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Volumn 16, Issue 11, 2012, Pages 1846-1853

Development of a practical synthesis of a functionalized pyrrolo[2,1-f][1,2,4]triazine nucleus

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-CANCER AGENTS; BUILDING BLOCKES; C-ALKYLATION; CYCLODEHYDRATION; DEPROTECTION; DEVELOPMENT ACTIVITY; FORMAMIDINES; FUNCTIONALIZED;

EID: 84869419653     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op300252n     Document Type: Article
Times cited : (17)

References (29)
  • 9
    • 0141490765 scopus 로고    scopus 로고
    • JP 08059611A 19960305 Heisei. For amination of pyrrole 4 to 5, see
    • Hamamoto, I. Jpn. Kokai Tokkyo Koho (1996), JP 08059611A 19960305 Heisei. For amination of pyrrole 4 to 5, see
    • (1996) Jpn. Kokai Tokkyo Koho
    • Hamamoto, I.1
  • 17
    • 0033593517 scopus 로고    scopus 로고
    • No literature reference was found for preparation of N -amino-2,3-pyrrole dicarboxylates. A few methods are reported to prepare N -alkyl-2,3-pyrrole dicarboxylates. For an approach utilizing dipolar cycloaddition, see
    • No literature reference was found for preparation of N -amino-2,3-pyrrole dicarboxylates. A few methods are reported to prepare N -alkyl-2,3-pyrrole dicarboxylates. For an approach utilizing dipolar cycloaddition, see: Katritzky, A. R.; Yao, J.; Bao, W.; Qi, W.; Steel, P. J. J. Org. Chem. 1999, 64, 346-350
    • (1999) J. Org. Chem. , vol.64 , pp. 346-350
    • Katritzky, A.R.1    Yao, J.2    Bao, W.3    Qi, W.4    Steel, P.J.5
  • 18
    • 0027459455 scopus 로고
    • For preparation from functionalized diazoacetates and enol ether, see
    • For preparation from functionalized diazoacetates and enol ether, see: Hoffmann, M. G.; Wenkert, E. Tetrahedron 1993, 49, 1057-1062
    • (1993) Tetrahedron , vol.49 , pp. 1057-1062
    • Hoffmann, M.G.1    Wenkert, E.2
  • 24
    • 0000757859 scopus 로고
    • It has been reported that protic solvents favored C-alkylation, and O-alkylated products were the major product in polar aprotic solvents for the alkyation of cyclopentan-1,3-diones. See
    • It has been reported that protic solvents favored C-alkylation, and O-alkylated products were the major product in polar aprotic solvents for the alkyation of cyclopentan-1,3-diones. See: Schick, H.; Schwarz, H.; Finger, A.; Schwarz, S. Tetrahedron 1982, 38, 1279-1283
    • (1982) Tetrahedron , vol.38 , pp. 1279-1283
    • Schick, H.1    Schwarz, H.2    Finger, A.3    Schwarz, S.4
  • 28
    • 0042244428 scopus 로고    scopus 로고
    • Reduction of an amide to the corresponding amine was reported to proceed faster and cleaner with the LAH·2THF complex in toluene than that with LAH in THF, see
    • Reduction of an amide to the corresponding amine was reported to proceed faster and cleaner with the LAH·2THF complex in toluene than that with LAH in THF, see: Watson, T. J.; Ayers, T. A.; Shah, N.; Wenstrup, D.; Webster, M.; Freund, D.; Horgan, S.; Carey, J. P. Org. Process Res. Dev. 2003, 7, 521-532
    • (2003) Org. Process Res. Dev. , vol.7 , pp. 521-532
    • Watson, T.J.1    Ayers, T.A.2    Shah, N.3    Wenstrup, D.4    Webster, M.5    Freund, D.6    Horgan, S.7    Carey, J.P.8
  • 29
    • 84870628414 scopus 로고    scopus 로고
    • Synlett 2012, 23, accepted
    • Mudryk, B.; Joshi, A. Synlett 2012, 23, accepted.
    • Mudryk, B.1    Joshi, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.