Molecular and Pharmacological Characterization of Serotonin 5-HT2α and 5-HT7 Receptors in the Salivary Glands of the Blowfly Calliphora vicina

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Röser, Claudia ^a   Jordan, Nadine ^b   Balfanz, Sabine ^b   Baumann, Arnd ^b   Walz, Bernd ^a   Baumann, Otto ^a   Blenau, Wolfgang ^a,c  

^a UNIVERSITY OF POTSDAM   (Germany)

^b FORSCHUNGSZENTRUM JÜLICH   (Germany)

^c GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

5 CARBAMOYLTRYPTAMINE; 5 METHOXYTRYPTAMINE; CALCIUM ION; CLOZAPINE; COMPLEMENTARY DNA; CYCLIC AMP; MESSENGER RNA; SEROTONIN 2A RECEPTOR; SEROTONIN 7 RECEPTOR;

ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALLIPHORA VICINA; CALLIPHORIDAE; CELL STIMULATION; CONTROLLED STUDY; MAMMAL CELL; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALIVARY GLAND; SEROTONIN 2A RECEPTOR GENE; SEROTONIN 7 RECEPTOR GENE; STRUCTURE ANALYSIS;

ANIMALS; CLONING, MOLECULAR; DIPTERA; INSECT PROTEINS; MOLECULAR SEQUENCE DATA; PHYLOGENY; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, SEROTONIN; SALIVARY GLANDS; SEQUENCE ANALYSIS, PROTEIN; SEROTONIN;

CALLIPHORA VICINA; MAMMALIA;

EID: 84869053056     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0049459     Document Type: Article

References (60)

1. Berridge MJ, (2005) Unlocking the secrets of cell signaling. Annu Rev Physiol 67: 1-21.
2. Baumann O, Walz B, (2012) The blowfly salivary gland- A model system for analyzing the regulation of plasma membrane V-ATPase. J Insect Physiol 58: 450-458.
3. Berridge MJ, Patel NG, (1968) Insect salivary glands: Stimulation of fluid secretion by 5-hydroxytryptamine and adenosine-3', 5'-monophosphate. Science 162: 462-463.
4. Trimmer BA, (1985) Serotonin and the control of salivation in the blowfly Calliphora. J Exp Biol 114: 307-328.
5. Hansen Bay CM, (1978) Control of salivation in the blowfly Calliphora. J Exp Biol 75: 189-201.
6. Nässel DR, Elekes K, (1985) Serotonergic terminals in the neural sheath of the blowfly nervous system: electron microscopical immunocytochemistry and 5,7-dihydroxytryptamine labelling. Neuroscience 15: 293-307.
7. Heslop JP, Berridge MJ, (1980) Changes in cyclic AMP and cyclic GMP concentrations during the action of 5-hydroxytryptamine on an insect salivary gland. Biochem J 192: 247-255.
8. Berridge MJ, (1980) Preliminary measurements of intracellular calcium in an insect salivary gland using a calcium-sensitive microelectrode. Cell Calcium 1: 217-227.
9. Prince WT, Berridge MJ, (1973) The role of calcium in the action of 5-hydroxytryptamine and cyclic AMP on salivary glands. J Exp Biol 58: 367-384.
10. Berridge MJ, Lindley BD, Prince WT, (1976) Studies on the mechanism of fluid secretion by isolated salivary glands of Calliphora. J Exp Biol 64: 311-322.
11. Rein J, Voss M, Blenau W, Walz B, Baumann O, (2008) Hormone-induced assembly and activation of V-ATPase in blowfly salivary glands is mediated by protein kinase A. Am J Physiol Cell Physiol. 294: C56-C65.
12. Berridge MJ, (1981) Electrophysiological evidence for the existence of separate receptor mechanisms mediating the action of 5-hydroxytryptamine. Mol Cell Endocrinol 23: 91-104.
13. Berridge MJ, Heslop JP, (1981) Separate 5-hydroxytryptamine receptors on the salivary gland of the blowfly are linked to the generation of either cyclic adenosine 3',5'-monophosphate or calcium signals. Br J Pharmacol 73: 729-738.
14. Schmidt R, Baumann O, Walz B, (2008) cAMP potentiates InsP3-induced Ca2+ release from the endoplasmic reticulum in blowfly salivary glands. BMC Physiol 8: 10.
15. Voss M, Fechner L, Walz B, Baumann O, (2010) Calcineurin activity augments cAMP/PKA-dependent activation of V-ATPase in blowfly salivary glands. Am J Physiol Cell Physiol 298: C1047-C1056.
16. Heindorff K, Blenau W, Walz B, Baumann O, (2012) Characterization of a Ca2+/calmodulin-dependent AC1 adenylyl cyclase in a non-neuronal tissue, the blowfly salivary gland. Cell Calcium 52: 103-112.
17. Nichols DE, Nichols CD, (2008) Serotonin receptors. Chem Rev 108: 1614-1641.
18. Hauser F, Cazzamali G, Williamson M, Blenau W, Grimmelikhuijzen CJ, (2006) A review of neurohormone GPCRs present in the fruitfly Drosophila melanogaster and the honey bee Apis mellifera. Prog Neurobiol 80: 1-19.
19. Blenau W, Thamm M, (2011) Distribution of serotonin (5-HT) and its receptors in the insect brain with focus on the mushroom bodies: lessons from Drosophila melanogaster and Apis mellifera. Arthropod Struct Dev 40: 381-394.
20. Saudou F, Boschert U, Amlaiky N, Plassat JL, Hen R, (1992) A family of Drosophila serotonin receptors with distinct intracellular signalling properties and expression patterns. EMBO J 11: 7-17.
21. Troppmann B, Balfanz S, Baumann A, Blenau W, (2010) Inverse agonist and neutral antagonist actions of synthetic compounds at an insect 5-HT1 receptor. Br J Pharmacol 159: 1450-1462.
22. Thamm M, Balfanz S, Scheiner R, Baumann A, Blenau W, (2010) Characterization of the 5-HT1A receptor of the honey bee (Apis mellifera) and involvement of serotonin in phototactic behavior. Cell Mol Life Sci 67: 2467-2479.
23. Witz P, Amlaiky N, Plassat JL, Maroteaux L, Borrelli E, et al. (1990) Cloning and characterization of a Drosophila serotonin receptor that activates adenylate cyclase. Proc Natl Acad Sci USA 87: 8940-8944.
24. Schlenstedt J, Balfanz S, Baumann A, Blenau W, (2006) Am5-HT7: molecular and pharmacological characterization of the first serotonin receptor of the honeybee (Apis mellifera). J Neurochem 98: 1985-1998.
25. Hall TA, (1999) BioEdit: A user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucleic Acids Symp Ser 41: 95-98.
26. Tamura K, Peterson D, Peterson N, Stecher G, Nei M, et al. (2011) MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol 28: 2731-2739.
27. Kozak M, (1984) Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs. Nucleic Acids Res 12: 857-872.
28. Wachten S, Schlenstedt J, Gauss R, Baumann A, (2006) Molecular identification and functional characterization of an adenylyl cyclase from the honeybee. J Neurochem 96: 1580-1590.
29. Ludwig J, Margalit T, Eismann E, Lancet D, Kaupp UB, (1990) Primary structure of cAMP-gated channel from bovine olfactory epithelium. FEBS Lett 270: 24-29.
30. Chen C, Okayama H, (1987) High-efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol 7: 2745-2752.
31. Grohmann L, Blenau W, Erber J, Ebert PR, Strünker T, et al. (2003) Molecular and functional characterization of an octopamine receptor from honeybee (Apis mellifera) brain. J Neurochem 86: 725-735.
32. Berridge MJ, Prince WT, (1972) Transepithelial potential changes during stimulation of isolated salivary glands with 5-hydroxytryptamine and cyclic AMP. J Exp Biol 56: 139-153.
33. Vetter I, Lewis RJ, (2010) Characterization of endogenous calcium responses in neuronal cell lines. Biochem Pharmacol 79: 908-920.
34. Prioleau C, Visiers I, Ebersole BJ, Weinstein H, Sealfon SC, (2002) Conserved helix 7 tyrosine acts as a multistate conformational switch in the 5HT2C receptor. Identification of a novel "locked-on" phenotype and double revertant mutations. J Biol Chem 277: 36577-36584.
35. Fritze O, Filipek S, Kuksa V, Palczewski K, Hofmann KP, et al. (2003) Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation. Proc Natl Acad Sci USA 100: 2290-2295.
36. Flanagan CA, (2005) A GPCR that is not "DRY". Mol Pharmacol 68: 1-3.
37. Rovati GE, Capra V, Neubig RR, (2007) The highly conserved DRY motif of class A G protein-coupled receptors: beyond the ground state. Mol Pharmacol 71: 959-964.
38. Colas JF, Launay JM, Kellermann O, Rosay P, Maroteaux L, (1995) Drosophila 5-HT2 serotonin receptor: coexpression with fushi-tarazu during segmentation. Proc Natl Acad Sci USA 92: 5441-5445.
39. Papoucheva E, Dumuis A, Sebben M, Richter DW, Ponimaskin EG, (2004) The 5-hydroxytryptamine(1A) receptor is stably palmitoylated, and acylation is critical for communication of receptor with Gi protein. J Biol Chem 279: 3280-3291.
40. Gerhardt CC, Leysen JE, Planta RJ, Vreugdenhil E, Van Heerikhuizen H, (1996) Functional characterisation of a 5-HT2 receptor cDNA cloned from Lymnaea stagnalis. Eur J Pharmacol 311: 249-258.
41. Saudou F, Amlaiky N, Plassat JL, Borrelli E, Hen R, (1990) Cloning and characterization of a Drosophila tyramine receptor. EMBO J 9: 3611-3617.
42. Pietrantonio PV, Jagge C, McDowell C, (2001) Cloning and expression analysis of a 5HT7-like serotonin receptor cDNA from mosquito Aedes aegypti female excretory and respiratory systems. Insect Mol Biol 10: 357-369.
43. Baxter G, Barker SC, (1999) Isolation of a cDNA for an octopamine-like, G-protein coupled receptor from the cattle tick, Boophilus microplus. Insect Biochem Mol Biol 29: 461-467.
44. Lee DW, Pietrantonio PV, (2003) In vitro expression and pharmacology of the 5-HT7-like receptor present in the mosquito Aedes aegypti tracheolar cells and hindgut-associated nerves. Insect Mol Biol 12: 561-569.
45. Hobson RJ, Hapiak VM, Xiao H, Buehrer KL, Komuniecki PR, et al. (2006) SER-7, a Caenorhabditis elegans 5-HT7-like receptor, is essential for the 5-HT stimulation of pharyngeal pumping and egg laying. Genetics 172: 159-169.
46. Chintapalli VR, Wang J, Dow JA, (2007) Using FlyAtlas to identify better Drosophila melanogaster models of human disease. Nat Genet 39: 715-720.
47. Oschman JL, Berridge MJ, (1970) Structural and functional aspects of salivary fluid section in Calliphora. Tissue Cell 2: 281-310.
48. Zimmermann B, Walz B, (1997) Serotonin-induced intercellular calcium wave in salivary glands of the blowfly Calliphora erythrocephala. J Physiol 500: 17-28.
49. Rein J, Zimmermann B, Hille C, Lang I, Walz B, et al. (2006) Fluorescence measurements of serotonin-induced V-ATPase-dependent pH changes at the luminal surface in salivary glands of the blowy Calliphora vicina. J Exp Biol 209: 1716-1724.
50. Schaerlinger B, Launay JM, Vonesch JL, Maroteaux L, (2007) Gain of affinity point mutation in the serotonin receptor gene 5-HT2Dro accelerates germband extension movements during Drosophila gastrulation. Dev Dyn 236: 991-999.
51. Colas JF, Choi DS, Launay JM, Maroteaux L, (1997) Evolutionary conservation of the 5-HT2B receptors. Ann NY Acad Sci 812: 149-153.
52. Xie Z, Lee SP, O'Dowd BF, George SR, (1999) Serotonin 5-HT1B and 5-HT1D receptors form homodimers when expressed alone and heterodimers when co-expressed. FEBS Lett 456: 63-67.
53. Herrick-Davis K, Grinde E, Harrigan TJ, Mazurkiewicz JE, (2005) Inhibition of serotonin 5-hydroxytryptamine2C receptor function through heterodimerization. J Biol Chem 280: 40144-40151.
54. Raymond JR, Olsen CL, (1994) Protein kinase a induces phosphorylation of the human 5-HT1A receptor and augments its desensitization by protein kinase c in CHO-K1 cells. Biochemistry 33: 11264-11269.
55. Yao Y, Bergold PJ, Penington NJ, (2010) Acute Ca2+-dependent desensitization of 5-HT1A receptors is mediated by activation of protein kinase a PKA in rat serotonergic neurons. Neuroscience 169: 87-97.
56. Hoyer D, Clarke DE, Fozard JR, Hartig PR, Martin GR, et al. (1994) International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin). Pharmacol Rev 46: 157-203.
57. Marg S, Walz B, Blenau W, (2004) The effects of dopamine receptor agonists and antagonists on the secretory rate of cockroach (Periplaneta americana) salivary glands. J Insect Physiol 50: 821-830.
58. Hobson RJ, Geng J, Gray AD, Komuniecki RW, (2003) SER-7b, a constitutively active Gαs coupled 5-HT7-like receptor expressed in the Caenorhabditis elegans M4 pharyngeal motorneuron. J Neurochem 87: 22-29.
59. Knight JA, Smith C, Toohey N, Klein MT, Teitler M, (2009) Pharmacological analysis of the novel, rapid, and potent inactivation of the human 5-hydroxytryptamine7 receptor by risperidone, 9-OH-risperidone, and other inactivating antagonists. Mol Pharmacol 75: 374-380.
60. Zgombick JM, Schechter LE, Adham N, Kucharewicz SA, Weinshank RL, et al. (1996) Pharmacological characterizations of recombinant human 5-HT1Dα and 5-HT1Dβ receptor subtypes coupled to adenylate cyclase inhibition in clonal cell lines: apparent differences in drug intrinsic efficacies between human 5-HT1D subtypes. Naunyn Schmiedebergs Arch Pharmacol 354: 226-236.