A Randomized Clinical Trial of Recombinant Human Hyaluronidase-Facilitated Subcutaneous Versus Intravenous Rehydration in Mild to Moderately Dehydrated Children in the Emergency Department

Clinical Therapeutics

Volumn 34, Issue 11, 2012, Pages 2232-2245

  Spandorfer, Philip R ^a,b   Mace, Sharon E ^c   Okada, Pamela J ^d   Simon, Harold K ^e,f   Allen, Coburn H ^g   Spiro, David M ^h   Friend, Keith ⁱ   Harb, George ⁱ   Lebel, Francois ⁱ  

^a CHILDREN'S HEALTHCARE OF ATLANTA   (United States)

^b Pediatric Emergency Medicine Associates   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

^d CHILDREN S MEDICAL CENTER   (United States)

^e EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f Children's Healthcare of Atlanta at Egleston   (United States)

^g DELL INC   (United States)

^h OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

ⁱ BAXTER HEALTHCARE CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; INFUSION FLUID; ISOTONIC SOLUTION; METRONIDAZOLE; ORAL REHYDRATION SOLUTION; RECOMBINANT HYALURONIDASE;

ARTICLE; CARDIOPULMONARY ARREST; CHILD; CONTROLLED STUDY; DEHYDRATION; DIARRHEA; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; EMERGENCY WARD; ERYTHEMA; FEMALE; FEVER; HOSPITAL PATIENT; HOSPITALIZATION; HUMAN; HYPODERMOCLYSIS; INFANT; INJECTION SITE PAIN; INTENTION TO TREAT ANALYSIS; MAJOR CLINICAL STUDY; MALE; MUCOCUTANEOUS LYMPH NODE SYNDROME; NAUSEA AND VOMITING; ORAL REHYDRATION THERAPY; PEDIATRICS; PHASE 4 CLINICAL TRIAL; PNEUMONIA; PRESCHOOL CHILD; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; ROTAVIRUS INFECTION; SCHOOL CHILD; SWELLING; TREATMENT OUTCOME; VIRAL GASTROENTERITIS; WEIGHT CHANGE;

ANTIGENS, NEOPLASM; BODY WEIGHT; CHILD; CHILD, PRESCHOOL; DEHYDRATION; EMERGENCY SERVICE, HOSPITAL; FEMALE; FLUID THERAPY; HISTONE ACETYLTRANSFERASES; HOSPITALIZATION; HUMANS; HYALURONOGLUCOSAMINIDASE; HYPODERMOCLYSIS; INFANT; INFUSIONS, INTRAVENOUS; ISOTONIC SOLUTIONS; MALE; PROSPECTIVE STUDIES; QUESTIONNAIRES; RECOMBINANT PROTEINS; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TREATMENT OUTCOME; UNITED STATES;

EID: 84869069138     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/j.clinthera.2012.09.011     Document Type: Article

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