Neutralization of dengue virus in the presence of Fc receptor-mediated phagocytosis distinguishes serotype-specific from cross-neutralizing antibodies

Antiviral Research

Volumn 96, Issue 3, 2012, Pages 340-343

  Wu, Ryan S L ^a   Chan, Kuan Rong ^b   Tan, Hwee Cheng ^a   Chow, Angelia ^a   Allen, John C ^a   Ooi, Eng Eong ^a  

^a DUKE NUS MEDICAL SCHOOL   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Dengue virus; Fc R mediated phagocytosis; Immunity; Neutralization

Indexed keywords

FC RECEPTOR; NEUTRALIZING ANTIBODY;

ADULT; ARTICLE; DENGUE VIRUS; HUMAN; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; SEROTYPE; VIRUS ENTRY;

ADULT; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; CELL LINE, TUMOR; CROSS REACTIONS; DENGUE; DENGUE VIRUS; HOST-PATHOGEN INTERACTIONS; HUMANS; NEUTRALIZATION TESTS; PHAGOCYTOSIS; RECEPTORS, IGG; SENSITIVITY AND SPECIFICITY; SPECIES SPECIFICITY; VIRAL PLAQUE ASSAY; VIRUS INTERNALIZATION;

DENGUE VIRUS;

EID: 84869120222     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2012.09.018     Document Type: Article

References (15)

1. Beltramello M., Williams K.L., Simmons C.P., Macagno A., Simonelli L., Quyen N.T., Sukupolvi-Petty S., Navarro-Sanchez E., Young P.R., de Silva A.M., Rey F.A., Varani L., Whitehead S.S., Diamond M.S., Harris E., Lanzavecchia A., Sallusto F. The human immune response to dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity. Cell Host Microbe 2010, 8:271-283.
2. Chan K.R., Zhang S.L., Tan H.C., Chan Y.K., Chow A., Lim A.P., Vasudevan S.G., Hanson B.J., Ooi E.E. Ligation of Fc gamma receptor IIB inhibits antibody-dependent enhancement of dengue virus infection. Proc. Natl. Acad. Sci. USA 2011, 108:12479-12484.
3. de Alwis R., Beltramello M., Messer W.B., Sukupolvi-Petty S., Wahala W.M., Kraus A., Olivarez N.P., Pham Q., Brien J.D., Tsai W.Y., Wang W.K., Halstead S., Kliks S., Diamond M.S., Baric R., Lanzavecchia A., Sallusto F., de Silva A.M. In-depth analysis of the antibody response of individuals exposed to primary dengue virus infection. PLoS Negl. Trop. Dis. 2011, 5:e1188.
4. de Alwis R., Smith S.A., Olivarez N.P., Messer W.B., Huynh J.P., Wahala W.M., White L.J., Diamond M.S., Baric R.S., Crowe J.E., de Silva A.M. Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions. Proc. Natl. Acad. Sci. USA 2012, 109:7439-7444.
5. Dejnirattisai W., Jumnainsong A., Onsirisakul N., Fitton P., Vasanawathana S., Limpitikul W., Puttikhunt C., Edwards C., Duangchinda T., Supasa S., Chawansuntati K., Malasit P., Mongkolsapaya J., Screaton G. Cross-reacting antibodies enhance dengue virus infection in humans. Science 2010, 328:745-748.
6. Durbin A.P., Vargas M.J., Wanionek K., Hammond S.N., Gordon A., Rocha C., Balmaseda A., Harris E. Phenotyping of peripheral blood mononuclear cells during acute dengue illness demonstrates infection and increased activation of monocytes in severe cases compared to classic dengue fever. Virology 2008, 376:429-435.
7. Endy T.P., Nisalak A., Chunsuttitwat S., Vaughn D.W., Green S., Ennis F.A., Rothman A.L., Libraty D.H. Relationship of preexisting dengue virus (DV) neutralizing antibody levels to viremia and severity of disease in a prospective cohort study of DV infection in Thailand. J. Infect. Dis. 2004, 189:990-1000.
8. Halstead S.B. Pathogenesis of dengue: challenges to molecular biology. Science 1988, 239:476-481.
9. Low J.G., Ooi E.E., Tolfvenstam T., Leo Y.S., Hibberd M.L., Ng L.C., Lai Y.L., Yap G.S., Li C.S., Vasudevan S.G., Ong A. Early dengue infection and outcome study (EDEN) - study design and preliminary findings. Ann. Acad. Med. Singapore 2006, 35:783-789.
10. Pierson T.C., Xu Q., Nelson S., Oliphant T., Nybakken G.E., Fremont D.H., Diamond M.S. The stoichiometry of antibody-mediated neutralization and enhancement of West Nile virus infection. Cell Host Microbe 2007, 1:135-145.
11. Putnak J.R., de la Barrera R., Burgess T., Pardo J., Dessy F., Gheysen D., Lobet Y., Green S., Endy T.P., Thomas S.J., Eckels K.H., Innis B.L., Sun W. Comparative evaluation of three assays for measurement of dengue virus neutralizing antibodies. Am. J. Trop. Med. Hyg. 2008, 79:115-122.
12. Roehrig J.T., Hombach J., Barrett A.D. Guidelines for plaque-reduction neutralization testing of human antibodies to dengue viruses. Viral Immunol. 2008, 21:123-132.
13. Sabin A.B. Research on dengue during world war II. Am. J. Trop. Med. Hyg. 1952, 1:30-50.
14. Teoh E.P., Kukkaro P., Teo E.W., Lim A.P., Tan T.T., Yip A., Schul W., Aung M., Kostyuchenko V.A., Leo Y.S., Chan S.H., Smith K.G., Chan A.H., Zou G., Ooi E.E., Kemeny D.M., Tan G.K., Ng J.K., Ng M.L., Alonso S., Fisher D., Shi P.Y., Hanson B.J., Lok S.M., Macary P.A. The structural basis for serotype-specific neutralization of dengue virus by a human antibody. Science Translational Medicine 2012, 4:139ra183.
15. van der Schaar H.M., Rust M.J., Waarts B.L., van der Ende-Metselaar H., Kuhn R.J., Wilschut J., Zhuang X., Smit J.M. Characterization of the early events in dengue virus cell entry by biochemical assays and single-virus tracking. J. Virol. 2007, 81:12019-12028.