Plac8 is required for White Adipocyte Differentiation in vitro and Cell Number Control in vivo

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Jimenez Preitner, Maria ^a   Berney, Xavier ^a   Thorens, Bernard ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CCAAT ENHANCER BINDING PROTEIN BETA; FATTY ACID; GLUCOSE; KRUPPEL LIKE FACTOR 4; PROTEIN KROX20; TRANSCRIPTION FACTOR; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADIPOCYTE; ADIPOGENESIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CEBPBETA GENE; CELL COUNT; CELL DIFFERENTIATION; CONTROLLED STUDY; DYSLIPIDEMIA; EMBRYO; FATTY ACID BLOOD LEVEL; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE SILENCING; GLUCOSE BLOOD LEVEL; IN VITRO STUDY; IN VIVO STUDY; KLF4 GENE; KROX20 GENE; LIPID STORAGE; MALE; MOUSE; NONHUMAN; PLAC8 GENE; PROMOTER REGION; PROTEIN FUNCTION; REGULATOR GENE; REGULATORY MECHANISM; THERMOGENESIS; TRIACYLGLYCEROL BLOOD LEVEL; WHITE ADIPOSE TISSUE;

ADIPOCYTES, WHITE; ADIPOGENESIS; ANIMALS; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELL COUNT; CELL DIFFERENTIATION; MICE; MICE, KNOCKOUT; PROMOTER REGIONS, GENETIC; PROTEINS;

MUS;

EID: 84869106935     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048767     Document Type: Article

References (23)

1. Rosen ED, MacDougald OA, (2006) Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol 7: 885-896.
2. Farmer SR, (2006) Transcriptional control of adipocyte formation. Cell Metab 4: 263-273.
3. Wellen KE, Hotamisligil GS, (2005) Inflammation, stress, and diabetes. J Clin Invest 115: 1111-1119.
4. Virtue S, Vidal-Puig A, (2010) Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome-an allostatic perspective. Biochim Biophys Acta 1801: 338-349.
5. Lumeng CN, Saltiel AR, (2011) Inflammatory links between obesity and metabolic disease. J Clin Invest 121: 2111-2117.
6. Kajimura S, Seale P, Spiegelman BM, (2010) Transcriptional control of brown fat development. Cell Metab 11: 257-262.
7. Birsoy K, Chen Z, Friedman J, (2008) Transcriptional regulation of adipogenesis by KLF4. Cell Metab 7: 339-347.
8. Chen Z, Torrens JI, Anand A, Spiegelman BM, Friedman JM, (2005) Krox20 stimulates adipogenesis via C/EBPbeta-dependent and-independent mechanisms. Cell Metab 1: 93-106.
9. Tanaka T, Yoshida N, Kishimoto T, Akira S, (1997) Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene. Embo J 16: 7432-7443.
10. Libault M, Stacey G, (2010) Evolution of FW2.2-like (FWL) and PLAC8 genes in eukaryotes. Plant Signal Behav 5.
11. Jimenez-Preitner M, Berney X, Uldry M, Vitali A, Cinti S, et al. (2011) Plac8 is an inducer of C/EBPbeta required for brown fat differentiation, thermoregulation, and control of body weight. Cell Metab 14: 658-670.
12. Ledford JG, Kovarova M, Koller BH, (2007) Impaired host defense in mice lacking ONZIN. J Immunol 178: 5132-5143.
13. Jimenez M, Yvon C, Lehr L, Leger B, Keller P, et al. (2002) Expression of uncoupling protein-3 in subsarcolemmal and intermyofibrillar mitochondria of various mouse muscle types and its modulation by fasting. Eur J Biochem 269: 2878-2884.
14. Jordan M, Schallhorn A, Wurm FM, (1996) Transfecting mammalian cells: optimization of critical parameters affecting calcium-phosphate precipitate formation. NuclAcids Res 24: 596-601.
15. Daxhelet GA, Coene MM, Hoet PP, Cocito CG, (1989) Spectrofluorometry of dyes with DNAs of different base composition and conformation. Anal Biochem 179: 401-403.
16. Rogulski K, Li Y, Rothermund K, Pu L, Watkins S, et al. (2005) Onzin, a c-Myc-repressed target, promotes survival and transformation by modulating the Akt-Mdm2-p53 pathway. Oncogene 24: 7524-7541.
17. Li Y, Rogulski K, Zhou Q, Sims PJ, Prochownik EV, (2006) The negative c-Myc target onzin affects proliferation and apoptosis via its obligate interaction with phospholipid scramblase 1. Mol Cell Biol 26: 3401-3413.
18. Zhang JW, Klemm DJ, Vinson C, Lane MD, (2004) Role of CREB in transcriptional regulation of CCAAT/enhancer-binding protein beta gene during adipogenesis. J Biol Chem 279: 4471-4478.
19. Mori T, Sakaue H, Iguchi H, Gomi H, Okada Y, et al. (2005) Role of Kruppel-like factor 15 (KLF15) in transcriptional regulation of adipogenesis. J Biol Chem 280: 12867-12875.
20. Fisch S, Gray S, Heymans S, Haldar SM, Wang B, et al. (2007) Kruppel-like factor 15 is a regulator of cardiomyocyte hypertrophy. Proc Natl Acad Sci U S A 104: 7074-7079.
21. Lemonnier D, (1972) Effect of age, sex, and sites on the cellularity of the adipose tissue in mice and rats rendered obese by a high-fat diet. J Clin Invest 51: 2907-2915.
22. Bertrand HA, Stacy C, Masoro EJ, Yu BP, Murata I, et al. (1984) Plasticity of fat cell number. J Nutr 114: 127-131.
23. Prunet-Marcassus B, Cousin B, Caton D, Andre M, Penicaud L, et al. (2006) From heterogeneity to plasticity in adipose tissues: site-specific differences. Exp Cell Res 312: 727-736.