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Volumn , Issue , 2012, Pages 351-376

Rodent models to evaluate anti-obesity drugs

Author keywords

Animal models; Anti obesity drug; Body weight; Dietary induced obesity; Food intake; Obesity

Indexed keywords

ANTIOBESITY AGENT; PEPTIDE YY [3-36]; PHENTERMINE; PHENTERMINE PLUS TOPIRAMATE; RIMONABANT; SIBUTRAMINE; TETRAHYDROLIPSTATIN; TOPIRAMATE;

EID: 84869009393     PISSN: 15572153     EISSN: 19406053     Source Type: Book Series    
DOI: 10.1007/978-1-62703-095-3_22     Document Type: Article
Times cited : (2)

References (40)
  • 1
    • 84871621668 scopus 로고    scopus 로고
    • World Health Organisation.Mar 2011
    • World Health Organisation (2011) Obesity and overweight: IFact sheet No 311. http:// www.who.int/mediacentre/factsheets/ fs311/en/index.html . Mar 2011
    • (2011) Obesity and overweight: IFact sheet , Issue.311
  • 2
    • 65349156282 scopus 로고    scopus 로고
    • Long term effectiveness of diet-plus-exercise interventions vs. diet-only interventions forweight-loss: Ia meta-analysis
    • Wu T, Gao X, Chen M, van Dam RM (2009) Long term effectiveness of diet-plus-exercise interventions vs. diet-only interventions forweight-loss: Ia meta-analysis. Obes Rev10(3):313-323
    • (2009) Obes Rev , vol.10 , Issue.3 , pp. 313-323
    • Wu, T.1    Gao, X.2    Chen, M.3    Van Dam, R.M.4
  • 3
    • 80054745693 scopus 로고    scopus 로고
    • Obesity and bariatrics for the endoscopist: Inew techniques
    • Dayyeh BK, Thompson CC (2011) Obesity and bariatrics for the endoscopist: Inew techniques.Therap Adv Gastroenterol 4(6):433-442
    • (2011) Therap Adv Gastroenterol , vol.4 , Issue.6 , pp. 433-442
    • Dayyeh, B.K.1    Thompson, C.C.2
  • 5
    • 79955644166 scopus 로고    scopus 로고
    • Hormonal interactions between gut and brain
    • Zac-Varghese S, Tan T, Bloom SR (2010)Hormonal interactions between gut and brain. Discov Med 10(55):543-552
    • (2010) Discov Med , vol.10 , Issue.55 , pp. 543-552
    • Zac-Varghese, S.1    Tan, T.2    Bloom, S.R.3
  • 7
    • 70849104324 scopus 로고    scopus 로고
    • New central targets for the treatment of obesity
    • Sargent BJ, Moore NA (2009) New central targets for the treatment of obesity. Br J Clin Pharmacol 68(6):852-860
    • (2009) Br J Clin Pharmacol , vol.68 , Issue.6 , pp. 852-860
    • Sargent, B.J.1    Moore, N.A.2
  • 8
    • 77952584236 scopus 로고    scopus 로고
    • Central and peripheral molecular targets for anti-obesity pharmacotherapy
    • Valentino MA, Lin JE, Waldman SA (2010) Central and peripheral molecular targets for anti-obesity pharmacotherapy. Clin Pharmacol Ther 87(6):652-662
    • (2010) Clin Pharmacol Ther , vol.87 , Issue.6 , pp. 652-662
    • Valentino, M.A.1    Lin, J.E.2    Waldman, S.A.3
  • 9
    • 77957754436 scopus 로고    scopus 로고
    • New approaches to the pharmacological treatment of obesity: Ican they break through the ef fi cacybarrier
    • Kennett GA, Clifton PG (2010) New approaches to the pharmacological treatment of obesity: Ican they break through the ef fi cacybarrier? Pharmacol Biochem Behav 97:63-83
    • (2010) Pharmacol Biochem Behav , vol.97 , pp. 63-83
    • Kennett, G.A.1    Clifton, P.G.2
  • 12
    • 0347824360 scopus 로고    scopus 로고
    • Differences in the central nervous system distribution and pharmacology of the mouse5-hydroxytryptamine-6 receptor compared with rat and human receptors investigated by radioligand binding, site-directed mutagenesis, and molecular modelling
    • Hirst WD, Abrahamsen B, Blaney FE, CalverAR, Aloj L, Price GW, Medhurst AD (2003)Differences in the central nervous system distribution and pharmacology of the mouse5-hydroxytryptamine-6 receptor compared with rat and human receptors investigated by radioligand binding, site-directed mutagenesis, and molecular modelling. Mol Pharmacol64(6):1295-1308
    • (2003) Mol Pharmaco , vol.164 , Issue.6 , pp. 1295-1308
    • Hirst, W.D.1    Abrahamsen, B.2    Blaney, F.E.3    Calver, A.R.4    Aloj, L.5    Price, G.W.6    Medhurst, A.D.7
  • 13
    • 33751084763 scopus 로고    scopus 로고
    • Modulation of appetite by gonadal steroid hormones
    • Asarian L, Geary N (2006) Modulation of appetite by gonadal steroid hormones. Philos TransR Soc Lond B Biol Sci 361(1471):1251-1263
    • (2006) Philos TransR Soc Lond B Biol Sci , vol.361 , Issue.1471 , pp. 1251-1263
    • Asarian, L.1    Geary, N.2
  • 14
    • 0242694039 scopus 로고    scopus 로고
    • Gender differences in the control of energy homeostasis
    • Woods SC, Gotoh K, Clegg DJ (2003) Gender differences in the control of energy homeostasis. Exp Biol Med 228:1175-1180
    • (2003) Exp Biol Med , vol.228 , pp. 1175-1180
    • Woods, S.C.1    Gotoh, K.2    Clegg, D.J.3
  • 15
    • 80052943665 scopus 로고    scopus 로고
    • The utility of animal models to evaluate novel anti-obesity agents
    • Vickers SP, Jackson HC, Cheetham SC (2011) The utility of animal models to evaluate novel anti-obesity agents. Br J Pharmacol164:1248-1262
    • (2011) Br J Pharmacol , vol.164 , pp. 1248-1262
    • Vickers, S.P.1    Jackson, H.C.2    Cheetham, S.C.3
  • 17
    • 0030860731 scopus 로고    scopus 로고
    • Comparison of the effects of sibutramine and other monoamine reuptake inhibitors on food intake in the rat
    • Jackson HC, Needham AM, Hutchins LJ, Mazurkiewicz SE, Heal DJ (1997) Comparison of the effects of sibutramine and other monoamine reuptake inhibitors on food intake in the rat. Br J Pharmacol 121:1758-1762
    • (1997) Br J Pharmacol , vol.121 , pp. 1758-1762
    • Jackson, H.C.1    Needham, A.M.2    Hutchins, L.J.3    Mazurkiewicz, S.E.4    Heal, D.J.5
  • 18
    • 77949474691 scopus 로고    scopus 로고
    • Mouse models of the metabolic syndrome
    • Dis Model Mech 3:156-16619. Panchal SK, Brown L 2011) Rodent models for metabolic syndrome research. doi: I10.1155/2011/351982
    • Kennedy AJ, Ellacott KLJ, King VL, Hasty AH (2010) Mouse models of the metabolic syndrome. Dis Model Mech 3:156-16619. Panchal SK, Brown L (2011) Rodent models for metabolic syndrome research. J Biomed Biotech. doi: I10.1155/2011/351982
    • (2010) J Biomed Biotech.
    • Kennedy, A.J.1    Ellacott, K.L.J.2    King, V.L.3    Hasty, A.H.4
  • 20
    • 61449105725 scopus 로고    scopus 로고
    • Leptin: Ia pivotal regulator of human energy homeostasis
    • Farooqi IS, O'Rahilly S (2009) Leptin: Ia pivotal regulator of human energy homeostasis. Am J Clin Nutr 89:980S-984S
    • (2009) Am J Clin Nutr , vol.89
    • Farooqi, I.S.1    O'Rahilly, S.2
  • 21
    • 79957925582 scopus 로고    scopus 로고
    • Genetic approaches to understanding human obesity
    • Ramachandrappa S, Farooqi IS (2011) Genetic approaches to understanding human obesity. J Clin Invest 121(6):2080-2086
    • (2011) J Clin Invest , vol.121 , Issue.6 , pp. 2080-2086
    • Ramachandrappa, S.1    Farooqi, I.S.2
  • 22
    • 33846041268 scopus 로고    scopus 로고
    • Lessons from leptin's molecular biology: Ipotential therapeutic actions of recombinant leptin and leptinrelated compounds
    • Correia ML, Haynes WG (2007) Lessons from leptin's molecular biology: Ipotential therapeutic actions of recombinant leptin and leptinrelated compounds. Mini Rev Med Chem 7:31-38
    • (2007) Mini Rev Med Chem , vol.7 , pp. 31-38
    • Correia, M.L.1    Haynes, W.G.2
  • 24
    • 84869072203 scopus 로고    scopus 로고
    • Animal models to study obesity and type 2 diabetes induced by diet
    • In Shafrir E (ed 2nd edn. CRC, Boca Raton, FL
    • Coskun T, Chen Y, Sindelar D, Heiman M (2007) Animal models to study obesity and type 2 diabetes induced by diet. In: IShafrir E (ed) Animals models of diabetes: Ifrontiers in research, 2nd edn. CRC, Boca Raton, FL, pp 349-357
    • (2007) Animals models of Diabetes: Ifrontiers in Research , pp. 349-357
    • Coskun, T.1    Chen, Y.2    Sindelar, D.3    Heiman, M.4
  • 25
    • 0021964280 scopus 로고
    • Nutrient intakes among selected North American populations in the Lipid Research Clinic Prevalence Study; composition of fat intake
    • Goor R, Hosking JD, Dennis BH, Graves KL, Waldman GT, Haynes SG (1985) Nutrient intakes among selected North American populations in the Lipid Research Clinic Prevalence Study; composition of fat intake. Am J Clin Nutr 41:299-311
    • (1985) Am J Clin Nutr , vol.41 , pp. 299-311
    • Goor, R.1    Hosking, J.D.2    Dennis, B.H.3    Graves, K.L.4    Waldman, G.T.5    Haynes, S.G.6
  • 28
    • 84869072202 scopus 로고    scopus 로고
    • Effect of the MCH 1 antagonist, GW803430, on body weight, food and water intake, glucose tolerance, fat pad weight, ex vivo binding and various plasma parameters in dietary-induced obese C57BL/6J mice
    • DC: ISociety for Neuroscience, Online
    • Cheetham SC, Dickinson K, Goddard S, Guzzo P, Surman M, Tiong S, Xie D, Vickers S (2008) Effect of the MCH 1 antagonist, GW803430, on body weight, food and water intake, glucose tolerance, fat pad weight, ex vivo binding and various plasma parameters in dietary-induced obese C57BL/6J mice. Program No. 584.24. 2008 Neuroscience Meeting Planner, Washington, DC: ISociety for Neuroscience, Online
    • (2008) Program No.584.24. 2008 Neuroscience Meeting Planner, Washington
    • Cheetham, S.C.1    Dickinson, K.2    Goddard, S.3    Guzzo, P.4    Surman, M.5    Tiong, S.6    Xie, D.7    Vickers, S.8
  • 29
    • 51849146897 scopus 로고    scopus 로고
    • Global burden of obesity in 2005 and projections to 2030
    • Kelly T, Yang W, Chen CS, Reynolds K, He J (2008) Global burden of obesity in 2005 and projections to 2030. Int J Obesity 32(9):1431-1437
    • (2008) Int J Obesity , vol.32 , Issue.9 , pp. 1431-1437
    • Kelly, T.1    Yang, W.2    Chen, C.S.3    Reynolds, K.4    He, J.5
  • 30
    • 33749643580 scopus 로고    scopus 로고
    • Evaluation of a simpli fi ed cafeteria model for the induction of insulin resistant obesity in rats
    • Dickinson K, North TJ, Anthony DM, Jones RB, Heal DJ (1998) Evaluation of a simpli fi ed cafeteria model for the induction of insulin resistant obesity in rats. Int J Obesity 22(Suppl 3):S179
    • (1998) Int J Obesity , vol.22 , Issue.SUPPL. 3
    • Dickinson, K.1    North, T.J.2    Anthony, D.M.3    Jones, R.B.4    Heal, D.J.5
  • 31
    • 84871619672 scopus 로고    scopus 로고
    • Comparison of the effects of sibutramine and orlistat on body weight, food and water intake and body composition in dietary-induced obese rats
    • San Diego, CA: ISociety for Neuroscience, Online
    • Jackson HC, Dickinson K, Jones RB, Schumacher C, Jensen C (2004) Comparison of the effects of sibutramine and orlistat on body weight, food and water intake and body composition in dietary-induced obese rats. Program No. 75.3. 2004 Neuroscience Meeting Planner, San Diego, CA: ISociety for Neuroscience, Online
    • Program No. 2004 75.3. 2004 Neuroscience Meeting Planner
    • Jackson, H.C.1    Dickinson, K.2    Jones, R.B.3    Schumacher, C.4    Jensen, C.5
  • 34
    • 77957754120 scopus 로고    scopus 로고
    • Behavioural satiety sequence (BSS): Iseparating wheat from chaff in the behavioural pharmacology of appetite
    • Rodgers RJ, Holch P, Tallett AJ (2010) Behavioural satiety sequence (BSS): Iseparating wheat from chaff in the behavioural pharmacology of appetite. Pharmacol Biochem Behav 97(1):3-14
    • (2010) Pharmacol Biochem Behav , vol.97 , Issue.1 , pp. 3-14
    • Rodgers, R.J.1    Holch, P.2    Tallett, A.J.3
  • 35
    • 80053319540 scopus 로고    scopus 로고
    • Observational analysis of the effects of sibutramine, phentermine and aminorex on food intake in rats
    • Jackson HC, Pleasance IM, Mitchell JM, Heal DJ (2000) Observational analysis of the effects of sibutramine, phentermine and aminorex on food intake in rats. Obes Res 8(Suppl 1):95S
    • (2000) Obes Res , vol.8 , Issue.SUPPL. 1
    • Jackson, H.C.1    Pleasance, I.M.2    Mitchell, J.M.3    Heal, D.J.4
  • 36
    • 34948850289 scopus 로고    scopus 로고
    • Grooming, scratching and feeding: Irole of response competition in acute anorectic response to rimonabant in male rats
    • Tallett AJ, Blundell JE, Rodgers RJ (2007) Grooming, scratching and feeding: Irole of response competition in acute anorectic response to rimonabant in male rats. Psychopharmacology 195(1):27-39
    • (2007) Psychopharmacology , vol.195 , Issue.1 , pp. 27-39
    • Tallett, A.J.1    Blundell, J.E.2    Rodgers, R.J.3
  • 37
    • 84869061803 scopus 로고    scopus 로고
    • Weight loss induced by the potent and selective SGLT-2 inhibitor, BI 10773, is due to body fat reduction
    • Poster No: I1793-P, American Diabetes Association 70th Scienti fi c Sessions, Orlando, FL, 25-29 June 2010, Online
    • Grempler R, Thomas L, Klein T, Mark M, Jackson H, Cheetham S, Eickelmann P (2010) Weight loss induced by the potent and selective SGLT-2 inhibitor, BI 10773, is due to body fat reduction: IStudies in dietary-induced obese rats. Poster No: I1793-P, American Diabetes Association 70th Scienti fi c Sessions, Orlando, FL, 25-29 June 2010, Online
    • (2010) IStudies in dietary-induced obese rats
    • Grempler, R.1    Thomas, L.2    Klein, T.3    Mark, M.4    Jackson, H.5    Cheetham, S.6    Eickelmann, P.7
  • 38
    • 0033036174 scopus 로고    scopus 로고
    • Thermogenic effects of sibutramine and its metabolites
    • Skill M.J.Dickinson K, Jones RB, Heal D.J. 2000 effect of repeated sibutramine treatment in female Wistar rats. Int J Obesity 24(Suppl 1 S135
    • Connoley IP, Liu YL, Frost I, Reckless IP, Heal DJ, Stock MJ (1999) Thermogenic effects of sibutramine and its metabolites. Br J Pharmacol 126(6):1487-149540. Skill MJ, Dickinson K, Jones RB, Heal DJ (2000) Thermogenic effect of repeated sibutramine treatment in female Wistar rats. Int J Obesity 24(Suppl 1):S135
    • (1999) Br J Pharmacol , vol.126 , Issue.6 , pp. 1487-1495
    • Connoley, I.P.1    Liu, Y.L.2    Frost, I.3    Reckless, I.P.4    Heal, D.J.5    Stock, M.J.6
  • 39
    • 33847351602 scopus 로고    scopus 로고
    • Effects of sibutramine on thermogenesis in obese patients assessed via immersion calorimetry
    • Saraç F, Pehlivan M, Celebi G, Saygili F, Yilmaz C, Kabalak T (2006) Effects of sibutramine on thermogenesis in obese patients assessed via immersion calorimetry. Adv Ther 23(6):1016-1029
    • (2006) Adv Ther , vol.23 , Issue.6 , pp. 1016-1029
    • Saraç, F.1    Pehlivan, M.2    Celebi, G.3    Saygili, F.4    Yilmaz, C.5    Kabalak, T.6


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