MicroRNAs and unusual small RNAs discovered in Kaposi's sarcoma-associated herpesvirus virions

Journal of Virology

Volumn 86, Issue 23, 2012, Pages 12717-12730

  Lin, Xianzhi ^a   Li, Xiaofan ^a   Liang, Deguang ^a   Lan, Ke ^a  

^a Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA;

ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCATION; GENE TRANSFER; GENETIC ASSOCIATION; HOST CELL; HUMAN HERPESVIRUS 8; IN SITU HYBRIDIZATION; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RNA ANALYSIS; SEQUENCE ANALYSIS; VIRION; VIRUS CELL INTERACTION; VIRUS IDENTIFICATION; VIRUS PARTICLE;

BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE, TUMOR; DNA PRIMERS; HERPESVIRUS 8, HUMAN; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; IN SITU HYBRIDIZATION; MICRORNAS; MICROSCOPY, ELECTRON; MOLECULAR SEQUENCE DATA; REGULATORY SEQUENCES, RIBONUCLEIC ACID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL UNTRANSLATED; VIRION;

DNA VIRUSES; HUMAN HERPESVIRUS 8;

EID: 84869216658     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01473-12     Document Type: Article

References (50)

1. Abend JR, Uldrick T, Ziegelbauer JM. 2010. Regulation of tumor necrosis factor-like weak inducer of apoptosis receptor protein (TWEAKR) expression by Kaposi's sarcoma-associated herpesvirus microRNA prevents TWEAK-induced apoptosis and inflammatory cytokine expression. J. Virol. 84, 12139-12151.
2. Amen MA, Griffiths A. 2011. Identification and expression analysis of herpes B virus-encoded small RNAs. J. Virol. 85, 7296-7311.
3. Audic S, Claverie JM. 1997. The significance of digital gene expression profiles. Genome Res. 7, 986-995.
4. Bechtel J, Grundhoff A, Ganem D. 2005. RNAs in the virion of Kaposi's sarcoma-associated herpesvirus. J. Virol. 79, 10138-10146.
5. Bechtel JT, Winant RC, Ganem D. 2005. Host and viral proteins in the virion of Kaposi's sarcoma-associated herpesvirus. J. Virol. 79, 4952-4964.
6. Bellare P, Ganem D. 2009. Regulation of KSHV lytic switch protein expression by a virus-encoded microRNA, an evolutionary adaptation that fine-tunes lytic reactivation. Cell Host Microbe 6, 570-575.
7. Bresnahan WA, Shenk T. 2000. A subset of viral transcripts packaged within human cytomegalovirus particles. Science 288, 2373-2376.
8. Cai X, et al. 2005. Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells. Proc. Natl. Acad. Sci. U. S. A. 102, 5570-5575.
9. Chandran B. 2010. Early events in Kaposi's sarcoma-associated herpesvirus infection of target cells. J. Virol. 84, 2188-2199.
10. Chung SW, Arnott JA, Yang Y, Wong PM. 2003. Presence of prepackaged mRNA in virions of DNA adenovirus. J. Biol. Chem. 278, 50635-50640.
11. Cliffe AR, Nash AA, Dutia BM. 2009. Selective uptake of small RNA molecules in the virion of murine gammaherpesvirus 68. J. Virol. 83, 2321-2326.
12. Cullen BR. 2010. Five questions about viruses and microRNAs. PLoS Pathog. 6, e1000787. doi, 10.1371/journal.ppat.1000787.
13. Gottwein E, Cullen BR. 2010. A human herpesvirus microRNA inhibits p21 expression and attenuates p21-mediated cell cycle arrest. J. Virol. 84, 5229-5237.
14. Greijer AE, Dekkers CA, Middeldorp JM. 2000. Human cytomegalovirus virions differentially incorporate viral and host cell RNA during the assembly process. J. Virol. 74, 9078-9082.
15. Grundhoff A, Sullivan CS, Ganem D. 2006. A combined computational and microarray-based approach identifies novel microRNAs encoded by human gamma-herpesviruses. RNA 12, 733-750.
16. Jochum S, Ruiss R, Moosmann A, Hammerschmidt W, Zeidler R. 2012. RNAs in Epstein-Barr virions control early steps of infection. Proc. Natl. Acad. Sci. U. S. A. 109, E1396-E1404.
17. Keene SE, Telesnitsky A. 2012. Cis-acting determinants of 7SL RNA packaging by HIV-1. J. Virol. 86, 7934-7942.
18. Lagos D, et al. 2010. miR-132 regulates antiviral innate immunity through suppression of the p300 transcriptional co-activator. Nat. Cell Biol. 12, 513-519.
19. Lei X, et al. 2010. Regulation of NF-kappaB inhibitor IkappaBalpha and viral replication by a KSHV microRNA. Nat. Cell Biol. 12, 193-199.
20. Leung AK, Sharp PA. 2006. Function and localization of microRNAs in mammalian cells. Cold Spring Harb. Symp. Quant. Biol. 71, 29-38.
21. Li Z, et al. 2009. Characterization of viral and human RNAs smaller than canonical MicroRNAs. J. Virol. 83, 12751-12758.
22. Liang D, et al. 2011. A human herpesvirus miRNA attenuates interferon signaling and contributes to maintenance of viral latency by targeting IKKepsilon. Cell Res. 21, 793-806.
23. Lin X, et al. 2011. miR-K12-7-5p encoded by Kaposi's sarcomaassociated herpesvirus stabilizes the latent state by targeting viral ORF50/ RTA. PLoS One 6, e16224. doi, 10.1371/journal.pone.0016224.
24. Lin YT, et al. 2010. Small RNA profiling reveals antisense transcription throughout the KSHV genome and novel small RNAs. RNA 16, 1540-1558.
25. Lu CC, et al. 2010. MicroRNAs encoded by Kaposi's sarcoma-associated herpesvirus regulate viral life cycle. EMBO Rep. 11, 784-790.
26. Lu F, Stedman W, Yousef M, Renne R, Lieberman PM. 2010. Epigenetic regulation of Kaposi's sarcoma-associated herpesvirus latency by virusencoded microRNAs that target Rta and the cellular Rbl2-DNMT pathway. J. Virol. 84, 2697-2706.
27. Lwoff A, Horne R, Tournier P. 1962. A system of viruses. Cold Spring Harb. Symp. Quant. Biol. 27, 51-55.
28. Meckes DG, Jr, Raab-Traub N. 2011. Microvesicles and viral infection. J. Virol. 85, 12844-12854.
29. Mesri EA, Cesarman E, Boshoff C. 2010. Kaposi's sarcoma and its associated herpesvirus. Nat. Rev. Cancer 10, 707-719.
30. Mettenleiter TC, Klupp BG, Granzow H. 2009. Herpesvirus assembly, an update. Virus Res. 143, 222-234.
31. Muriaux D, Mirro J, Harvin D, Rein A. 2001. RNA is a structural element in retrovirus particles. Proc. Natl. Acad. Sci. U. S. A. 98, 5246-5251.
32. Nachmani D, Stern-Ginossar N, Sarid R, Mandelboim O. 2009. Diverse herpesvirus microRNAs target the stress-induced immune ligand MICB to escape recognition by natural killer cells. Cell Host Microbe 5, 376-385.
33. Nakamura H, et al. 2003. Global changes in Kaposi's sarcoma-associated virus gene expression patterns following expression of a tetracyclineinducible Rta transactivator. J. Virol. 77, 4205-4220.
34. Nealon K, et al. 2001. Lytic replication of Kaposi's sarcoma-associated herpesvirus results in the formation of multiple capsid species, isolation and molecular characterization of A, B, and C capsids from a gammaherpesvirus. J. Virol. 75, 2866-2878.
35. Pfeffer S, et al. 2005. Identification of microRNAs of the herpesvirus family. Nat. Methods 2, 269-276.
36. Politz JC, Hogan EM, Pederson T. 2009. MicroRNAs with a nucleolar location. RNA 15, 1705-1715.
37. Prichard MN, et al. 1998. Identification of persistent RNA-DNA hybrid structures within the origin of replication of human cytomegalovirus. J. Virol. 72, 6997-7004.
38. Punj V, et al. 2010. Kaposi's sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 suppresses CXCR4 expression by upregulating miR-146a. Oncogene 29, 1835-1844.
39. Roizman B. 2000. Redefining virology. Science 288, 2327-2328.
40. Samols MA, Hu J, Skalsky RL, Renne R. 2005. Cloning and identification of a microRNA cluster within the latency-associated region of Kaposi's sarcoma-associated herpesvirus. J. Virol. 79, 9301-9305.
41. Sciortino MT, Suzuki M, Taddeo B, Roizman B. 2001. RNAs extracted from herpes simplex virus 1 virions, apparent selectivity of viral but not cellular RNAs packaged in virions. J. Virol. 75, 8105-8116.
42. Sciortino MT, Taddeo B, Poon AP, Mastino A, Roizman B. 2002. Of the three tegument proteins that package mRNA in herpes simplex virions, one (VP22) transports the mRNA to uninfected cells for expression prior to viral infection. Proc. Natl. Acad. Sci. U. S. A. 99, 8318-8323.
43. Suffert G, et al. 2011. Kaposi's sarcoma herpesvirus microRNAs target caspase 3 and regulate apoptosis. PLoS Pathog. 7, e1002405. doi, 10.1371/ journal.ppat.1002405.
44. Tsai YH, et al. 2009. The M type K15 protein of Kaposi's sarcomaassociated herpesvirus regulates microRNA expression via its SH2-binding motif to induce cell migration and invasion. J. Virol. 83, 622-632.
45. Umbach JL, Cullen BR. 2010. In-depth analysis of Kaposi's sarcomaassociated herpesvirus microRNA expression provides insights into the mammalian microRNA-processing machinery. J. Virol. 84, 695-703.
46. Vieira J, O'Hearn PM. 2004. Use of the red fluorescent protein as a marker of Kaposi's sarcoma-associated herpesvirus lytic gene expression. Virology 325, 225-240.
47. Wang SW, Aldovini A. 2002. RNA incorporation is critical for retroviral particle integrity after cell membrane assembly of Gag complexes. J. Virol. 76, 11853-11865.
48. Wu YH, et al. 2011. The manipulation of miRNA-gene regulatory networks by KSHV induces endothelial cell motility. Blood 118, 2896-2905.
49. Xing L, Tikoo SK. 2004. Viral RNAs detected in virions of porcine adenovirus type 3. Virology 321, 372-382.
50. Zhu FX, Chong JM, Wu L, Yuan Y. 2005. Virion proteins of Kaposi's sarcoma-associated herpesvirus. J. Virol. 79, 800-811.