
    • Rosa SL, Marando A, Sessa F, Capella C. Mixed adenoneuroendocrine carcinomas (MANECs) of the gastrointestinal tract: an update. Cancers 2012; 4:11-30.
    • (2012) Cancers , vol.4 , pp. 11-30
    • Rosa, S.L.1    Marando, A.2    Sessa, F.3    Capella, C.4
  • 8
    • 34447266923 scopus 로고    scopus 로고
    • An unusual case of colonic mixed adenoendocrine carcinoma: Collision versus composite tumor. A case report and review of the literature
    • Pecorella I, Memeo L, Ciardi A, H Rotterdam. An unusual case of colonic mixed adenoendocrine carcinoma: collision versus composite tumor. A case report and review of the literature. Ann Diagn Pathol 2007; 11:285-290.
    • (2007) Ann Diagn Pathol , vol.11 , pp. 285-290
    • Pecorella, I.1    Memeo, L.2    Ciardi, A.3    Rotterdam, H.4
  • 9
    • 35348966924 scopus 로고    scopus 로고
    • Primary colorectal small cell carcinoma: A clinicopathological and immunohistochemical study of 10 cases
    • Demellawy El D, Khalifa MA, Ismiil N,Wong S, Ghorab Z. Primary colorectal small cell carcinoma: a clinicopathological and immunohistochemical study of 10 cases. Diagn Pathol 2007; 2:35.
    • (2007) Diagn Pathol , vol.2 , pp. 35
    • Demellawy El, D.1    Khalifa, M.A.2    Ismiil, N.3    Wong, S.4    Ghorab, Z.5
  • 10
    • 33749318805 scopus 로고    scopus 로고
    • Composite adenocarcinoma and large cell neuroendocrine carcinoma of the rectum
    • Makino A, Serra S, Chetty R. Composite adenocarcinoma and large cell neuroendocrine carcinoma of the rectum. Virchows Arch 2006; 448: 644-647.
    • (2006) Virchows Arch , vol.448 , pp. 644-647
    • Makino, A.1    Serra, S.2    Chetty, R.3
  • 13
    • 0041731800 scopus 로고    scopus 로고
    • Adenoma, adenocarcinoma and mixed carcinoid-adenocarcinoma arising in a small lesion of the colon
    • Jiao YF, Nakamura SI, Arai T, Sugai T, Uesugi N, Habano W, et al. Adenoma, adenocarcinoma and mixed carcinoid-adenocarcinoma arising in a small lesion of the colon. Pathol Int 2003; 53:457-462.
    • (2003) Pathol Int , vol.53 , pp. 457-462
    • Jiao, Y.F.1    Nakamura, S.I.2    Arai, T.3    Sugai, T.4    Uesugi, N.5    Habano, W.6
  • 14
    • 0042308355 scopus 로고    scopus 로고
    • Microallelotyping defines the monoclonal or the polyclonal origin of mixed and collision endocrine-exocrine tumors of the gut
    • Furlan D, Cerutti R, Genasetti A, Pelosi G, Uccella S, La Rosa S, et al. Microallelotyping defines the monoclonal or the polyclonal origin of mixed and collision endocrine-exocrine tumors of the gut. Lab Invest 2003; 83:963-971.
    • (2003) Lab Invest , vol.83 , pp. 963-971
    • Furlan, D.1    Cerutti, R.2    Genasetti, A.3    Pelosi, G.4    Uccella, S.5    La Rosa, S.6
  • 15
    • 0032589525 scopus 로고    scopus 로고
    • Rectal adenocarcinoid with lymph node metastasis
    • Yagihashi N, Koyama M, Yagihashi S. Rectal adenocarcinoid with lymph node metastasis. Pathol Int 1999; 49:563-565.
    • (1999) Pathol Int , vol.49 , pp. 563-565
    • Yagihashi, N.1    Koyama, M.2    Yagihashi, S.3
  • 16
    • 0344069725 scopus 로고    scopus 로고
    • Amphicrine tumor
    • Mándoky L. Amphicrine tumor. Pathol Oncol Res 1999; 5:239-244.
    • (1999) Pathol Oncol Res , vol.5 , pp. 239-244
    • Mándoky, L.1
  • 18
    • 0031842375 scopus 로고    scopus 로고
    • Neuroendocrine neoplasms arising in inflammatory bowel disease: A report of 14 cases
    • Sigel JE, Goldblum Jr. Neuroendocrine neoplasms arising in inflammatory bowel disease: a report of 14 cases. Mod Pathol 1998; 11:537-542.
    • (1998) Mod Pathol , vol.11 , pp. 537-542
    • Sigel, J.E.1    Goldblum, J.R.2
  • 19
    • 0029551998 scopus 로고    scopus 로고
    • Ectopic adrenocorticotropin syndrome associated with undifferentiated carcinoma of the colon showing multidirectional neuroendocrine, exocrine, and squamous differentiation
    • Onishi R, Sano T, Nakamura Y, Namiuchi S, Sawada S, Ihara C, et al. Ectopic adrenocorticotropin syndrome associated with undifferentiated carcinoma of the colon showing multidirectional neuroendocrine, exocrine, and squamous differentiation. Virchows Arch 1996; 427:537-541.
    • (1996) Virchows Arch , vol.427 , pp. 537-541
    • Onishi, R.1    Sano, T.2    Nakamura, Y.3    Namiuchi, S.4    Sawada, S.5    Ihara, C.6
  • 20
    • 0027477682 scopus 로고
    • Mixed adenocarcinoma/carcinoid tumour of large bowel in a patient with Crohn's disease
    • Hock YL, Scott KW, Grace RH. Mixed adenocarcinoma/carcinoid tumour of large bowel in a patient with Crohn's disease. J Clin Pathol 1993; 46: 183-185.
    • (1993) J Clin Pathol , vol.46 , pp. 183-185
    • Hock, Y.L.1    Scott, K.W.2    Grace, R.H.3
  • 22
    • 0025305378 scopus 로고
    • Small cell undifferentiated ('neuroendocrine') carcinoma of the colon
    • Sarsfield P, Anthony PP. Small cell undifferentiated ('neuroendocrine') carcinoma of the colon. Histopathology 1990; 16:357-363.
    • (1990) Histopathology , vol.16 , pp. 357-363
    • Sarsfield, P.1    Anthony, P.P.2
  • 23
    • 0025264238 scopus 로고
    • Composite (adenocarcinoid) tumors of the gastrointestinal tract
    • Levendoglu H, Cox CA, Nadimpalli V. Composite (adenocarcinoid) tumors of the gastrointestinal tract. Dig Dis Sci 1990; 35:519-525.
    • (1990) Dig Dis Sci , vol.35 , pp. 519-525
    • Levendoglu, H.1    Cox, C.A.2    Nadimpalli, V.3
  • 24
    • 0025013764 scopus 로고
    • Neuroendocrine carcinoma of the colon and rectum. A clinicopathologic, ultrastructural, and immunohistochemical study of 24 cases
    • Gaffey MJ, Mills SE, Lack EE. Neuroendocrine carcinoma of the colon and rectum. A clinicopathologic, ultrastructural, and immunohistochemical study of 24 cases. Am J Surg Pathol 1990; 14:1010-1023.
    • (1990) Am J Surg Pathol , vol.14 , pp. 1010-1023
    • Gaffey, M.J.1    Mills, S.E.2    Lack, E.E.3
  • 25
    • 0023727001 scopus 로고
    • Composite glandular-carcinoid tumors of the colon and rectum. Report of two cases
    • Moyana TN, Qizilbash AH, Murphy F. Composite glandular-carcinoid tumors of the colon and rectum. Report of two cases. Am J Surg Pathol 1988; 12:607-611.
    • (1988) Am J Surg Pathol , vol.12 , pp. 607-611
    • Moyana, T.N.1    Qizilbash, A.H.2    Murphy, F.3
  • 26
    • 0023139579 scopus 로고
    • Small cell neuroendocrine carcinoma of the colon and rectum: Clinical, histologic, and ultrastructural study and immunohistochemical comparison with cloacogenic carcinoma
    • Wick MR,Weatherby RP,Weiland LH. Small cell neuroendocrine carcinoma of the colon and rectum: clinical, histologic, and ultrastructural study and immunohistochemical comparison with cloacogenic carcinoma. Hum Pathol 1987; 18:9-21.
    • (1987) Hum Pathol , vol.18 , pp. 9-21
    • Wick, M.R.1    Weatherby, R.P.2    Weiland, L.H.3
  • 27
    • 0023521864 scopus 로고
    • Mixed adenocarcinoma and carcinoid tumour of the colon. A report of 4 cases with postulates on histogenesis
    • Knight BK, Hayes MM. Mixed adenocarcinoma and carcinoid tumour of the colon. A report of 4 cases with postulates on histogenesis. S Afr Med J 1987; 72:708-710.
    • (1987) S Afr Med J , vol.72 , pp. 708-710
    • Knight, B.K.1    Hayes, M.M.2
  • 28
    • 0022515907 scopus 로고
    • Enteroendocrine cell hyperplasia, carcinoid tumours and adenocarcinoma in long-standing ulcerative colitis
    • Gledhill A, Hall PA, Cruse JP, Pollock DJ. Enteroendocrine cell hyperplasia, carcinoid tumours and adenocarcinoma in long-standing ulcerative colitis. Histopathology 1986; 10:501-508.
    • (1986) Histopathology , vol.10 , pp. 501-508
    • Gledhill, A.1    Hall, P.A.2    Cruse, J.P.3    Pollock, D.J.4
  • 29
    • 0022260162 scopus 로고
    • Composite carcinomacarcinoid tumors of the gastrointestinal tract. A morphologic, histochemical, and immunocytochemical study
    • Klappenbach RS, Kurman RJ, Sinclair CF, James LP. Composite carcinomacarcinoid tumors of the gastrointestinal tract. A morphologic, histochemical, and immunocytochemical study. Am J Clin Pathol 1985; 84:137-143.
    • (1985) Am J Clin Pathol , vol.84 , pp. 137-143
    • Klappenbach, R.S.1    Kurman, R.J.2    Sinclair, C.F.3    James, L.P.4
  • 30
    • 0021858609 scopus 로고
    • Stem cell carcinoma of the colon and rectum. Report of two cases and review of the literature
    • Palvio DH, Sørensen FB, Kløve-Mogensen M. Stem cell carcinoma of the colon and rectum. Report of two cases and review of the literature. Dis Colon Rectum 1985; 28:440-445.
    • (1985) Dis Colon Rectum , vol.28 , pp. 440-445
    • Palvio, D.H.1    Sørensen, F.B.2    Kløve-Mogensen, M.3
  • 31
    • 0020507795 scopus 로고
    • Adenosquamous carcinoma and carcinoidal differentiation of the colon. Report of a case
    • Peonim V, Thakerngpol K, Pacharee P, Stitnimankarn T. Adenosquamous carcinoma and carcinoidal differentiation of the colon. Report of a case. Cancer 1983; 52:1122-1125.
    • (1983) Cancer , vol.52 , pp. 1122-1125
    • Peonim, V.1    Thakerngpol, K.2    Pacharee, P.3    Stitnimankarn, T.4
  • 32
    • 0014606951 scopus 로고
    • Mixed carcinoid and mucus-secreting intestinal tumors
    • Hernandez FJ, Reid JD. Mixed carcinoid and mucus-secreting intestinal tumors. Arch Pathol 1969; 88:489-496.
    • (1969) Arch Pathol , vol.88 , pp. 489-496
    • Hernandez, F.J.1    Reid, J.D.2
  • 33
    • 0014151308 scopus 로고
    • Composite carcinoid tumor (argentaffinomaadenocarcinoma) of the colon: Report of 2 cases
    • Bates HR, Belter LF. Composite carcinoid tumor (argentaffinomaadenocarcinoma) of the colon: report of 2 cases. Dis Colon Rectum 1967; 10:467-470.
    • (1967) Dis Colon Rectum , vol.10 , pp. 467-470
    • Bates, H.R.1    Belter, L.F.2
  • 34
    • 79953053905 scopus 로고    scopus 로고
    • Colorectal glandular-neuroendocrine mixed tumor: Pathologic spectrum and clinical implications
    • Li Y, Yau A, Schaeffer D, Magliocco A, Gui X, Urbanski S, et al. Colorectal glandular-neuroendocrine mixed tumor: pathologic spectrum and clinical implications. Am J Surg Pathol 2011; 35:413-425.
    • (2011) Am J Surg Pathol , vol.35 , pp. 413-425
    • Li, Y.1    Yau, A.2    Schaeffer, D.3    Magliocco, A.4    Gui, X.5    Urbanski, S.6
  • 35
    • 77955277111 scopus 로고    scopus 로고
    • Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: A retrospective consortium analysis
    • De RoockW, Claes B, Bernasconi D, De Schutter J, Biesmans B, Fountzilas G, et al. Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis. Lancet Oncol 2010; 11:753-762.
    • (2010) Lancet Oncol , vol.11 , pp. 753-762
    • De Roock, W.1    Claes, B.2    Bernasconi, D.3    De Schutter, J.4    Biesmans, B.5    Fountzilas, G.6
  • 36
    • 84869386298 scopus 로고    scopus 로고
    • ALK chromosomal alterations in colon cancer patients
    • Montagut C, Galvan A, Gallen M. ALK chromosomal alterations in colon cancer patients. J Clin Oncol 2010; 28:15.
    • (2010) J Clin Oncol , vol.28 , pp. 15
    • Montagut, C.1    Galvan, A.2    Gallen, M.3
  • 37
    • 84858961916 scopus 로고    scopus 로고
    • Competitive allele specific TaqMan PCR for KRAS, BRAF and EGFR mutation detection in clinical formalin fixed paraffin embedded samples
    • Didelot A, Le Corre D, Luscan A, Cazes A, Pallier K, Emile J-F, et al. Competitive allele specific TaqMan PCR for KRAS, BRAF and EGFR mutation detection in clinical formalin fixed paraffin embedded samples. Exp Mol Pathol 2012; 92:275-280.
    • (2012) Exp Mol Pathol , vol.92 , pp. 275-280
    • Didelot, A.1    Le Corre, D.2    Luscan, A.3    Cazes, A.4    Pallier, K.5    Emile, J.-F.6
  • 39
    • 84857792328 scopus 로고    scopus 로고
    • Histologic subtypes, immunohistochemistry, FISH or molecular screening for the accurate diagnosis of ALK-rearrangement in lung cancer: A comprehensive study of Caucasian non-smokers
    • Just P-A, Cazes A, Audebourg A, Cessot A, Pallier K, Danel C, et al. Histologic subtypes, immunohistochemistry, FISH or molecular screening for the accurate diagnosis of ALK-rearrangement in lung cancer: a comprehensive study of Caucasian non-smokers. Lung Cancer 2011; 76:309-315.
    • (2011) Lung Cancer , vol.76 , pp. 309-315
    • Just, P.-A.1    Cazes, A.2    Audebourg, A.3    Cessot, A.4    Pallier, K.5    Danel, C.6
  • 40
    • 42649089083 scopus 로고    scopus 로고
    • Is nonsmall cell type high-grade neuroendocrine carcinoma of the tubular gastrointestinal tract a distinct disease entity?
    • Shia J, Tang LH, Weiser MR, Brenner B, Adsay NV, Stelow EB, et al. Is nonsmall cell type high-grade neuroendocrine carcinoma of the tubular gastrointestinal tract a distinct disease entity? Am J Surg Pathol 2008; 32:719-731.
    • (2008) Am J Surg Pathol , vol.32 , pp. 719-731
    • Shia, J.1    Tang, L.H.2    Weiser, M.R.3    Brenner, B.4    Adsay, N.V.5    Stelow, E.B.6
  • 41
    • 84859041362 scopus 로고    scopus 로고
    • Colorectal poorly differentiated neuroendocrine carcinomas and mixed adenoneuroendocrine carcinomas: Insights into the diagnostic immunophenotype, assessment of methylation profile, and search for prognostic markers
    • La Rosa S, Marando A, Furlan D, Sahnane N, Capella C. Colorectal poorly differentiated neuroendocrine carcinomas and mixed adenoneuroendocrine carcinomas: insights into the diagnostic immunophenotype, assessment of methylation profile, and search for prognostic markers. Am J Surg Pathol 2012; 36:601-611.
    • (2012) Am J Surg Pathol , vol.36 , pp. 601-611
    • La Rosa, S.1    Marando, A.2    Furlan, D.3    Sahnane, N.4    Capella, C.5
  • 42
    • 82455175633 scopus 로고    scopus 로고
    • Evaluation and treatment of patients with nonsmall cell lung cancer
    • Carr LL, Finigan JH, Kern JA. Evaluation and treatment of patients with nonsmall cell lung cancer. Med Clin North Am 2011; 95:1041-1054.
    • (2011) Med Clin North Am , vol.95 , pp. 1041-1054
    • Carr, L.L.1    Finigan, J.H.2    Kern, J.A.3
  • 43
    • 79952279828 scopus 로고    scopus 로고
    • DAXX/ ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors
    • Jiao Y, Shi C, Edil BH, de Wilde RF, Klimstra DS, Maitra A, et al. DAXX/ ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors. Science 2011; 331:1199-1203.
    • (2011) Science , vol.331 , pp. 1199-1203
    • Jiao, Y.1    Shi, C.2    Edil, B.H.3    De Wilde, R.F.4    Klimstra, D.S.5    Maitra, A.6
  • 44
    • 0030882999 scopus 로고    scopus 로고
    • Concordance of genetic alterations in poorly differentiated colorectal neuroendocrine carcinomas and associated adenocarcinomas
    • Vortmeyer AO, Lubensky IA, Merino MJ,Wang CY, Pham T, Furth EE, et al. Concordance of genetic alterations in poorly differentiated colorectal neuroendocrine carcinomas and associated adenocarcinomas. J Natl Cancer Inst 1997; 89:1448-1453.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 1448-1453
    • Vortmeyer, A.O.1    Lubensky, I.A.2    Merino, M.J.3    Wang, C.Y.4    Pham, T.5    Furth, E.E.6
  • 46
    • 77955198120 scopus 로고    scopus 로고
    • The NANETS consensus guidelines for the diagnosis and management of poorly differentiated (high-grade) extrapulmonary neuroendocrine carcinomas
    • North American Neuroendocrine Tumor Society (NANETS)
    • Strosberg JR, Coppola D, Klimstra DS, Phan AT, Kulke MH, Wiseman GA, Kvols LK. North American Neuroendocrine Tumor Society (NANETS). The NANETS consensus guidelines for the diagnosis and management of poorly differentiated (high-grade) extrapulmonary neuroendocrine carcinomas. Pancreas 2010; 39:799-780.
    • (2010) Pancreas , vol.39 , pp. 799-780
    • Strosberg, J.R.1    Coppola, D.2    Klimstra, D.S.3    Phan, A.T.4    Kulke, M.H.5    Wiseman, G.A.6    Kvols, L.K.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.