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Volumn 178, Issue 2, 2012, Pages 935-948

Bone marrow mesenchymal stem cells ameliorate hepatic ischemia/reperfusion injuries via inactivation of the MEK/ERK signaling pathway in rats

Author keywords

Apoptosis; Ischemia reperfusion injury; Liver transplantation; Mesenchymal stem cell; Reactive oxygen species

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE;

EID: 84869079210     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2012.04.070     Document Type: Article
Times cited : (72)

References (38)
  • 1
    • 59649091509 scopus 로고    scopus 로고
    • Recovery of warm ischemic rat liver grafts by normothermic extracorporeal perfusion
    • H. Tolboom, R.E. Pouw, and M.L. Izamis Recovery of warm ischemic rat liver grafts by normothermic extracorporeal perfusion Transplantation 87 2009 170
    • (2009) Transplantation , vol.87 , pp. 170
    • Tolboom, H.1    Pouw, R.E.2    Izamis, M.L.3
  • 2
    • 6444241320 scopus 로고    scopus 로고
    • Liver transplantation from non-heart-beating donors: Current status and future prospects
    • S. Reddy, M. Zilvetti, and J. Brockmann Liver transplantation from non-heart-beating donors: Current status and future prospects Liver Transpl 10 2004 1223
    • (2004) Liver Transpl , vol.10 , pp. 1223
    • Reddy, S.1    Zilvetti, M.2    Brockmann, J.3
  • 3
    • 33646894690 scopus 로고    scopus 로고
    • Microcirculation and reperfusion injury in organ transplantation
    • G. Cicco, P.C. Panzera, and G. Catalano Microcirculation and reperfusion injury in organ transplantation Adv Exp Med Biol 566 2005 363
    • (2005) Adv Exp Med Biol , vol.566 , pp. 363
    • Cicco, G.1    Panzera, P.C.2    Catalano, G.3
  • 5
    • 55649119738 scopus 로고    scopus 로고
    • The influence of retrograde reperfusion on the ischaemia/reperfusion injury after liver transplantation in the rat
    • H. Kern, C. Bald, and T. Brill The influence of retrograde reperfusion on the ischaemia/reperfusion injury after liver transplantation in the rat Int J Exp Pathol 89 2008 433
    • (2008) Int J Exp Pathol , vol.89 , pp. 433
    • Kern, H.1    Bald, C.2    Brill, T.3
  • 6
    • 0033429387 scopus 로고    scopus 로고
    • The mitochondrial permeability transition and the calcium, oxygen and pH paradoxes: One paradox after another
    • J.J. Lemasters The mitochondrial permeability transition and the calcium, oxygen and pH paradoxes: One paradox after another Cardiovasc Res 44 1999 470
    • (1999) Cardiovasc Res , vol.44 , pp. 470
    • Lemasters, J.J.1
  • 7
    • 67651151359 scopus 로고    scopus 로고
    • Histological and biochemical alterations in early-stage lobar ischemia-reperfusion in rat liver
    • H.A. Arab, F. Sasani, and M.H. Rafiee Histological and biochemical alterations in early-stage lobar ischemia-reperfusion in rat liver World J Gastroenterol 15 2009 1951
    • (2009) World J Gastroenterol , vol.15 , pp. 1951
    • Arab, H.A.1    Sasani, F.2    Rafiee, M.H.3
  • 8
    • 34247854809 scopus 로고    scopus 로고
    • Vasculotropic, paracrine actions of infused mesenchymal stem cells are important to the recovery from acute kidney injury
    • F. Tögel, K. Weiss, and Y. Yang Vasculotropic, paracrine actions of infused mesenchymal stem cells are important to the recovery from acute kidney injury Am J Physiol Renal Physiol 292 2007 F1626
    • (2007) Am J Physiol Renal Physiol , vol.292 , pp. 1626
    • Tögel, F.1    Weiss, K.2    Yang, Y.3
  • 9
    • 0016269155 scopus 로고
    • Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivo
    • A.J. Friedenstein, R.K. Chailakhyan, and N.V. Latsinik Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivo Transplantation 17 1974 331
    • (1974) Transplantation , vol.17 , pp. 331
    • Friedenstein, A.J.1    Chailakhyan, R.K.2    Latsinik, N.V.3
  • 10
    • 36248959280 scopus 로고    scopus 로고
    • Therapeutic applications of mesenchymal stromal cells
    • G. Brooke, M. Cook, and C. Blair Therapeutic applications of mesenchymal stromal cells Semin Cell Dev Biol 18 2007 846
    • (2007) Semin Cell Dev Biol , vol.18 , pp. 846
    • Brooke, G.1    Cook, M.2    Blair, C.3
  • 11
    • 55049135589 scopus 로고    scopus 로고
    • Ex vivo pretreatment with melatonin improves survival, proangiogenic/mitogenic activity, and efficiency of mesenchymal stem cells injected into ischemic kidney
    • C. Mias, E. Trouche, and M.H. Seguelas Ex vivo pretreatment with melatonin improves survival, proangiogenic/mitogenic activity, and efficiency of mesenchymal stem cells injected into ischemic kidney Stem Cells 26 2008 1749
    • (2008) Stem Cells , vol.26 , pp. 1749
    • Mias, C.1    Trouche, E.2    Seguelas, M.H.3
  • 12
    • 20844440562 scopus 로고    scopus 로고
    • Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms
    • F. Tögel, Z. Hu, and K. Weiss Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms Am J Physiol Renal Physiol 289 2005 F31
    • (2005) Am J Physiol Renal Physiol , vol.289 , pp. 31
    • Tögel, F.1    Hu, Z.2    Weiss, K.3
  • 13
    • 33646758917 scopus 로고    scopus 로고
    • Pretreatment with adult progenitor cells improves recovery and decreases native myocardial proinflammatory signaling after ischemia
    • M. Wang, B.M. Tsai, and P.R. Crisostomo Pretreatment with adult progenitor cells improves recovery and decreases native myocardial proinflammatory signaling after ischemia Shock 25 2006 454
    • (2006) Shock , vol.25 , pp. 454
    • Wang, M.1    Tsai, B.M.2    Crisostomo, P.R.3
  • 14
    • 33646252939 scopus 로고    scopus 로고
    • Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement
    • M. Gnecchi, H. He, and N. Noiseux Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement FASEB J 20 2006 661
    • (2006) FASEB J , vol.20 , pp. 661
    • Gnecchi, M.1    He, H.2    Noiseux, N.3
  • 15
    • 70849110426 scopus 로고    scopus 로고
    • Poor cell survival limits the beneficial impact of mesenchymal stem cell transplantation on acute kidney injury
    • V.R. Burst, M. Gillis, and F. Pütsch Poor cell survival limits the beneficial impact of mesenchymal stem cell transplantation on acute kidney injury Nephron Exp Nephrol 114 2010 e107
    • (2010) Nephron Exp Nephrol , vol.114 , pp. 107
    • Burst, V.R.1    Gillis, M.2    Pütsch, F.3
  • 16
    • 57049089034 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells for the treatment of ischemic stroke
    • P. Dharmasaroja Bone marrow-derived mesenchymal stem cells for the treatment of ischemic stroke J Clin Neurosci 16 2009 12
    • (2009) J Clin Neurosci , vol.16 , pp. 12
    • Dharmasaroja, P.1
  • 17
    • 79955636239 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells reduce intestinal ischemia/reperfusion injuries in rats
    • H. Jiang, L. Qu, and Y. Li Bone marrow mesenchymal stem cells reduce intestinal ischemia/reperfusion injuries in rats J Surg Res 168 2011 127
    • (2011) J Surg Res , vol.168 , pp. 127
    • Jiang, H.1    Qu, L.2    Li, Y.3
  • 18
    • 0027319824 scopus 로고
    • Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury. Modulating effects of FK-506 and cyclosporine
    • S. Suzuki, L.H. Toledo-Pereyra, and F.J. Rodriguez Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury. Modulating effects of FK-506 and cyclosporine Transplantation 55 1993 1265
    • (1993) Transplantation , vol.55 , pp. 1265
    • Suzuki, S.1    Toledo-Pereyra, L.H.2    Rodriguez, F.J.3
  • 19
    • 77953022144 scopus 로고    scopus 로고
    • Molecular signature linked to acute phase injury and tumor invasiveness in small-for-size liver grafts
    • K. Man, K.C. Shih, and K.T. Ng Molecular signature linked to acute phase injury and tumor invasiveness in small-for-size liver grafts Ann Surg 251 2010 1154
    • (2010) Ann Surg , vol.251 , pp. 1154
    • Man, K.1    Shih, K.C.2    Ng, K.T.3
  • 20
    • 33645799492 scopus 로고    scopus 로고
    • Mechanisms of liver injury. I. TNF-alpha-induced liver injury: Role of IKK, JNK, and ROS pathways
    • R.F. Schwabe, and D.A. Brenner Mechanisms of liver injury. I. TNF-alpha-induced liver injury: Role of IKK, JNK, and ROS pathways Am J Physiol Gastrointest Liver Physiol 290 2006 G583
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290 , pp. 583
    • Schwabe, R.F.1    Brenner, D.A.2
  • 21
    • 0033860297 scopus 로고    scopus 로고
    • Reactive oxygen and mechanisms of inflammatory liver injury
    • H. Jaeschke Reactive oxygen and mechanisms of inflammatory liver injury J Gastroenterol Hepatol 15 2000 718
    • (2000) J Gastroenterol Hepatol , vol.15 , pp. 718
    • Jaeschke, H.1
  • 22
    • 77952238570 scopus 로고    scopus 로고
    • Mesenchymal stem cells derived from human umbilical cord ameliorate ischemia/reperfusion-induced acute renal failure in rats
    • H. Cao, H. Qian, and W. Xu Mesenchymal stem cells derived from human umbilical cord ameliorate ischemia/reperfusion-induced acute renal failure in rats Biotechnol Lett 32 2010 725
    • (2010) Biotechnol Lett , vol.32 , pp. 725
    • Cao, H.1    Qian, H.2    Xu, W.3
  • 23
    • 7644231873 scopus 로고    scopus 로고
    • Ischemic preconditioning protects hepatocytes via reactive oxygen species derived from Kupffer cells in rats
    • K. Tejima, M. Arai, and H. Ikeda Ischemic preconditioning protects hepatocytes via reactive oxygen species derived from Kupffer cells in rats Gastroenterology 127 2004 1488
    • (2004) Gastroenterology , vol.127 , pp. 1488
    • Tejima, K.1    Arai, M.2    Ikeda, H.3
  • 24
    • 24144452193 scopus 로고    scopus 로고
    • Significance and therapeutic potential of prostaglandin E2 receptor in hepatic ischemia/reperfusion injury in mice
    • Y. Kuzumoto, M. Sho, and N. Ikeda Significance and therapeutic potential of prostaglandin E2 receptor in hepatic ischemia/reperfusion injury in mice Hepatology 42 2005 608
    • (2005) Hepatology , vol.42 , pp. 608
    • Kuzumoto, Y.1    Sho, M.2    Ikeda, N.3
  • 25
    • 0036711273 scopus 로고    scopus 로고
    • DNA damage and apoptosis in hydrogen peroxide-exposed Jurkat cells: Bolus addition versus continuous generation of H(2)O(2)
    • A. Barbouti, P.T. Doulias, and L. Nousis DNA damage and apoptosis in hydrogen peroxide-exposed Jurkat cells: Bolus addition versus continuous generation of H(2)O(2) Free Radic Biol Med 33 2002 691
    • (2002) Free Radic Biol Med , vol.33 , pp. 691
    • Barbouti, A.1    Doulias, P.T.2    Nousis, L.3
  • 26
    • 77649203007 scopus 로고    scopus 로고
    • Protective effects of lycopene against H2O2-induced oxidative injury and apoptosis in human endothelial cells
    • X. Tang, X. Yang, and Y. Peng Protective effects of lycopene against H2O2-induced oxidative injury and apoptosis in human endothelial cells Cardiovasc Drugs Ther 23 2009 439
    • (2009) Cardiovasc Drugs Ther , vol.23 , pp. 439
    • Tang, X.1    Yang, X.2    Peng, Y.3
  • 27
    • 0032240594 scopus 로고    scopus 로고
    • Mechanisms of reperfusion injury after warm ischemia of the liver
    • H. Jaeschke Mechanisms of reperfusion injury after warm ischemia of the liver J Hepatobiliary Pancreat Surg 5 1998 402
    • (1998) J Hepatobiliary Pancreat Surg , vol.5 , pp. 402
    • Jaeschke, H.1
  • 28
    • 34547402979 scopus 로고    scopus 로고
    • Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury
    • L.A. Ortiz, M. Dutreil, and C. Fattman Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury Proc Natl Acad Sci U S A 104 2007 11002
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 11002
    • Ortiz, L.A.1    Dutreil, M.2    Fattman, C.3
  • 29
    • 23944519424 scopus 로고    scopus 로고
    • Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy
    • E. Zappia, S. Casazza, and E. Pedemonte Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy Blood 106 2005 1755
    • (2005) Blood , vol.106 , pp. 1755
    • Zappia, E.1    Casazza, S.2    Pedemonte, E.3
  • 30
    • 57349177854 scopus 로고    scopus 로고
    • VEGF is critical for stem cell-mediated cardioprotection and a crucial paracrine factor for defining the age threshold in adult and neonatal stem cell function
    • T.A. Markel, Y. Wang, and J.L. Herrmann VEGF is critical for stem cell-mediated cardioprotection and a crucial paracrine factor for defining the age threshold in adult and neonatal stem cell function Am J Physiol Heart Circ Physiol 295 2008 H2308
    • (2008) Am J Physiol Heart Circ Physiol , vol.295 , pp. 2308
    • Markel, T.A.1    Wang, Y.2    Herrmann, J.L.3
  • 31
    • 39049172421 scopus 로고    scopus 로고
    • Administration of bone marrow-derived stem cells suppresses cellular necrosis and apoptosis induced by reperfusion of ischaemic kidneys in rats
    • Y. Wang, F. Hu, and Z.J. Wang Administration of bone marrow-derived stem cells suppresses cellular necrosis and apoptosis induced by reperfusion of ischaemic kidneys in rats Chin Med J (Engl) 121 2008 268
    • (2008) Chin Med J (Engl) , vol.121 , pp. 268
    • Wang, Y.1    Hu, F.2    Wang, Z.J.3
  • 32
    • 12144287799 scopus 로고    scopus 로고
    • Secretion of angiogenic and antiapoptotic factors by human adipose stromal cells
    • J. Rehman, D. Traktuev, and J. Li Secretion of angiogenic and antiapoptotic factors by human adipose stromal cells Circulation 109 2004 1292
    • (2004) Circulation , vol.109 , pp. 1292
    • Rehman, J.1    Traktuev, D.2    Li, J.3
  • 33
    • 34547281072 scopus 로고    scopus 로고
    • Hepatocyte differentiation of mesenchymal stem cells from rat peritoneal adipose tissue in vitro and in vivo
    • M. Sgodda, H. Aurich, and S. Kleist Hepatocyte differentiation of mesenchymal stem cells from rat peritoneal adipose tissue in vitro and in vivo Exp Cell Res 313 2007 2875
    • (2007) Exp Cell Res , vol.313 , pp. 2875
    • Sgodda, M.1    Aurich, H.2    Kleist, S.3
  • 34
    • 77957325263 scopus 로고    scopus 로고
    • MEK/ERK pathway mediates cytoprotection of salvianolic acid B against oxidative stress-induced apoptosis in rat bone marrow stem cells
    • B. Lu, Z. Ye, and Y. Deng MEK/ERK pathway mediates cytoprotection of salvianolic acid B against oxidative stress-induced apoptosis in rat bone marrow stem cells Cell Biol Int 34 2010 1063
    • (2010) Cell Biol Int , vol.34 , pp. 1063
    • Lu, B.1    Ye, Z.2    Deng, Y.3
  • 35
    • 0034671751 scopus 로고    scopus 로고
    • Requirement for ERK activation in cisplatin-induced apoptosis
    • X. Wang, J.L. Martindale, and N.J. Holbrook Requirement for ERK activation in cisplatin-induced apoptosis J Biol Chem 275 2000 39435
    • (2000) J Biol Chem , vol.275 , pp. 39435
    • Wang, X.1    Martindale, J.L.2    Holbrook, N.J.3
  • 36
    • 25144462628 scopus 로고    scopus 로고
    • Role of ERK activation in cisplatin-induced apoptosis in OK renal epithelial cells
    • Y.K. Kim, H.J. Kim, and C.H. Kwon Role of ERK activation in cisplatin-induced apoptosis in OK renal epithelial cells J Appl Toxicol 25 2005 374
    • (2005) J Appl Toxicol , vol.25 , pp. 374
    • Kim, Y.K.1    Kim, H.J.2    Kwon, C.H.3
  • 37
    • 44449179744 scopus 로고    scopus 로고
    • Salvianolic acid B inhibits hydrogen peroxide-induced endothelial cell apoptosis through regulating PI3K/Akt signaling
    • C.L. Liu, L.X. Xie, and M. Li Salvianolic acid B inhibits hydrogen peroxide-induced endothelial cell apoptosis through regulating PI3K/Akt signaling PLoS One 2 2007 e1321
    • (2007) PLoS One , vol.2 , pp. 1321
    • Liu, C.L.1    Xie, L.X.2    Li, M.3
  • 38
    • 49949089674 scopus 로고    scopus 로고
    • Propofol protects hepatic L02 cells from hydrogen peroxide-induced apoptosis via activation of extracellular signal-regulated kinases pathway
    • H. Wang, Z. Xue, and Q. Wang Propofol protects hepatic L02 cells from hydrogen peroxide-induced apoptosis via activation of extracellular signal-regulated kinases pathway Anesth Analg 107 2008 534
    • (2008) Anesth Analg , vol.107 , pp. 534
    • Wang, H.1    Xue, Z.2    Wang, Q.3


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