The manipulation of miRNA-gene regulatory networks by KSHV induces endothelial cell motility

Blood

Volumn 118, Issue 10, 2011, Pages 2896-2905

  Wu, Yu Hsuan ^a   Hu, Tzu Fang ^a   Chen, Yu Chieh ^a   Tsai, Ya Ni ^a   Tsai, Yuan Hau ^a   Cheng, Cheng Chung ^b   Wang, Hsei Wei ^a,c  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^c TAIPEI CITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

LATENCY ASSOCIATED NUCLEAR ANTIGEN; MICRORNA;

ARTICLE; CELL MIGRATION; CELL MOTILITY; DOWN REGULATION; DOWNSTREAM PROCESSING; ENDOTHELIUM CELL; GENE EXPRESSION; GENE REGULATORY NETWORK; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 8; METASTASIS; PRIORITY JOURNAL; REGULATORY MECHANISM; UPREGULATION;

EID: 80052673140     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-01-330589     Document Type: Article

References (49)

1. Chang Y, Cesarman E, Pessin MS, et al. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science. 1994;266(5192):1865-1869.
2. Hengge UR, Ruzicka T, Tyring SK, et al. Update on Kaposi's sarcoma and other HHV8 associated diseases. Part 2: pathogenesis, Castleman's disease, and pleural effusion lymphoma. Lancet Infect Dis. 2002;2(6):344-352. (Pubitemid 34595974)
3. Hong YK, Foreman K, Shin JW, et al. Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma-associated herpesvirus. Nat Genet. 2004;36(7):683-685. (Pubitemid 38886627)
4. Wang HW, Trotter MW, Lagos D, et al. Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma. Nat Genet. 2004;36(7):687-693. (Pubitemid 38886628)
5. Gessain A, Duprez R. Spindle cells and their role in Kaposi's sarcoma. Int J Biochem Cell Biol. 2005;37(12):2457-2465. (Pubitemid 41400316)
6. Ascoli V, Lo CF, Torelli G, et al. Human herpesvirus 8-associated primary effusion lymphoma in HIV-patients: a clinicopidemiologic variant resembling classic Kaposi's sarcoma. Haematologica. 2002;87(4):339-343. (Pubitemid 34297538)
7. Dezube BJ, Zambela M, Sage DR, Wang JF, Fingeroth JD. Characterization of Kaposi sarcoma-associated herpesvirus/human herpesvirus-8 infection of human vascular endothelial cells: early events. Blood. 2002;100(3):888-896. (Pubitemid 34832614)
8. Krug LT, Pozharskaya VP, Yu Y, Inoue N, Offermann MK. Inhibition of infection and replication of human herpesvirus 8 in microvascular endothelial cells by alpha interferon and phosphonoformic acid. J Virol. 2004;78(15):8359-8371. (Pubitemid 38944320)
9. McAllister SC, Moses AV. Endothelial cell- and lymphocyte-based in vitro systems for understanding KSHV biology. Curr Top Microbiol Immunol. 2007;312:211-244. (Pubitemid 47400349)
10. Qian LW, Xie J, Ye F, Gao SJ. Kaposi's sarcoma-associated herpesvirus infection promotes invasion of primary human umbilical vein endothelial cells by inducing matrix metalloproteinases. J Virol. 2007;81(13):7001-7010. (Pubitemid 46986636)
11. Tsai YH, Wu MF, Wu YH, et al. The M type K15 protein of Kaposi's sarcoma-associated herpesvirus regulates microRNA expression via its SH2-binding motif to induce cell migration and invasion. J Virol. 2009;83(2):622-632.
12. Croce CM, Calin GA. miRNAs, cancer, and stem cell division. Cell. 2005;122(1):6-7. (Pubitemid 40977933)
13. Poliseno L, Tuccoli A, Mariani L, et al. MicroRNAs modulate the angiogenic properties of HUVECs. Blood. 2006;108(9):3068-3071.
14. Suárez Y, Fernandez-Hernando C, Pober JS, Sessa WC. Dicer dependent microRNAs regulate gene expression and functions in human endothelial cells. Circ Res. 2007;100(8):1164-1173. (Pubitemid 46684129)
15. O'Hara AJ, Chugh P, Wang L, et al. Pre-micro RNA signatures delineate stages of endothelial cell transformation in Kaposi sarcoma. PLoS Pathog. 2009;5(4):e1000389.
16. O'Hara AJ, Wang L, Dezube BJ, et al. Tumor suppressor microRNAs are underrepresented in primary effusion lymphoma and Kaposi sarcoma. Blood. 2009;113(23):5938-5941.
17. Punj V, Matta H, Schamus S, et al. Kaposi's sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 suppresses CXCR4 expression by upregulating miR-146a. Oncogene. 2010;29(12):1835-1844.
18. Ades EW, Candal FJ, Swerlick RA, et al. HMEC-1: establishment of an immortalized human microvascular endothelial cell line. J Invest Dermatol. 1992;99(6):683-690. (Pubitemid 23002027)
19. An FQ, Folarin HM, Compitello N, et al. Long-term-infected telomerase-immortalized endothelial cells: a model for Kaposi's sarcoma-associated herpesvirus latency in vitro and in vivo. J Virol. 2006;80(10):4833-4846.
20. Vieira J, O'Hearn PM. Use of the red fluorescent protein as a marker of Kaposi's sarcoma-associated herpesvirus lytic gene expression. Virology. 2004;325(2):225-240. (Pubitemid 38902789)
21. Lagos D, Trotter MW, Vart RJ, et al. Kaposi sarcoma herpesvirus-encoded vFLIP and vIRF1 regulate antigen presentation in lymphatic endothelial cells. Blood. 2007;109(4):1550-1558. (Pubitemid 46239588)
22. Chen C, Ridzon DA, Broomer AJ, et al. Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Res. 2005;33(20):e179.
23. Hansen A, Henderson S, Lagos D, et al. KSHV-encoded miRNAs target MAF to induce endothelial cell reprogramming. Genes Dev. 2010;24(2):195-205.
24. Harris MA, Clark J, Ireland A, et al. The Gene Ontology (GO) database and informatics resource. Nucleic Acids Res. 2004;32(database issue):D258-D261.
25. Zhang B, Kirov S, Snoddy J. WebGestalt: an integrated system for exploring gene sets in various biological contexts. Nucleic Acids Res. 2005;33(web server issue):W741-W748.
26. Heusschen R, van GM, Griffioen AW, Thijssen VL. MicroRNAs in the tumor endothelium: novel controls on the angioregulatory switchboard. Biochim Biophys Acta. 2010;1805(1):87-96.
27. Wang S, Olson EN. AngiomiRs-key regulators of angiogenesis. Curr Opin Genet Dev. 2009;19(3):205-211.
28. Lagos D, Pollara G, Henderson S, et al. miR-132 regulates antiviral innate immunity through suppression of the p300 transcriptional coactivator. Nat Cell Biol. 2010;12(5):513-519.
29. Sadler R, Wu L, Forghani B, et al. A complex translational program generates multiple novel proteins from the latently expressed kaposin (K12) locus of Kaposi's sarcoma-associated herpesvirus. J Virol. 1999;73(7):5722-5730. (Pubitemid 29274858)
30. Lim C, Sohn H, Gwack Y, Choe J. Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8) binds ATF4/CREB2 and inhibits its transcriptional activation activity. J Gen Virol. 2000;81(11):2645-2652.
31. Verma SC, Borah S, Robertson ES. Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus up-regulates transcription of human telomerase reverse transcriptase promoter through interaction with transcription factor Sp1. J Virol. 2004;78(19):10348-10359. (Pubitemid 39258360)
32. Di Leva G, Gasparini P, Piovan C, et al. MicroRNA cluster 221-222 and estrogen receptor alpha interactions in breast cancer. J Natl Cancer Inst. 2010;102(10):706-721.
33. Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB. Prediction of mammalian microRNA targets. Cell. 2003;115(7):787-798. (Pubitemid 38058492)
34. Dittmer J. The biology of the Ets1 proto-oncogene. Mol Cancer. 2003;2:29.
35. Qi C, Zhu YT, Hu L, Zhu YJ. Identification of Fat4 as a candidate tumor suppressor gene in breast cancers. Int J Cancer. 2009;124(4):793-798.
36. Urbich C, Kuehbacher A, Dimmeler S. Role of microRNAs in vascular diseases, inflammation, and angiogenesis. Cardiovasc Res. 2008;79(4):581-588.
37. Anand S, Majeti BK, Acevedo LM, et al. MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis. Nat Med. 2010;16(8):909-914.
38. Wei G, Srinivasan R, Cantemir-Stone CZ, et al. Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis. Blood. 2009;114(5):1123-1130.
39. Huang X, Brown C, Ni W, et al. Critical role for the Ets transcription factor ELF-1 in the development of tumor angiogenesis. Blood. 2006;107(8):3153-3160.
40. McCormick C, Ganem D. The kaposin B protein of KSHV activates the p38/MK2 pathway and stabilizes cytokine mRNAs. Science. 2005;307(5710):739-741. (Pubitemid 40194646)
41. Slaby O, Svoboda M, Fabian P, et al. Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer. Oncology. 2007;72(5-6):397-402. (Pubitemid 351238155)
42. Wang CJ, Stratmann J, Zhou ZG, Sun XF. Suppression of microRNA-31 increases sensitivity to 5-FU at an early stage, and affects cell migration and invasion in HCT-116 colon cancer cells. BMC Cancer. 2010;10:616.
43. Valastyan S, Reinhardt F, Benaich N, et al. A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell. 2009;137(6):1032- 1046.
44. Suárez Y, Wang C, Manes TD, Pober JS. Cutting edge: TNF-induced microRNAs regulate TNF-induced expression of E-selectin and intercellular adhesion molecule-1 on human endothelial cells: feedback control of inflammation. J Immunol. 2010;184(1):21-25.
45. Luo J, Lin J, Paranya G, Bischoff J. Angiostatin upregulates E-selectin in proliferating endothelial cells. Biochem Biophys Res Commun. 1998;245(3):906-911. (Pubitemid 28414016)
46. Tanoue T, Takeichi M. New insights into Fat cadherins. J Cell Sci. 2005;118(11):2347-2353. (Pubitemid 40873074)
47. Saburi S, Hester I, Fischer E, et al. Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease. Nat Genet. 2008;40(8):1010-1015.
48. Pedrioli DM, Karpanen T, Dabouras V, et al. miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo. Mol Cell Biol. 2010;30(14):3620-3634.
49. Hong YK, Detmar M. Prox1, master regulator of the lymphatic vasculature phenotype. Cell Tissue Res. 2003;314(1):85-92. (Pubitemid 37409915)