메뉴 건너뛰기




Volumn 30, Issue 32, 2012, Pages 3909-3912

Biologically targeted therapies plus chemotherapy plus radiotherapy in stage III non-small-cell lung cancer: A case of the Icarus syndrome?

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; CARBOPLATIN; CISPLATIN; DOCETAXEL; ERLOTINIB; ETOPOSIDE; GEFITINIB; IRINOTECAN; PACLITAXEL; PEMETREXED;

EID: 84869441859     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2012.43.1866     Document Type: Editorial
Times cited : (6)

References (44)
  • 1
    • 84869430260 scopus 로고    scopus 로고
    • Incorporating bevacizumab and erlotinib in the combined-modality treatment of stage III non-small-cell lung cancer: Results of a phase I/II trial
    • Socinski MA, Stinchcombe TE, Moore DT, et al: Incorporating bevacizumab and erlotinib in the combined-modality treatment of stage III non-small-cell lung cancer: Results of a phase I/II trial. J Clin Oncol 30:3953-3959, 2012
    • (2012) J Clin Oncol , vol.30 , pp. 3953-3959
    • Socinski, M.A.1    Stinchcombe, T.E.2    Moore, D.T.3
  • 2
    • 0029966671 scopus 로고    scopus 로고
    • Concurrent chemoradiation therapy with oral etoposide and cisplatin for locally advanced inoperable non-small-cell lung cancer: Radiation Therapy Oncology Group Protocol 91-06
    • Lee JS, Scott C, Komaki R, et al: Concurrent chemoradiation therapy with oral etoposide and cisplatin for locally advanced inoperable non-small-cell lung cancer: Radiation therapy oncology group protocol 91-06. J Clin Oncol 14:1055-1064, 1996 (Pubitemid 26105509)
    • (1996) Journal of Clinical Oncology , vol.14 , Issue.4 , pp. 1055-1064
    • Lee, J.S.1    Scott, C.2    Komaki, R.3    Fossella, F.V.4    Dundas, G.S.5    McDonald, S.6    Byhardt, R.W.7    Curran Jr., W.J.8
  • 5
    • 0031848532 scopus 로고    scopus 로고
    • Phase II trial of weekly paclitaxel and concurrent radiation therapy for locally advanced non-small cell lung cancer
    • Choy H, Safran H, Akerley W, et al: Phase II trial of weekly paclitaxel and concurrent radiation therapy for locally advanced non-small cell lung cancer. Clin Cancer Res 4:1931-1936, 1998 (Pubitemid 28369177)
    • (1998) Clinical Cancer Research , vol.4 , Issue.8 , pp. 1931-1936
    • Choy, H.1    Safran, H.2    Akerley, W.3    Graziano, S.L.4    Bogart, J.A.5    Cole, B.F.6
  • 6
    • 0032858243 scopus 로고    scopus 로고
    • Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vindesine, and cisplatin in unresectable stage III non-small-cell lung cancer
    • Furuse K, Fukuoka M, Kawahara M, et al: Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vindesine and cisplatin in unresectable stage III non-small cell lung cancer (NSCLC). J Clin Oncol 17:2692-2699, 1999 (Pubitemid 29415225)
    • (1999) Journal of Clinical Oncology , vol.17 , Issue.9 , pp. 2692-2699
    • Furuse, K.1    Fukuoka, M.2    Kawahara, M.3    Nishikawa, H.4    Takada, Y.5    Kudoh, S.6    Katagami, N.7    Ariyoshi, Y.8
  • 7
    • 80054072961 scopus 로고    scopus 로고
    • Sequential vs concurrent chemoradiation for stage III non-small cell lung cancer: Randomized phase III trial RTOG 9410
    • Curran WJ Jr, Paulus R, Langer CJ, et al: Sequential vs concurrent chemoradiation for stage III non-small cell lung cancer: Randomized phase III trial RTOG 9410. J Natl Cancer Inst 103:1452-1460, 2011
    • (2011) J Natl Cancer Inst , vol.103 , pp. 1452-1460
    • Curran Jr., W.J.1    Paulus, R.2    Langer, C.J.3
  • 10
    • 84862802175 scopus 로고    scopus 로고
    • Randomized phase II study of concurrent cisplatin/etoposide or paclitaxel/carboplatin and thoracic radiotherapy in patients with stage III non-small cell lung cancer
    • epub ahead of print on March 12
    • Wang L, Wu S, Ou G, et al: Randomized phase II study of concurrent cisplatin/etoposide or paclitaxel/carboplatin and thoracic radiotherapy in patients with stage III non-small cell lung cancer. Lung Cancer [epub ahead of print on March 12, 2012]
    • (2012) Lung Cancer
    • Wang, L.1    Wu, S.2    Ou, G.3
  • 11
    • 77957287051 scopus 로고    scopus 로고
    • Phase III study comparing second- And third-generation regimens with concurrent thoracic radiotherapy in patients with unresectable stage III non-small-cell lung cancer: West Japan Thoracic Oncology Group WJTOG0105
    • Yamamoto N, Nakagawa K, Nishimura Y, et al: Phase III study comparing second- and third-generation regimens with concurrent thoracic radiotherapy in patients with unresectable stage III non-small-cell lung cancer: West Japan Thoracic Oncology Group WJTOG0105. J Clin Oncol 28:3739-3745, 2010
    • (2010) J Clin Oncol , vol.28 , pp. 3739-3745
    • Yamamoto, N.1    Nakagawa, K.2    Nishimura, Y.3
  • 12
    • 80051742422 scopus 로고    scopus 로고
    • Randomized phase II study of pemetrexed, carboplatin, and thoracic radiation with or without cetuximab in patients with locally advanced unresectable non-small-cell lung cancer: Cancer and Leukemia Group B trial 30407
    • Govindan R, Bogart J, Stinchcombe T, et al: Randomized phase II study of pemetrexed, carboplatin, and thoracic radiation with or without cetuximab in patients with locally advanced unresectable non-small-cell lung cancer: Cancer and Leukemia Group B trial 30407. J Clin Oncol 29:3120-3125, 2011
    • (2011) J Clin Oncol , vol.29 , pp. 3120-3125
    • Govindan, R.1    Bogart, J.2    Stinchcombe, T.3
  • 13
    • 20544435485 scopus 로고    scopus 로고
    • Phase III study of the Eastern Cooperative Oncology Group (ECOG 2597): Induction chemotherapy followed by either standard thoracic radiotherapy or hyperfractionated accelerated radiotherapy for patients with unresectable stage IIIA and B non-small-cell lung cancer
    • Belani CP, Wang W, Johnson DH, et al: Phase III study of the Eastern Cooperative Oncology Group (ECOG 2597): Induction chemotherapy followed by either standard thoracic radiotherapy or hyperfractionated accelerated radiotherapy for patients with unresectable stage IIIA and B non-small-cell lung cancer. J Clin Oncol 23:3760-3767, 2005
    • (2005) J Clin Oncol , vol.23 , pp. 3760-3767
    • Belani, C.P.1    Wang, W.2    Johnson, D.H.3
  • 14
    • 34248651350 scopus 로고    scopus 로고
    • Induction chemotherapy followed by chemoradiotherapy compared with chemoradiotherapy alone for regionally advanced unresectable stage III non-small-cell lung cancer: Cancer and Leukemia Group B
    • Vokes EE, Herndon JE 2nd, Kelley MJ, et al: Induction chemotherapy followed by chemoradiotherapy compared with chemoradiotherapy alone for regionally advanced unresectable stage III non-small-cell lung cancer: Cancer and Leukemia Group B. J Clin Oncol 25:1698-1705, 2007
    • (2007) J Clin Oncol , vol.25 , pp. 1698-1705
    • Vokes, E.E.1    Herndon II, J.E.2    Kelley, M.J.3
  • 15
    • 57449090435 scopus 로고    scopus 로고
    • Phase III study of cisplatin, etoposide, and concurrent chest radiation with or without consolidation docetaxel in patients with inoperable stage III non-small-cell lung cancer: The Hoosier Oncology Group and US Oncology
    • Hanna N, Neubauer M, Yiannoutsos C, et al: Phase III study of cisplatin, etoposide, and concurrent chest radiation with or without consolidation docetaxel in patients with inoperable stage III non-small-cell lung cancer: The Hoosier Oncology Group and US Oncology. J Clin Oncol 26:5755-5760, 2008
    • (2008) J Clin Oncol , vol.26 , pp. 5755-5760
    • Hanna, N.1    Neubauer, M.2    Yiannoutsos, C.3
  • 16
    • 37649016872 scopus 로고    scopus 로고
    • Involved-field radiation therapy for inoperable non small-cell lung cancer
    • Rosenzweig KE, Sura S, Jackson A, et al: Involved-field radiation therapy for inoperable non small-cell lung cancer. J Clin Oncol 25:5557-5561, 2007
    • (2007) J Clin Oncol , vol.25 , pp. 5557-5561
    • Rosenzweig, K.E.1    Sura, S.2    Jackson, A.3
  • 17
    • 62349127678 scopus 로고    scopus 로고
    • Exclusion of elective nodal irradiation is associated with minimal elective nodal failure in non-small cell lung cancer
    • Sulman EP, Komaki R, Klopp AH, et al: Exclusion of elective nodal irradiation is associated with minimal elective nodal failure in non-small cell lung cancer. Radiat Oncol 4:5, 2009
    • (2009) Radiat Oncol , vol.4 , pp. 5
    • Sulman, E.P.1    Komaki, R.2    Klopp, A.H.3
  • 18
    • 18144374552 scopus 로고    scopus 로고
    • Does more aggressive therapy improve outcomes in the treatment of unresectable stage III non-small cell lung cancer?
    • Rosenman JG, Socinski MA: Does more aggressive therapy improve outcomes in the treatment of unresectable stage III non-small cell lung cancer? Semin Oncol 32:S13-S17, 2005 (suppl 3)
    • (2005) Semin Oncol , vol.32 , Issue.SUPPL. 3
    • Rosenman, J.G.1    Socinski, M.A.2
  • 19
    • 43249088259 scopus 로고    scopus 로고
    • Induction chemotherapy with carboplatin, irinotecan, and paclitaxel followed by high dose three-dimension conformal thoracic radiotherapy (74 Gy) with concurrent carboplatin, paclitaxel, and gefitinib in unresectable stage IIIA and stage IIIB non-small cell lung cancer
    • DOI 10.1097/JTO.0b013e3181653cf4, PII 0124389420080300000009
    • Stinchcombe TE, Morris DE, Lee CB, et al: Induction chemotherapy with carboplatin, irinotecan, and paclitaxel followed by high dose three-dimension conformal thoracic radiotherapy (74 Gy) with concurrent carboplatin, paclitaxel, and gefitinib in unresectable stage IIIA and stage IIIB non-small cell lung cancer. J Thorac Oncol 3:250-257, 2008 (Pubitemid 351654324)
    • (2008) Journal of Thoracic Oncology , vol.3 , Issue.3 , pp. 250-257
    • Stinchcombe, T.E.1    Morris, D.E.2    Lee, C.B.3    Moore, D.T.4    Hayes, D.N.5    Halle, J.S.6    Rivera, M.P.7    Rosenman, J.G.8    Socinski, M.A.9
  • 20
    • 69549088130 scopus 로고    scopus 로고
    • Treatment outcomes of different prognostic groups of patients on Cancer and Leukemia Group B trial 39801: Induction chemotherapy followed by chemoradiotherapy compared with chemoradiotherapy alone for unresectable stage III non-small cell lung cancer
    • Stinchcombe TE, Hodgson L, Herndon JE 2nd, et al: Treatment outcomes of different prognostic groups of patients on Cancer and Leukemia Group B trial 39801: Induction chemotherapy followed by chemoradiotherapy compared with chemoradiotherapy alone for unresectable stage III non-small cell lung cancer. J Thorac Oncol 4:1117-1125, 2009
    • (2009) J Thorac Oncol , vol.4 , pp. 1117-1125
    • Stinchcombe, T.E.1    Hodgson, L.2    Herndon II, J.E.3
  • 21
    • 45149128875 scopus 로고    scopus 로고
    • Randomized phase II trial of induction chemotherapy followed by concurrent chemotherapy and dose-escalated thoracic conformal radiotherapy (74 Gy) in stage III non-small-cell lung cancer: CALGB 30105
    • Socinski MA, Blackstock AW, Bogart JA, et al: Randomized phase II trial of induction chemotherapy followed by concurrent chemotherapy and dose-escalated thoracic conformal radiotherapy (74 Gy) in stage III non-small-cell lung cancer: CALGB 30105. J Clin Oncol 26:2457-2463, 2008
    • (2008) J Clin Oncol , vol.26 , pp. 2457-2463
    • Socinski, M.A.1    Blackstock, A.W.2    Bogart, J.A.3
  • 22
    • 80255122687 scopus 로고    scopus 로고
    • Pulmonary toxicity in stage III non-small cell lung cancer patients treated with high-dose (74 Gy) 3-dimensional conformal thoracic radiotherapy and concurrent chemotherapy following induction chemotherapy: A secondary analysis of Cancer and Leukemia Group B (CALGB) trial 30105
    • Salama JK, Stinchcombe TE, Gu L, et al: Pulmonary toxicity in stage III non-small cell lung cancer patients treated with high-dose (74 Gy) 3-dimensional conformal thoracic radiotherapy and concurrent chemotherapy following induction chemotherapy: A secondary analysis of Cancer and Leukemia Group B (CALGB) trial 30105. Int J Radiat Oncol Biol Phys 81:e269-e274, 2011
    • (2011) Int J Radiat Oncol Biol Phys , vol.81
    • Salama, J.K.1    Stinchcombe, T.E.2    Gu, L.3
  • 23
    • 77952488310 scopus 로고    scopus 로고
    • Primary analysis of the phase II component of a phase I/II dose intensification study using three-dimensional conformal radiation therapy and concurrent chemotherapy for patients with inoperable non-small-cell lung cancer: RTOG 0117
    • Bradley JD, Bae K, Graham MV, et al: Primary analysis of the phase II component of a phase I/II dose intensification study using three-dimensional conformal radiation therapy and concurrent chemotherapy for patients with inoperable non-small-cell lung cancer: RTOG 0117. J Clin Oncol 28:2475-2480, 2010
    • (2010) J Clin Oncol , vol.28 , pp. 2475-2480
    • Bradley, J.D.1    Bae, K.2    Graham, M.V.3
  • 24
    • 84870824788 scopus 로고    scopus 로고
    • Randomized phase III comparison of standard-dose (60 Gy) versus high-dose (74 Gy) conformal chemoradiotherapy with or without cetuximab for stage IIIA/IIIB non-small cell lung cancer: Preliminary findings on radiation dose in RTOG 0617
    • abstr LBA2
    • Bradley JD, Paulus R, Komaki R, et al: Randomized phase III comparison of standard-dose (60 Gy) versus high-dose (74 Gy) conformal chemoradiotherapy with or without cetuximab for stage IIIA/IIIB non-small cell lung cancer: Preliminary findings on radiation dose in RTOG 0617. 53rd Annual American Society for Radiation Oncology Meeting, Miami Beach, FL, October 2-6, 2011 (abstr LBA2)
    • 53rd Annual American Society for Radiation Oncology Meeting, Miami Beach, FL, October 2-6, 2011
    • Bradley, J.D.1    Paulus, R.2    Komaki, R.3
  • 27
    • 34250711876 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma
    • DOI 10.1158/1535-7163.MCT-07-0138
    • Frederick BA, Helfrich BA, Coldren CD, et al: Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma. Mol Cancer Ther 6:1683-1691, 2007 (Pubitemid 46954044)
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.6 , pp. 1683-1691
    • Frederick, B.A.1    Helfrich, B.A.2    Coldren, C.D.3    Zheng, D.4    Chan, D.5    Bunn Jr., P.A.6    Raben, D.7
  • 29
    • 63549083115 scopus 로고    scopus 로고
    • ErbB-3 expression is associated with E-cadherin and their co-expression restores response to gefitinib in nonsmall- Cell lung cancer (NSCLC)
    • Witta SE, Dziadziuszko R, Yoshida K, et al: ErbB-3 expression is associated with E-cadherin and their co-expression restores response to gefitinib in nonsmall- cell lung cancer (NSCLC). Ann Oncol 20:689-695, 2009
    • (2009) Ann Oncol , vol.20 , pp. 689-695
    • Witta, S.E.1    Dziadziuszko, R.2    Yoshida, K.3
  • 31
    • 79251603976 scopus 로고    scopus 로고
    • Gefitinib in combination with irradiation with or without cisplatin in patients with inoperable stage III non-small cell lung cancer: A phase I trial
    • Rothschild S, Bucher SE, Bernier J, et al: Gefitinib in combination with irradiation with or without cisplatin in patients with inoperable stage III non-small cell lung cancer: A phase I trial. Int J Radiat Oncol Biol Phys 80:126-132, 2011
    • (2011) Int J Radiat Oncol Biol Phys , vol.80 , pp. 126-132
    • Rothschild, S.1    Bucher, S.E.2    Bernier, J.3
  • 32
    • 77956267159 scopus 로고    scopus 로고
    • Chemoradiotherapy and gefitinib in stage III non-small cell lung cancer with epidermal growth factor receptor and KRAS mutation analysis: Cancer and Leukemia Group B (CALGB) 30106, a CALGB-stratified phase II trial
    • Ready N, Jänne PA, Bogart J, et al: Chemoradiotherapy and gefitinib in stage III non-small cell lung cancer with epidermal growth factor receptor and KRAS mutation analysis: Cancer and Leukemia Group B (CALGB) 30106, a CALGB-stratified phase II trial. J Thorac Oncol 5:1382-1390, 2010
    • (2010) J Thorac Oncol , vol.5 , pp. 1382-1390
    • Ready, N.1    Jänne, P.A.2    Bogart, J.3
  • 33
    • 76149123903 scopus 로고    scopus 로고
    • A phase I study of gefitinib with concurrent dose-escalated weekly docetaxel and conformal three-dimensional thoracic radiation followed by consolidative docetaxel and maintenance gefitinib for patients with stage iii non-small cell lung cancer
    • Center B, Petty WJ, Ayala D, et al: A phase I study of gefitinib with concurrent dose-escalated weekly docetaxel and conformal three-dimensional thoracic radiation followed by consolidative docetaxel and maintenance gefitinib for patients with stage iii non-small cell lung cancer. J Thorac Oncol 5:69-74, 2010
    • (2010) J Thorac Oncol , vol.5 , pp. 69-74
    • Center, B.1    Petty, W.J.2    Ayala, D.3
  • 34
    • 45149102984 scopus 로고    scopus 로고
    • Phase III trial of maintenance gefitinib or placebo after concurrent chemoradiotherapy and docetaxel consolidation in inoperable stage III non-small-cell lung cancer: SWOG S0023
    • Kelly K, Chansky K, Gaspar LE, et al: Phase III trial of maintenance gefitinib or placebo after concurrent chemoradiotherapy and docetaxel consolidation in inoperable stage III non-small-cell lung cancer: SWOG S0023. J Clin Oncol 26:2450-2456, 2008
    • (2008) J Clin Oncol , vol.26 , pp. 2450-2456
    • Kelly, K.1    Chansky, K.2    Gaspar, L.E.3
  • 35
    • 79960055286 scopus 로고    scopus 로고
    • Upfront gefitinib/erlotinib treatment followed by concomitant radiotherapy for advanced lung cancer: A monoinstitutional experience
    • Chang CC, Chi KH, Kao SJ, et al: Upfront gefitinib/erlotinib treatment followed by concomitant radiotherapy for advanced lung cancer: A monoinstitutional experience. Lung Cancer 73:189-194, 2011
    • (2011) Lung Cancer , vol.73 , pp. 189-194
    • Chang, C.C.1    Chi, K.H.2    Kao, S.J.3
  • 36
    • 11144223542 scopus 로고    scopus 로고
    • ZD6474, a potent inhibitor of vascular endothelial growth factor signaling, combined with radiotherapy: Schedule-dependent enhancement of antitumor activity
    • DOI 10.1158/1078-0432.CCR-04-1147
    • Williams KJ, Telfer BA, Brave S, et al: ZD6474, a potent inhibitor of vascular endothelial growth factor signaling, combined with radiotherapy: Schedule-dependent enhancement of antitumor activity. Clin Cancer Res 10:8587-8593, 2004 (Pubitemid 40053426)
    • (2004) Clinical Cancer Research , vol.10 , Issue.24 , pp. 8587-8593
    • Williams, K.J.1    Telfer, B.A.2    Brave, S.3    Kendrew, J.4    Whittaker, L.5    Stratford, I.J.6    Wedge, S.R.7
  • 38
    • 84858848994 scopus 로고    scopus 로고
    • Meta-analysis of randomized controlled trials for the incidence and risk of treatment-related mortality in patients with cancer treated with vascular endothelial growth factor tyrosine kinase inhibitors
    • Schutz FA, Je Y, Richards CJ, et al: Meta-analysis of randomized controlled trials for the incidence and risk of treatment-related mortality in patients with cancer treated with vascular endothelial growth factor tyrosine kinase inhibitors. J Clin Oncol 30:871-877, 2012
    • (2012) J Clin Oncol , vol.30 , pp. 871-877
    • Schutz, F.A.1    Je, Y.2    Richards, C.J.3
  • 39
    • 84859851347 scopus 로고    scopus 로고
    • Carboplatin and paclitaxel with vs without bevacizumab in older patients with advanced non-small cell lung cancer
    • Zhu J, Sharma DB, Gray SW, et al: Carboplatin and paclitaxel with vs without bevacizumab in older patients with advanced non-small cell lung cancer. JAMA 307:1593-1601, 2012
    • (2012) JAMA , vol.307 , pp. 1593-1601
    • Zhu, J.1    Sharma, D.B.2    Gray, S.W.3
  • 40
    • 74249123333 scopus 로고    scopus 로고
    • ALK gene rearrangements: A new therapeutic target in a molecularly defined subset of non-small cell lung cancer
    • Solomon B, Varella-Garcia M, Camidge DR: ALK gene rearrangements: A new therapeutic target in a molecularly defined subset of non-small cell lung cancer. J Thorac Oncol 4:1450-1454, 2009
    • (2009) J Thorac Oncol , vol.4 , pp. 1450-1454
    • Solomon, B.1    Varella-Garcia, M.2    Camidge, D.R.3
  • 41
    • 80053386829 scopus 로고    scopus 로고
    • Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: A retrospective analysis
    • Shaw AT, Yeap BY, Solomon BJ, et al: Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: A retrospective analysis. Lancet Oncol 12:1004-1012, 2011
    • (2011) Lancet Oncol , vol.12 , pp. 1004-1012
    • Shaw, A.T.1    Yeap, B.Y.2    Solomon, B.J.3
  • 42
    • 79957857433 scopus 로고    scopus 로고
    • The BATTLE trial: Personalizing therapy for lung cancer
    • Kim ES, Herbst RS, Wistuba II, et al: The BATTLE trial: Personalizing therapy for lung cancer. Cancer Discov 1:44-53, 2011
    • (2011) Cancer Discov , vol.1 , pp. 44-53
    • Kim, E.S.1    Herbst, R.S.2    Wistuba, I.I.3
  • 43
    • 84859187259 scopus 로고    scopus 로고
    • Systematic identification of genomic markers of drug sensitivity in cancer cells
    • Garnett MJ, Edelman EJ, Heidorn SJ, et al: Systematic identification of genomic markers of drug sensitivity in cancer cells. Nature 483:570-575, 2012
    • (2012) Nature , vol.483 , pp. 570-575
    • Garnett, M.J.1    Edelman, E.J.2    Heidorn, S.J.3
  • 44
    • 84863892117 scopus 로고    scopus 로고
    • Randomized phase II trial of erlotinib alone or with carboplatin and paclitaxel in patients who were never or light former smokers with advanced lung adenocarcinoma: CALGB 30406 Trial
    • Janne PA, Wang X, Socinski MA, et al: Randomized phase II trial of erlotinib alone or with carboplatin and paclitaxel in patients who were never or light former smokers with advanced lung adenocarcinoma: CALGB 30406 Trial. J Clin Oncol 30:2063-2069, 2012
    • (2012) J Clin Oncol , vol.30 , pp. 2063-2069
    • Janne, P.A.1    Wang, X.2    Socinski, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.