Exhaled breath condensate hydrogen peroxide and pH for the assessment of lower airway inflammation in the horse

Research in Veterinary Science

Volumn 87, Issue 2, 2009, Pages 307-312

  Duz, M ^a   Whittaker, A G ^a   Love, S ^a   Parkin, T D H ^a,b   Hughes, K J ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Exhaled breath condensate; Horse; Hydrogen peroxide; Lower airway inflammation; pH

Indexed keywords

HYDROGEN PEROXIDE;

ARTICLE; BREATH ANALYSIS; CONTROLLED STUDY; EXPIRED AIR; HORSE DISEASE; LOWER RESPIRATORY TRACT; LUNG LAVAGE; MALE; NONHUMAN; PH; RESPIRATORY TRACT INFLAMMATION;

AIRWAY OBSTRUCTION; ANIMALS; BREATH TESTS; BRONCHOALVEOLAR LAVAGE FLUID; EXHALATION; HORSE DISEASES; HORSES; HYDROGEN PEROXIDE; HYDROGEN-ION CONCENTRATION; INFLAMMATION;

EQUIDAE;

EID: 67650429713     PISSN: 00345288     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rvsc.2009.03.014     Document Type: Article

References (34)

1. Antczak A., Kurmanowska Z., Kasielski M., and Nowak D. Inhaled glucocorticosteroids decrease hydrogen peroxide level in expired air condensate in asthmatic patients. Respir. Med. 94 (2000) 416-421
2. Babior B.M. Phagocytes and oxidative stress. Am. J. Med. 109 (2000) 33-44
3. Borrill Z., Starkey C., Vestbo J., and Singh D. Reproducibility of exhaled breath condensate pH in chronic obstructive pulmonary disease. Eur. Respir. J. 25 (2005) 269-274
4. Brunetti L., Francavilla R., Tesse R., Strippoli A., Polimeno L., Loforese A., Miniello V.L., and Armenio L. Exhaled breath condensate pH measurement in children with asthma, allergic rhinitis and atopic dermatitis. Pediatr. Allergy Immunol. 17 (2006) 422-427
5. Couetil L.L., Hoffman A.M., Hodgson J., Buechner-Maxwell V., Viel L., Wood J.L., and Lavoie J.P. Inflammatory airway disease of horses. J. Vet. Intern. Med. 21 (2007) 356-361
6. Deaton C.M., Marlin D.J., Smith N.C., Harris P.A., Roberts C.A., Schroter R.C., and Kelly F.J. Pulmonary epithelial lining fluid and plasma ascorbic acid concentrations in horses affected by recurrent airway obstruction. Am. J. Vet. Res. 65 (2004) 80-87
7. Deaton C.M., Marlin D.J., Smith N.C., Smith K.C., Newton R.J., Gower S.M., Cade S.M., Roberts C.A., Harris P.A., Schroter R.C., and Kelly F.J. Breath condensate hydrogen peroxide correlates with both airway cytology and epithelial lining fluid ascorbic acid concentration in the horse. Free Radic. Res. 38 (2004) 201-208
8. Deaton C.M., Marlin D.J., Smith N.C., Harris P.A., Dagleish M.P., Schroter R.C., and Kelly F.J. Effect of acute airway inflammation on the pulmonary antioxidant status. Exp. Lung Res. 31 (2005) 653-670
9. Dixon P.M., Railton D.I., and McGorum B.C. Equine pulmonary disease: a case control study of 300 referred cases. Part 2: Details of animals and of historical and clinical findings. Equine Vet. J. 27 (1995) 422-427
10. Fireman E., Shtark M., Priel I.E., Shiner R., Mor R., Kivity S., and Fireman Z. Hydrogen Peroxide in Exhaled Breath Condensate (EBC) vs Eosinophil Count in Induced Sputum (IS) in Parenchymal vs Airways Lung Diseases. Inflammation 30 (2007) 44-51
11. 2 and 3,3′,5,5′-tetramethylbenzidine. J. Clin. Chem. Clin. Biochem. 23 (1985) 453-460
12. Hanazawa T., Kharitonov S.A., and Barnes P.J. Increased nitrotyrosine in exhaled breath condensate of patients with asthma. Am. J. Respir. Crit. Care Med. 162 (2000) 1273-1276
13. Ho L.P., Faccenda J., Innes J.A., and Greening A.P. Expired hydrogen peroxide in breath condensate of cystic fibrosis patients. Eur. Respir. J. 13 (1999) 103-106
14. Horvath I., Hunt J., and Barnes P.J. Exhaled breath condensate: methodological recommendations and unresolved questions. Eur. Respir. J. 26 (2005) 523-548
15. Hunt J.F., Fang K., Malik R., Snyder A., Malhotra N., Platts-Mills T.A., and Gaston B. Endogenous airway acidification. Implications for asthma pathophysiology. Am. J. Respir. Crit. Care Med. 161 (2000) 694-699
16. Jobsis Q., Raatgeep H.C., Hermans P.W., and de Jongste J.C. Hydrogen peroxide in exhaled air is increased in stable asthmatic children. Eur. Respir. J. 10 (1997) 519-521
17. Kostikas K., Papatheodorou G., Ganas K., Psathakis K., Panagou P., and Loukides S. PH in expired breath condensate of patients with inflammatory airway diseases. Am. J. Respir. Crit. Care Med. 165 (2002) 1364-1370
18. Lavoie J.P. Recurrent airway obstruction (heaves) and summer-pasture-associated obstructive pulmonary disease. In: McGorum B.C., Dixon P.M., Robinson N.E., and Schumacher J. (Eds). Equine Respiratory Medicine and Surgery (2007), Elsevier, Philadelphia 565-589
19. Leung T.F., Li C.Y., Yung E., Liu E.K., Lam C.W., and Wong G.W. Clinical and technical factors affecting pH and other biomarkers in exhaled breath condensate. Pediatr. Pulmonol. 41 (2006) 87-94
20. Loukides S., Horvath I., Wodehouse T., Cole P.J., and Barnes P.J. Elevated levels of expired breath hydrogen peroxide in bronchiectasis. Am. J. Respir. Crit. Care Med. 158 (1998) 991-994
21. Loukides S., Bouros D., Papatheodorou G., Panagou P., and Siafakas N.M. The relationships among hydrogen peroxide in expired breath condensate, airway inflammation, and asthma severity. Chest 121 (2002) 338-346
22. McGorum B.C., and Dixon P.M. Evaluation of local endobronchial antigen challenges in the investigation of equine chronic obstructive pulmonary disease. Equine Vet. J. 25 (1993) 269-272
23. McGorum B.C., Dixon P.M., and Halliwell R.E. Responses of horses affected with chronic obstructive pulmonary disease to inhalation challenges with mould antigens. Equine Vet. J. 25 (1993) 261-267
24. Niimi A., Nguyen L.T., Usmani O., Mann B., and Chung K.F. Reduced pH and chloride levels in exhaled breath condensate of patients with chronic cough. Thorax 59 (2004) 608-612
25. 2 and thiobarbituric acid reactive substances (TBARs) by healthy subjects. Free Radic. Biol. Med. 30 (2001) 178-186
26. Pirie R.S., Dixon P.M., Collie D.D., and McGorum B.C. Pulmonary and systemic effects of inhaled endotoxin in control and heaves horses. Equine Vet. J. 33 (2001) 311-318
27. Pirie R.S., Collie D.D., Dixon P.M., and McGorum B.C. Inhaled endotoxin and organic dust particulates have synergistic proinflammatory effects in equine heaves (organic dust-induced asthma). Clin. Exp. Allergy 33 (2003) 676-683
28. Robinson N.E. International workshop on equine chronic airway disease. Michigan State University 16-18 June 2000. Equine Vet. J. 33 (2001) 5-19
29. Schleiss M.B., Holz O., Behnke M., Richter K., Magnussen H., and Jorres R.A. The concentration of hydrogen peroxide in exhaled air depends on expiratory flow rate. Eur. Respir. J. 16 (2000) 1115-1118
30. Soyer O.U., Dizdar E.A., Keskin O., Lilly C., and Kalayci O. Comparison of two methods for exhaled breath condensate collection. Allergy 61 (2006) 1016-1018
31. Sweeney C.R., Rossier Y., Ziemer E.L., and Lindborg S.R. Effect of prior lavage on bronchoalveolar lavage fluid cell population of lavaged and unlavaged lung segments in horses. Am. J. Vet. Res. 55 (1994) 1501-1504
32. van Beurden W.J., Dekhuijzen P.N., Harff G.A., and Smeenk F.W. Variability of exhaled hydrogen peroxide in stable COPD patients and matched healthy controls. Respiration 69 (2002) 211-216
33. Vaughan J., Ngamtrakulpanit L., Pajewski T.N., Turner R., Nguyen T.A., Smith A., Urban P., Hom S., Gaston B., and Hunt J. Exhaled breath condensate pH is a robust and reproducible assay of airway acidity. Eur. Respir. J. 22 (2003) 889-894
34. Wyse C.A., Skeldon K., Hotchkiss J.W., Gibson G., Yam P.S., Christley R.M., Preston T., Cumming D.R., Padgett M., Cooper J.C., and Love S. Effects of changes to the stable environment on the exhalation of ethane, carbon monoxide and hydrogen peroxide by horses with respiratory inflammation. Vet. Rec. 157 (2005) 408-412