Ectopic adrenocorticotropin syndrome associated with undifferentiated carcinoma of the colon showing multidirectional neuroendocrine, exocrine, and squamous differentiation

Virchows Archiv

Volumn 427, Issue 5, 1996, Pages 537-541

  Onishi, Rie ^a   Sano, Toshiaki ^b   Nakamura, Yoshio ^a   Namiuchi, Shunzo ^b   Sawada, Shinji ^b   Ihara, Chihiro ^a   Shimatsu, Akira ^b  

^a Kitano Hospital   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Colon cancer; Ectopic acth syndrome; Multidirectional differentiation; Undifferentiated carcinoma

Indexed keywords

CORTICOTROPIN; HYDROCORTISONE;

ADRENAL DISEASE; ADULT; ARTICLE; ASCENDING COLON; BARIUM ENEMA; CANCER DIAGNOSIS; CANCER SURGERY; CASE REPORT; CELL DIFFERENTIATION; COLON CARCINOMA; COMPUTER ASSISTED TOMOGRAPHY; CORTICOTROPIN BLOOD LEVEL; CORTICOTROPIN RELEASE; DISEASE ASSOCIATION; ECTOPIC CORTICOTROPIN PRODUCTION; EXOCRINE CELL; FEMALE; HISTOPATHOLOGY; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYPOKALEMIA; IMMUNOHISTOCHEMISTRY; LIVER METASTASIS; METABOLIC ALKALOSIS; NEUROSECRETORY CELL; PRIORITY JOURNAL; RADIOIMMUNOASSAY; SQUAMOUS CELL;

ACTH SYNDROME, ECTOPIC; CARCINOMA; CELL DIFFERENTIATION; COLONIC NEOPLASMS; EPITHELIUM; EXOCRINE GLANDS; FEMALE; HUMANS; MIDDLE AGED; NEUROENDOCRINE TUMORS;

EID: 0029551998     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00199515     Document Type: Article

References (14)

1. Imura H, Matsukura S, Yamamoto H, Hirata Y, Nakai Y, Endo J, Tanaka A, Nakamura M (1975) Studies on ectopic ACTHproducing tumors. II. Clinical and biochemical features of 30 cases. Cancer 35:1430-1437
2. Miura K, Demura H, Sato E, Sasano N, Shimizu N (1970) A case of ACTH secreting cancer of the colon. J Clin Endocrinol Metab 31:591-595
3. Balsam A, Berstein B, Goldman J, Sachs BA, Rifkin H (1972) Ectopic adrenocorticotropin syndrome associated with carcinoma of the colon. Gastroenterology 62:636-641
4. Suda T, Demura H, Demura R, Wakabayashi I, Nomura K, Odagiri E, Shizume K (1977) Corticotropin-releasing factorlike activity in ACTH producing tumors. J Clin Endocrinol Metab 44:440-446
5. Coates PJ, Doniach I, Howlett TA, Rees LH, Besser GM (1986) Immunocytochemical study of 18 tumors causing ectopic Cushing's syndrome. J Clin Pathol 39:955-960
6. Remick SC, Hafez GR, Carbone PP (1987) Extrapulmonary small cell carcinoma. A review of the literature with emphasis on therapy and outcome. Medicine 66:457-471
7. Sterling RK (1993) Ectopic ACTH syndrome associated with anorectal carcinoma. Report of a case and review of the literature. Dig Dis Sei 38:955-959
8. Shimatsu A, Kato Y, Tanaka I, Nakai Y, Fukunaga M, Imura H (1983) Plasma calcitonin and ACTH responses to lysine vasopressin, calcium and pentagastrin in a patient with medullary thyroid carcinoma associated with Cushing's syndrome. Clin Endocrinol 18:119-125
9. Clery AP, Dockerty MB, Waugh JM (1961) Small cell carcinoma of the colon and rectum. Arch Surg 83:164-172
10. Gould VE, Chejfec G (1978) Neuroendocrine carcinoma of the colon. Am J Surg Pathol 2:31-38
11. Staren ED, Gould VE, Warren WH, Wool NL, Bines S, Baker J, Bonomi P, Roseman DL, Economou SG (1988) Neuroendocrine carcinomas of the colon and rectum. A clinicopathologic evaluation. Surgery 104:1080-1089
12. Defold CR, Menefee JK, Nicholson WE, Orth DN (1988) Proopiomelanocortin gene is expressed in many normal human tissues and tumors not associated with ectopic adrenocorticotropin syndrome. Mol Endocrinol 2:862-870
13. Damjanov I, Amenta PS, Bosnian FT (1983) Undifferentiated carcinoma of the colon containing exocrine, neuroendocrine and squamous cells. Virchows Arch [A] 401:57-66
14. Petrelli M, Tetangco E, Reid JD (1981) Carcinoma of the colon with Undifferentiated, carcinoid, and squamous cell features. Am J Clin Pathol 75:581-584