A trapper keeper for TRAPP, its structures and functions

Cellular and Molecular Life Sciences

Volumn 69, Issue 23, 2012, Pages 3933-3944

  Yu, Sidney ^a   Liang, Yongheng ^b  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b NANJING AGRICULTURAL UNIVERSITY   (China)

Author keywords

Autophagy; COPII vesicle; ER exit sites; TRAPP; Vesicular transport

Indexed keywords

COAT PROTEIN COMPLEX II; MULTIPROTEIN COMPLEX; RAB11 PROTEIN; REV PROTEIN; TRANSPORT PROTEIN PARTICLE COMPLEX; TRANSPORT PROTEIN PARTICLE COMPLEX 1; TRANSPORT PROTEIN PARTICLE COMPLEX 10; TRANSPORT PROTEIN PARTICLE COMPLEX 2; TRANSPORT PROTEIN PARTICLE COMPLEX 3; TRANSPORT PROTEIN PARTICLE COMPLEX 4; TRANSPORT PROTEIN PARTICLE COMPLEX 5; TRANSPORT PROTEIN PARTICLE COMPLEX 6; TRANSPORT PROTEIN PARTICLE COMPLEX 7; TRANSPORT PROTEIN PARTICLE COMPLEX 8; TRANSPORT PROTEIN PARTICLE COMPLEX 9; UNCLASSIFIED DRUG; PROTEIN BINDING; TRANSPORT PROTEIN PARTICLE, TRAPP; VESICULAR TRANSPORT PROTEIN;

AUTOPHAGY; BIOGENESIS; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; CILIOGENESIS; CYTOKINESIS; ENDOPLASMIC RETICULUM; GENETIC DISORDER; HUMAN; INTELLECTUAL IMPAIRMENT; MELANOSOME; MICROTUBULE ASSEMBLY; MOLECULAR BIOLOGY; MOLECULAR DYNAMICS; MOLECULAR WEIGHT; NONHUMAN; PIGMENTATION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW; X LINKED SPONDYLOEPIPHYSEAL DYSPLASIA TARDA; YEAST; ANIMAL; BIOLOGICAL MODEL; CELL MEMBRANE; COP-COATED VESICLE; GOLGI COMPLEX; METABOLISM; PROTEIN TRANSPORT;

ANIMALS; CELL MEMBRANE; COP-COATED VESICLES; ENDOPLASMIC RETICULUM; GOLGI APPARATUS; HUMANS; MODELS, BIOLOGICAL; PROTEIN BINDING; PROTEIN TRANSPORT; VESICULAR TRANSPORT PROTEINS;

EID: 84869087678     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-012-1024-3     Document Type: Review

References (92)

1. Whyte JRC, Munro S (2002) Vesicle tethering complexes in membrane traffic. J Cell Sci 115:2627-2637
2. Sacher M, Barrowman J, Wang W, Horecka J, Zhang Y et al (2001) TRAPP I implicated in the specificity of tethering in ERto-Golgi transport. Mol Cell 7:433-442
3. Lord C, Bhandari D, Menon S, Ghassemian M, Nycz D et al (2011) Sequential interactions with Sec23 control the direction of vesicle traffic. Nature 473:181-186
4. Kim Y-G, Raunser S, Munger C, Wagner J, Song Y-L et al (2006) The architecture of the multisubunit TRAPP I complex suggests a model for vesicle tethering. Cell 127:817-830
5. Sacher M, Yu J, Barrowman J, Scarpa A, Burston J et al (1998) TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion. EMBO J 17:2494-2503
6. Sacher M, Kim Y-G, Lavie A, Oh B-H, Segev N (2008) The TRAPP complex: Insights into its architecture and function. Traffic 9:2032-2042
7. Lynch-Day MA, Bhandari D, Menon S, Huang J, Cai H et al (2010) Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy. Proc Natl Acad Sci 107:7811-7816
8. Tokarev AA, Taussig D, Sundaram G, Lipatova Z, Liang Y et al (2009) TRAPP II complex assembly requires Trs33 or Trs65. Traffic 10:1831-1844
9. Morozova N, Liang Y, Tokarev AA, Chen SH, Cox R et al (2006) TRAPPII subunits are required for the specificity switch of a Ypt-Rab GEF. Nat Cell Biol 8:1263-1269
10. Cai Y, Chin HF, Lazarova D, Menon S, Fu C et al (2008) The structural basis for activation of the Rab Ypt1p by the TRAPP membrane-tethering complexes. Cell 133:1202-1213
11. Yip CK, Berscheminski J, Walz T (2010) Molecular architecture of the TRAPPII complex and implications for vesicle tethering. Nat Struct Mol Biol 17:1298-1304
12. Zong M, X-g Wu, Chan CWL, Choi MY, Chan HC et al (2011) The adaptor function of TRAPPC2 in mammalian TRAPPs explains TRAPPC2-associated SEDT and TRAPPC9-associated congenital intellectual disability. PLoS ONE 6:e23350
13. Liang Y, Morozova N, Tokarev AA, Mulholland JW, Segev N (2007) The role of Trs65 in the Ypt/Rab guanine nucleotide exchange factor function of the TRAPP II complex. Mol Biol Cell 18:2533-2541
14. Choi C, Davey M, Schluter C, Pandher P, Fang Y et al (2011) Organization and assembly of the TRAPPII complex. Traffic 12:715-725
15. Scrivens PJ, Shahrzad N, Moores A, Morin A, Brunet S et al (2009) TRAPPC2L is a novel, highly conserved TRAPP-interacting protein. Traffic 10:724-736
16. Montpetit B, Conibear E (2009) Identification of the novel TRAPP associated protein Tca17. Traffic 10:713-723
17. Yamasaki A, Menon S, Yu S, Barrowman J, Meerloo T et al (2009) mTrs130 Is a component of a mammalian TRAPPII complex, a Rab1 GEF that binds to COPI coated vesicles. Mol Biol Cell 20:4205-4215
18. Sacher M, Barrowman J, Schieltz D, Yates JRI, Ferro-Novick S (2000) Identification and characterization of five new subunits of TRAPP. Eur J Cell Biol 79:71-80
19. Kummel D, Oeckinghaus A, Wang C, Krappmann D, Heinemann U (2008) Distinct isocomplexes of the TRAPP trafficking factor coexist inside human cells. FEBS Lett 582:3729-3733
20. Scrivens PJ, Noueihed B, Shahrzad N, Hul S, Brunet S et al (2011) C4orf41 and TTC-15 are mammalian TRAPP components with a role at an early stage in ER-to-Golgi trafficking. Mol Biol Cell 22:2083-2093
21. Wendler F, Gillingham AK, Sinka R, Rosa-Ferreira C, Gordon DE et al (2010) A genome-wide RNA interference screen identifies two novel components of the metazoan secretory pathway. EMBO J 29:304-314
22. Behrends C, Sowa ME, Gygi SP, Harper JW (2010) Network organization of the human autophagy system. Nature 466:68-76
23. Gavin A-C, Bosche M, Krause R, Grandi P, Marzioch M et al (2002) Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature 415:141-147
24. Yu S, Satoh A, Pypaert M, Mullen K, Hay JC et al (2006) mBet3p is required for homotypic COPII vesicle tethering in mammalian cells. J Cell Biol 174:359-368
25. Loh E, Peter F, Subramaniam VN, Hong W (2005) Mammalian Bet3 functions as a cytosolic factor participating in transport from the ER to the Golgi apparatus. J Cell Sci 118:1209-1222
26. Cai H, Yu S, Menon S, Cai Y, Lazarova D et al (2007) TRAPPI tethers COPII vesicles by binding the coat subunit Sec23. Nature 445:941-944
27. Bentley M, Liang Y, Mullen K, Xu D, Sztul E et al (2006) SNARE status regulates tether recruitment and function in homotypic COPII vesicle fusion. J Biol Chem 281:38825-38833
28. Allan B, Moyer B, Balch W (2000) Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion. Science 289:444-448
29. Price MA (2006) CKI, there's more than one: casein kinase I family members in Wnt and Hedgehog signaling. Genes Dev 20:399-410
30. Cheong JK, Virshup DM (2010) Casein kinase 1: complexity in the family. Int J Biochem Cell Biol 43:465-469
31. Cronlein J, Reuss S, Vollrath L (1990) Investigations on daynight differences of vesicle densities in synapses of the rat suprachiasmatic nucleus. Neurosci Lett 114:167-172
32. Mukai S, Matsushima S (1980) Effect of continuous darkness on diurnal rhythms in small vesicles in sympathetic nerve endings of the mouse pineal-quantitative electron microscopic observations. J Neural Transm 47:131-143
33. Kachi T (1979) Demonstration of circadian rhythm in granular vesicle number in pinealocytes of mice and the effect of light: semi-quantitative electron microscopic study. J Anatomy 129:603-614
34. Pevet P, Kuyper M (1978) The ultrastructure of pinealocytes in the golden mole (Amblysomus hottentotus) with special reference to the granular vesicles. Cell Tissue Res 191:39-56
35. Memon A, Hwang S, Deshpande N, Thompson GJ, Herrin D (1995) Novel aspects of the regulation of a cDNA(Arf1) from chlamydomonas with high sequence identity to animal ADPribosylation factor 1. Plant Mol Biol 29:567-577
36. Yu S, Roth MG (2002) Casein kinase I regulates membrane binding by ARF GAP1. Mol Biol Cell 13:2559-2570
37. Roth MG (1999) Snapshots of ARF1: implications for mechanisms of activation and inactivation. Cell 97:149-152
38. Siu KY, Yu MK, Wu X, Zong M, Roth MG et al (2011) The noncatalytic carboxyl-terminal domain of ARFGAP1 regulates actin cytoskeleton reorganization by antagonizing the activation of Rac1. PLoS ONE 6:e18458
39. Wang W, Sacher M, Ferro-Novick S (2000) TRAPP stimulates guanine nucleotide exchange on Ypt1p. J Cell Biol 151:289-296
40. Zou S, Liu Y, Zhang X, Chen Y, Ye M, et al (2012) Genetic analysis of exocytic Ypt/Rab GTPases and TRAPP subunits. Genetics (in press)
41. Barrowman J, Bhandari D, Reinisch K, Ferro-Novick S (2010) TRAPP complexes in membrane traffic: convergence through a common Rab. Nat Rev Mol Cell Biol 11:759-763
42. Westlake CJ, Baye LM, Nachury MV, Wright KJ, Ervin KE et al (2011) Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome. Proc Natl Acad Sci 108:2759-2764
43. Zhu Y, Hu L, Zhou Y, Yao Q, Liu L et al (2010) Structural mechanism of host Rab1 activation by the bifunctional Legionella type IV effector SidM/DrrA. Proc Natl Acad Sci 107:4699-4704
44. Nazarko TY, Huang J, Nicaud J-M, Klionsky DJ, Sibirny AA (2005) Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae. Autophagy 1:37-45
45. Meiling-Wesse K, Epple UD, Krick R, Barth H, Appelles A et al (2005) Trs85 (Gsg1), a component of the TRAPP complexes, is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway. J Biol Chem 280:33669-33678
46. Carlos Martín Zoppino F, Damián Militello R, Slavin I, A ́ lvarez C, Colombo MI (2010) Autophagosome formation depends on the small GTPase Rab1 and functional ER exit sites. Traffic 11:1246-1261
47. Reggiori F, Wang C-W, Nair U, Shintani T, Abeliovich H et al (2004) Early stages of the secretory pathway, but not endosomes, are required for Cvt vesicle and autophagosome assembly in Saccharomyces cerevisiae. Mol Biol Cell 15:2189-2204
48. Ishihara N, Hamasaki M, Yokota S, Suzuki K, Kamada Y et al (2001) Autophagosome requires specific early Sec proteins for its formation and NSF/SNARE for vacuolar fusion. Mol Biol Cell 12:3690-3702
49. Geng J, Nair U, Yasumura-Yorimitsu K, Klionsky DJ (2010) Post-Golgi sce proteins are required for autophagy in Saccharomyces cerevisiae. Mol Biol Cell 21:2257-2269
50. Simon G, Prekeris R (2008) Mechanisms regulating targeting of recycling endosomes to the cleavage furrow during cytokinesis. Biochem Soc Transact 36:391-394
51. Finger FP, White JG (2002) Fusion and fission: membrane trafficking in animal cytokinesis. Cell 108:727-730
52. Robinett CC, Giansanti MG, Gatti M, Fuller MT (2009) TRAPPII is required for cleavage furrow ingression and localization of Rab11 in dividing male meiotic cells of Drosophila. J Cell Sci 122:4526-4534
53. Sciorra VA, Audhya A, Parsons AB, Segev N, Boone C et al (2005) Synthetic genetic array analysis of the PtdIns 4-kinase Pik1p identifies components in a Golgi-specific Ypt31/rab-GTPase signaling pathway. Mol Biol Cell 16:776-793
54. Qi X, Kaneda M, Chen J, Geitmann A, Zheng H (2011) A specific role for Arabidopsis TRAPPII in post-Golgi trafficking that is crucial for cytokinesis and cell polarity. Plant J 68:234-248
55. Yoshimura S, Egerer J, Fuchs E, Haas A, Barr F (2007) Functional dissection of Rab GTPases involved in primary cilium formation. J Cell Biol 178:363-369
56. Zong M, Satoh A, Yu MK, Siu KY, Ng WY et al (2012) TRAPPC9 mediates the interaction between p150Glued and COPII vesicles at the target membrane. PLoS ONE 7:e29995
57. Watson P, Forster R, Palmer KJ, Pepperkok R, Stephens DJ (2005) Coupling of ER exit to microtubules through direct interaction of COPII with dynactin. Nat Cell Biol 7:48-55
58. Scales SJ, Pepperkok R, Kreis TE (1997) Visualization of ER-to-Golgi transport in living cells reveals a sequential mode of action for COPII and COPI. Cell 90:1137-1148
59. Presley JF, Cole NB, Schroer TA, Hirschberg K, Zaal KJM et al (1997) ER-to-Golgi transport visualized in living cells. Nature 389:81-85
60. Schroer TA (2004) DYNACTIN. Annu Rev Cell Dev Biol 20:759-779
61. Watson P, Stephens DJ (2006) Microtubule plus-end loading of p150Glued is mediated by EB1 and CLIP-170 but is not required for intracellular membrane traffic in mammalian cells. J Cell Sci 119:2758-2767
62. Trahey M, Hay JC (2010) Transport vesicle uncoating: it's later than you think. F1000 Biol Rep 2:47
63. Tang BL, Peter F, Krijnse-Locker J, Low SH, Griffiths G et al (1997) The mammalian homolog of yeast Sec13p is enriched in the intermediate compartment and is essential for protein transport from the endoplasmic reticulum to the Golgi apparatus. Mol Cell Biol 17:256-266
64. Savarirayan R, Thompson E, Gecz J (2003) Spondyloepiphyseal dysplasia tarda. Eur J Hum Genet 11:639-642
65. Gedeon AK, Colley A, Jamieson R, Thompson EM, Rogers J et al (1999) Identification of the gene (SEDL) causing X-linked spondyloepiphyseal dysplasia tarda. Nat Genet 22:400-404
66. Gecz J, Hillman MA, Gedeon AK, Cox TC, Baker E et al (2000) Gene structure and expression study of the SEDL gene for spondyloepiphyseal dysplasia tarda. Genomics 69:242-251
67. Sacher M (2003) Membrane traffic fuses with cartilage development. FEBS Lett 550:1-4
68. Lin Y, Rao S, Yang Y (2008) A novel mutation in the SEDL gene leading to X-linked spondyloepiphyseal dysplasia tarda in a large Chinese pedigree. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 25:150-153
69. Fiedler J, Merrer ML, Mortier G, Heuertz S, Faivre L et al (2004) X-linked spondyloepiphyseal dysplasia tarda: novel and recurrent mutations in 13 European families. Human Mutat 24:103
70. Bar-Yosef U, Ohana E, Hershkovitz E, Perlmuter S, Ofir R et al (2004) X-linked spondyloepiphyseal dysplasia tarda: a novel SEDL mutation in a Jewish Ashkenazi family and clinical intervention considerations. Am J Med Genet Part A 125A:45-48
71. Matsui Y, Yasui N, Ozono K, Yamagata M, Kawabata H et al (2001) Loss of the SEDL gene product (Sedlin) causes X-linked spondyloepiphyseal dysplasia tarda: identification of a molecular defect in a Japanese family. Am J Med Genet 99:328-330
72. Christie PT, Curley A, Nesbit MA, Chapman C, Genet S et al (2001) Mutational analysis in X-linked spondyloepiphyseal dysplasia tarda. J Clin Endocrinol Metab 86:3233-3236
73. Choi MY, Chan CCY, Chan D, Luk KDK, Cheah KSE et al (2009) Biochemical consequences of sedlin mutations that cause spondyloepiphyseal dysplasia tarda. Biochem J 423:233-242
74. Philippe O, Rio M, Carioux A, Plaza J-M, Guigue P et al (2009) Combination of linkage mapping and microarray-expression analysis identifies NF-jB signaling defect as a cause of autosomal-recessive mental retardation. Am J Human Genet 85:903-908
75. Mochida GH, Mahajnah M, Hill AD, Basel-Vanagaite L, Gleason D et al (2009) A truncating mutation of TRAPPC9 is associated with autosomal-recessive intellectual disability and postnatal microcephaly. Am J Human Genet 85:897-902
76. Mir A, Kaufman L, Noor A, Motazacker MM, Jamil T et al (2009) Identification of mutations in TRAPPC9, which encodes the NIKand IKK-b-binding protein, in nonsyndromic autosomal-recessive mental retardation. Am J Human Genet 85:909-915
77. Cai H, Zhang Y, Pypaert M, Walker L, Ferro-Novick S (2005) Mutants in trs120 disrupt traffic from the early endosome to the late Golgi. J Cell Biol 171:823-833
78. Hu W-H, Pendergast JS, Mo X-M, Brambilla R, Bracchi-Ricard V et al (2005) NIBP, a novel NIK and IKKb-binding protein that enhances NF-jB activation. J Biol Chem 280:29233-29241
79. Sadler KC, Amsterdam A, Soroka C, Boyer J, Hopkins N (2005) A genetic screen in zebrafish identifies the mutants vps18, nf2 and foie gras as models of liver disease. Development 132:3561-3572
80. Cinaroglu A, Gao C, Imrie D, Sadler KC (2011) Activating transcription factor 6 plays protective and pathological roles in steatosis due to endoplasmic reticulum stress in zebrafish. Hepatology 54:495-508
81. Walter P, Ron D (2011) The unfolded protein response: from stress pathway to homeostatic regulation. Science 334:1081-1086
82. Gwynn B, Smith R, Rowe L, Taylor B, Peters L (2006) A mouse TRAPP-related protein is involved in pigmentation. Genomics 88:196-203
83. Kummel D, Walter J, Heck M, Heinemann U, Veit M (2010) Characterization of the self-palmitoylation activity of the transport protein particle component Bet3. Cell Mol Life Sci 67:2653-2664
84. Kim Y-G, Sohn E, Seo J, Lee K, Lee H et al (2005) Crystal structure of bet3 reveals a novel mechanism for Golgi localization of tethering factor TRAPP. Nat Struct Mol Biol 12:38-45
85. Chen S, Cai H, Park S-K, Menon S, Jackson CL et al (2011) Trs65p, a subunit of the Ypt1p GEF TRAPPII, interacts with the Arf1p exchange factor Gea2p to facilitate COPI-mediated vesicle traffic. Mol Biol Cell 22:3634-3644
86. Zhang C, Bowzard J, Greene M, Anido A, Stearns K et al (2002) Genetic interactions link ARF1, YPT31/32 and TRS130. Yeast 19:1075-1086
87. Yamamoto K, Jigami Y (2002) Mutation of TRS130, which encodes a component of the TRAPP II complex, activates transcription of OCH1 in Saccharomyces cerevisiae. Curr Genet 42:85-93
88. Ethell IM, Hagihara K, Miura Y, Irie F, Yamaguchi Y (2000) Synbindin, a novel syndecan-2-binding protein in neuronal dendritic spines. J Cell Biol 151:53-68
89. Zhao S-L, Hong J, Xie Z-Q, Tang J-T, Su W-Y et al (2011) TRAPPC4-ERK2 interaction activates ERK1/2, modulates its nuclear localization and regulates proliferation and apoptosis of colorectal cancer cells. PLoS ONE 6:e23262
90. Liu X, Wang Y, Zhu H, Zhang Q, Xing X et al (2010) Interaction of Sedlin with PAM14. J Cell Biochem 109:1129-1133
91. Jeyabalan J, Nesbit MA, Galvanovskis J, Callaghan R, Rorsman P et al (2010) SEDLIN forms homodimers: characterisation of SEDLIN mutations and their interactions with transcription factors MBP1, PITX1 and SF1. PLoS ONE 5:e10646
92. Fan L, Yu W, Zhu X (2003) Interaction of Sedlin with chloride intracellular channel proteins. FEBS Lett 540:77-80