Cyclooxygenase inhibitory properties of nor -neolignans from Styrax pohlii

Natural Product Research

Volumn 26, Issue 24, 2012, Pages 2323-2329

  Bertanha, Camila S ^a   Braguine, Caio G ^a   Moraes, Ana C G ^a   Gimenez, Valéria M M ^b   Groppo, Milton ^c   Silva, Márcio L A ^a   Cunha, Wilson R ^a   Januário, Ana H ^a   Pauletti, Patrcia M ^a  

^a UNIVERSIDADE DE FRANCA   (Brazil)

^b Centro Univ Claretiano CEUCLAR   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

cyclooxygenase 1 2 inhibitory activity; Styracaceae; Styrax pohlii

Indexed keywords

ACETIC ACID DERIVATIVE; ALCOHOL; CYCLOOXYGENASE 1; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; EGONOL; EGONOL GENTIOBIOSIDE; HEXANE; HOMOEGONOL; HOMOEGONOL GENTIOBIOSIDE; HOMOEGONOL GLUCOSIDE; IBUPROFEN; PLANT EXTRACT; STYRAX POHLII EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; ENZYME INHIBITION; IC 50; PROSTAGLANDIN SYNTHESIS INHIBITION; STRUCTURE ANALYSIS; STYRACACEAE; STYRAX POHLII;

BENZOFURANS; BRAZIL; CYCLOOXYGENASE INHIBITORS; DISACCHARIDES; ETHANOL; GLUCOSIDES; HEXANES; LIGNANS; MOLECULAR STRUCTURE; PLANT EXTRACTS; STYRAX;

STYRACACEAE; STYRAX POHLII;

EID: 84868679569     PISSN: 14786419     EISSN: 14786427     Source Type: Journal    
DOI: 10.1080/14786419.2012.671320     Document Type: Article

References (25)

1. Anil, H. 1980. Four benzofuran glycosides from Styrax officinalis. Phytochemistry, 19: 2784-2786.
2. 2 production by taiwanin C isolated from the root of Acanthopanax chiisanensis and the mechanism of action. Biochemical Pharmacology, 64: 1345-1354. (Pubitemid 35248252)
3. 4 formation invitro. Bioorganic & Medicinal Chemistry, 18: 2809-2815.
4. Chandrasekharan, NV, Dai, H, Roos, KLT, Evanson, NK, Tomsik, J, Elton, TS, and, Simmons, DL. 2002. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression. Proceedings of the National Academy of Science of the United States of America, 99: 13926-13931. (Pubitemid 35215482)
5. Coimbra, HS, Royo, VA, de Souza, VA, Pereira, AC, de Souza, GH, da Silva, R, and, Bastos, JK. 2004. Analgesic and anti-inflammatory activities of (-)-O-benzyl cubebin, (-)-cubebin derivative, obtained by partial synthesis. Bolletino Chimico Farmaceutico, 143: 65-69.
6. Coy, ED, Cuca, LE, and, Sefkow, M. 2009. COX, LOX and platelet aggregation inhibitory properties of Lauraceae neolignans. Bioorganic & Medicinal Chemistry Letters, 19: 6922-6925.
7. Gautam, R, Srivastava, A, Jachak, SM, and, Saklani, A. 2010. Anti-inflammatory, cyclooxygenase (COX)-2, COX-1 inhibitory and antioxidant effects of Dysophylla stellata Benth. Fitoterapia, 81: 45-49.
8. Hopkins, CY, Ewing, DF, and, Chisholm, MJ. 1967. Egonol. Spectrometric properties and derivatives. Canadian Journal of Chemistry, 45: 1425-1429.
9. Hirano, T, Gotoh, M, and, Oka, K. 1994. Natural avonoids and lignans are potent cytostatic agents against human leukemic HL-60 cells. Life Sciences, 55: 1061-1069.
10. Lorenzi, H. 1998. rvores Brasileiras I, Nova Odessa, Brazil: Plantarum.
11. Min, BS, Oh, SR, Ahn, KS, Kim, JH, Lee, J, Kim, DY, and, Lee, HK. 2004. Anti-complement activity of nor-lignans and terpenes from the stem bark of Styrax japonica. Planta Medica, 70: 1210-1215. (Pubitemid 40101105)
12. Neto, AG, Costa, JM, Belati, CC, Vinhólis, AH, Possebom, LS, Da Silva Filho, AA, and, Silva, ML. 2005. Analgesic and anti-inflammatory activity of a crude root extract of Pfaffia glomerata (Spreng.) Pedersen. Journal of Ethnopharmacology, 96: 87-91. (Pubitemid 39575035)
13. Ztrk, SE, Akgl, Y, and, Anil, H. 2008. Synthesis and antibacterial activity of egonol derivatives. Bioorganic & Medicinal Chemistry, 16: 4431-4437. (Pubitemid 351539036)
14. Pauletti, PM, Arajo, AR, Young, MCM, and, Bolzani, VS. 2002. Triterpenos de Styrax camporum (Styracaceae). Quimica Nova, 25: 349-352.
15. Pauletti, PM, Arajo, AR, Young, MCM, Giesbrecht, AM, and, Bolzani, VD. 2000. nor-Lignans from the leaves of Styrax ferrugineus (Styracaceae) with antibacterial and antifungal activity. Phytochemistry, 55: 597-601.
16. Pauletti, PM, Teles, HL, Silva, DHS, Arajo, AR, and, Bolzani, VS. 2006. The Styracaceae. Revista Brasileira de Farmacognosia, 16: 576-590.
17. Rodrigues, VEG, and, de Carvalho, DA. 2008. Florstica de plantas medicinais nativas de remanescentes de floresta estacional semidecidual na regio do alto rio Grande, Minas Gerais. Cerne, 14: 93-112. (Pubitemid 352007462)
18. Schreiber, FG, and, Stevenson, R. 1976. Synthesis of benzofuran Styrax extratives. Journal of the Chemical Society, Perkin Transactions, 14: 1514-1518.
19. Smith, WL, DeWitt, DL, and, Garavito, RM. 2000. Cyclooxygenases: Structural, cellular, and molecular biology. Annual Review of Biochemistry, 69: 145-182.
20. Su, BN, Jones, WP, Cuendet, M, Kardono, LB, Ismail, R, Riswan, S, and, Kinghorn, AD. 2004. Constituents of the stems of Macrococculus pomiferus and their inhibitory activities against cyclooxygenases-1 and-2. Phytochemistry, 65: 2861-2866. (Pubitemid 40292117)
21. Takanashi, M, and, Takizawa, Y. 2002. Isolation of new egonol compounds from seeds of Styrax japonica Sieb. Et Zucc. Journal of Oleo Science, 51: 151-155.
22. Teles, HL, Hemerly, JP, Pauletti, PM, Pandolfi, JRC, Arajo, AR, Valentini, SR, and, Silva, DHS. 2005. Cytotoxic lignans from the stems of Styrax camporum (Styracaceae). Natural Products Research, 19: 319-323. (Pubitemid 40716083)
23. Tzeng, S-C, and, Liu, Y-C. 2004. Peroxidase-catalyzed synthesis of neolignan and its anti-inflammatory activity. Journal of Molecular Catalysis B: Enzymatic, 32: 7-13. (Pubitemid 39572632)
24. Vasconcelos, MA, Royo, VA, Ferreira, DS, Crotti, AE, Andrade e Silva, ML, Carvalho, JC, and, Cunha, WR. 2006. Invivo analgesic and anti-inflammatory activities of ursolic acid and oleanoic acid from Miconia albicans (Melastomataceae). Zeitschrift fr Naturforschung C, 61: 477-482. (Pubitemid 44367440)
25. Warner, TD, and, Mitchell, JA. 2002. Cyclooxygenase-3 (COX-3): Filling in the gaps toward a COX continuum?. Proceedings of the National Academy of Science of the United States of America, 99: 13371-13373. (Pubitemid 35215385)