Pharmacogenetic markers of CYP2B6 associated with efavirenz plasma concentrations in HIV-1 infected Thai adults

British Journal of Clinical Pharmacology

Volumn 74, Issue 6, 2012, Pages 1005-1012

  Sukasem, Chonlaphat ^a,b   Cressey, Tim R ^c,d,e   Prapaithong, Pattamawan ^a   Tawon, Yardpiroon ^c   Pasomsub, Ekawat ^b   Srichunrusami, Chutatip ^b   Jantararoungtong, Thawinee ^a   Lallement, Marc ^c,d,e   Chantratita, Wasun ^b  

^a Division of Pharmacogenomics and Personalized Medicine   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

^c CHIANG MAI UNIVERSITY   (Thailand)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^e INSTITUT DE RECHERCHE POUR LE DÉVELOPPEMENT   (France)

Author keywords

CYP2B6; Efavirenz; HIV 1; Pharmacogenetics; SNPs; Thailand

Indexed keywords

CYTOCHROME P450 2B6; EFAVIRENZ;

ADULT; ARTICLE; BLOOD SAMPLING; DRUG BLOOD LEVEL; FEMALE; GENE FREQUENCY; GENOTYPE; HAPLOTYPE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MAJOR CLINICAL STUDY; MALE; PHARMACOGENETICS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ADULT; ANTI-HIV AGENTS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; ARYL HYDROCARBON HYDROXYLASES; BENZOXAZINES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; GENETIC MARKERS; GENOTYPE; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; OXIDOREDUCTASES, N-DEMETHYLATING; PHARMACOGENETICS; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; RETROSPECTIVE STUDIES; THAILAND; YOUNG ADULT;

EID: 84869010225     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2012.04288.x     Document Type: Article

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