Non-invasive collection of exhaled breath condensate in rats: Evaluation of pH, H2O2 and NOx in lipopolysaccharide-induced acute lung injury

Veterinary Journal

Volumn 194, Issue 2, 2012, Pages 222-228

  de Broucker, Virginie ^a,b   Hassoun, Sidi Mohamed ^a   Hulo, Sébastien ^a,b   Chérot Kornobis, Nathalie ^a,b   Nevière, Rémi ^b,c   Matran, Régis ^a,b   Sobaszek, Annie ^a,b   Edme, Jean Louis ^a,b  

^a UFR3S Pharmacie   (France)

^b LILLE UNIVERSITY HOSPITAL   (France)

^c UNIV LILLE   (France)

Author keywords

Exhaled breath condensate; Hydrogen peroxide; Nitrogen oxides; Non invasive; PH

Indexed keywords

BIOLOGICAL MARKER; HYDROGEN PEROXIDE; LIPOPOLYSACCHARIDE; NITROGEN OXIDE;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ARTICLE; BREATH ANALYSIS; CONTROLLED STUDY; DISEASE MARKER; ENVIRONMENTAL PARAMETERS; ENVIRONMENTAL TEMPERATURE; EXHALED BREATH CONDENSATE FLUID; HUMIDITY; INFLAMMATION; MALE; NON INVASIVE PROCEDURE; NONHUMAN; OXIDATIVE STRESS; PH; RAT;

ANIMALS; BREATH TESTS; BRONCHOALVEOLAR LAVAGE FLUID; ENDOTOXEMIA; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; HYDROGEN PEROXIDE; HYDROGEN-ION CONCENTRATION; INFLAMMATION; LIPOPOLYSACCHARIDES; LUNG DISEASES; MALE; NITROGEN OXIDES; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATORY SYSTEM; SPECIMEN HANDLING;

ANIMALIA; RATTUS;

EID: 84868699755     PISSN: 10900233     EISSN: 15322971     Source Type: Journal    
DOI: 10.1016/j.tvjl.2012.04.009     Document Type: Article

References (37)

1. Ader F., Le Berre R., Lancel S., Faure K., Viget N.B., Nowak E., Nevière R., Guery B.P. Inhaled nitric oxide increases endothelial permeability in Pseudomonas aeruginosa pneumonia. Intensive Care Medicine 2007, 33:503-510.
2. Bondesson E., Jansson L.T., Bengtsson T., Wollmer P. Exhaled breath condensate-site and mechanisms of formation. Journal of Breath Research 2009, 3:016005.
3. Bosma K., Fanelli V., Ranieri V.M. Acute respiratory distress syndrome: Update on the latest developments in basic and clinical research. Current Opinion in Anaesthesiology 2005, 18:137-145.
4. Chen H.I., Yeh D.Y., Liou H.L., Kao S.J. Insulin attenuates endotoxininduced acute lung injury in conscious rats. Critical Care Medicine 2006, 34:758-764.
5. Cherot-Kornobis N., Hulo S., Edme J.L., de Broucker V., Matran R., Sobaszek A. Analysis of nitrogen oxides (NOx) in the exhaled breath condensate (EBC) of subjects with asthma as a complement to exhaled nitric oxide (FeNO) measurements: A cross-sectional study. BMC Research Notes 2011, 4:202.
6. Corradi M., Alinovi R., Goldoni M., Vettori M., Folesani G., Mozzoni P., Cavazzini S., Bergamaschi E., Rossi L., Mutti A. Biomarkers of oxidative stress after controlled human exposure to ozone. Toxicology Letters 2002, 134:219-225.
7. Deaton C.M., Marlin D.J., Newton R., Smith K.C., Schroter R. Expired breath condensate hydrogen peroxide correlates with bronchoalveolar lavage neutrophilia. European Respiratory Journal 2003, 22:18.
8. Deaton C.M., Marlin D.J., Smith N.C., Harris P.A., Dagleish M.P., Schroter R.C., Kelly F.J. Effect of acute airway inflammation on the pulmonary antioxidant status. Experimental Lung Research 2005, 31:653-670.
9. Duz M., Whittaker A.G., Love S., Parkin T.D.H., Hughes K.J. Exhaled breath condensate hydrogen peroxide and pH for the assessment of lower airway inflammation in the horse. Research in Veterinary Science 2009, 87:307-312.
10. Gessner C., Hammerschmidt S., Kuhn H., Seyfarth H.J., Sack U., Engelmann L., Schauer J., Wirtz H. Exhaled breath condensate acidification in acute lung injury. Respiratory Medicine 2003, 97:1188-1194.
11. Hatt J.M., Zollinger E., Boehler A., Hofer M., Steinmetz H.W., Clauss M. Collection and analysis of breath and breath condensate exhaled by feral pigeons (Columba livia) and chickens (Gallus domesticus). Veterinary Record 2009, 165:469-473.
12. 2 production in rats. Experimental Lung Research 2003, 29:585-592.
13. Horváth I., Donnelly L.E., Kiss A., Paredi P., Kharitonov S.A., Barnes P.J. Raised levels of exhaled carbon monoxide are associated with an increased expression of heme oxygenase-1 in airway macrophages in asthma: A new marker of oxidative stress. Thorax 1998, 53:668-672.
14. Horváth I., Hunt J., Barnes P.J., Alving K., Antczak A., Baraldi E., Becher G., van Beurden W.J.C., Corradi M., Dekhuijzen R., Dweik R.A., Dwyer T., Effros R., Erzurum S., Gaston B., Gessner C., Greening A., Ho L.P., Hohlfeld J., Jöbsis Q., Laskowski D., Loukides S., Marlin D., Montuschi P., Olin A.C., Redington A.E., Reinhold P., van Rensen E.L.J., Rubinstein I., Silkoff P., Toren K., Vass G., Vogelberg C., Wirtz H. Exhaled breath condensate: Methodological recommendations and unresolved questions. The European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology 2005, 26:523-548.
15. Jakubowski A. S-nitroso-human-albumin: A new therapeutic approach in endotoxic shock. Polskie Archiwum Medycyny Wewnetrznej 2009, 119:501-504.
16. Kirschvink N., Marlin D., Delvaux F., Leemans J., Clercx C., Sparkes A., Gustin P. Collection of exhaled breath condensate and analysis of hydrogen peroxide as a potential marker of lower airway inflammation in cats. The Veterinary Journal 2005, 169:385-396.
17. 2 and pH in exhaled breath condensate samples: Methodical and physiological aspects. Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals 2008, 13:319-341.
18. Lee R.P., Wang D., Lin N.T., Chen H.I. Physiological and chemical indicators for early and late stages of sepsis in conscious rats. Journal of Biomedical Science 2002, 9:613-621.
19. Lee W.L., Slutsky A.S. Sepsis and endothelial permeability. New England Journal of Medicine 2010, 363:689-691.
20. Leung T.F., Li C.Y., Yung E., Liu E.K.H., Lam C.W.K., Wong G.W.K. Clinical and technical factors affecting pH and other biomarkers in exhaled breath condensate. Pediatric Pulmonology 2006, 41:87-94.
21. Li X.C., Miyasaka M., Issekutz T.B. Blood monocyte migration to acute lung inflammation involves both CD11/CD18 and very late activation antigen-4-dependent and independent pathways. Journal of Immunology 1998, 161:6258-6264.
22. Liu L., Teague W.G., Erzurum S., Fitzpatrick A., Mantri S., Dweik R.A., Bleecker E.R., Meyers D., Busse W.W., Calhoun W.J., Castro M., Chung K.F., Curran-Everett D., Israel E., Jarjour W.N., Moore W., Peters S.P., Wenzel S., Hunt J.F., Gaston B. Determinants of exhaled breath condensate pH in a large population with asthma. Chest 2011, 139:328-336.
23. Maple C., Kirk G., McLaren M., Veale D., Belch J.J. A circadian variation exists for soluble levels of intercellular adhesion molecule-1 and E-selectin in healthy volunteers. Clinical Science (London, England: 1979) 1998, 94:537-540.
24. Möller W., Heimbeck I., Weber N., Saba G.K., Körner B., Neiswirth M., Kohlhäufl M. Fractionated exhaled breath condensate collection shows high hydrogen peroxide release in the airways. Journal of Aerosol Medicine and Pulmonary Drug Delivery 2010, 23:129-135.
25. Nicolaou N.C., Lowe L.A., Murray C.S., Woodcock A., Simpson A., Custovic A. Exhaled breath condensate pH and childhood asthma: Unselected birth cohort study. American Journal of Respiratory and Critical Care Medicine 2006, 174:254-259.
26. 2 and thiobarbituric acid reactive substances (TBARs) by healthy subjects. Free Radical Biology and Medicine 2001, 30:178-186.
27. Paget-Brown A.O., Ngamtrakulpanit L., Smith A., Bunyan D., Hom S., Nguyen A., Hunt J.F. Normative data for pH of exhaled breath condensate. Chest 2006, 129:426-430.
28. Pauluhn J. Mosquito coil smoke inhalation toxicity. Part I: Validation of test approach and acute inhalation toxicity. Journal of Applied Toxicology 2006, 26:269-278.
29. Prince P., Boulay M.E., Boulet L.P. A fast, simple, and inexpensive method to collect exhaled breath condensate for pH determination. Annals of Allergy, Asthma and Immunology: Official Publication of the American College of Allergy, Asthma and Immunology 2006, 97:622-627.
30. Reinhold P., Knobloch H. Exhaled breath condensate: Lessons learned from veterinary medicine. Journal of Breath Research 2010, 4:017001.
31. Reinhold P., Kirschvink N., Theegarten D., Berndt A. An experimentally induced Chlamydia suis infection in pigs results in severe lung function disorders and pulmonary inflammation. Veterinary Research 2008, 39:35.
32. Romon M., Edme J.L., Boulenguez C., Lescroart J.L., Frimat P. Circadian variation of diet-induced thermogenesis. The American Journal of Clinical Nutrition 1993, 57:476-480.
33. Sparkes A.H., Mardell E.J., Deaton C., Kirschvink N., Marlin D. Exhaled breath condensate (EBC) collection in cats - Description of a non-invasive technique to investigate airway disease. Journal of Feline Medicine and Surgery 2004, 6:335-338.
34. Webster M.D., King J.R. Temperature and humidity dynamics of cutaneous and respiratory evaporation in pigeons, Columba livia. Journal of Comparative Physiology, B: Biochemical, Systemic, and Environmental Physiology 1987, 157:253-260.
35. Weissmann N., Vogels H., Schermuly R.T., Ghofrani H.A., Hänze J., Fink L., Rose F., Seeger W., Grimminger F. Measurement of exhaled hydrogen peroxide from rabbit lungs. Biological Chemistry 2004, 385:259-264.
36. Wilhelm J., Frydrychová M., Vízek M. Hydrogen peroxide in the breath of rats: The effects of hypoxia and paraquat. Physiological Research 1999, 48:445-449.
37. Wilhelm J., Vanková M., Maxová H., Sisková A. Hydrogen peroxide production by alveolar macrophages is increased and its concentration is elevated in the breath of rats exposed to hypoxia: Relationship to lung lipid peroxidation. Physiological Research/Academia Scientiarum Bohemoslovaca 2003, 52:327-332.