Decreases in manganese superoxide dismutase expression and activity contribute to oxidative stress in persistent pulmonary hypertension of the newborn

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 303, Issue 10, 2012, Pages

  Afolayan, Adeleye J ^a   Eis, Annie ^a   Teng, Ru Jeng ^a   Bakhutashvili, Ivane ^a   Kaul, Sushma ^a   Davis, Jonathan M ^b   Konduri, Girija G ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b TUFTS MEDICAL CENTER   (United States)

Author keywords

Antioxidants; Catalase; Endothelial nitric oxide synthase; Gene transduction; Mitochondrial superoxide; Vasodilation

Indexed keywords

ADENOVIRUS VECTOR; CATALASE; HYDROGEN PEROXIDE; MANGANESE SUPEROXIDE DISMUTASE; MANGANESE SUPEROXIDE DISMUTASE ADENOVIRUS VECTOR; MITOCHONDRIAL ENZYME; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY ENDOTHELIUM; ARTICLE; BLOOD VESSEL REACTIVITY; CELL ISOLATION; CONTROLLED STUDY; DUCTUS ARTERIOSUS OBLITERATION; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVITY; GENETIC TRANSDUCTION; LAMB; NEWBORN; NITRATION; NONHUMAN; OXIDATIVE STRESS; PERSISTENT PULMONARY HYPERTENSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY ARTERY;

ADENOVIRIDAE; ANIMALS; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENETIC VECTORS; HUMANS; HYDROGEN PEROXIDE; INFANT, NEWBORN; MITOCHONDRIA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; PERSISTENT FETAL CIRCULATION SYNDROME; PULMONARY ARTERY; RNA, MESSENGER; SHEEP; SUPEROXIDE DISMUTASE; SUPEROXIDES; TRANSDUCTION, GENETIC; VASODILATION;

EID: 84869148621     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00098.2012     Document Type: Article

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