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Volumn 13, Issue 11, 2012, Pages 894-903

Influence of gonadotropin-releasing hormone agonist on the effect of chemotherapy upon ovarian cancer and the prevention of chemotherapy-induced ovarian damage: An experimental study with nu/nu athymic mice

Author keywords

Animal experiment; Cisplatin; Gonadotrophin releasing hormone; Ovarian cancer

Indexed keywords

CASPASE 3; CISPLATIN; EOSIN; HEMATOXYLIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KI 67 ANTIGEN; MUELLERIAN INHIBITING FACTOR; TRIPTORELIN;

EID: 84869180257     PISSN: 16731581     EISSN: 18621783     Source Type: Journal    
DOI: 10.1631/jzus.B1100369     Document Type: Article
Times cited : (6)

References (33)
  • 1
    • 0034186201 scopus 로고    scopus 로고
    • Luteinizing hormonereleasing hormone as an autocrine growth factor in es-2 ovarian cancer cell line
    • Arencibia, J.M., Schally, A.V., 2000. Luteinizing hormonereleasing hormone as an autocrine growth factor in ES-2 ovarian cancer cell line. Int. J. Oncol., 16(5):1009-1013.
    • (2000) Int. J. Oncol , vol.16 , Issue.5 , pp. 1009-1013
    • Arencibia, J.M.1    Schally, A.V.2
  • 2
    • 0033044188 scopus 로고    scopus 로고
    • Regulation of spontaneous and TNF/IFN-induced IL-6 expression in two human ovarian-carcinoma cell lines
    • DOI 10.1002/(SICI)1097-0215(19990719)82:2<244::AID-IJC15>3.0.CO;2-N
    • Asschert, J.G., Vellenga, E., Ruiters, M.H., de Vries, E.G., Asschert, J.G., Vellenga, E., Ruiters, M.H., 1999. Regulation of spontaneous and TNF/IFN-induced IL-6 expression in two human ovarian-carcinoma cell lines. Int. J. Cancer, 82(2):244-249. [doi:10.1002/(SICI)1097-0215 (19990719)82:2<244:: AID-IJC15>3.0.CO;2-N] (Pubitemid 29293784)
    • (1999) International Journal of Cancer , vol.82 , Issue.2 , pp. 244-249
    • Asschert, J.G.W.1    Vellenga, E.2    Ruiters, M.H.J.3    De Vries, E.G.E.4
  • 3
    • 0028049074 scopus 로고
    • The NF-κB transcription factor and cancer: High expression of NF-κB- and IκB-related proteins in tumor cell lines
    • DOI 10.1016/0006-2952(94)90448-0
    • Bours, V., Dejardin, E., Goujon-Letawe, F., Merville, M.P., Castronovo, V., 1994. The NF-κB transcription factor and cancer: high expression of NF-κB and IκB related proteins in tumor cell lines. Biochem. Pharmacol., 47(1):145-149. [doi:10.1016/0006-2952(94)90448-0] (Pubitemid 24045827)
    • (1994) Biochemical Pharmacology , vol.47 , Issue.1 , pp. 145-149
    • Bours, V.1    Dejardin, E.2    Goujon-Letawe, F.3    Merville, M.-P.4    Castronovo, V.5
  • 4
    • 0029869593 scopus 로고    scopus 로고
    • Selective activation of NF-κB by nerve growth factor through the neurotrophin receptor p75
    • Carter, B.D., Kaltschmidt, C., Kaltschmidt, B., Offenhäuser, N., Böhm-Matthaei, R., Baeuerle, P.A., Barde, Y.A., 1996. Selective activation of NF-κB by nerve growth factor through the neurotrophin receptor p75. Science, 272(5261):542-545. [doi:10.1126/science.272.5261.542] (Pubitemid 26138196)
    • (1996) Science , vol.272 , Issue.5261 , pp. 542-545
    • Carter, B.D.1    Kaltschmidt, C.2    Kaltschmidt, B.3    Offenhauser, N.4    Bohm-Matthaei, R.5    Baeuerle, P.A.6    Barde, Y.-A.7
  • 5
    • 18144400990 scopus 로고    scopus 로고
    • Acute depletion of murine primordial follicle reserve by gonadotropin-releasing hormone antagonists
    • DOI 10.1016/j.fertnstert.2004.12.030
    • Danforth, D.R., Arbogast, L.K., Friedman, C.I., 2005. Acute depletion of murine primordial follicle reserve by gonadotropin-releasing hormone antagonists. Fertil. Steril., 83(5):1333-1338. [doi:10.1016/j.fertnstert.2004. 12.030] (Pubitemid 40615801)
    • (2005) Fertility and Sterility , vol.83 , Issue.5 , pp. 1333-1338
    • Danforth, D.R.1    Arbogast, L.K.2    Friedman, C.I.3
  • 6
    • 0028235123 scopus 로고
    • The use of luteinizing hormone releasing hormone agonists and antagonists in gynaecological cancers
    • Emons, G., Schally, A.V., 1994. The use of luteinizing hormone-releasing ormone agonists and antagonists in gynecological cancers. Hum. Reprod., 9(7):1364-1379. (Pubitemid 24224014)
    • (1994) Human Reproduction , vol.9 , Issue.7 , pp. 1364-1379
    • Emons, G.1    Schally, A.V.2
  • 7
    • 0343238179 scopus 로고    scopus 로고
    • LHRH might act as a negative autocrine regulator of proliferation of human ovarian cancer
    • Emons, G., Weiss, S., Ortmann, O., Grundker, C., Schulz, K.D., 2000. Luteinizing hormone-releasing hormone (LHRH) might act as a negative autocrine regulator of proliferation of human ovarian cancer. Eur. J. Endocrinol., 142(6):665-670. [doi:10.1530/eje.0.1420665] (Pubitemid 30399500)
    • (2000) European Journal of Endocrinology , vol.142 , Issue.6 , pp. 665-670
    • Emons, G.1    Weiss, S.2    Ortmann, O.3    Grundker, C.4    Schulz, K.-D.5
  • 8
    • 10144237848 scopus 로고    scopus 로고
    • Luteinizing hormone-releasing hormone agonist triptorelin in combination with cytotoxic chemotherapy in patients with advanced ovarian carcinoma: A prospective double blind randomized trial
    • DOI 10.1002/(SICI)1097-0142(19961001)78:7<1452::AID-CNCR12>3.0. CO;2-Z
    • Emons, G., Ortmann, O., Teichert, H.M., Fassl, H., Löhrs, U., Kullander, S., Kauppila, A., Ayalon, D., Schally, A., Oberheuser, F., 1996. Luteinizing hormone-releasing hormone agonist triptorelin in combination with cytotoxic chemotherapy in patients with advanced ovarian carcinoma. A prospective double blind randomized trial. Decapeptyl Ovarian Cancer Study Group. Cancer, 78(7):1452-1460. [doi:10.1002/(SICI)1097-0142(19961 001)78:7<1452::AID-CNCR12>3.3.CO;2-5] (Pubitemid 26317866)
    • (1996) Cancer , vol.78 , Issue.7 , pp. 1452-1460
    • Emons, G.1    Ortmann, O.2    Teichert, H.-M.3    Fassl, H.4    Lohrs, U.5    Kullander, S.6    Kauppila, A.7    Ayalon, D.8    Schally, A.9    Oberheuser, F.10
  • 9
    • 0031888955 scopus 로고    scopus 로고
    • A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
    • DOI 10.1038/34112
    • Enari, M., Sakahira, H., Yokoyama, H., Okawa, K., Iwamatsu, A., Nagata, S., 1998. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature, 391(6662):43-50. [doi:10.1038/34112] (Pubitemid 28079208)
    • (1998) Nature , vol.391 , Issue.6662 , pp. 43-50
    • Enari, M.1    Sakahira, H.2    Yokoyama, H.3    Okawa, K.4    Iwamatsu, A.5    Nagata, S.6
  • 10
    • 0029799831 scopus 로고    scopus 로고
    • Neuroprotection by aspirin and sodium salicylate through blockade of NF- κB activation
    • DOI 10.1126/science.274.5291.1383
    • Grilli, M., Pizzi, M., Memo, M., Spano, P., 1996. Neuroprotection by aspirin and sodium salicylate through blockade of NF-κB activation. Science, 274(5291):1383-1385. [doi:10.1126/science.274.5291.1383] (Pubitemid 26391464)
    • (1996) Science , vol.274 , Issue.5291 , pp. 1383-1385
    • Grilli, M.1    Pizzi, M.2    Memo, M.3    Spano, P.4
  • 11
    • 0029999656 scopus 로고    scopus 로고
    • Bcl-2 down-regulates the activity of transcription factor NF-κB induced upon apoptosis
    • DOI 10.1083/jcb.134.1.13
    • Grimm, S., Bauer, M.K., Baeuerle, P.A., Schulze-Osthoff, K., 1996. Bcl-2 down-regulates the activity of transcription factor NF-κB induced upon apoptosis. J. Cell Biol., 134(1):13-23. [doi:10.1083/jcb.134.1.13] (Pubitemid 26231517)
    • (1996) Journal of Cell Biology , vol.134 , Issue.1 , pp. 13-23
    • Grimm, S.1    Bauer, M.K.A.2    Baeuerle, P.A.3    Schulze-Osthoff, K.4
  • 12
    • 0033756722 scopus 로고    scopus 로고
    • Luteinizing hormone-releasing hormone induces nuclear factor κb-activation and inhibits apoptosis in ovarian cancer cells
    • doi:10.1210/jc.85.10.3815
    • Gründker, C., Schulz, K., Günthert, A.R., Emons, G., 2000. Luteinizing hormone-releasing hormone induces nuclear factor κB-activation and inhibits apoptosis in ovarian cancer cells. J. Clin. Endocrinol. Metab., 85(10):3815-3820. [doi:10.1210/jc.85.10.3815]
    • (2000) J. Clin. Endocrinol. Metab , vol.85 , Issue.10 , pp. 3815-3820
    • Gründker, C.1    Schulz, K.2    Günthert, A.R.3    Emons, G.4
  • 13
    • 0036164170 scopus 로고    scopus 로고
    • Biology of the gonadotropin-releasing hormone system in gynecological cancers
    • Gründker, C., Günthert, A.R., Westphalen, S., Emons, G., 2002a. Biology of the GnRH system in human gynecological cancers. Eur. J. Endocrinol., 146(1):1-14. [doi:10.1530/eje.0.1460001] (Pubitemid 34126412)
    • (2002) European Journal of Endocrinology , vol.146 , Issue.1 , pp. 1-14
    • Grundker, C.1    Gunthert, A.R.2    Westphalen, S.3    Emons, G.4
  • 14
    • 0036965115 scopus 로고    scopus 로고
    • Expression of gonadotropin-releasing hormone II (GnRH-II) receptor in human endometrial and ovarian cancer cells and effects of GnRH-II on tumor cell proliferation
    • DOI 10.1210/jc.87.3.1427
    • Gründker, C., Günthert, A.R., Millar, R.P., Emons, G., 2002b. Expression of gonadotropin-releasing hormone II (GnRH-II) receptor in human endometrial and ovarian cancer cells and effects of GnRH-II on tumor cell proliferation. J. Clin. Endocrinol. Metab., 87(3):1427-1430. [doi:10.1210/jc.87.3.1427] (Pubitemid 36121120)
    • (2002) Journal of Clinical Endocrinology and Metabolism , vol.87 , Issue.3 , pp. 1427-1430
    • Grundker, C.1    Gunthert, A.R.2    Millar, R.P.3    Emons, G.4
  • 15
    • 0034487528 scopus 로고    scopus 로고
    • Autocrine role of gonadotropin-releasing hormone and its receptor in ovarian cancer cell growth
    • DOI 10.1385/ENDO:13:3:297
    • Kang, S.K., Cheng, K.W., Nathwani, P.S., Choi, K.C., Leung, P.C., 2000. Autocrine role of gonadotropin-releasing hormone and its receptor in ovarian cancer cell growth. Endocrine, 13(3):297-304. [doi:10.1385/ENDO:13:3:297] (Pubitemid 32108057)
    • (2000) Endocrine , vol.13 , Issue.3 , pp. 297-304
    • Kang, S.K.1    Cheng, K.W.2    Nathwani, P.S.3    Choi, K.-C.4    Leung, P.C.K.5
  • 16
    • 33646014459 scopus 로고    scopus 로고
    • Mechanism of gonadotropin releasing hormone (gnrh)-i and -ii-induced cell growth inhibition in ovarian cancer cells: Role of the gnrh-i receptor and protein kinase c pathway
    • doi:10. 1677/erc.1.01033
    • Kim, K.Y., Choi, K.C., Auersperg, N.K., Leung, P.C., 2006. Mechanism of gonadotropin releasing hormone (GnRH)-I and -II-induced cell growth inhibition in ovarian cancer cells: role of the GnRH-I receptor and protein kinase C pathway. Endocr. Relat. Cancer, 13(1):211-220. [doi:10. 1677/erc.1.01033]
    • (2006) Endocr. Relat. Cancer , vol.13 , Issue.1 , pp. 211-220
    • Kim, K.Y.1    Choi, K.C.2    Auersperg, N.K.3    Leung, P.C.4
  • 17
    • 0031732851 scopus 로고    scopus 로고
    • Evidence for tight coupling of gonadotropin-releasing hormone receptor to stimulated fas ligand expression in reproductive tract tumors: Possible mechanism for hormonal control of apoptotic cell death
    • DOI 10.1210/jc.83.2.427
    • Imai, A., Takagi, A., Horibe, S., Takagi, H., Tamaya, T., 1998. Evidence for tight coupling of gonadotropin-releasing hormone receptor to stimulated Fas ligand expression in reproductive tract tumors: possible mechanism for hormonal control of apoptotic cell death. J. Clin. Endocrinol. Metab., 83(2):427-431. [doi:10.1210/jc.83.2.427] (Pubitemid 28496517)
    • (1998) Journal of Clinical Endocrinology and Metabolism , vol.83 , Issue.2 , pp. 427-431
    • Imai, A.1    Takagi, A.2    Horibe, S.3    Takagi, H.4    Tamaya, T.5
  • 18
    • 0027962578 scopus 로고
    • Gonadotropin-releasing hormone receptor in gynecologic tumors: Frequent expression in adenocarcinoma histologic types
    • DOI 10.1002/1097-0142(19941101)74:9<2555::AID-CNCR2820740925>3.0. CO;2-X
    • Imai, A., Ohno, T., Iida, K., Fuseya, T., Furui, T., Tamaya, T., 1994. Gonadotropin-releasing hormone receptor in gynecologic tumors. Frequent expression in adenocarcinoma histologic types. Cancer, 74(9):2555-2561. [doi:10.1002/1097-0142(19941101)74:9<2555::AID-CNCR 2820740925>3.0.CO;2-X] (Pubitemid 24320862)
    • (1994) Cancer , vol.74 , Issue.9 , pp. 2555-2561
    • Imai, A.1    Ohno, T.2    Iida, K.3    Fuseya, T.4    Furui, T.5    Tamaya, T.6
  • 19
    • 0033810206 scopus 로고    scopus 로고
    • Direct ovarian effects and safety aspects of gnrh agonists and antagonists
    • doi:10.1093/humupd/6.5.505
    • Janssens, R.M., Brus, L., Cahill, D.J., Huirne, J.A., Schoemaker, J., Lambalk, C.B., 2000. Direct ovarian effects and safety aspects of GnRH agonists and antagonists. Hum. Reprod. Update, 6(5):505-518. [doi:10.1093/humupd/6.5.505]
    • (2000) Hum. Reprod. Update , vol.6 , Issue.5 , pp. 505-518
    • Janssens, R.M.1    Brus, L.2    Cahill, D.J.3    Huirne, J.A.4    Schoemaker, J.5    Lambalk, C.B.6
  • 21
    • 0032772302 scopus 로고    scopus 로고
    • Subclinical depletion of primordial follicular reserve in mice treated with cyclophosphamide: Clinical importance and proposed accurate investigative tool
    • DOI 10.1093/humrep/14.7.1903
    • Meirow, D., Lewis, H., Nugent, D., Epstein, M., 1999. Subclinical depletion of primordial follicular reserve in mice treated with cyclophosphamide: clinical importance and proposed accurate investigative tool. Hum. Reprod., 14(7):1903-1907. [doi:10.1093/humrep/14.7.1903] (Pubitemid 29358724)
    • (1999) Human Reproduction , vol.14 , Issue.7 , pp. 1903-1907
    • Meirow, D.1    Lewis, H.2    Nugent, D.3    Epstein, M.4
  • 22
    • 3042645545 scopus 로고    scopus 로고
    • The GnRh antagonist cetrorelix reduces cyclophosphamide-induced ovarian follicular destruction in mice
    • DOI 10.1093/humrep/deh257
    • Meirow, D., Assad, G., Dor, J., Rabinovici, J., 2004. The GnRH antagonist cetrorelix reduces cyclophosphamideinduced ovarian follicular destruction in mice. Hum. Reprod., 19(6):1294-1299. [doi:10.1093/humrep/deh257] (Pubitemid 38807699)
    • (2004) Human Reproduction , vol.19 , Issue.6 , pp. 1294-1299
    • Meirow, D.1    Assad, G.2    Dor, J.3    Rabinovici, J.4
  • 23
    • 2942542957 scopus 로고    scopus 로고
    • Methods for quantifying follicular numbers within the mouse ovary
    • Myers, M., Britt, K.L., Wreford, N.G., Ebling, F.J., Kerr, J.B., 2004. Methods for quantifying follicular numbers within the mouse ovary. Reproduction, 127(5):569-580. [doi:10.1530/rep.1.00095] (Pubitemid 38745074)
    • (2004) Reproduction , vol.127 , Issue.5 , pp. 569-580
    • Myers, M.1    Britt, K.L.2    Wreford, N.G.M.3    Ebling, F.J.P.4    Kerr, J.B.5
  • 24
    • 43049086657 scopus 로고    scopus 로고
    • Nuclear factor-κB1: Regulation and function
    • DOI 10.1016/j.biocel.2007.05.004, PII S1357272507001501
    • Pereira, S.G., Oakley, F., 2008. Nuclear factor-kappaB1: regulation and function. Int. J. Biochem. Cell Biol., 40(8):1425-1430. [doi:10.1016/j.biocel. 2007.05.004] (Pubitemid 351626701)
    • (2008) International Journal of Biochemistry and Cell Biology , vol.40 , Issue.8 , pp. 1425-1430
    • Pereira, S.G.1    Oakley, F.2
  • 25
    • 0032249062 scopus 로고    scopus 로고
    • Inhibitory effects of cytokines on ovarian and endometrial carcinoma cells in vitro with special reference to induction of specific transcriptional regulators
    • Seppänen, M., Henttinen, T., Lin, L., Punnonen, J., Grénman, S., Punnonen, R., Vihko, K.K., 1998. Inhibitory effects of cytokines on ovarian and endometrial carcinoma cells in vitro with special reference to induction of specific transcriptional regulators. Oncol. Res., 10(11-12):575-589. (Pubitemid 128740446)
    • (1998) Oncology Research , vol.10 , Issue.11-12 , pp. 575-589
    • Seppanen, M.1    Henttinen, T.2    Lin, L.3    Punnonen, J.4    Grenman, S.5    Punnonen, R.6    Vihko, K.K.7
  • 26
    • 0031214249 scopus 로고    scopus 로고
    • Involvement of annexin V in antiproliferative effects of gonadotropin- releasing hormone agonists on human endometrial cancer cell line
    • DOI 10.1006/gyno.1997.4746
    • Shibata, S., Sato, H., Ota, H., Karube, A., Takahashi, O., Tanaka, T., 1997. Involvement of annexin V in antiproliferative effects of gonadotropin-releasing hormone agonists on human endometrial cancer cell line. Gynecol. Oncol., 66(2):217-221. [doi:10.1006/gyno.1997.4746] (Pubitemid 27335406)
    • (1997) Gynecologic Oncology , vol.66 , Issue.2 , pp. 217-221
    • Shibata, S.1    Sato, H.2    Ota, H.3    Karube, A.4    Takahashi, O.5    Tanaka, T.6
  • 28
    • 34748855636 scopus 로고    scopus 로고
    • NFKB and NFKBI polymorphisms in relation to susceptibility of tumour and other diseases
    • Sun, X.F., Zhang, H., 2007. NF-κB and NF-κBI polymorphisms in relation to susceptibility of tumour and other diseases. Histol. Histopathol., 22(12):1387-1398. (Pubitemid 47470331)
    • (2007) Histology and Histopathology , vol.22 , Issue.10-12 , pp. 1387-1398
    • Sun, X.-F.1    Zhang, H.2
  • 30
    • 0036182849 scopus 로고    scopus 로고
    • Expression of receptors for luteinizing hormone-releasing hormone in human ovarian and endometrial cancers: Frequency, autoregulation, and correlation with direct antiproliferative activity of luteinizing hormone-releasing hormone analogues
    • DOI 10.1067/mob.2002.119633
    • Völker, P., Gründker, C., Schmidt, O., Schulz, K.D., Emons, G., 2002. Expression of receptors for luteinizing hormone-releasing hormone in human ovarian andendometrial cancers: frequency, autoregulation, and correlation with direct antiproliferative activity of luteinizing hormone-releasing hormone analogues. Am. J. Obstet. Gynecol., 186(2):171-179. [doi:10.1067/mob.2002. 119633] (Pubitemid 34165428)
    • (2002) American Journal of Obstetrics and Gynecology , vol.186 , Issue.2 , pp. 171-179
    • Volker, P.1    Grundker, C.2    Schmidt, O.3    Schulz, K.-D.4    Emons, G.5
  • 31
    • 0032508414 scopus 로고    scopus 로고
    • NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c- IAP2 to suppress caspase-8 activation
    • DOI 10.1126/science.281.5383.1680
    • Wang, C.Y., Mayo, M.W., Korneluk, R.G., Goeddel, D.V., Baldwin, A.S.Jr., 1998. NF-kappaB anti-apoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science, 281(5383): 1680-1683. [doi:10.1126/science.281.5383.1680] (Pubitemid 28435585)
    • (1998) Science , vol.281 , Issue.5383 , pp. 1680-1683
    • Wang, C.-Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin Jr., A.S.5
  • 33
    • 0030745646 scopus 로고    scopus 로고
    • Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
    • DOI 10.1016/S0092-8674(00)80501-2
    • Zou, H., Henzel, W.J., Liu, X., Lutschg, A., Wang, X., 1997. A human protein homologues to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell, 90(3):405-413. [doi:10.1016/S0092-8674(00)80501- 2] (Pubitemid 27347231)
    • (1997) Cell , vol.90 , Issue.3 , pp. 405-413
    • Zou, H.1    Henzel, W.J.2    Liu, X.3    Lutschg, A.4    Wang, X.5


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