Calcium-permeable α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors trigger neuronal nitric-oxide synthase activation to promote nerve cell death in an Src kinase-dependent fashion

Journal of Biological Chemistry

Volumn 287, Issue 46, 2012, Pages 38680-38694

  Socodato, Renato ^a,b   Santiago, Felipe N ^a   Portugal, Camila C ^a,b   Domingues, Ana F ^c   Santiago, Ana R ^b   Relvas, João B ^c   Ambróio, António F ^b   Paes de Carvalho, Roberto ^a  

^a FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF PORTO   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

ACID RECEPTORS; AMPA-RECEPTOR; APOPTOTIC; CRITICAL STEPS; DOWNSTREAM TARGET; EXCITATORY NEUROTRANSMISSION; GLIAL CELLS; GLUTAMATE RECEPTOR; GUANYLYL CYCLASE; IMMUNOCYTOCHEMISTRY; IN-VIVO; INFORMATION DECODING; INHIBITORY SITES; NITRIC-OXIDE SYNTHASE; NO DONOR; PHOSPHOTYROSINE; RETINAL CELLS; WESTERN BLOTTING;

AMINO ACIDS; CALCIUM; CELL CULTURE; CELL DEATH; ENZYMES; MODULATION; NITRIC ACID; NITRIC OXIDE; OPHTHALMOLOGY; PHOSPHORYLATION;

NEURONS;

ACETIC ACID DERIVATIVE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; CHLORPHENIRAMINE MALEATE PLUS PHENYLEPHRINE; GLUTAMATE RECEPTOR; LIFICIGUAT; MITOGEN ACTIVATED PROTEIN KINASE; N ACETYL S NITROSOPENICILLAMINE; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; PHOSPHOTYROSINE; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GLIA CELL; IN VIVO STUDY; MALE; NERVE CELL NECROSIS; NERVE CELL STIMULATION; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; RETINA NERVE CELL; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; APOPTOSIS; CALCIUM; CALCIUM SIGNALING; CELL DEATH; CHICK EMBRYO; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; MALE; NEURONS; NITRIC OXIDE SYNTHASE TYPE I; PHOSPHORYLATION; RATS; RATS, LONG-EVANS; RATS, WISTAR; RECEPTORS, GLUTAMATE; RETINA; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 84869061341     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.353961     Document Type: Article

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