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Volumn 104, Issue 21, 2012, Pages 1673-1679

Dual suppression of the cyclin-dependent kinase inhibitors CDKN2C and CDKN1A in human melanoma

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 2C; PROTEIN C JUN; TRANSCRIPTION FACTOR AP 1;

EID: 84869034673     PISSN: 00278874     EISSN: 14602105     Source Type: Journal    
DOI: 10.1093/jnci/djs373     Document Type: Article
Times cited : (31)

References (31)
  • 1
    • 79959795786 scopus 로고    scopus 로고
    • Improved survival with vemurafenib in melanoma with BRAF V600E mutation
    • BRIM-3 Study Group
    • Chapman PB, Hauschild A, Robert C, et al.; BRIM-3 Study Group. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med. 2011;364(26):2507-2516.
    • (2011) N Engl J Med. , vol.364 , Issue.26 , pp. 2507-2516
    • Chapman, P.B.1    Hauschild, A.2    Robert, C.3
  • 2
    • 77956030786 scopus 로고    scopus 로고
    • Inhibition of mutated, activated BRAF in metastatic melanoma
    • Flaherty KT, Puzanov I, Kim KB, et al. Inhibition of mutated, activated BRAF in metastatic melanoma. N Engl J Med. 2010;363(9):809-819.
    • (2010) N Engl J Med. , vol.363 , Issue.9 , pp. 809-819
    • Flaherty, K.T.1    Puzanov, I.2    Kim, K.B.3
  • 3
    • 77956513286 scopus 로고    scopus 로고
    • Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma
    • Bollag G, Hirth P, Tsai J, et al. Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. Nature. 2010;467(7315):596-599.
    • (2010) Nature , vol.467 , Issue.7315 , pp. 596-599
    • Bollag, G.1    Hirth, P.2    Tsai, J.3
  • 4
    • 34248563299 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinase kinase kinases in signal integration
    • Cuevas BD, Abell AN, Johnson GL. Role of mitogen-activated protein kinase kinase kinases in signal integration. Oncogene. 2007;26(22):3159-3171.
    • (2007) Oncogene , vol.26 , Issue.22 , pp. 3159-3171
    • Cuevas, B.D.1    Abell, A.N.2    Johnson, G.L.3
  • 5
    • 78650303507 scopus 로고    scopus 로고
    • Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
    • Nazarian R, Shi H, Wang Q, et al. Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation. Nature. 2010;468(7326):973-977.
    • (2010) Nature , vol.468 , Issue.7326 , pp. 973-977
    • Nazarian, R.1    Shi, H.2    Wang, Q.3
  • 6
    • 80051625929 scopus 로고    scopus 로고
    • Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling
    • Wagle N, Emery C, Berger MF, et al. Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling. J Clin Oncol. 2011;29(22):3085-3096.
    • (2011) J Clin Oncol. , vol.29 , Issue.22 , pp. 3085-3096
    • Wagle, N.1    Emery, C.2    Berger, M.F.3
  • 7
    • 78650309875 scopus 로고    scopus 로고
    • COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
    • Johannessen CM, Boehm JS, Kim SY, et al. COT drives resistance to RAF inhibition through MAP kinase pathway reactivation. Nature. 2010;468(7326):968- 972.
    • (2010) Nature , vol.468 , Issue.7326 , pp. 968-972
    • Johannessen, C.M.1    Boehm, J.S.2    Kim, S.Y.3
  • 8
    • 78650008177 scopus 로고    scopus 로고
    • Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K
    • Villanueva J, Vultur A, Lee JT, et al. Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K. Cancer Cell. 2010;18(6):683-695.
    • (2010) Cancer Cell. , vol.18 , Issue.6 , pp. 683-695
    • Villanueva, J.1    Vultur, A.2    Lee, J.T.3
  • 9
    • 77950193693 scopus 로고    scopus 로고
    • An oncogenic role for ETV1 in melanoma
    • Jané-Valbuena J, Widlund HR, Perner S, et al. An oncogenic role for ETV1 in melanoma. Cancer Res. 2010;70(5):2075-2084.
    • (2010) Cancer Res. , vol.70 , Issue.5 , pp. 2075-2084
    • Jané-Valbuena, J.1    Widlund, H.R.2    Perner, S.3
  • 10
    • 0242691046 scopus 로고    scopus 로고
    • AP-1: A double-edged sword in tumorigenesis
    • Eferl R, Wagner EF. AP-1: a double-edged sword in tumorigenesis. Nat Rev Cancer. 2003;3(11):859-868.
    • (2003) Nat Rev Cancer. , vol.3 , Issue.11 , pp. 859-868
    • Eferl, R.1    Wagner, E.F.2
  • 11
    • 34247606483 scopus 로고    scopus 로고
    • Rewired ERK-JNK signaling pathways in melanoma
    • Lopez-Bergami P, Huang C, Goydos JS, et al. Rewired ERK-JNK signaling pathways in melanoma. Cancer Cell. 2007;11(5):447-460.
    • (2007) Cancer Cell. , vol.11 , Issue.5 , pp. 447-460
    • Lopez-Bergami, P.1    Huang, C.2    Goydos, J.S.3
  • 13
    • 0029012476 scopus 로고
    • A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death
    • Ham J, Babij C, Whitfield J, et al. A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death. Neuron. 1995;14(5):927-939.
    • (1995) Neuron. , vol.14 , Issue.5 , pp. 927-939
    • Ham, J.1    Babij, C.2    Whitfield, J.3
  • 14
    • 0035172076 scopus 로고    scopus 로고
    • Dominant negative c-jun inhibits activation of the cyclin D1 and cyclin e kinase complexes
    • Hennigan RF, Stambrook PJ. Dominant negative c-jun inhibits activation of the cyclin D1 and cyclin E kinase complexes. Mol Biol Cell. 2001;12(8):2352-2363.
    • (2001) Mol Biol Cell. , vol.12 , Issue.8 , pp. 2352-2363
    • Hennigan, R.F.1    Stambrook, P.J.2
  • 15
    • 36749068064 scopus 로고    scopus 로고
    • Genetic cooperation between p21Cip1 and INK4 inhibitors in cellular senescence and tumor suppression
    • Quereda V, Martinalbo J, Dubus P, Carnero A, Malumbres M. Genetic cooperation between p21Cip1 and INK4 inhibitors in cellular senescence and tumor suppression. Oncogene. 2007;26(55):7665-7674.
    • (2007) Oncogene , vol.26 , Issue.55 , pp. 7665-7674
    • Quereda, V.1    Martinalbo, J.2    Dubus, P.3    Carnero, A.4    Malumbres, M.5
  • 16
    • 0032784037 scopus 로고    scopus 로고
    • CDKN2A (P16(INK4a)) and CDK4 mutation analysis in 131 Australian melanoma probands: Effect of family history and multiple primary melanomas
    • Holland EA, Schmid H, Kefford RF, Mann GJ. CDKN2A (P16(INK4a)) and CDK4 mutation analysis in 131 Australian melanoma probands: effect of family history and multiple primary melanomas. Genes Chromosomes Cancer. 1999;25(4):339-348.
    • (1999) Genes Chromosomes Cancer , vol.25 , Issue.4 , pp. 339-348
    • Holland, E.A.1    Schmid, H.2    Kefford, R.F.3    Mann, G.J.4
  • 17
    • 27844567142 scopus 로고    scopus 로고
    • Distinct sets of genetic alterations in melanoma
    • Curtin JA, Fridlyand J, Kageshita T, et al. Distinct sets of genetic alterations in melanoma. N Engl J Med. 2005;353(20):2135-2147.
    • (2005) N Engl J Med. , vol.353 , Issue.20 , pp. 2135-2147
    • Curtin, J.A.1    Fridlyand, J.2    Kageshita, T.3
  • 18
    • 0029805005 scopus 로고    scopus 로고
    • Cyclin kinase inhibitor p21WAF1/CIP1 in malignant melanoma: Reduced expression in metastatic lesions
    • Maelandsmo GM, Holm R, Fodstad O, Kerbel RS, Flørenes VA. Cyclin kinase inhibitor p21WAF1/CIP1 in malignant melanoma: reduced expression in metastatic lesions. Am J Pathol. 1996;149(6):1813-1822.
    • (1996) Am J Pathol. , vol.149 , Issue.6 , pp. 1813-1822
    • Maelandsmo, G.M.1    Holm, R.2    Fodstad, O.3    Kerbel, R.S.4    Flørenes, V.A.5
  • 19
    • 13944273767 scopus 로고    scopus 로고
    • Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression
    • Carreira S, Goodall J, Aksan I, et al. Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression. Nature. 2005;433(7027):764-769.
    • (2005) Nature , vol.433 , Issue.7027 , pp. 764-769
    • Carreira, S.1    Goodall, J.2    Aksan, I.3
  • 20
    • 3142775003 scopus 로고    scopus 로고
    • Activation of protein kinase C promotes human cancer cell growth through downregulation of p18(INK4c)
    • Matsuzaki Y, Takaoka Y, Hitomi T, Nishino H, Sakai T. Activation of protein kinase C promotes human cancer cell growth through downregulation of p18(INK4c). Oncogene. 2004;23(31):5409-5414.
    • (2004) Oncogene , vol.23 , Issue.31 , pp. 5409-5414
    • Matsuzaki, Y.1    Takaoka, Y.2    Hitomi, T.3    Nishino, H.4    Sakai, T.5
  • 21
    • 33750442923 scopus 로고    scopus 로고
    • Genomewide analysis of estrogen receptor binding sites
    • Carroll JS, Meyer CA, Song J, et al. Genomewide analysis of estrogen receptor binding sites. Nat Genet. 2006;38(11):1289-1297.
    • (2006) Nat Genet. , vol.38 , Issue.11 , pp. 1289-1297
    • Carroll, J.S.1    Meyer, C.A.2    Song, J.3
  • 22
    • 0035818589 scopus 로고    scopus 로고
    • Invasive melanoma in Cdk4-targeted mice
    • Sotillo R, García JF, Ortega S, et al. Invasive melanoma in Cdk4-targeted mice. Proc Natl Acad Sci USA. 2001;98(23):13312-13317.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.23 , pp. 13312-13317
    • Sotillo, R.1    García, J.F.2    Ortega, S.3
  • 23
    • 33645510413 scopus 로고    scopus 로고
    • Spontaneous and UV radiation-induced multiple metastatic melanomas in Cdk4R24C/R24C/TPras mice
    • Hacker E, Muller HK, Irwin N, et al. Spontaneous and UV radiation-induced multiple metastatic melanomas in Cdk4R24C/R24C/TPras mice. Cancer Res. 2006;66(6):2946-2952.
    • (2006) Cancer Res. , vol.66 , Issue.6 , pp. 2946-2952
    • Hacker, E.1    Muller, H.K.2    Irwin, N.3
  • 24
    • 0032516238 scopus 로고    scopus 로고
    • Release of cell cycle constraints in mouse melanocytes by overexpressed mutant E2F1E132, but not by deletion of p16INK4A or p21WAF1/CIP1
    • Halaban R, Cheng E, Zhang Y, Mandigo CE, Miglarese MR. Release of cell cycle constraints in mouse melanocytes by overexpressed mutant E2F1E132, but not by deletion of p16INK4A or p21WAF1/CIP1. Oncogene. 1998;16(19):2489-2501.
    • (1998) Oncogene , vol.16 , Issue.19 , pp. 2489-2501
    • Halaban, R.1    Cheng, E.2    Zhang, Y.3    Mandigo, C.E.4    Miglarese, M.R.5
  • 25
    • 33644676352 scopus 로고    scopus 로고
    • Potentiation of paclitaxel-induced apoptosis by the novel cyclin-dependent kinase inhibitor NU6140: A possible role for survivin down-regulation
    • Pennati M, Campbell AJ, Curto M, et al. Potentiation of paclitaxel-induced apoptosis by the novel cyclin-dependent kinase inhibitor NU6140: a possible role for survivin down-regulation. Mol Cancer Ther. 2005;4(9):1328-1337.
    • (2005) Mol Cancer Ther. , vol.4 , Issue.9 , pp. 1328-1337
    • Pennati, M.1    Campbell, A.J.2    Curto, M.3
  • 26
    • 15444355744 scopus 로고    scopus 로고
    • CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation
    • Brooks EE, Gray NS, Joly A, et al. CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation. J Biol Chem. 1997;272(46):29207-29211.
    • (1997) J Biol Chem. , vol.272 , Issue.46 , pp. 29207-29211
    • Brooks, E.E.1    Gray, N.S.2    Joly, A.3
  • 27
    • 0033386504 scopus 로고    scopus 로고
    • The p16 status of tumor cell lines identifies small molecule inhibitors specific for cyclin-dependent kinase 4
    • Kubo A, Nakagawa K, Varma RK, et al. The p16 status of tumor cell lines identifies small molecule inhibitors specific for cyclin-dependent kinase 4. Clin Cancer Res. 1999;5(12):4279-4286.
    • (1999) Clin Cancer Res. , vol.5 , Issue.12 , pp. 4279-4286
    • Kubo, A.1    Nakagawa, K.2    Varma, R.K.3
  • 28
    • 0037573393 scopus 로고    scopus 로고
    • Synthesis, structure-activity relationship, and biological studies of indolocarbazoles as potent cyclin D1-CDK4 inhibitors
    • Zhu G, Conner SE, Zhou X, et al. Synthesis, structure-activity relationship, and biological studies of indolocarbazoles as potent cyclin D1-CDK4 inhibitors. J Med Chem. 2003;46(11):2027-2030.
    • (2003) J Med Chem. , vol.46 , Issue.11 , pp. 2027-2030
    • Zhu, G.1    Conner, S.E.2    Zhou, X.3
  • 29
    • 66149126085 scopus 로고    scopus 로고
    • Antitumor efficacy of the novel RAF inhibitor GDC- 0879 is predicted by BRAFV600E mutational status and sustained extracellular signal-regulated kinase/mitogen-activated protein kinase pathway suppression
    • Hoeflich KP, Herter S, Tien J, et al. Antitumor efficacy of the novel RAF inhibitor GDC- 0879 is predicted by BRAFV600E mutational status and sustained extracellular signal-regulated kinase/mitogen-activated protein kinase pathway suppression. Cancer Res. 2009;69(7):3042-3051.
    • (2009) Cancer Res. , vol.69 , Issue.7 , pp. 3042-3051
    • Hoeflich, K.P.1    Herter, S.2    Tien, J.3
  • 30
    • 0032984348 scopus 로고    scopus 로고
    • Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo
    • Sebolt-Leopold JS, Dudley DT, Herrera R, et al. Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo. Nat Med. 1999;5(7):810-816.
    • (1999) Nat Med. , vol.5 , Issue.7 , pp. 810-816
    • Sebolt-Leopold, J.S.1    Dudley, D.T.2    Herrera, R.3
  • 31
    • 0032552994 scopus 로고    scopus 로고
    • MEK inhibitors: The chemistry and biological activity of U0126, its analogs, and cyclization products
    • Duncia JV, Santella JB III, Higley CA, et al. MEK inhibitors: the chemistry and biological activity of U0126, its analogs, and cyclization products. Bioorg Med Chem Lett. 1998;8(20):2839-2844.
    • (1998) Bioorg Med Chem Lett. , vol.8 , Issue.20 , pp. 2839-2844
    • Duncia, J.V.1    Santella III, J.B.2    Higley, C.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.