Protective effect of Mollugo nudicaulis Lam. on acute liver injury induced by perchloroethylene in experimental rats

Asian Pacific Journal of Tropical Medicine

Volumn 5, Issue 11, 2012, Pages 862-867

  Rajamanikandan, Sundaraj ^a   Sindhu, Thangaraj ^a   Durgapriya, Dhanapal ^a   Sophia, Dominic ^a   Ragavendran, Paramasivam ^a   Gopalakrishnan, Velliyur Kanniappan ^a  

^a KARPAGAM UNIVERSITY   (India)

Author keywords

Antioxidants; Hepatoprotective activity; Histopathological studies; Mollugo nudicaulis; Perchloroethylene

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ANTIOXIDANT; ASCORBIC ACID; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CATALASE; CREATININE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; LIPID; LIVER PROTECTIVE AGENT; MOLLUGO NUDICAULIS EXTRACT; PLANT EXTRACT; SILYMARIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; UREA; URIC ACID;

ACUTE DISEASE; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG EFFECT; DRUG MECHANISM; DRUG SCREENING; FEMALE; HISTOPATHOLOGY; KIDNEY FUNCTION; LIPID PEROXIDATION; LIVER INJURY; LIVER PROTECTION; MOLLUGINACEAE; MOLLUGO NUDICAULIS; NONHUMAN; PRIORITY JOURNAL; RAT; UREA BLOOD LEVEL; URIC ACID BLOOD LEVEL;

ANIMALS; ANTIOXIDANTS; CREATININE; DRUG-INDUCED LIVER INJURY; ENZYMES; FEMALE; HISTOCYTOCHEMISTRY; LIVER; MOLLUGINACEAE; PLANT EXTRACTS; RATS; RATS, WISTAR; TETRACHLOROETHYLENE; TREATMENT OUTCOME; UREA; URIC ACID;

EID: 84869034354     PISSN: 19957645     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1995-7645(12)60161-8     Document Type: Article

References (44)

1. Meyer SA, Kulkarni AP Hepatotoxicity. Introduction to biochemical toxicology 2001, 487-490. A John Wiley & Sons Inc, New York. 3rd ed. E. Hodgson, R.C. Smart (Eds.).
2. Chatterjee TK Medicinal plants with hepatoprotective properties. Herbal options 2000, 135-137. Books & Allied (P) Ltd, Calcutta. 3rd ed.
3. Kamba AS, Hassan LG Phytochemical and microbial screening of Parkinsonia aculeata L. Leaves. Int J Drug Dev & Res 2010, 2:1-7.
4. Karan M, Vasisht K, Handa SS Antihepatotoxic activity of Swertia chirata on carbon tetrachloride induced hepatotoxicity in rats. Phytother Res 1999, 13:24-30.
5. Ahsan Md R, Islam KMM, Bulbul IJ, Musaddik Md A, Haque E Hepatoprotective activity of methanol extract of some medicinal plants against carbon tetrachloride-induced hepatotoxicity in rats. Eur J Sci Res 2009, 37:302-310.
6. Ma J, Lessner L, Schreiber J, Carpenter DO Association between residential proximity to PERC dry cleaning establishments and kidney cancer in New York city. J Environ Public Health 2009, 1:1-7.
7. Lash LH, Parker JC Hepatic and renal toxicities associated with perchloroethylene. Pharmacol Rev 2001, 53:177-208.
8. Costa C, Barbaro M, Catania S, Silvari V, Germano MP Cytotoxicity evaluation after coexposure to perchloroethylene and selected peroxidant drugs in rat hepatocytes. Toxicol Invitro 2004, 18:37-44.
9. Singh R, Jain SC, Jain R Antioxidant activity of some medicinally important arid zone plants. Asian J Exp Sci 2009, 23:215-221.
10. Ragupathy S, Steven NG, Maruthakkutti M, Velusamy B, UI-Huda MM Consensus of the 'Malasars' traditional aboriginal knowledge of medicinal plants in the Velliangiri holy hills, India. J Ethnobiol Ethnomed 2008, 4:1-14.
11. Rajamanikandan S, Sindhu T, Durgapriya D, Sophia D, Ragavendran P, Gopalakrishnan VK Radical scavenging and antioxidant activity of ethanolic extract of Mollugo nudicaulis by in vitro assays. Ind J Pharm Edu Res 2011, 45:310-316.
12. King EJ Practical clinical enzymology 1965, 83-93. Van Nostrand Reinhold Co. Ltd, London.
13. Mallory HT, Evelyn EA The determination of bilirubin with photoelectric hepatoprotective activity. Phytochemical investigations of colorimeter. J Biol Chem 1937, 119:481-485.
14. Natelson S, Scott MI, Beffa CA A rapid method for the estimation of urea in biological fluids. Am J Clin Pathol 1952, 21:275-281.
15. Caraway WI Uric acid. Standard methods of clinical chemistry 1963, 239-247. Academic Press, New York. D. Seligson (Ed.).
16. Brod J, Sirota JH The renal clearance of endogenous " creatinine" in man. J Clin Invest 1948, 27:645-654.
17. Hogberg J, Larson RE, Kristoferson A, Orrhenices S NADPH-dependent reductase solubilized from microsomes by peroxidation and its activity. Biochem Biophys Res Commun 1974, 56:836-842.
18. Misra HP, Fridovich I The role of superoxide anion in the antioxidant of epinephrine and a single assay of superoxide dismutase. J Biol Chem 1972, 247:3170-3175.
19. Lueck H Methods of enzymatic analysis 1965, Academic Press, London.
20. Rotruck JT, Pope AL, Ganther HS Selenium: Biochemical role as a component of glutathione peroxidase purification and assay. Science 1973, 179:588-590.
21. Habig WH, Pabst MJ, Jakoby WB Glutathione-S-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem 1974, 249:7130-7139.
22. Moran MS, Difierre JW, Mannervik B Levels of glutathione, glutathione reductase and glutathione-S-transferase activities in rat lung and liver. Biochem Biophys Acta 1979, 582:67-78.
23. Omaye ST, Turabull JD, Sauberlich HE Selected methods for the determination of ascorbic acid in animal cells, tissues and fluids. Method Enzymol 1979, 62:1-11.
24. Philip BK, Mumtaz MM, Latendresse JR, Mehendale HM Impact of repeated exposure on toxicity of perchloroethylene in swiss webster mice. Toxicology 2007, 232:1-14.
25. Izunya AM, Nwaopara AO, Aigbiremolen A, Odike MAC, Oaikhena GA, Bankole JK, et al. Morphological and biochemical effects of crude aqueous extract of Mangifera indica L. (Mango) stem bark on the liver in wistar rats. Res J Appl Sci Eng Technol 2010, 2:460-465.
26. 4-induced liver injury in low-protein fed rats. Phytother Res 2005, 19:341-345.
27. Girish SA, Sudhir A, Wadodkar G Avinash, Dorle K Evaluation of hepatoprotective effect of Amalkadi ghrita against carbon tetra chloride induced hepatic damage in rats. J Ethanopharmacol 2004, 90:229-232.
28. Rosen HR, Keefe EB Laboratory evaluation of the patients with signs and Symptoms of liver disease. Clinical practice of gastroenterology 1998, 812-820. Churchill Living Stone, Philadelphia. L.J. Brandt (Ed.).
29. Shaarawy SM, Tohamy AA, Elgendy SM, Elmageed ZY, Bahnasy A, Mohammed MS, et al. Protective effects of garlic and silymarin on NDEA-induced rats hepatotoxicity. Int J Biol Sci 2009, 5:549-557.
30. Oyedemi SO, Bradley G, Afolayan AJ In vitro and -vivo antioxidant activities of aqueous extract of Strychnos henningsii Gilg. Afr J Pharm Pharmacol 2010, 4:70-78.
31. Durak D, Kalender S, Uzon FG, Demir F, Kalender Y Mercury chloride induced oxidative stress in human erythrocytes and the effect of vitamin C and E in vitro. Afr J Biotechnol 2010, 9:488-495.
32. Kumar RS, Kumar KA, Murthy NV Hepatoprotective and antioxidant effects of Caesalpinia bonducella on carbon tetrachloride-induced liver injury in rats. Int J Plant Sci 2010, 1:62-68.
33. Sreepriya M, Devaki T, Balakrishnana K Apparanantham T. Effect of Indigofera tinctoria Linn. on liver antioxidant defence system during D-galactosamine/endotoxin-induced acute hepatitis in rodents. Indian J Exp Biol 2001, 39:181-184.
34. Ahmed S, Rahman A, Alam A, Saleem M, Athar M, Sultana S Evaluation of the efficacy of Lawsonia alba in the alleviation carbon tetrachloride induced - oxidative stress. J Ethnopharmacol 2000, 69:157-164.
35. Gowda S, Desai PB, Kulkarni SS, Hull VV, Math AAK, Vernekar SN Markers of renal function tests. North Am J Med Sci 2010, 2:170-173.
36. Gharib OA Effects of Kombucha on oxidative stress induced nephrotoxicity in rats. Chin Med 2009, 4:1-6.
37. Hasugawa TM, Kuroda S A new role of uric acid as antioxidant in human plasma. Jap J Clin Pathol 1989, 37:1020-1027.
38. Ghosh N, Ghosh R, Mandal V, Mandal Subhash C Recent advances in herbal medicine for treatment of liver diseases. Pharm Biol 2011, 49:970-988.
39. Bhaskar VH, Balakrishnan N Protective effects of Pergularia daemia roots against paracetamol and carbon tetrachloride-induced hepatotoxicity in rats. Pharm Biol 2010, 48:1265-1272.
40. Nirmala M, Girija K, Lakshman K, Divya T Hepatoprotective activity of Musa paradisiaca on experimental animal models. Asian Pac J Trop Biomed 2012, 2(1):11-15.
41. Nayak SS, Jain R, Sahoo AK Hepatoprotective activity of Glycosmis pentaphylla against paracetamol-induced hepatotoxicity in Swiss albino mice. Pharm Biol 2011, 49:111-117.
42. Menon BR, Rathi MA, Thirumoorthi L, Gopalakrishnan VK Potential effect of Bacopa monnieri on nitrobenzene-induced liver damage in rats. Ind J Clin Biochem 2010, 25:401-404.
43. Rathi MA, Thirumoorthi L, Sunitha M, Meenakshi P, Gurukumar D, Gopalakrishnan VK Hepatoprotective activity of Spermacoce hispida linn. extract against nitrobenzene induced hepatotoxicity in rats. J Herbal Med Toxicol 2010, 4:201-205.
44. Gurukumar D, Sonumol VM, Rathi MA, Thirumoorthi L, Meenakshi P, Gopalakrishnan VK Hepatoprotective activity of Cayratia trifolia (L.) Domin against nitrobenzene-induced hepatotoxicity. Lat Am J Pharm 2011, 30:546-549.